12 Matching Annotations
  1. Sep 2025
  2. www.biorxiv.org www.biorxiv.org
    Insulin resistance alters cortical inhibitory neurons and microglia to exacerbate Alzheimer’s knock-in mouse phenotypes
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    biorxiv.org/content/10.1101/2025.09.05.674487v1
  3. Oct 2024
  4. www.biorxiv.org www.biorxiv.org
    Trem2 deficiency attenuates breast cancer tumor growth in lean, but not obese or weight loss, mice and is associated with alterations of clonal T cell populations
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    biorxiv.org/content/10.1101/2024.09.25.614811v1
  5. May 2024
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Antibody engagement with amyloid-beta does not inhibit [11C]PiB binding for PET imaging
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16127
  7. Mar 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias
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    ncbi.nlm.nih.gov/pmc/articles/PMC10933458/
  9. Feb 2024
  10. www.embopress.org www.embopress.org
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias
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    embopress.org/doi/10.1038/s44319-024-00077-x
  11. Oct 2023
  12. 52.53.155.43 52.53.155.43
    BRI2-mediated regulation of TREM2 processing in microglia and its potential implications for Alzheimer’s disease and related dementias
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    52.53.155.43/5afe577c269e488702b5f7086020251c9f5e047d/2023.06.14.544924v1.full-html.html
  13. Feb 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome
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    sciencedirect.com/science/article/pii/S2211124723001444
  15. Jan 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development
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    sciencedirect.com/science/article/pii/S1074761322006033
  17. Dec 2022
  18. www.sciencedirect.com www.sciencedirect.com
    Adaptable toolbox to characterize Alzheimer’s disease pathology in mouse models
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    sciencedirect.com/science/article/pii/S2666166722007717
  19. Jun 2022
  20. www.sciencedirect.com www.sciencedirect.com
    Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S2211124722006581
  21. Aug 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
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    sciencedirect.com/science/article/pii/S0092867421009442
  23. Dec 2020
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions
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    ncbi.nlm.nih.gov/pmc/articles/PMC7689298/