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PKD and scaffold NHERF1 mediate hypoxia-induced gene expression in 3T3-L1 adipocytes

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Aug 2025
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jme-JME-25-0011-html.html

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Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer

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Jun 2025
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Dynamic decoding of VEGF signaling and coordinated control of multiple phenotypes by the Src-TEM4-YAP pathway

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Feb 2025
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Metabotropic NMDAR Signaling Contributes to Sex Differences in Synaptic Plasticity and Episodic Memory

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Jan 2025
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Indole and Coumarin Derivatives Targeting EEF2K in Aβ Folding Reporter Cells

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Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10

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Dec 2024
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1-s2.0-S2589004224028980-main-html.html

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Nov 2024
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USP7 deubiquitinates KRAS and promotes non-small cell lung cancer

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Aug 2024
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Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

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Untitled document

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onlinelibrary.wiley.com/doi/10.1002/jnr.23999/full
Jul 2024
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A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins

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Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

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Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer

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Therapeutic expression of RAS Degrader RRSP in Pancreatic Cancer via Nanocarrier-mediated mRNA delivery

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ncbi.nlm.nih.gov/pmc/articles/PMC11212117/
May 2024
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BPS Publications

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Mar 2024
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Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response

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Feb 2024
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An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prostate cancer

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Metabotropic NMDA Receptor Signaling Contributes to Sex Differences in Synaptic Plasticity and Episodic Memory

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Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress

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Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice

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Jan 2024
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PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis

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cwad087-html.html

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Nov 2023
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Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

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cwad087-html.html

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Oct 2023
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ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer

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Sep 2023
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TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation

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Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion

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Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer

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Jul 2023
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A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins

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Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition

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Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling

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Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling

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Oncogenic K-Ras suppresses global miRNA function

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Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

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Acetate controls endothelial-to-mesenchymal transition

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How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view

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Prominin-1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice

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Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21

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VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection

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Lysimachiae Herba Inhibits Inflammatory Reactions and Improves Lipopolysaccharide/D-Galactosamine-Induced Hepatic Injury

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A new paradigm for epidermal growth factor receptor expression exists in PTC and NIFTP regulated by microRNAs

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Phenotypic plasticity and reduced tissue retention of exhausted tumor-infiltrating T cells following neoadjuvant immunotherapy in head and neck cancer

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Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma

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Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex

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Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines

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Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin

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Opioids Cause Sex-Specific Vascular Changes via Cofilin-Extracellular Signal-Regulated Kinase Signaling: Female Mice Present Higher Risk of Developing Morphine-Induced Vascular Dysfunction than Male Mice

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Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding

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Neuregulin-1 signaling regulates cytokines and chemokines expression and secretion in granulosa cell

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A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions

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Proteolytic pan-RAS cleavage leads to tumor regression in patient-derived pancreatic cancer xenografts

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Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma

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Peripheral nerve fibroblasts secrete neurotrophic factors to promote axon growth of motoneurons

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Regulation of GTPase function by autophosphorylation

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Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer

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Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease

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c-FOS drives reversible basal to squamous cell carcinoma transition

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Tissue environment, not ontogeny, defines murine intestinal intraepithelial T lymphocytes

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Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis

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Chronic VEGFR-3 signaling preserves dendritic arborization and sensitization under stress

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Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC

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Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2

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Differential Effects of Toll-Like Receptor Activation and Differential Mediation by MAP Kinases of Immune Responses in Microglial Cells

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Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

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Table 2 | Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition

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A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways

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The E3 ligase TRAF4 Promotes IGF Signaling by Mediating Atypical Ubiquitination of IRS-1

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Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells

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Discovery of Covalent MKK4/7 Dual Inhibitor

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LncRNA RP6‐65G23.1 accelerates proliferation and inhibits apoptosis via p‐ERK1/2/p‐AKT signaling pathway on keratinocytes

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BPS Publications

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Weak acids induce PGE 2 production in human oesophageal cells: novel mechanisms underlying GERD symptoms

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11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma

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Injectable Hydrogel Containing Tauroursodeoxycholic Acid for Anti-neuroinflammatory Therapy After Spinal Cord Injury in Rats

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Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway

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Protocol for Barcoding T Cells Combined with Timed Stimulations

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Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness

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Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling

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ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms

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Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution

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Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

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Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling

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  rabbit anti-pERK1/2
  
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Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2

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Salmonella Coiled-Coil- and TIR-Containing TcpS Evades the Innate Immune System and Subdues Inflammation

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Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors

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Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D

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Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis

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CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity

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Regulation of T‐type Ca2+ channel expression by interleukin‐6 in sensory‐like ND7/23 cells post‐herpes simplex virus (HSV‐1) infection

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Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells

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Stem Cell Proliferation Is Kept in Check by the Chromatin Regulators Kismet/CHD7/CHD8 and Trr/MLL3/4

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  DOI: 10.1016/j.celrep.2019.03.028
  
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Nov 2018
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Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding

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RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis

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Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade

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Systematic Functional Annotation of Somatic Mutations in Cancer

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Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf)

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The Response of Prostate Smooth Muscle Cells to Testosterone Is Determined by the Subcellular Distribution of the Androgen Receptor

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Untitled document

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Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity

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Nov 2017
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Gonadotropin-Dependent Neuregulin-1 Signaling Regulates Female Rat Ovarian Granulosa Cell Survival

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Dual effect of serotonin on the dendritic growth of cultured hippocampal neurons: Involvement of 5-HT1A and 5-HT7 receptors

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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45

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Modulation of Autophagy by BDNF Underlies Synaptic Plasticity

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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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Soluble cpg15 from Astrocytes Ameliorates Neurite Outgrowth Recovery of Hippocampal Neurons after Mouse Cerebral Ischemia

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Genetic disruption of the core circadian clock impairs hippocampus-dependent memory

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