159 Matching Annotations
  1. Jun 2026
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    Suppression of ATM kinase signaling accelerates cellular senescence
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    sciencedirect.com/science/article/pii/S2213671126001670
  3. Apr 2026
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    The AGPS regulatory variant rs113671272 confers esophageal squamous cell carcinoma susceptibility through allele-specific MEIS3 binding and NF-κB activation in Chinese populations
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    sciencedirect.com/science/article/pii/S2352396426001313
  5. Mar 2026
  6. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226008114-main-html.html
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  7. Feb 2026
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    NF-κB and STAT3 signaling uniquely stratify survival in female glioblastoma patients
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    sciencedirect.com/science/article/pii/S2589004226001367
  9. Dec 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ZFP36-FTO Axis is a Key Regulator of Macrophage Activation and a Druggable Therapeutic Target of Sepsis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12702230/
  11. Nov 2025
  12. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225024678-main-html.html
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  13. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Glutamine synthetase modulates YAP activation by stabilizing LATS under glutamine homeostasis
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    sciencedirect.com:5037/science/article/pii/S2211124725013920
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    Attenuating α-synuclein pathology in mice with in situ engineered astrocytes
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    link.springer.com/article/10.1186/s40035-025-00518-0
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LUBAC modulates CBM complex functions downstream of TRAF6 in T cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12602705/
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  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intracellular Interleukin-1α in Peritumoral Monocytes Induces IL8 Production and Inhibits Mitophagy to Promote Stemness and Metastasis of Hepatocellular Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12580797/
  18. Oct 2025
  19. www.sciencedirect.com www.sciencedirect.com
    The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells
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    sciencedirect.com/science/article/pii/S1097276525008226
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    BST2 expression at astrocyte borders promotes microglial recruitment via the C3/C3aR signaling
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    sciencedirect.com/science/article/pii/S0896627325007512
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    Valence and avidity determine the agonistic activity of anti-TNFR2 nanobody fusion proteins
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    sciencedirect.com/science/article/pii/S2451945625002673
  22. Aug 2025
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    Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression
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    sciencedirect.com/science/article/pii/S1535610825003186
  24. Jul 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate
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    pmc.ncbi.nlm.nih.gov/articles/PMC12208667/
  26. Jun 2025
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    SUV39H1-dependent methyl-degron is a critical regulator of skeletal homeostasis
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    sciencedirect.com/science/article/pii/S2211124725006813
  28. link.springer.com link.springer.com
    RNA polymerase II subunit 5-mediating protein limits TLR4-induced innate immune activation in macrophages by inhibiting IKKβ/NF-κB signaling during sepsis
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    link.springer.com/article/10.1186/s12964-025-02278-w
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    Astrocyte induction of disease-associated microglia is suppressed by acute exposure to fAD neurons in human iPSC triple cultures
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    sciencedirect.com/science/article/pii/S2211124725005480
  30. May 2025
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    Microbiota-derived urocanic acid triggered bytyrosine kinase inhibitors potentiates cancer immunotherapy efficacy
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    sciencedirect.com/science/article/pii/S1931312825001556
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    CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density
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    pmc.ncbi.nlm.nih.gov/articles/PMC12181066/
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    NANS suppresses NF-κB signaling to promote ferroptosis by perturbing iron homeostasis
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    sciencedirect.com/science/article/pii/S2211124725004723
  34. Apr 2025
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Co-targeting BMI1 and MYC to eliminate cancer stem cells in squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12147845/
  36. Feb 2025
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    MIF-ACKR3 causes irreversible fat loss by impairing adipogenesis in cancer cachexia
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    sciencedirect.com/science/article/pii/S155041312500018X
  38. Jan 2025
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anandamide Inhibits Vascular Smooth Muscle Migration, Endothelial Adhesion Protein Expression and Monocyte Adhesion of Human Coronary Artery Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11727187/
  40. www.nature.com www.nature.com
    Intestinal TM6SF2 protects against metabolic dysfunction-associated steatohepatitis through the gut–liver axis
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    nature.com/articles/s42255-024-01177-7
  41. 52.53.155.43 52.53.155.43
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  42. Dec 2024
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SIKs regulate HDAC7 stabilization and cytokine recall in late-stage T cell effector differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC10842463/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCDC134 controls TLR biogenesis through the ER chaperone Gp96
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    pmc.ncbi.nlm.nih.gov/articles/PMC11629888/
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    Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain
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    sciencedirect.com/science/article/pii/S2211124724013676
  46. Nov 2024
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of cathepsin L ameliorates inflammation through the A20/NF-κB pathway in endotoxin-induced acute lung injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC11570319/
  48. Oct 2024
  49. www.sciencedirect.com www.sciencedirect.com
    Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer
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    sciencedirect.com/science/article/pii/S0092867424010729
  50. Sep 2024
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    CD14 is a decision-maker between Fas-mediated death and inflammation
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  52. Aug 2024
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    Septins promote macrophage pyroptosis by regulating gasdermin D cleavage and ninjurin-1-mediated plasma membrane rupture
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    sciencedirect.com/science/article/pii/S2451945624003052
