144 Matching Annotations
  1. Aug 2024
  2. www.sciencedirect.com www.sciencedirect.com
    MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation
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    1. scibot 29 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724010337
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    SIRT1 improves lactate homeostasis in the brain to alleviate parkinsonism via deacetylation and inhibition of PKM2
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    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.xcrm.2024.101684

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    sciencedirect.com/science/article/pii/S2666379124004051
  4. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Distinguishing pathophysiological features of heart failure with reduced and preserved ejection fraction: A comparative analysis of two mouse models
    1
    1. scibot 21 Aug 2024
      RRID:AB_331

      DOI: 10.1113/JP286410

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP286410
  5. 52.53.155.43 52.53.155.43
    Supplemental_Materials (1)-html.html
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    1. scibot 02 Aug 2024
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      DOI: 10.2337/figshare.21183496

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    52.53.155.43/d88ad76d933f2aaeca09b3b316a302f76c99bbf1/Supplemental_Materials (1)-html.html
  6. Jul 2024
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    Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells
    1
    1. scibot 31 Jul 2024
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    sciencedirect.com/science/article/pii/S1934590924002534
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
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    1. scibot 16 Jul 2024
      RRID:AB_331805

      DOI: 10.1016/j.celrep.2020.107695

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    ncbi.nlm.nih.gov/pmc/articles/PMC7262597/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YZL-51N functions as a selective inhibitor of SIRT7 by NAD+ competition to impede DNA damage repair
    1
    1. scibot 01 Jul 2024
      RRID:AB_331805

      DOI: 10.1016/j.isci.2024.110014

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    ncbi.nlm.nih.gov/pmc/articles/PMC11214487/
  10. May 2024
  11. 52.53.155.43 52.53.155.43
    SIRT1 mediates the antagonism of Wnt/β-catenin pathway by vitamin D in colon carcinoma cells
    1
    1. scibot 04 May 2024
      Cell Signaling  Cat# 9441

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    52.53.155.43/696f49a3546de66e1af8cab87bfc89cda4bd0257/2024.01.21.576539v1.full-html.html
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    Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration
    1
    1. scibot 03 May 2024
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    sciencedirect.com/science/article/pii/S0092867424004008
  13. Apr 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The acetylation of MDH1 and IDH1 is associated with energy metabolism in acute liver failure
    1
    1. scibot 28 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11039345/
  15. 52.53.155.43 52.53.155.43
    TSPYL2 induces renal ischemia-reperfusion injury through SREBP-2/ACMSD signaling
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    1. scibot 11 Apr 2024
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    52.53.155.43/6757b9d9d924ce64a3f7cf8064c4794b752c3bb9/1-s2.0-S2589004224008162-main-html.html
  16. www.sciencedirect.com www.sciencedirect.com
    Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss
    1
    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S1550413124000536
  17. Mar 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
    1
    1. scibot 19 Mar 2024
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      DOI: 10.7554/eLife.87386

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942603/
  19. www.sciencedirect.com www.sciencedirect.com
    Securin acetylation prevents precocious separase activation and premature sister chromatid separation
    4
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.cub.2024.02.038

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    sciencedirect.com/science/article/pii/S0960982224001805
  20. Feb 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.isci.2024.108943

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    ncbi.nlm.nih.gov/pmc/articles/PMC10850750/
  22. Jan 2024
  23. link.springer.com link.springer.com
    Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction
    1
    1. scibot 01 Jan 2024
      RRID:AB_331805

      DOI: 10.1007/s00125-021-05431-5

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    link.springer.com/article/10.1007/s00125-021-05431-5
  24. Dec 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
    1
    1. scibot 22 Dec 2023
      RRID:AB_331805

      DOI: 10.1016/j.xcrm.2023.101342

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    sciencedirect.com/science/article/pii/S2666379123005591
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions
    1
    1. scibot 02 Dec 2023
      RRID:AB_331805

      DOI: 10.1016/j.isci.2023.108446

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    ncbi.nlm.nih.gov/pmc/articles/PMC10687339/
  27. www.sciencedirect.com www.sciencedirect.com
    Small-molecule TIP60 inhibitors enhance regulatory T cell induction through TIP60-P300 acetylation crosstalk
    1
    1. scibot 01 Dec 2023
      RRID:AB_331805

