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Structural and functional effects of phosphopriming and scaffolding in the kinase GSK-3β

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  DOI: 10.1126/scisignal.ado0881
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11461088/
Jul 2025
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Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis

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1. scibot 08 Jul 2025
  
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  DOI: 10.1038/s42003-025-08440-x
  
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nature.com/articles/s42003-025-08440-x
Apr 2025
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PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma

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1. scibot 08 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115541
  
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sciencedirect.com/science/article/pii/S2211124725003122
Mar 2025
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ARHGAP12 and ARHGAP29 exert distinct regulatory effects on switching between two cell morphological states through GSK-3 activity

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1. scibot 07 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115361
  
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sciencedirect.com/science/article/pii/S2211124725001329
Feb 2025
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Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway

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  DOI: 10.1016/j.xcrm.2025.101941
  
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sciencedirect.com/science/article/pii/S266637912500014X
Jan 2025
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The de novo synthesis of GABA and its gene regulatory function control hepatocellular carcinoma metastasis

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.devcel.2024.12.007
  
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sciencedirect.com/science/article/pii/S1534580724007299
Sep 2024
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IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis

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1. scibot 26 Sep 2024
  
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sciencedirect.com/science/article/pii/S1550413124003644
Aug 2024
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A Mosaic Variant in CTNNB1/β-catenin as a Novel Cause for Osteopathia Striata With Cranial Sclerosis

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1. scibot 02 Aug 2024
  
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  DOI: 10.1210/clinem/dgad757
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgad757/7508140
Apr 2024
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Inhibition of NEK2 Promotes Chemosensitivity and Reduces KSHV-positive Primary Effusion Lymphoma Burden

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1. scibot 11 Apr 2024
  
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  DOI: 10.1158/2767-9764.CRC-23-0430
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11003453/
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Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway

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  DOI: 10.1016/j.celrep.2024.114065
  
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sciencedirect.com/science/article/pii/S2211124724003930
Mar 2024
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Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis

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1. scibot 26 Mar 2024
  
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  RRID:AB_331729
  
  DOI: 10.1038/s41388-024-03008-1
  
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nature.com/articles/s41388-024-03008-1
Jan 2024
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miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.

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1. scibot 18 Jan 2024
  
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  RRID:AB_331729
  
  DOI: 10.1016/j.isci.2023.108650
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10788216/
Dec 2023
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AID-induced CXCL12 upregulation enhances castration-resistant prostate cancer cell metastasis by stabilizing β-catenin expression

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1. scibot 21 Dec 2023
  
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  RRID:AB_331729
  
  DOI: 10.1016/j.isci.2023.108523
  
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sciencedirect.com/science/article/pii/S2589004223026007
Jun 2023
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Deneddylating enzyme SENP8 regulates neuronal development

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1. scibot 01 Jun 2023
  
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  DOI: 10.1111/jnc.15797
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15797
May 2023
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eIF4E phosphorylation recruits β-catenin to mRNA cap and promotes Wnt pathway translation in dentate gyrus LTP maintenance

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1. scibot 13 May 2023
  
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  RRID:AB_331729
  
  DOI: 10.1016/j.isci.2023.106649
  
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sciencedirect.com/science/article/pii/S2589004223007265
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity

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1. scibot 24 Mar 2023
  
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  DOI: 10.1016/j.isci.2023.106289
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10030912/
Jan 2023
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CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis

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1. scibot 24 Jan 2023
  
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  RRID:AB_331729
  
  DOI: 10.1016/j.celrep.2023.112005
  
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sciencedirect.com/science/article/pii/S2211124723000165
Oct 2022
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Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy

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1. scibot 20 Oct 2022
  
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  RRID:AB_331729
  
  DOI: 10.1016/j.immuni.2022.09.014
  
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sciencedirect.com/science/article/pii/S1074761322005088
Sep 2022
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Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development

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1. scibot 15 Sep 2022
  
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  DOI: 10.1016/j.celrep.2022.111350
  
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sciencedirect.com/science/article/pii/S2211124722011780
Aug 2022
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Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock

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1. scibot 17 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111208
  
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sciencedirect.com/science/article/pii/S2211124722010257
Mar 2022
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Neddylation is essential for β-catenin degradation in Wnt signaling pathway

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1. scibot 23 Mar 2022
  
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  RRID:AB_331729
  
  DOI: 10.1016/j.celrep.2022.110538
  
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sciencedirect.com/science/article/pii/S2211124722002790
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1

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1. scibot 04 Mar 2022
  
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  RRID:AB_331729WB
  
  DOI: 10.7554/eLife.57593
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8880992/
Feb 2022
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Liquidambaric acid inhibits Wnt/β-catenin signaling and colon cancer via targeting TNF receptor-associated factor 2

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1. scibot 02 Feb 2022
  
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  RRID:AB_331729
  
  DOI: 10.1016/j.celrep.2022.110319
  
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sciencedirect.com/science/article/pii/S2211124722000304
Nov 2021
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OGDHL Ameliorates Cognitive Impairment and Alzheimer's Disease-Like Pathology via Activating Wnt/β-catenin signaling in Alzheimer's Disease Mice

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1. scibot 17 Nov 2021
  
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  9561
  
  DOI: 10.1016/j.bbr.2021.113673
  
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sciencedirect.com/science/article/pii/S0166432821005611
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Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment

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1. scibot 13 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109974
  
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sciencedirect.com/science/article/pii/S2211124721014534
Sep 2021
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Full-length isoform transcriptome of the developing human brain provides further insights into autism

