31 Matching Annotations
  1. Oct 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice
    1
    1. scibot 04 Oct 2024
      AB_354956

      DOI: 10.1016/j.lfs.2024.123085

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    sciencedirect.com/science/article/pii/S0024320524006751
  3. Aug 2024
  4. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
    Absence of Apolipoprotein E is associated with exacerbation of prion pathology and promotes microglial neurodegenerative phenotype
    1
    1. scibot 02 Aug 2024
      AF1729

      DOI: 10.1186/s40478-021-01261-z

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    actaneurocomms.biomedcentral.com/articles/10.1186/s40478-021-01261-z
  5. Jul 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer’s progression
    1
    1. scibot 16 Jul 2024
      RRID:AB_354956

      DOI: 10.1016/j.celrep.2024.114488

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    sciencedirect.com/science/article/pii/S2211124724008179
  7. Jun 2024
  8. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 28 Jun 2024
      RRID:AB_354956

      DOI: 10.1111/bph.16441

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16441
  9. May 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Distinct roles of TREM2 in central nervous system cancers and peripheral cancers
    1
    1. scibot 24 May 2024
      RRID:AB_354956

      DOI: 10.1016/j.ccell.2024.05.001

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    sciencedirect.com/science/article/pii/S1535610824001624
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Antibody engagement with amyloid-beta does not inhibit [11C]PiB binding for PET imaging
    1
    1. scibot 16 May 2024
      RRID:AB_354956

      DOI: 10.1111/jnc.16127

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16127
  12. Apr 2024
  13. aacrjournals.org aacrjournals.org
    Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary
    1
    1. scibot 19 Apr 2024
      RRID:AB_354956

      DOI: 10.1158/2159-8290.CD-23-0299

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    aacrjournals.org/cancerdiscovery/article/13/12/2610/731625/Spatial-and-Temporal-Mapping-of-Breast-Cancer-Lung
  14. Mar 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias
    1
    1. scibot 16 Mar 2024
      AB_354956

      DOI: 10.1038/s44319-024-00077-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10933458/
  16. Feb 2024
  17. www.embopress.org www.embopress.org
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias
    1
    1. scibot 15 Feb 2024
      RRID:AB_354956

      DOI: 10.1038/s44319-024-00077-x

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    embopress.org/doi/10.1038/s44319-024-00077-x
  18. Dec 2023
  19. 52.53.155.43 52.53.155.43
    cd-23-0299-html.html
    1
    1. scibot 01 Dec 2023
      RRID:AB_354956

      DOI: 10.1158/2159-8290.cd-23-0299

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    52.53.155.43/2b6c279d82b7a0e0d491057f5790a1189e93077e/cd-23-0299-html.html
  20. Oct 2023
  21. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Trem2 deficiency attenuates microglial phagocytosis and autophagic-lysosomal activation in white matter hypoperfusion
    1
    1. scibot 20 Oct 2023
      RRID:AB_354956

      DOI: 10.1111/jnc.15987

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15987
  22. 52.53.155.43 52.53.155.43
    BRI2-mediated regulation of TREM2 processing in microglia and its potential implications for Alzheimer’s disease and related dementias
    1
    1. scibot 13 Oct 2023
      RRID:AB_354956

      DOI: 10.1101/2023.06.14.544924

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    52.53.155.43/5afe577c269e488702b5f7086020251c9f5e047d/2023.06.14.544924v1.full-html.html
  23. Jul 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel phenotype of B cells associated with enhanced phagocytic capability and chemotactic function after ischemic stroke
    1
    1. scibot 25 Jul 2023
      RRID:AB_354956

      DOI: 10.4103/1673-5374.371365

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    ncbi.nlm.nih.gov/pmc/articles/PMC10360087/
  25. www.sciencedirect.com www.sciencedirect.com
    Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in mice
    1
    1. scibot 06 Jul 2023
      RRID:AB_354956

      DOI: 10.1016/j.neuron.2023.06.002

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    sciencedirect.com/science/article/pii/S0896627323004373
  26. Apr 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
    1
    1. scibot 09 Apr 2023
      RRID:AB_354956

      DOI: 10.1016/j.isci.2023.106375

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    ncbi.nlm.nih.gov/pmc/articles/PMC10074152/
  28. Feb 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome
    1
    1. scibot 23 Feb 2023
      RRID:AB_354956

