37 Matching Annotations
  1. Mar 2024
  2. www.sciencedirect.com www.sciencedirect.com
    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
    1
    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.cell.2024.02.023

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    sciencedirect.com/science/article/pii/S0092867424002253
  3. Feb 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prostate cancer
    1
    1. scibot 28 Feb 2024
      RRID:AB_331707

      DOI: 10.1016/j.isci.2024.108794

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879682/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Heterogeneity in MET Pathway Activation in PDX Models of Osimertinib Resistant EGFR-Driven Lung Cancer
    1
    1. scibot 11 Feb 2024
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      DOI: 10.1158/2767-9764.CRC-23-0321

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    ncbi.nlm.nih.gov/pmc/articles/PMC10851855/
  6. Oct 2023
  7. 52.53.155.43 52.53.155.43
    bqad159-html.html
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    1. scibot 31 Oct 2023
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      DOI: 10.1210/endocr/bqad159

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    52.53.155.43/fadb698104ccd541263e8069783171593188288f/bqad159-html.html
  8. Aug 2023
  9. www.biorxiv.org www.biorxiv.org
    Unraveling Vulnerabilities in Endocrine Therapy-Resistant HER2+/ER+ Breast Cancer
    1
    1. scibot 27 Aug 2023
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      DOI: 10.1101/2023.08.21.554116

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    biorxiv.org/content/10.1101/2023.08.21.554116v1
  10. Feb 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Pseudo-temporal dynamics of chemoresistant triple negative breast cancer cells reveal EGFR/HER2 inhibition as synthetic lethal during mid-neoadjuvant chemotherapy
    1
    1. scibot 11 Feb 2023
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      DOI: 10.1016/j.isci.2023.106064

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    sciencedirect.com/science/article/pii/S2589004223001414
  12. Dec 2022
  13. www.sciencedirect.com www.sciencedirect.com
    KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
    1
    1. scibot 17 Dec 2022
      RRID:AB_331707

      DOI: 10.1016/j.ccell.2022.11.015

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    sciencedirect.com/science/article/pii/S1535610822005621
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    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
    1
    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111653

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    sciencedirect.com/science/article/pii/S2211124722015248
  15. aacrjournals.org aacrjournals.org
    Serial profiling of circulating tumor DNA identifies dynamic evolution of clinically actionable genomic alterations in high-risk neuroblastoma
    1
    1. scibot 03 Dec 2022
      RRID:AB_331707

      DOI: 10.1158/2159-8290.CD-22-0287

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    aacrjournals.org/cancerdiscovery/article/12/12/2800/711177/Serial-Profiling-of-Circulating-Tumor-DNA
  16. Nov 2022
  17. www.sciencedirect.com www.sciencedirect.com
    RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation
    1
    1. scibot 10 Nov 2022
      RRID:AB_331707

      DOI: 10.1016/j.isci.2022.105184

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    sciencedirect.com/science/article/pii/S2589004222014560
  18. Jul 2022
  19. www.sciencedirect.com www.sciencedirect.com
    Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity
    1
    1. scibot 13 Jul 2022
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      DOI: 10.1016/j.ccell.2022.06.006

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    sciencedirect.com/science/article/pii/S1535610822002707
  20. Jun 2022
  21. www.sciencedirect.com www.sciencedirect.com
    Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma
    1
    1. scibot 22 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110991

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    sciencedirect.com/science/article/pii/S221112472200777X
  22. May 2022
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deconvoluting mechanisms of acquired resistance to RAF inhibitors in BRAF V600E mutant human glioma
    1
    1. scibot 18 May 2022
      RRID:AB_331707

      DOI: 10.1158/1078-0432.CCR-21-2660

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    ncbi.nlm.nih.gov/pmc/articles/PMC8595717/
  24. Jan 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Tissue differences in the exosomal/small extracellular vesicle proteome and their potential as indicators of altered tissue metabolism
    1
    1. scibot 19 Jan 2022
      RRID:AB_331707

      DOI: 10.1016/j.celrep.2021.110277

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    sciencedirect.com/science/article/pii/S2211124721017927
  26. Dec 2021
  27. www.sciencedirect.com www.sciencedirect.com
    Substratum stiffness regulates Erk signaling dynamics through receptor-level control
    1
    1. scibot 29 Dec 2021
      RRID:AB_331707

      DOI: 10.1016/j.celrep.2021.110181

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    sciencedirect.com/science/article/pii/S2211124721016818
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling
    1
    1. scibot 02 Dec 2021
      RRID:AB_331707

      DOI: 10.1158/1535-7163.MCT-20-0640

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    ncbi.nlm.nih.gov/pmc/articles/PMC8172524/
  29. Nov 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities
    1
    1. scibot 24 Nov 2021
      RRID:AB_331707