  54. Jul 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
  56. Jun 2024
  57. www.sciencedirect.com www.sciencedirect.com
    IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility
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    sciencedirect.com/science/article/pii/S2211124721002059
  58. Apr 2024
  59. www.sciencedirect.com www.sciencedirect.com
    Chang-Kang-Fang alleviates diarrhea predominant irritable bowel syndrome (IBS-D) through inhibiting TLR4/NF-κB/NLRP3 pathway
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    sciencedirect.com/science/article/pii/S037887412400535X
  60. www.sciencedirect.com www.sciencedirect.com
    6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model
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    sciencedirect.com/science/article/pii/S0006295224002132
  61. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16364
  62. www.sciencedirect.com www.sciencedirect.com
    Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection
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    sciencedirect.com/science/article/pii/S2211124724003358
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    Oncostatin M signaling drives cancer-associated skeletal muscle wasting
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    sciencedirect.com/science/article/pii/S2666379124001666
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983109/
  65. Mar 2024
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10960275/
  67. link.springer.com link.springer.com
    Edaravone dexborneol promotes M2 microglia polarization against lipopolysaccharide-induced inflammation via suppressing TLR4/MyD88/NF-κB pathway
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    link.springer.com/article/10.1007/s00210-024-03045-3
  68. Feb 2024
  69. www.sciencedirect.com www.sciencedirect.com
    ATG5 attenuates inflammatory signaling in mouse embryonic stem cells to control differentiation
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    sciencedirect.com/science/article/pii/S1534580724000467
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
  71. Jan 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 NSP14 MTase activity is critical for inducing canonical NF-κB activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10776897/
  73. dx.doi.org dx.doi.org
    cwad087-html.html
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    dx.doi.org/10.1093/glycob/cwad087
  74. Dec 2023
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62
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    ncbi.nlm.nih.gov/pmc/articles/PMC10730909/
  76. Nov 2023
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC10675918/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10637774/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
  80. dx.doi.org dx.doi.org
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    dx.doi.org/10.1093/glycob/cwad087
  81. Oct 2023
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10571842/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine
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    ncbi.nlm.nih.gov/pmc/articles/PMC10561147/
  84. www.cell.com www.cell.com
    15-keto-PGE2 Alleviates Nonalcoholic Steatohepatitis through its Covalent Modification of NF-κB Factors
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    cell.com/iscience/abstract/S2589-0042(23)02074-6
  85. www.sciencedirect.com www.sciencedirect.com
    ERK1-mediated immunomodulation of mesenchymal stem cells ameliorates inflammatory disorders
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    sciencedirect.com/science/article/pii/S2589004223019454
  86. Aug 2023
  87. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    Hedgehog receptors exert immune-surveillance roles in the epidermis across species
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRP1 Mediated Ferroptosis Reverses Temozolomide Resistance in Glioblastoma via Affecting LCN2/FPN1 Signaling Axis Depended on NFKB2
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    ncbi.nlm.nih.gov/pmc/articles/PMC10374607/
  90. Jul 2023
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    NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62
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    52.53.155.43/5185b06857919afc7fae38712332798a8a903a3a/2023.06.05.543428v1.full-html.html
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    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
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  93. Jun 2023
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10291184/
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    Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts
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    Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas
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    The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB
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  98. May 2023
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    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
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    A LY6E-PHB1-TRIM21 assembly degrades CD14 protein to mitigate LPS-induced inflammatory response
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  101. www.mdpi.com www.mdpi.com
    Lysimachiae Herba Inhibits Inflammatory Reactions and Improves Lipopolysaccharide/D-Galactosamine-Induced Hepatic Injury
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    mdpi.com/2076-3921/10/9/1387/htm
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    Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19
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    sciencedirect.com/science/article/pii/S2666379122002166
  103. Apr 2023
  104. www.cell.com www.cell.com
    Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation
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    cell.com/cancer-cell/abstract/S1535-6108(23)00081-8
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    Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
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  106. Mar 2023
  107. www.sciencedirect.com www.sciencedirect.com
    LMAN1 is a receptor for house dust mite allergens
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  108. Feb 2023
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    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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    sciencedirect.com/science/article/pii/S2589004223002468
  110. Jan 2023
  111. academic.oup.com academic.oup.com
    ERRα attenuates vascular inflammation via enhanced NFκB degradation pathway
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    academic.oup.com/endo/article/164/3/bqac212/6936569
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9804112/
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    ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis
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    sciencedirect.com/science/article/pii/S2211124722018101
  114. Dec 2022
  115. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor necrosis factor is a necroptosis-associated alarmin
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    pmc.ncbi.nlm.nih.gov/articles/PMC9791252/
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vagus nerve stimulation is a potential treatment for ischemic stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC9700118/
  117. Nov 2022
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC9633742/
  119. Oct 2022
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9519628/
  121. Aug 2022
  122. www.sciencedirect.com www.sciencedirect.com
    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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