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1. scibot 01 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109631
  
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sciencedirect.com/science/article/pii/S2211124721010743
Aug 2021
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Untitled document

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1. scibot 10 Aug 2021
  
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  RRID:AB_331729
  
  DOI: 10.1016/j.molcel.2018.11.003
  
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sciencedirect.com/science/article/pii/S1097276518309456
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines

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1. scibot 07 Aug 2021
  
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  RRID:AB_331729
  
  DOI: 10.1016/j.isci.2021.102807
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8313754/
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Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation

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1. scibot 05 Aug 2021
  
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  DOI: 10.1016/j.molcel.2021.07.013
  
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sciencedirect.com/science/article/pii/S1097276521005827
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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  DOI: 10.1016/j.celrep.2018.12.023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6315376/
May 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein

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1. scibot 20 May 2021
  
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  Rabbit anti-phospho-β-catenin (Ser33/37/Thr41)
  
  DOI: 10.1002/ijc.33562
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33562
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Distinct Spatiotemporally Dynamic Wnt-Secreting Niches Regulate Proximal Airway Regeneration and Aging

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1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.06.019
  
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sciencedirect.com/science/article/pii/S1934590920302861
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A Dual Protein-mRNA Localization Screen Reveals Compartmentalized Translation and Widespread Co-translational RNA Targeting

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1. scibot 05 May 2021
  
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  DOI: 10.1016/j.devcel.2020.07.010
  
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sciencedirect.com/science/article/pii/S1534580720305840
Apr 2021
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The Scaffold Protein Axin Promotes Signaling Specificity within the Wnt Pathway by Suppressing Competing Kinase Reactions

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1. scibot 27 Apr 2021
  
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  DOI: 10.1016/j.cels.2020.05.002
  
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sciencedirect.com/science/article/pii/S240547122030185X
www.nature.com www.nature.com

Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia

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1. scibot 17 Apr 2021
  
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  RRID:AB_331729
  
  DOI: 10.1038/s41593-020-00794-1
  
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nature.com/articles/s41593-020-00794-1
Feb 2021
journals.physiology.org journals.physiology.org

Identification of a novel selective and potent inhibitor of glycogen synthase kinase-3

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  DOI: 10.1152/ajpcell.00061.2019
  
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journals.physiology.org/doi/abs/10.1152/ajpcell.00061.2019
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Homogentisic acid affects human osteoblastic functionality by oxidative stress and alteration of the Wnt/β‐catenin signaling pathway

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  DOI: 10.1002/jcp.29575
  
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onlinelibrary.wiley.com/doi/10.1002/jcp.29575
Jan 2021
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Schistosoma mansoni eggs induce Wnt/β-catenin signaling and activate the protooncogene c-Jun in human and hamster colon

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  DOI: 10.1038/s41598-020-79450-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7758332/
Dec 2020
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Identification of a novel selective and potent inhibitor of glycogen synthase kinase-3

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1. scibot 07 Dec 2020
  
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  DOI: 10.1152/ajpcell.00061.2019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6962522/
Nov 2020
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In utero exposure to maternal diabetes impairs nephron progenitor differentiation

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  DOI: 10.1152/ajprenal.00204.2019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6879946/
Sep 2020
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Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase

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  DOI: 10.1016/j.celrep.2020.107922
  
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sciencedirect.com/science/article/pii/S2211124720309037
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Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis

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  DOI: 10.1016/j.cmet.2020.03.010
  
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sciencedirect.com/science/article/pii/S155041312030125X
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Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue

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  DOI: 10.1007/s00018-020-03485-z
  
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Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells

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  DOI: 10.1016/j.cell.2020.03.006
  
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High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor that Promotes Airway Basal Stem Cell Homeostasis

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  DOI: 10.1016/j.celrep.2020.01.059
  
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sciencedirect.com/science/article/pii/S221112472030084X
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WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop

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1. scibot 04 Sep 2020
  
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  DOI: 10.1016/j.celrep.2018.12.023
  
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cell.com/cell-reports/abstract/S2211-1247(18)31953-3
journals.physiology.org journals.physiology.org

Identification of a novel selective and potent inhibitor of glycogen synthase kinase-3 | American Journal of Physiology-Cell Physiology

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1. scibot 03 Sep 2020
  
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  DOI: 10.1152/ajpcell.00061.2019
  
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journals.physiology.org/doi/full/10.1152/ajpcell.00061.2019
Jan 2020
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Complement C3a induces axonal hypomyelination in the periventricular white matter through activation of WNT/β‐catenin signal pathway in septic neonatal rats experimentally induced by lipopolysaccharide

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1. scibot 13 Jan 2020
  
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  DOI: 10.1111/bpa.12798
  
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onlinelibrary.wiley.com/doi/full/10.1111/bpa.12798
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Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex

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  DOI: 10.7554/eLife.49376
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6890460/
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Untitled document

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  DOI: 10.1016/j.celrep.2019.03.028
  
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sciencedirect.com/science/article/pii/S2211124719303444
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Untitled document

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sciencedirect.com/science/article/pii/S2211124718319533
Nov 2018
europepmc.org europepmc.org

A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3α and GSK3β in Regulating Embryonic Stem Cell Fate.

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1. scibot 05 Nov 2018
  
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europepmc.org/articles/PMC5851779/
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Lithium Inhibits GSK3β and Augments GluN2A Receptor Expression in the Prefrontal Cortex

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ncbi.nlm.nih.gov/pmc/articles/PMC5799274/