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Localis-REX: a general protocol for time-resolved spatiofunctional profiling in live cells and C. elegans

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  DOI: 10.64898/2026.10.21.760500
  
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biorxiv.org/content/10.64898/2026.10.21.760500v1
Aug 2026
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GLUT4 plasma translocation in lateral septum GABAergic neurons supports neuronal activation and social familiarity

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  DOI: 10.1016/j.celrep.2026.117854
  
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sciencedirect.com/science/article/pii/S2211124726009320
Jul 2026
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Host transcriptional corepressor TLE1 is commonly exploited by RNA viruses for replication

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  DOI: 10.1016/j.molcel.2026.06.043
  
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sciencedirect.com/science/article/pii/S1097276526004624
Jun 2026
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A role for nucleolin in functional improvement in stroke

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  DOI: 10.1016/j.isci.2026.116134
  
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sciencedirect.com/science/article/pii/S2589004226015099
May 2026
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Diamond-Blackfan anemia gene product RPS19 counteracts SET to maintain p53 transcriptional activity and tumor suppressor function

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  DOI: 10.1016/j.celrep.2026.117333
  
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sciencedirect.com/science/article/pii/S2211124726004110
Apr 2026
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X-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer

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1. scibot 09 Apr 2026
  
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  DOI: 10.1038/s41388-026-03740-w
  
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nature.com/articles/s41388-026-03740-w
Mar 2026
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NAD+ hydrolysis catalyzed by SelO is required for mitochondrial homeostasis

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  DOI: 10.1016/j.cell.2026.01.033
  
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sciencedirect.com/science/article/pii/S0092867426001613
Feb 2026
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Targeting and dissociating HIF2α from the molecular chaperone Hsp70 triggers apoptosis in kidney cancer

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1. scibot 10 Feb 2026
  
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  DOI: 10.1038/s43856-025-01356-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12881505/
Oct 2025
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Regionally mapped astrocytic responses to cortical and white matter stroke show differential roles in astrocyte-induced vascular remodeling

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  DOI: 10.1016/j.neuron.2025.09.023
  
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sciencedirect.com/science/article/pii/S0896627325007111
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Isoformic PD-1 impedes B cell activation and function in HIV-1 infection

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  DOI: 10.1016/j.celrep.2025.116341
  
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sciencedirect.com/science/article/pii/S221112472501112X
Sep 2025
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Argonaute 2 Inhibits RIG-I Signaling via Competition for Viral RNA Binding

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1. scibot 20 Sep 2025
  
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  DOI: 10.1016/j.isci.2025.113391
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12424427/
Aug 2025
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1-s2.0-S2589004225016529-main-html.html

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  DOI: 10.1016
  
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52.53.155.43/4f4fe074a3a34390503819ded993b7919366019b/1-s2.0-S2589004225016529-main-html.html
Jul 2025
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Interdependence of Pasha and Drosha for localization and function of the Microprocessor in C. elegans

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1. scibot 03 Jul 2025
  
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  DOI: 10.1038/s41467-025-60721-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12219410/
May 2025
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GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.neuron.2025.04.033
  
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sciencedirect.com/science/article/pii/S0896627325003459
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The structure of human sweetness

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.021
  
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sciencedirect.com/science/article/pii/S0092867425004568
Feb 2025
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Ligand-induced assembly of antibody variable fragments for the chemical regulation of biological processes

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1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.chembiol.2025.01.007
  
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sciencedirect.com/science/article/pii/S2451945625000303
Dec 2024
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OCIAD1 and prohibitins regulate the stability of the TIM23 protein translocase

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1. scibot 05 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115038
  
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sciencedirect.com/science/article/pii/S2211124724013895
Nov 2024
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Flow cytometry FRET reveals post-translational modifications drive Protein Phosphatase-5 conformational changes in mammalian cells

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1. scibot 17 Nov 2024
  
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  DOI: 10.1016/j.cstres.2024.10.002
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11532808/
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SUMOylation of protein phosphatase 5 regulates phosphatase activity and substrate release

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44319-024-00250-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11549447/
Aug 2024
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Spliceosomal GTPase Eftud2 deficiency-triggered ferroptosis leads to Purkinje cell degeneration

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  DOI: 10.1016/j.neuron.2024.07.020
  
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sciencedirect.com/science/article/pii/S0896627324005427
May 2024
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Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng

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1. scibot 31 May 2024
  
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  DOI: 10.1016/j.immuni.2024.05.006
  
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  DOI: 10.1016/j.immuni.2024.05.006
  
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sciencedirect.com/science/article/pii/S1074761324002590
Oct 2023
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JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113123
  
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sciencedirect.com/science/article/pii/S221112472301135X
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Short C-terminal Musashi-1 proteins regulate pluripotency states in embryonic stem cells

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  DOI: 10.1016/j.celrep.2023.113308
  
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sciencedirect.com/science/article/pii/S2211124723013207
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The FAM104 proteins VCF1/2 promote the nuclear localization of p97/VCP

