57 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways
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    sciencedirect.com/science/article/pii/S2211124724013354
  3. Sep 2024
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    Macrophage NRF1 promotes mitochondrial protein turnover via the ubiquitin proteasome system to limit mitochondrial stress and inflammation
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  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal and glial cell alterations involved in the retinal degeneration of the familial dysautonomia optic neuropathy
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  6. Apr 2024
  7. aacrjournals.org aacrjournals.org
    miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress
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    aacrjournals.org/mcr/article/22/4/360/741846/miR-217-Regulates-Normal-and-Tumor-Cell-Fate
  8. Mar 2024
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    Collective cell migration relies on PPP1R15-mediated regulation of the endoplasmic reticulum stress response
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    sciencedirect.com/science/article/pii/S0960982224001568
  10. Nov 2023
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    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
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    sciencedirect.com/science/article/pii/S1097276523008493
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    Differential Ire1 determines loser cell fate in tumor-suppressive cell competition
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  13. Oct 2023
  14. www.cell.com www.cell.com
    Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice
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    cell.com/iscience/abstract/S2589-0042(23)02159-4
  15. May 2023
  16. www.biorxiv.org www.biorxiv.org
    FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis
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      DOI: 10.1101/2023.05.20.541585

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    biorxiv.org/content/10.1101/2023.05.20.541585v1
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piezo1 suppression reduces demyelination after... : Neural Regeneration Research
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154511/
  18. Apr 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Transcriptional-translational conflict is a barrier to cellular transformation and cancer progression
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  20. Mar 2023
  21. aacrjournals.org aacrjournals.org
    Safety and efficacy of intraventricular immunovirotherapy with oncolytic HSV-1 for CNS cancers
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    aacrjournals.org/clincancerres/article/28/24/5419/711437/Safety-and-Efficacy-of-Intraventricular
  22. Jan 2023
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    Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging
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  24. Dec 2022
  25. 52.53.155.43 52.53.155.43
    ccr-22-1382-html.html
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  26. Nov 2022
  27. rupress.org rupress.org
    V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans
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      DOI: 10.1083/jcb.202205045

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    rupress.org/jcb/article/222/1/e202205045/213623/V-ATPase-TORC1-mediated-ATFS-1-translation-directs
  28. Sep 2022
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rates of protein synthesis are maintained in brain but reduced in skeletal muscle during dietary sulfur amino acid restriction
    1
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      DOI: 10.3389/fragi.2022.975129

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    ncbi.nlm.nih.gov/pmc/articles/PMC9450999/
  30. May 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2α via the Hsp70-Bag3 module
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      DOI: 10.1016/j.isci.2022.104282

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    sciencedirect.com/science/article/pii/S2589004222005521
  32. Mar 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication
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    sciencedirect.com/science/article/pii/S1097276522002052
  34. rupress.org rupress.org
    PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen
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    1. scibot 17 Mar 2022
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      DOI: 10.1084/jem.20211498

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    rupress.org/jem/article/219/4/e20211498/213062/PERK-reprograms-hematopoietic-progenitor-cells-to
  35. www.sciencedirect.com www.sciencedirect.com
    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
    1
    1. scibot 15 Mar 2022
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    sciencedirect.com/science/article/pii/S1550413122000547
  36. Jan 2022
  37. journals.plos.org journals.plos.org
    Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection
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      DOI: 10.1371/journal.pntd.0009192

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  38. www.sciencedirect.com www.sciencedirect.com
    Clusterin is involved in mediating the metabolic function of adipose SIRT1
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    sciencedirect.com/science/article/pii/S2589004221016795
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    Cytosolic adaptation to mitochondria-induced proteostatic stress causes progressive muscle wasting
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      DOI: 10.1016/j.isci.2021.103715

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  40. Nov 2021
  41. elifesciences.org elifesciences.org
    mTOR-dependent translation drives tumor infiltrating CD8+ effector and CD4+ Treg cells expansion
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      DOI: 10.7554/eLife.69015

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    elifesciences.org/articles/69015
  42. Aug 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
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    sciencedirect.com/science/article/pii/S1097276521006225
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    Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis
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      DOI: 10.1016/j.molcel.2021.07.041

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    sciencedirect.com/science/article/pii/S1097276521006250
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    Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism
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    sciencedirect.com/science/article/pii/S155041311830192X
  46. elifesciences.org elifesciences.org
    Untitled document
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      DOI: 10.7554/eLife.22871

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    elifesciences.org/articles/22871
  47. Jul 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence
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      DOI: 10.1016/j.devcel.2021.06.009

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    sciencedirect.com/science/article/pii/S1534580721005165
  49. Jun 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Pumilio2 and Staufen2 selectively balance the synaptic proteome
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      DOI: 10.1016/j.celrep.2021.109279

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    sciencedirect.com/science/article/pii/S221112472100646X
  51. May 2021
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21
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      Anti-phosphorylated eIF2α serine 51 (Rabbit monoclonal)

      DOI: 10.7554/eLife.66519

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    ncbi.nlm.nih.gov/pmc/articles/PMC8128440/
  53. www.sciencedirect.com www.sciencedirect.com
    Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress
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      DOI: 10.1016/j.stem.2020.05.007

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    sciencedirect.com/science/article/pii/S1934590920302058
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    A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation
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      DOI: 10.1016/j.cmet.2021.01.013

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    sciencedirect.com/science/article/pii/S1550413121000139
  55. Apr 2021
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism
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      DOI: 10.1016/j.cmet.2020.11.009