      DOI: 10.1016/j.celrep.2023.112133

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    sciencedirect.com/science/article/pii/S2211124723001444
  30. Jan 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development
    1
    1. scibot 28 Jan 2023
      RRID:AB_354956

      DOI: 10.1016/j.immuni.2022.11.013

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    sciencedirect.com/science/article/pii/S1074761322006033
  32. Dec 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Adaptable toolbox to characterize Alzheimer’s disease pathology in mouse models
    1
    1. scibot 04 Dec 2022
      RRID:AB_354956

      DOI: 10.1016/j.xpro.2022.101891

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    sciencedirect.com/science/article/pii/S2666166722007717
  34. Nov 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Plaque contact and unimpaired Trem2 is required for the microglial response to amyloid pathology
    1
    1. scibot 24 Nov 2022
      RRID:AB_354956

      DOI: 10.1016/j.celrep.2022.111686

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    sciencedirect.com/science/article/pii/S2211124722015601
  36. Oct 2022
  37. www.sciencedirect.com www.sciencedirect.com
    TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways
    1
    1. scibot 28 Oct 2022
      RRID:AB_354956

      DOI: 10.1016/j.cell.2022.09.033

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    sciencedirect.com/science/article/pii/S0092867422012521
  38. Jun 2022
  39. 52.53.155.43 52.53.155.43
    The bidirectional lung brain-axis of amyloid-β pathology: ozone dysregulates the peri-plaque microenvironment
    1
    1. scibot 22 Jun 2022
      RRID:AB_354956

      DOI: 10.1093/brain/awac113

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    52.53.155.43/6c7269a8a0c4cf96641f05a6f51be2d6d8c4ab00/awac113 (1)-html.html
  40. 52.53.155.43 52.53.155.43
    awac113-html.html
    1
    1. scibot 18 Jun 2022
      RRID:AB_354956

      DOI: 10.1093/brain/awac113

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    52.53.155.43/30a61ebc09dbd539ad43de2662708a6ef00e0754/awac113-html.html
  41. www.sciencedirect.com www.sciencedirect.com
    Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease
    1
    1. scibot 03 Jun 2022
      RRID:AB_354956

      DOI: 10.1016/j.celrep.2022.110883

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    sciencedirect.com/science/article/pii/S2211124722006581
  42. Sep 2021
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Invasion of phagocytic Galectin 3 expressing macrophages in the diabetic brain disrupts vascular repair
    1
    1. scibot 04 Sep 2021
      RRID:AB_354956

      DOI: 10.1126/sciadv.abg2712

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    ncbi.nlm.nih.gov/pmc/articles/PMC8373127/
  44. Aug 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
    1
    1. scibot 27 Aug 2021
      RRID:AB_354956

      DOI: 10.1016/j.cell.2021.08.002

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    sciencedirect.com/science/article/pii/S0092867421009442
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology
    1
    1. scibot 25 Aug 2021
      RRID:AB_354956

      DOI: 10.1016/j.isci.2021.102942

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    ncbi.nlm.nih.gov/pmc/articles/PMC8369003/
  47. Sep 2020
  48. elifesciences.org elifesciences.org
    Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models
    1
    1. scibot 03 Sep 2020
      RRID:AB_354956

      DOI: 10.7554/eLife.54083

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    elifesciences.org/articles/54083
  49. Jan 2020
  50. www.sciencedirect.com www.sciencedirect.com
    TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer’s Disease
    1
    1. scibot 13 Jan 2020
      RRID:AB_354956

      DOI: 10.1016/j.neuron.2019.06.010

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S0896627319305604
  51. www.sciencedirect.com www.sciencedirect.com
    TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge
    1
    1. scibot 13 Jan 2020
      RRID:AB_354956

      DOI: 10.1016/j.neuron.2019.12.007

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    sciencedirect.com/science/article/pii/S0896627319310499
  52. Nov 2018
  53. www.sciencedirect.com www.sciencedirect.com
    The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity
    1
    1. scibot 05 Nov 2018
      RRID:AB_354956

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    sciencedirect.com/science/article/pii/S1074761318301857
  54. www.sciencedirect.com www.sciencedirect.com
    TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S0896627318300564