      DOI: 10.1016/j.isci.2023.108491

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    sciencedirect.com/science/article/pii/S2589004223025683
  28. Nov 2023
  29. www.embopress.org www.embopress.org
    SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1
    1
    1. scibot 03 Nov 2023
      RRID:AB_331805

      DOI: 10.15252/embr.202357500

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    embopress.org/doi/10.15252/embr.202357500
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress
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    1. scibot 02 Nov 2023
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      DOI: 10.7554/eLife.87419

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    ncbi.nlm.nih.gov/pmc/articles/PMC10615369/
  31. Oct 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer
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    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.cmet.2023.10.002

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    sciencedirect.com/science/article/pii/S1550413123003716
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine
    1
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      DOI: 10.3892/ol.2023.14067

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    ncbi.nlm.nih.gov/pmc/articles/PMC10561147/
  34. www.cell.com www.cell.com
    ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113099

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    cell.com/cell-reports/abstract/S2211-1247(23)01110-5
  35. Sep 2023
  36. www.sciencedirect.com www.sciencedirect.com
    RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.molcel.2023.08.029

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    sciencedirect.com/science/article/pii/S1097276523006937
  37. www.nature.com www.nature.com
    Acetylation reprograms MITF target selectivity and residence time
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    1. scibot 29 Sep 2023
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      DOI: 10.1038/s41467-023-41793-7

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      DOI: 10.1038/s41467-023-41793-7

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    nature.com/articles/s41467-023-41793-7
  38. Jul 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis
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    sciencedirect.com/science/article/pii/S1550413123002231
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    Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication
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      DOI: 10.1016/j.chom.2023.06.013

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    sciencedirect.com/science/article/abs/pii/S1931312823002640
  41. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html
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      DOI: 10.1111/bph.16193

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    52.53.155.43/51180316abfac9593501c4c683749a3ad6cad477/British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html
  42. 52.53.155.43 52.53.155.43
    GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner
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      DOI: 10.15252/embr.202256437

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  43. www.sciencedirect.com www.sciencedirect.com
    HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway
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      DOI: 10.1016/j.celrep.2023.112731

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    sciencedirect.com/science/article/pii/S2211124723007428
  44. Jun 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Reduced acetylation of TFAM promotes bioenergetic dysfunction in the failing heart
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      DOI: 10.1016/j.isci.2023.106942

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    sciencedirect.com/science/article/pii/S2589004223010192
  46. May 2023
  47. www.sciencedirect.com www.sciencedirect.com
    IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
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      DOI: 10.1016/j.molcel.2023.05.011

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    sciencedirect.com/science/article/pii/S1097276523003350
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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      DOI: 10.1002/cac2.12332

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    onlinelibrary.wiley.com/doi/10.1002/cac2.12332
  49. Apr 2023
  50. www.sciencedirect.com www.sciencedirect.com
    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
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      DOI: 10.1016/j.celrep.2023.112372

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    sciencedirect.com/science/article/pii/S2211124723003832
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    Protocol to purify the histone deacetylase SIRT6 and assess its activity in vitro
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      DOI: 10.1016/j.xpro.2023.102206

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    sciencedirect.com/science/article/pii/S2666166723001648
  52. Jan 2023
  53. www.sciencedirect.com www.sciencedirect.com
    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
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      DOI: 10.1016/j.ccell.2022.12.008

