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Opposing functions of gut immunomodulatory metabolites on CAR-T therapy

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1. scibot 01 Oct 2026
  
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  DOI: 10.1016/j.cell.2026.09.004
  
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sciencedirect.com/science/article/pii/S0092867426010731
Aug 2026
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Milk osteopontin alters the infant microbiome to drive DC hematopoiesis and disease tolerance

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  DOI: 10.1016/j.cell.2026.07.022
  
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sciencedirect.com/science/article/pii/S0092867426008202
Jul 2026
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An IGF2BP3-dependent metabolic circuit governs macrophage recruitment and immunosuppression in glioblastoma

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1. scibot 06 Jul 2026
  
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  DOI: 10.1016/j.celrep.2026.117643
  
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sciencedirect.com/science/article/pii/S2211124726007217
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Targeting p21-High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

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1. scibot 03 Jul 2026
  
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  DOI: 10.1002/advs.76384
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76384
Jun 2026
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Genetic ablation of Sfxn5 induces mitochondrial dysfunction and precipitates lethal metabolic crisis in mice

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1. scibot 24 Jun 2026
  
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  DOI: 10.1016/j.isci.2026.116468
  
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sciencedirect.com/science/article/pii/S2589004226018432
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Triple-armed oncolytic HSV enhances antitumor immunity by remodeling the tumor microenvironment in subcutaneous murine CRC

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  DOI: 10.1016/j.isci.2026.115883
  
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sciencedirect.com/science/article/pii/S2589004226012587
Mar 2026
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Sym024 interacts with a unique epitope on the CD73 homodimer, favoring effective bivalent binding to improve anti-PD1 therapy

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1. scibot 04 Mar 2026
  
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  DOI: 10.1158/1078-0432.CCR-25-2406
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12950896/
Feb 2026
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Efficacy and safety of autologous CD5-KO anti-CD5 CAR-T cells in relapsed/refractory CD5+ hematological malignancies

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1. scibot 03 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2026.102584
  
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Jan 2026
journals.asm.org journals.asm.org

Synergistic effects of Clostridium butyricum and Akkermansia muciniphila-derived postbiotics ameliorate DSS-induced colitis and associated tumorigenesis through immunomodulation and microbiota regulation in mice

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1. scibot 06 Jan 2026
  
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  DOI: 10.1128/msystems.00689-25
  
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journals.asm.org/doi/10.1128/msystems.00689-25
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Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116840
  
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sciencedirect.com/science/article/pii/S2211124725016122
Oct 2025
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A single-dose nanoparticle vaccine protects against mpox in preclinical models

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116358
  
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sciencedirect.com/science/article/pii/S2211124725011295
Sep 2025
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DDX3X mutation and Epstein-Barr virus cooperate to induce R-loop-dependent oncogenesis

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  DOI: 10.1016/j.celrep.2025.116237
  
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sciencedirect.com/science/article/pii/S2211124725010083
Aug 2025
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Identification and validation of intratumoral microbiome associated with sensitization to immune checkpoint inhibitors

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1. scibot 27 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102306
  
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sciencedirect.com/science/article/pii/S2666379125003799
Jul 2025
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Temporally programmed STING nanoadjuvant delivery unlocks synergistic chemotherapy-induced antitumor immunity

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1. scibot 22 Jul 2025
  
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  DOI: 10.1126/sciadv.adw0797
  
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science.org/doi/10.1126/sciadv.adw0797
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Temporally programmed STING nanoadjuvant delivery unlocks synergistic chemotherapy-induced antitumor immunity

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1. scibot 22 Jul 2025
  
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  DOI: 10.1126/sciadv.adw0797
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12273768/
Jun 2025
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Gut microbiota dysbiosis induced by brain tumors modulates the efficacy of immunotherapy

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115825
  
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sciencedirect.com/science/article/pii/S2211124725005960
May 2025
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PIM kinase control of CD8 T cell protein synthesis and cell trafficking

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.98622
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12074636/
Mar 2025
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DA-DRD5 signaling reprograms B cells to promote CD8+ T cell-mediated antitumor immunity

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115364
  
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sciencedirect.com/science/article/pii/S2211124725001354
Feb 2025
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The combination of Clostridium butyricum and Akkermansia muciniphila mitigates DSS-induced colitis and attenuates colitis-associated tumorigenesis by modulating gut microbiota and reducing CD8+ T cells in mice

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1. scibot 20 Feb 2025
  
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  DOI: 10.1128/msystems.01567-24
  
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sciencedirect.com/org/science/article/pii/S2379507725000066
Aug 2024
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High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases

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1. scibot 21 Aug 2024
  
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Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity

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1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.immuni.2024.07.010
  
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May 2024
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Polyvalent mpox mRNA vaccines elicit robust immune responses and confer potent protection against vaccinia virus

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1. scibot 30 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114269
  
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Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity

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1. scibot 14 May 2024
  
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  DOI: 10.1016/j.xcrm.2024.101533
  
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SZPMYTH_PERERA_DILHAN_2024_THESIS_J244231748-j148097451-html.html

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1. scibot 09 May 2024
  
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  DOI: 10.3389/fimmu.2021.711650
  
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52.53.155.43/2afb981b275f240c20941e1ba23a705a0f60db9b/SZPMYTH_PERERA_DILHAN_2024_THESIS_J244231748-j148097451-html.html
Mar 2024
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Oncolytic bacteria VNP20009 expressing IFNβ inhibits melanoma progression by remodeling the tumor microenvironment