      DOI: 10.1016/j.celrep.2021.110054

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    sciencedirect.com/science/article/pii/S2211124721015400
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AXL cooperates with EGFR to mediate neutrophil elastase-induced migration of prostate cancer cells
    1
    1. scibot 16 Nov 2021
      RRID:AB_331707

      DOI: 10.1016/j.isci.2021.103270

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    ncbi.nlm.nih.gov/pmc/articles/PMC8567381/
  32. Jul 2021
  33. elifesciences.org elifesciences.org
    Untitled document
    1
    1. scibot 27 Jul 2021
      RRID:AB_331707

      DOI: 10.7554/eLife.19671

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    elifesciences.org/articles/19671
  34. Jun 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma
    1
    1. scibot 04 Jun 2021
      RRID:AB_331707

      DOI: 10.1016/j.ccell.2021.05.002

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    sciencedirect.com/science/article/pii/S1535610821002683
  36. May 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling
    1
    1. scibot 19 May 2021
      RRID:AB_331707

      DOI: 10.7554/eLife.68348

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    ncbi.nlm.nih.gov/pmc/articles/PMC8118655/
  38. Apr 2021
  39. www.sciencedirect.com www.sciencedirect.com
    NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation
    1
    1. scibot 07 Apr 2021
      RRID:AB_331707

      DOI: 10.1016/j.celrep.2021.108949

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    sciencedirect.com/science/article/pii/S2211124721002631
  40. Feb 2021
  41. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
    L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness
    1
    1. scibot 25 Feb 2021
      AB_331707

      DOI: 10.1186/s12964-021-00710-5

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    biosignaling.biomedcentral.com/articles/10.1186/s12964-021-00710-5
  42. Nov 2020
  43. www.sciencedirect.com www.sciencedirect.com
    Ablation of Fat Cells in Adult Mice Induces Massive Bone Gain
    1
    1. scibot 20 Nov 2020
      RRID:AB_331707

      DOI: 10.1016/j.cmet.2020.09.011

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    sciencedirect.com/science/article/pii/S1550413120304897
  44. Sep 2020
  45. www.sciencedirect.com www.sciencedirect.com
    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
    1
    1. scibot 26 Sep 2020
      RRID:AB_331707

      DOI: 10.1016/j.ccell.2019.12.006

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    sciencedirect.com/science/article/pii/S1535610819305768
  46. www.sciencedirect.com www.sciencedirect.com
    Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling
    1
    1. scibot 25 Sep 2020
      RRID:AB_331707

      DOI: 10.1016/j.celrep.2020.02.014

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    sciencedirect.com/science/article/pii/S2211124720301686
  47. www.sciencedirect.com www.sciencedirect.com
    Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis
    1
    1. scibot 15 Sep 2020
      RRID:AB_331707

      DOI: 10.1016/j.cmet.2020.04.011

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    sciencedirect.com/science/article/pii/S1550413120301935
  48. www.sciencedirect.com www.sciencedirect.com
    Challenges and Reinterpretation of Antibody-Based Research on Phosphorylation of Tyr307 on PP2Ac
    1
    1. scibot 13 Sep 2020
      RRID:AB_331707

      DOI: 10.1016/j.celrep.2020.02.012

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    sciencedirect.com/science/article/pii/S2211124720301662
  49. Jan 2020
  50. www.sciencedirect.com www.sciencedirect.com
    Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_331707

      DOI: 10.1016/j.ccell.2019.05.013

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    sciencedirect.com/science/article/pii/S1535610819302557
  51. www.sciencedirect.com www.sciencedirect.com
    LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion
    1
    1. scibot 13 Jan 2020
      RRID:AB_331707

      DOI: 10.1016/j.celrep.2019.11.063

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    sciencedirect.com/science/article/pii/S2211124719315542
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3
    1
    1. scibot 13 Jan 2020
      RRID:AB_331707

      DOI: 10.1073/pnas.1805298115

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    ncbi.nlm.nih.gov/pmc/articles/PMC6196494/
  53. Nov 2018
  54. www.sciencedirect.com www.sciencedirect.com
    COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking
    1
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    sciencedirect.com/science/article/pii/S2211124718309835
  55. www.sciencedirect.com www.sciencedirect.com
    Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR
    1
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    sciencedirect.com/science/article/pii/S2451945618301193
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
  57. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Single Particle Imaging of Polarized Hepatoma Organoids upon Hepatitis C Virus Infection Reveals an Ordered and Sequential Entry Process
    1
    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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    pubmed.ncbi.nlm.nih.gov/29544098/
  58. Nov 2017
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors
    2
    1. scibot 08 Nov 2017
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      Curator: @gabimpine

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    2. scibot 08 Nov 2017
      AB_331707

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    ncbi.nlm.nih.gov/pmc/articles/PMC5241115/