123 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Chang-Kang-Fang alleviates diarrhea predominant irritable bowel syndrome (IBS-D) through inhibiting TLR4/NF-κB/NLRP3 pathway
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    1. scibot 25 Apr 2024
      4814, Cell Signaling Technology

      DOI: 10.1016/j.jep.2024.118236

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    sciencedirect.com/science/article/pii/S037887412400535X
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    6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model
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    1. scibot 23 Apr 2024
      4814

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    sciencedirect.com/science/article/pii/S0006295224002132
  4. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 11 Apr 2024
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      DOI: 10.1111/bph.16364

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16364
  5. www.sciencedirect.com www.sciencedirect.com
    Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114007

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    sciencedirect.com/science/article/pii/S2211124724003358
  6. www.sciencedirect.com www.sciencedirect.com
    Oncostatin M signaling drives cancer-associated skeletal muscle wasting
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.xcrm.2024.101498

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    sciencedirect.com/science/article/pii/S2666379124001666
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation
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    1. scibot 03 Apr 2024
      RRID:AB_390781

      DOI: 10.1016/j.xcrm.2024.101477

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983109/
  8. Mar 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
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    1. scibot 27 Mar 2024
      RRID:AB_390781

      DOI: 10.4103/1673-5374.389302

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    ncbi.nlm.nih.gov/pmc/articles/PMC10960275/
  10. link.springer.com link.springer.com
    Edaravone dexborneol promotes M2 microglia polarization against lipopolysaccharide-induced inflammation via suppressing TLR4/MyD88/NF-κB pathway
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    1. scibot 20 Mar 2024
      RRID:AB_390781

      DOI: 10.1007/s00210-024-03045-3

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    link.springer.com/article/10.1007/s00210-024-03045-3
  11. Feb 2024
  12. www.sciencedirect.com www.sciencedirect.com
    ATG5 attenuates inflammatory signaling in mouse embryonic stem cells to control differentiation
    1
    1. scibot 22 Feb 2024
      RRID:AB_390781

      DOI: 10.1016/j.devcel.2024.01.026

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    sciencedirect.com/science/article/pii/S1534580724000467
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
    1
    1. scibot 06 Feb 2024
      AB_390781

      DOI: 10.1158/2159-8290.CD-22-1401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
  14. Jan 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 NSP14 MTase activity is critical for inducing canonical NF-κB activation
    1
    1. scibot 12 Jan 2024
      AB_390781

      DOI: 10.1042/BSR20231418

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    ncbi.nlm.nih.gov/pmc/articles/PMC10776897/
  16. dx.doi.org dx.doi.org
    cwad087-html.html
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    1. scibot 11 Jan 2024
      RRID:AB_390781

      DOI: 10.1093/glycob/cwad087

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  17. Dec 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62
    1
    1. scibot 22 Dec 2023
      RRID:AB_390781

      DOI: 10.1038/s41467-023-44033-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10730909/
  19. Nov 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
    1
    1. scibot 30 Nov 2023
      RRID:AB_390781

      DOI: 10.1186/s40779-023-00494-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10675918/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma
    1
    1. scibot 15 Nov 2023
      RRID:AB_390781

      DOI: 10.7554/eLife.80625

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    ncbi.nlm.nih.gov/pmc/articles/PMC10637774/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
    2
    1. scibot 11 Nov 2023
      AB_390781

      DOI: 10.1097/BS9.0000000000000168

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      AB_390781

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    ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
  23. dx.doi.org dx.doi.org
    cwad087-html.html
    1
    1. scibot 10 Nov 2023
      RRID:AB_390781

      DOI: 10.1093/glycob/cwad087

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    dx.doi.org/10.1093/glycob/cwad087
  24. Oct 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells
    1
    1. scibot 18 Oct 2023
      RRID:AB_390781

      DOI: 10.3390/cells12192389

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    ncbi.nlm.nih.gov/pmc/articles/PMC10571842/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine
    1
    1. scibot 12 Oct 2023
      RRID: AB_390781