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    ncbi.nlm.nih.gov/pmc/articles/PMC7858244/
  57. Mar 2021
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional profiling of the response to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine revealed activation of the eIF2α/ATF4 integrated stress response in two in vitro placental models
    1
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      DOI: 10.1007/s00204-021-03011-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC7961173/
  59. Sep 2020
  60. www.sciencedirect.com www.sciencedirect.com
    ATF4-Induced Warburg Metabolism Drives Over-Proliferation in Drosophila
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      DOI: 10.1016/j.celrep.2020.107659

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    sciencedirect.com/science/article/pii/S2211124720306124
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    Dietary Adaptation of Microbiota in Drosophila Requires NF-κB-Dependent Control of the Translational Regulator 4E-BP
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      DOI: 10.1016/j.celrep.2020.107736

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    sciencedirect.com/science/article/pii/S2211124720307166
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    ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase
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      DOI: 10.1016/j.cmet.2020.03.008

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    sciencedirect.com/science/article/pii/S1550413120301236
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    Evolutionarily Conserved Regulation of Sleep by the Protein Translational Regulator PERK
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      Rabbit anti-phospho-eIF2α (Ser51)

      DOI: 10.1016/j.cub.2020.02.030

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S0960982220302037
  64. www.nature.com www.nature.com
    Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy
    1
    1. scibot 03 Sep 2020
      phospho-eIF2α (Ser51)

      DOI: 10.1038/s41419-020-2642-6

      Resource: (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

      Curator: @Naa003

      SciCrunch record: RRID:AB_390740

      Curator comments: Rabbit Anti-eIF2alpha, phospho (Ser51) Monoclonal Antibody, Unconjugated, Clone 119A11 Cell Signaling Technology Cat# 3597

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    nature.com/articles/s41419-020-2642-6
  65. Jan 2020
  66. www.sciencedirect.com www.sciencedirect.com
    The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4
    1
    1. scibot 13 Jan 2020
      RRID:AB_390740

      DOI: 10.1016/j.neuron.2019.08.007

      Resource: (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

      Curator: @ethanbadger

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      RRID:AB_390740 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627319306919
  67. www.sciencedirect.com www.sciencedirect.com
    Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
    1
    1. scibot 13 Jan 2020
      RRID:AB_390740

      DOI: 10.1016/j.cmet.2019.08.021

      Resource: (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1550413119304954
  68. www.sciencedirect.com www.sciencedirect.com
    NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase
    1
    1. scibot 13 Jan 2020
      RRID:AB_390740

      DOI: 10.1016/j.celrep.2019.10.053

      Resource: (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124719313671
  69. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 13 Jan 2020
      RRID:AB_390740

      DOI: 10.1111/bph.14713

      Resource: (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

      Curator: @Naa003

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      RRID:AB_390740 RRIDCUR:Validated
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14713
  70. www.sciencedirect.com www.sciencedirect.com
    Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration
    1
    1. scibot 13 Jan 2020
      RRID:AB_390740

      DOI: 10.1016/j.neuron.2019.12.014

      Resource: (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

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    sciencedirect.com/science/article/pii/S0896627319310566
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology
    1
    1. scibot 13 Jan 2020
      RRID:AB_390740

      DOI: 10.7554/eLife.39578

      Resource: (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC6426440/
  72. www.sciencedirect.com www.sciencedirect.com
    Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_390740

      DOI: 10.1016/j.ccell.2019.01.018

      Resource: (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

      Curator: @ethanbadger

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      RRID:AB_390740 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819300522
  73. www.sciencedirect.com www.sciencedirect.com
    Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness
    1
    1. scibot 12 Jan 2020
      RRID:AB_390740

      DOI: 10.1016/j.immuni.2019.03.005

      Resource: (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1074761319300950
  74. www.sciencedirect.com www.sciencedirect.com
    Tracing MYC Expression for Small Molecule Discovery
    1
    1. scibot 12 Jan 2020
      RRID:AB_390740

      DOI: 10.1016/j.chembiol.2019.02.007

      Resource: (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S245194561930042X
  75. Nov 2018
  76. www.sciencedirect.com www.sciencedirect.com
    The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis
    1
    1. scibot 05 Nov 2018
      RRID:AB_390740

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    sciencedirect.com/science/article/pii/S0960982218303038
  77. www.jneurosci.org www.jneurosci.org
    Endoplasmic reticulum stress contributes to the loss of newborn hippocampal neurons after traumatic brain injury
    1
    1. scibot 05 Nov 2018
      RRID:AB_390740

      Curator: @bandrow

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      (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

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    jneurosci.org/content/38/9/2372
  78. www.sciencedirect.com www.sciencedirect.com
    Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
    1
    1. scibot 05 Nov 2018
      RRID:AB_390740

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      (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

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    sciencedirect.com/science/article/pii/S153561081730555X
  79. Nov 2017
  80. www.sciencedirect.com www.sciencedirect.com
    The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation
    1
    1. scibot 08 Nov 2017
      RRID:AB_390740

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

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    sciencedirect.com/science/article/pii/S1097276517305798
  81. academic.oup.com academic.oup.com
    Guanabenz Sensitizes Pancreatic β Cells to Lipotoxic Endoplasmic Reticulum Stress and Apoptosis
    1
    1. scibot 08 Nov 2017
      AB_390740

      Curator: @bandrow

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      (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

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    academic.oup.com/endo/article/158/6/1659/3058741/Guanabenz-Sensitizes-Pancreatic-Cells-to-Lipotoxic
  82. elifesciences.org elifesciences.org
    The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
    1
    1. scibot 08 Nov 2017
      AB_390740

      Curator: @kaitlinsung

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      (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

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    elifesciences.org/content/6/e22871
  83. www.sciencedirect.com www.sciencedirect.com
    Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes
    1
    1. scibot 08 Nov 2017
      3597

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 3597, RRID:AB_390740)

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      RRID:AB_390740 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1550413117301705