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  54. Nov 2022
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    Autophagy promotes cell survival by maintaining NAD levels
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    Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis
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    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
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  58. Oct 2022
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    Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation
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  60. Aug 2022
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    The redox cycling of STAT2 maintains innate immune homeostasis
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  62. Jul 2022
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    The role and mechanism of CREBH regulating SIRT3 in metabolic associated fatty liver disease
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    Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice
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  66. Jun 2022
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    Evidence that HDAC7 acts as an epigenetic “reader” of AR acetylation through NCoR-HDAC3 dissociation
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    Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling
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    Hydroxysafflor Yellow A Blocks HIF-1α Induction of NOX2 and Protects ZO-1 Protein in Cerebral Microvascular Endothelium
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    The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function
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    Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation
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  81. Jan 2022
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  83. Dec 2021
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    Transcription Factor ChREBP Mediates High Glucose-Evoked Increase in HIF-1α Content in Epithelial Cells of Renal Proximal Tubules
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    NAD kinase sustains lipogenesis and mitochondrial metabolismthrough fatty acid synthesis
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    SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes
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  88. Nov 2021
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  91. Oct 2021
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  93. Sep 2021
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  95. Aug 2021
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    Ketogenesis impact on liver metabolism revealed by proteomics of lysine β-hydroxybutyrylation
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    Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis
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    Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation
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  105. Jul 2021
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    Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
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  109. www.jneurosci.org www.jneurosci.org
    Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling
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  110. www.sciencedirect.com www.sciencedirect.com
    Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miR-125-chinmo pathway regulates dietary restriction-dependent enhancement of lifespan in Drosophila
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  113. May 2021
  114. www.sciencedirect.com www.sciencedirect.com
    Propionate induces intestinal oxidative stress via Sod2 propionylation in zebrafish
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    SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
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    Mitochondrial SIRT3 confers neuroprotection in Huntington’s disease by regulation of oxidative challenges and mitochondrial dynamics
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      Acetyl-lysine (anti-rabbit)

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    Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells
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  118. Apr 2021
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    NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
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    Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells
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    Tau seeds are subject to aberrant modifications resulting in distinct signatures
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  122. Mar 2021
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    Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction
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  124. Feb 2021
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    Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
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  126. www.nature.com www.nature.com
    Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress
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  127. Jan 2021
  128. www.frontiersin.org www.frontiersin.org
    Melatonin Lowers HIF-1α Content in Human Proximal Tubular Cells (HK-2) Due to Preventing Its Deacetylation by Sirtuin 1
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy
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  130. Nov 2020
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    Loss of Muscle Carnitine Palmitoyltransferase 2 Prevents Diet-Induced Obesity and Insulin Resistance despite Long-Chain Acylcarnitine Accumulation
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  132. Sep 2020
  133. www.cell.com www.cell.com
    PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
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  135. www.sciencedirect.com www.sciencedirect.com
    Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis
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    Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sirt1-inducible deacetylation of p21 promotes cardiomyocyte proliferation
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    Phosphorylation-Regulated Activation of the Arabidopsis RRS1-R/RPS4 Immune Receptor Complex Reveals Two Distinct Effector Recognition Mechanisms
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    Acetylation Stabilizes Phosphoglycerate Dehydrogenase by Disrupting the Interaction of E3 Ligase RNF5 to Promote Breast Tumorigenesis
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    Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2
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  141. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      anti‐Acetyl‐Lysine

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  142. journals.physiology.org journals.physiology.org
    Sugar causes obesity and metabolic syndrome in mice independently of sweet taste | American Journal of Physiology-Endocrinology and Metabolism
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      RRID:AB_331805

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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1
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      Acetylated-Lysine

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  144. Jan 2020
  145. www.sciencedirect.com www.sciencedirect.com
    CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation
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    The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections
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    Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
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    Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication
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    Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis
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      RRID:AB_331806

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    Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
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    sciencedirect.com/science/article/pii/S1074761319303322
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    SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism
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    Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring
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    Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7
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      DOI: 10.1016/j.cell.2019.01.016

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    Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
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    HDAC3-selective inhibition activates brown and beige fat through PRDM16
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    Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
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    Vitamin D Switches BAF Complexes to Protect β Cells
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    A Metabolic Basis for Endothelial-to-Mesenchymal Transition
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    A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline
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    EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation
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    NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression
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    Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis
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    Muscle hypertrophy in hypoxia with inflammation is controlled by bromodomain and extra-terminal domain proteins.
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  175. Nov 2017
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    Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice
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      Cell Signaling9441

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    A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice
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      RRID:AB_331805

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    SIRT1 Functions as a Negative Regulator of Eukaryotic Poly(A)RNA Transport
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    Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes
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      AB_331805

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