      DOI: 10.3892/ol.2023.14067

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    ncbi.nlm.nih.gov/pmc/articles/PMC10561147/
  27. www.cell.com www.cell.com
    15-keto-PGE2 Alleviates Nonalcoholic Steatohepatitis through its Covalent Modification of NF-κB Factors
    1
    1. scibot 06 Oct 2023
      RRID:AB_390781

      DOI: 10.1016/j.isci.2023.107997

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    cell.com/iscience/abstract/S2589-0042(23)02074-6
  28. www.sciencedirect.com www.sciencedirect.com
    ERK1-mediated immunomodulation of mesenchymal stem cells ameliorates inflammatory disorders
    1
    1. scibot 01 Oct 2023
      RRID:AB_390781

      DOI: 10.1016/j.isci.2023.107868

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    sciencedirect.com/science/article/pii/S2589004223019454
  29. Aug 2023
  30. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    1. scibot 17 Aug 2023
      RRID:AB_390781

      DOI: 10.1016/j.celrep.2023.112944

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      DOI: 10.1016/j.celrep.2023.112944

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    52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
  31. www.sciencedirect.com www.sciencedirect.com
    Hedgehog receptors exert immune-surveillance roles in the epidermis across species
    1
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      DOI: 10.1016/j.celrep.2023.112929

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    sciencedirect.com/science/article/pii/S2211124723009403
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRP1 Mediated Ferroptosis Reverses Temozolomide Resistance in Glioblastoma via Affecting LCN2/FPN1 Signaling Axis Depended on NFKB2
    1
    1. scibot 01 Aug 2023
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      DOI: 10.1016/j.isci.2023.107377

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    ncbi.nlm.nih.gov/pmc/articles/PMC10374607/
  33. Jul 2023
  34. 52.53.155.43 52.53.155.43
    NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62
    1
    1. scibot 19 Jul 2023
      RRID:AB_390781

      DOI: 10.1101/2023.06.05.543428

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    52.53.155.43/5185b06857919afc7fae38712332798a8a903a3a/2023.06.05.543428v1.full-html.html
  35. www.sciencedirect.com www.sciencedirect.com
    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
    1
    1. scibot 14 Jul 2023
      RRID:AB_390781

      DOI: 10.1016/j.ccell.2023.06.007

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    sciencedirect.com/science/article/pii/S1535610823002179
  36. Jun 2023
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion
    1
    1. scibot 30 Jun 2023
      RRID:AB_390781

      DOI: 10.3389/fimmu.2023.1189953

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    ncbi.nlm.nih.gov/pmc/articles/PMC10291184/
  38. www.sciencedirect.com www.sciencedirect.com
    Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts
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    1. scibot 29 Jun 2023
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      DOI: 10.1016/j.isci.2023.107113

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    sciencedirect.com/science/article/pii/S2589004223011902
  39. www.sciencedirect.com www.sciencedirect.com
    Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas
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      DOI: 10.1016/j.xcrm.2023.101082

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    sciencedirect.com/science/article/pii/S266637912300201X
  40. www.sciencedirect.com www.sciencedirect.com
    The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB
    1
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      DOI: 10.1016/j.celrep.2023.112586

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    sciencedirect.com/science/article/pii/S2211124723005971
  41. May 2023
  42. www.sciencedirect.com www.sciencedirect.com
    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
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    1. scibot 26 May 2023
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      DOI: 10.1016/j.ccell.2023.04.019

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    sciencedirect.com/science/article/pii/S1535610823001630
  43. www.sciencedirect.com www.sciencedirect.com
    A LY6E-PHB1-TRIM21 assembly degrades CD14 protein to mitigate LPS-induced inflammatory response
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      DOI: 10.1016/j.isci.2023.106808