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1. scibot 22 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109372
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10951989/
Feb 2024
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Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment

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  DOI: 10.1016/j.celrep.2024.113797
  
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Nov 2023
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Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine

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  DOI: 10.7150/thno.85106
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10614673/
Aug 2023
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IL-24 is the key effector of Th9 cell-mediated tumor immunotherapy

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1. scibot 12 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107531
  
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52.53.155.43/177943f7d2a1e7d0acb51004d129b2330d72300b/PIIS2589004223016085-html.html
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The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR+ CD8+ effector state, and its deletion improves checkpoint blockade

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  DOI: 10.1016/j.celrep.2023.112905
  
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Jul 2023
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QUAS-R: An SLC1A5-mediated glutamine uptake assay with single-cell resolution reveals metabolic heterogeneity with immune populations

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1. scibot 21 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112828
  
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May 2023
jnm.snmjournals.org jnm.snmjournals.org

Targeted α-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment

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1. scibot 12 May 2023
  
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  DOI: 10.2967/jnumed.122.264752
  
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jnm.snmjournals.org/content/64/5/751
Apr 2023
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Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging

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  DOI: 10.1016/j.stem.2023.03.016
  
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sciencedirect.com/science/article/pii/S1934590923000875
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Niche-expressed Galectin-1 is involved in pre-B acute lymphoblastic leukemia relapse through pre-BCR activation

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1. scibot 05 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106385
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10060685/
Mar 2023
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Pre-existing immunity modulates responses to mRNA boosters

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1. scibot 04 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112167
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9928730/
Feb 2023
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XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections

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1. scibot 16 Feb 2023
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.celrep.2023.112123
  
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Jan 2023
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GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology

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1. scibot 12 Jan 2023
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.immuni.2022.12.009
  
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Aug 2022
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Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation

1
1. scibot 17 Aug 2022
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.celrep.2022.111205
  
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May 2022
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A low dose adenovirus vectored vaccine expressing Schistosoma mansoni Cathepsin B protects from intestinal schistosomiasis in mice

1
1. scibot 04 May 2022
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.ebiom.2022.104036
  
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Apr 2022
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Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse

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1. scibot 27 Apr 2022
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.celrep.2022.110747
  
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Mar 2022
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The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer

1
1. scibot 15 Mar 2022
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.cmet.2022.02.010
  
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Feb 2022
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Protocol to identify and monitor key mutations of broadly neutralizing antibody lineages following sequential immunization of Ig-humanized mice

1
1. scibot 23 Feb 2022
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.xpro.2022.101180
  
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PD-1 blockade therapy promotes infiltration of tumor-attacking exhausted T cell clonotypes

1
1. scibot 02 Feb 2022
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.celrep.2022.110331
  
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sciencedirect.com/science/article/pii/S221112472200047X
Nov 2021
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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

1
1. scibot 03 Nov 2021
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.celrep.2021.109911
  
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Aug 2021
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Expression of Bioactive Chemerin by Keratinocytes Inhibits Late Stages of Tumor Development in a Chemical Model of Skin Carcinogenesis

1
1. scibot 01 Aug 2021
  
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  RRID:AB_394081
  
  DOI: 10.3389/fonc.2019.01253
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6873210/
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ISRE-Reporter Mouse Reveals High Basal and Induced Type I IFN Responses in Inflammatory Monocytes

1
1. scibot 01 Aug 2021
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.celrep.2018.11.030
  
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May 2021
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Pre-clinical evaluation of a whole-parasite vaccine to control human babesiosis

1
1. scibot 14 May 2021
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.chom.2021.04.008
  
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A vaccine inducing solely cytotoxic T lymphocytes fully prevents Zika virus infection and fetal damage

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1. scibot 12 May 2021
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.celrep.2021.109107
  
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Apr 2021
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MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23

1
1. scibot 26 Apr 2021
  
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  DOI: 10.1016/j.immuni.2021.02.015
  
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Mar 2021
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Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth

1
1. scibot 01 Mar 2021
  
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  DOI: 10.1016/j.immuni.2020.12.014
  
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Feb 2021
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Activation of M1 Macrophages in Response to Recombinant TB Vaccines With Enhanced Antimycobacterial Activity

1
1. scibot 25 Feb 2021
  
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  RRID:AB_394081
  
  DOI: 10.3389/fimmu.2020.01298
  
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Machine Learning of Hematopoietic Stem Cell Divisions from Paired Daughter Cell Expression Profiles Reveals Effects of Aging on Self-Renewal

1
1. scibot 24 Feb 2021
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.cels.2020.11.004
  
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cell.com/cell-systems/abstract/S2405-4712(20)30455-5
Sep 2020
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Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

1
1. scibot 15 Sep 2020
  
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  RRID:AB_394081
  
  DOI: 10.7554/eLife.53725
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7056270/
Jan 2020
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Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging

1
1. scibot 13 Jan 2020
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.celrep.2019.05.045
  
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The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells

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1. scibot 13 Jan 2020
  
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  RRID:AB_394081
  
  DOI: 10.1016/j.celrep.2019.11.089
  
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Nov 2018
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Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies

1
1. scibot 05 Nov 2018
  
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Nov 2017
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A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45

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1. scibot 08 Nov 2017
  
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