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1. scibot 05 Oct 2023
  
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  DOI: 10.7554/eLife.92409
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10541173/
Aug 2023
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Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer

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  DOI: 10.1016/j.chembiol.2023.06.026
  
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sciencedirect.com/science/article/abs/pii/S2451945623002064
Jul 2023
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Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery

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  DOI: 10.1016/j.celrep.2023.112807
  
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sciencedirect.com/science/article/pii/S2211124723008185
Jun 2023
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ECPAS/Ecm29-mediated 26S proteasome disassembly is an adaptive response to glucose starvation

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  DOI: 10.1016/j.celrep.2023.112701
  
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sciencedirect.com/science/article/pii/S221112472300712X
May 2023
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MTHFD2 reprograms macrophage polarization by inhibiting PTEN

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  DOI: 10.1016/j.celrep.2023.112481
  
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sciencedirect.com/science/article/pii/S2211124723004928
Apr 2023
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Context-dependent requirement of G protein coupling for Latrophilin-2 in target selection of hippocampal axons

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1. scibot 27 Apr 2023
  
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  DOI: 10.7554/eLife.83529
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10118387/
Mar 2023
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Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin

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  DOI: 10.1016/j.isci.2023.106150
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9986520/
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Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates

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  DOI: 10.1016/j.devcel.2023.02.006
  
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sciencedirect.com/science/article/pii/S1534580723000485
Feb 2023
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A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia

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1. scibot 10 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112099
  
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sciencedirect.com/science/article/pii/S2211124723001109
Jan 2023
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Bump-and-hole engineering of human polypeptide N-acetylgalactosamine transferases to dissect their protein substrates and glycosylation sites in cells

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1. scibot 13 Jan 2023
  
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  DOI: 10.1016/j.xpro.2022.101974
  
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sciencedirect.com/science/article/pii/S2666166722008541
Jul 2022
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A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand

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1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111039
  
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sciencedirect.com/science/article/pii/S2211124722008336
May 2022
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A somatic mutation in moesin drives progression into acute myeloid leukemia

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1. scibot 11 May 2022
  
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  DOI: 10.1126/sciadv.abm9987
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9020775/
Apr 2022
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A somatic mutation in moesin drives progression into acute myeloid leukemia

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1. scibot 30 Apr 2022
  
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  RRID:AB_347227
  
  DOI: 10.1126/sciadv.abm9987
  
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science.org/doi/full/10.1126/sciadv.abm9987
Sep 2021
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The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation

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1. scibot 22 Sep 2021
  
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  RRID:AB_347227
  
  DOI: 10.1016/j.celrep.2021.109731
  
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sciencedirect.com/science/article/pii/S2211124721011803
Jul 2021
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Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers

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1. scibot 28 Jul 2021
  
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  RRID:AB_347227
  
  DOI: 10.1016/j.cell.2021.07.005
  
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sciencedirect.com/science/article/pii/S009286742100831X
Apr 2021
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Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: the polyG diseases

1
1. scibot 22 Apr 2021
  
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  RRID:AB_347227
  
  DOI: 10.1016/j.neuron.2021.03.038
  
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sciencedirect.com/science/article/pii/S0896627321002269
Sep 2020
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Threonine ADP-Ribosylation of Ubiquitin by a Bacterial Effector Family Blocks Host Ubiquitination

1
1. scibot 23 Sep 2020
  
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  RRID:AB_347227
  
  DOI: 10.1016/j.molcel.2020.03.016
  
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sciencedirect.com/science/article/pii/S1097276520301647
www.cell.com www.cell.com

Structure of the Inhibited State of the Sec Translocon

1
1. scibot 07 Sep 2020
  
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  RRID:AB_347227
  
  DOI: 10.1016/j.molcel.2020.06.013
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30398-1
Jan 2020
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NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression

1
1. scibot 13 Jan 2020
  
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  RRID:AB_347227
  
  DOI: 10.1016/j.celrep.2019.06.085
  
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sciencedirect.com/science/article/pii/S2211124719308654
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Truncated BRPF1 Cooperates with Smoothened to Promote Adult Shh Medulloblastoma

1
1. scibot 13 Jan 2020
  
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  RRID:AB_347227
  
  DOI: 10.1016/j.celrep.2019.11.046
  
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sciencedirect.com/science/article/pii/S2211124719315281
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Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis

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1. scibot 13 Jan 2020
  
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  RRID:AB_347227
  
  DOI: 10.1016/j.celrep.2019.07.045
  
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sciencedirect.com/science/article/pii/S2211124719309490
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibitor potency varies widely among tumor-relevant human isocitrate dehydrogenase 1 mutants

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1. scibot 13 Jan 2020
  
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  RRID:AB_347227
  
  DOI: 10.1042/BCJ20180424
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6422176/
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_347227
  
  DOI: 10.1016/j.celrep.2019.01.018
  
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sciencedirect.com/science/article/pii/S2211124719300270
Nov 2017
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact

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1. scibot 08 Nov 2017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5173324/