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    sciencedirect.com/science/article/pii/S2589004223008854
  44. www.mdpi.com www.mdpi.com
    Lysimachiae Herba Inhibits Inflammatory Reactions and Improves Lipopolysaccharide/D-Galactosamine-Induced Hepatic Injury
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      DOI: 10.3390/antiox10091387

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    mdpi.com/2076-3921/10/9/1387/htm
  45. www.sciencedirect.com www.sciencedirect.com
    Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19
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      DOI: 10.1016/j.xcrm.2022.100680

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    sciencedirect.com/science/article/pii/S2666379122002166
  46. Apr 2023
  47. www.cell.com www.cell.com
    Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation
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      DOI: 10.1016/j.ccell.2023.03.008

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    cell.com/cancer-cell/abstract/S1535-6108(23)00081-8
  48. www.sciencedirect.com www.sciencedirect.com
    Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
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      DOI: 10.1016/j.cell.2023.02.035

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    sciencedirect.com/science/article/pii/S0092867423002131
  49. Mar 2023
  50. www.sciencedirect.com www.sciencedirect.com
    LMAN1 is a receptor for house dust mite allergens
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      DOI: 10.1016/j.celrep.2023.112208

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    sciencedirect.com/science/article/pii/S221112472300219X
  51. Feb 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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      DOI: 10.1016/j.isci.2023.106169

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    sciencedirect.com/science/article/pii/S2589004223002468
  53. Jan 2023
  54. academic.oup.com academic.oup.com
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  57. Dec 2022
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  62. Oct 2022
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  64. Aug 2022
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  67. Apr 2022
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    Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells
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  72. Feb 2022
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    MYC and MIZ1-dependent vesicular transport of double-strand RNA controls immune evasion in pancreatic ductal adenocarcinoma
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  76. Jan 2022
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    Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
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  78. Dec 2021
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  81. Nov 2021
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  83. Aug 2021
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    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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    Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response
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  91. Jul 2021
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    Regulation of the endosomal SNX27-retromer by OTULIN
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    Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma
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    Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response
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    Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase
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  101. Jun 2021
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    Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model
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  103. www.hindawi.com www.hindawi.com
    Table 2 | Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition
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    Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation
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    OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin
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    A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression
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  107. May 2021
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    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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    The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis
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    In utero inflammatory challenge induces an early activation of the hepatic innate immune response in late gestation fetal sheep - Miguel A Zarate, Stephanie R Wesolowski, Leanna M Nguyen, Robyn K De Dios, Randall B Wilkening, Paul J Rozance, Clyde J Wright,
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  141. Nov 2018
  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells
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    A Method for the Acute and Rapid Degradation of Endogenous Proteins
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  150. academic.oup.com academic.oup.com
    Exendin-4, a Glucagonlike Peptide-1 Receptor Agonist, Attenuates Breast Cancer Growth by Inhibiting NF-κB Activation
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    IL-1β Inhibits Connexin 43 and Disrupts Decidualization of Human Endometrial Stromal Cells Through ERK1/2 and p38 MAP Kinase
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  152. jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com
    Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 expression after oxygen-glucose deprivation and reoxygenation via TLR4 and NF-κB signaling in an IL-6-dependent manner
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  153. Nov 2017
  154. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protein kinase D exerts neuroprotective functions during oxidative stress via Nuclear Factor kappaB‐independent signaling pathways
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    A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN
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      RRID:AB_390781 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2451945617302805
  156. elifesciences.org elifesciences.org
    Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses
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    1. scibot 08 Nov 2017
      AB_390781

      Curator: @chewbeccax

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      (Cell Signaling Technology Cat# 4814, RRID:AB_390781)

      SciCrunch record: RRID:AB_390781

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      RRID:AB_390781 RRIDCUR:Validated
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    elifesciences.org/articles/24425
  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase
    1
    1. scibot 08 Nov 2017
      AB_390781

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 4814, RRID:AB_390781)

      SciCrunch record: RRID:AB_390781

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      RRID:AB_390781
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    ncbi.nlm.nih.gov/pmc/articles/PMC4160779/