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A type I interferon-mitochondrial axis regulates efferocytosis and interferon-stimulated gene induction in macrophages

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1. scibot 29 Jan 2026
  
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  DOI: 10.1016/j.immuni.2025.12.010
  
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sciencedirect.com/science/article/pii/S1074761325005667
Jan 2026
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Discovery, delineation, and therapeutic targeting of a hyper-translation pathway driving cytokine release syndrome

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102531
  
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sciencedirect.com/science/article/pii/S2666379125006044
Jul 2025
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Sca-1 expression depicts pro-inflammatory murine neutrophils under steady-state and pathological conditions

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115995
  
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sciencedirect.com/science/article/pii/S2211124725007661
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Activated T Cells Break Tumor Immunosuppression by Macrophage Reeducation

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1. scibot 08 Jul 2025
  
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  DOI: 10.1158/2159-8290.CD-24-0415
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12223510/
Jun 2025
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Chalkophore-mediated respiratory oxidase flexibility controls M. tuberculosis virulence

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1. scibot 12 Jun 2025
  
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  DOI: 10.7554/eLife.105794
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12140626/
May 2025
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1-s2.0-S2589004225009368-main-html.html

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112675
  
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52.53.155.43/4bd6a68fbeb8de6c2d0efadcd6e514f5c1b2156f/1-s2.0-S2589004225009368-main-html.html
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Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.04.007
  
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sciencedirect.com/science/article/pii/S1535610825001667
Apr 2025
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Chalkophore mediated respiratory oxidase flexibility controls M. tuberculosis virulence

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1. scibot 19 Apr 2025
  
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  DOI: 10.7554/eLife.105794.2
  
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elifesciences.org/reviewed-preprints/105794
Jan 2025
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A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis

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1. scibot 30 Jan 2025
  
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  DOI: 10.1016/j.immuni.2025.01.003
  
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sciencedirect.com/science/article/pii/S1074761325000263
Dec 2024
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Durable lymphocyte subset elimination upon a single dose of AAV-delivered depletion antibody dissects immune control of chronic viral infection

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1. scibot 24 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.021
  
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sciencedirect.com/science/article/pii/S1074761324005363
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Post-translational toxin modification by lactate controls Staphylococcus aureus virulence

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1. scibot 21 Dec 2024
  
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  DOI: 10.1038/s41467-024-53979-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11561239/
Nov 2024
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Meningeal neutrophil immune signaling influences behavioral adaptation following threat

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1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.neuron.2024.10.018
  
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sciencedirect.com/science/article/pii/S0896627324007669
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Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.008
  
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sciencedirect.com/science/article/pii/S1535610824003969
Oct 2024
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A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis

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1. scibot 04 Oct 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-3257
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11443216/
Aug 2024
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A hepatocyte-specific transcriptional program driven by Rela and Stat3 exacerbates experimental colitis in mice by modulating bile synthesis

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1. scibot 22 Aug 2024
  
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  DOI: 10.7554/eLife.93273
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11321761/
Jun 2024
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Reactive oxygen species regulation by NCF1 governs ferroptosis susceptibility of Kupffer cells to MASH

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.cmet.2024.05.008
  
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sciencedirect.com/science/article/pii/S1550413124001840
May 2024
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Chalkophore mediated respiratory oxidase flexibility controls M. tuberculosis virulence

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1. scibot 01 May 2024
  
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  RRID:AB_394208
  
  DOI: 10.1101/2024.04.12.589290
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11030325/
Apr 2024
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The trogocytosis of neutrophils on initial transplanted tumor in mice

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1. scibot 24 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109661
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11033691/
Mar 2024
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Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers

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1. scibot 15 Mar 2024
  
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  DOI: 10.1016/j.ccell.2024.02.013
  
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sciencedirect.com/science/article/pii/S1535610824000576
Jan 2024
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Bone marrow monocytes sustain NK cell-poiesis during non-alcoholic steatohepatitis

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1. scibot 18 Jan 2024
  
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  DOI: 10.1016/j.celrep.2024.113676
  
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sciencedirect.com/science/article/pii/S2211124724000044
Nov 2023
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Investigating the role of platelets and platelet-derived transforming growth factor-β in idiopathic pulmonary fibrosis

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1. scibot 15 Nov 2023
  
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  DOI: 10.1152/ajplung.00227.2022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10639018/
Oct 2023
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Biomimetic superabsorbent hydrogel acts as a gut protective dynamic exoskeleton improving metabolic parameters and expanding A. muciniphila

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1. scibot 26 Oct 2023
  
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  DOI: 10.1016/j.xcrm.2023.101235
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10591066/
Aug 2023
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CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation

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1. scibot 26 Aug 2023
  
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  DOI: 10.7554/eLife.84752
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10431918/
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Down Syndrome is Associated with Altered Frequency and Functioning of Tracheal Multiciliated Cells, and Response to Influenza Virus Infection

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1. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107361
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10405068/
Jul 2023
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Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy

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1. scibot 14 Jul 2023
  
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  DOI: 10.1038/s41467-023-39759-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10336067/
Jun 2023
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Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner

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1. scibot 22 Jun 2023
  
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  DOI: 10.1016/j.molcel.2023.05.035
  
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sciencedirect.com/science/article/pii/S1097276523004197
May 2023
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A hypometabolic defense strategy against malaria

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.cmet.2022.06.011
  
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sciencedirect.com/science/article/pii/S1550413122002315
Apr 2023
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A preclinical randomized controlled multi-centre trial of anti-interleukin-17A treatment for acute ischaemic stroke

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1. scibot 14 Apr 2023
  
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  DOI: 10.1093/braincomms/fcad090
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10088471/
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T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants

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  DOI: 10.1016/j.cell.2023.03.007
  
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sciencedirect.com/science/article/pii/S0092867423002258
Mar 2023
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Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection

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  DOI: 10.1002/cti2.1443
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10034483/
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Controlled release of enhanced cross-hybrid IgGA Fc PD-L1 inhibitors using oncolytic adenoviruses

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  DOI: 10.1016/j.omto.2023.01.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9995465/
Feb 2023
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Oxidative phosphorylation selectively orchestrates tissue macrophage homeostasis

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  DOI: 10.1016/j.immuni.2023.01.011
  
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sciencedirect.com/science/article/pii/S1074761323000213
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Whole-mount immunofluorescence imaging and isolation of mesothelium-bound immune cell aggregates during mouse peritoneal inflammation

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  DOI: 10.1016/j.xpro.2023.102079
  
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sciencedirect.com/science/article/pii/S2666166723000370
Dec 2022
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Klebsiella pneumoniae induces inflammatory bowel disease through caspase-11-mediated IL-18 in the gut epithelial cells

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1. scibot 22 Dec 2022
  
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  DOI: 10.1016/j.jcmgh.2022.11.005
  
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cmghjournal.org/article/S2352-345X(22)00238-7/abstract
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IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer

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1. scibot 17 Dec 2022
  
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  DOI: 10.1016/j.ccell.2022.11.014
  
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sciencedirect.com/science/article/pii/S153561082200561X
Nov 2022
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DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability

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1. scibot 23 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111703
  
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sciencedirect.com/science/article/pii/S2211124722015777
Sep 2022
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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

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Myeloid Wls expression is dispensable for skin wound healing and blood vessel regeneration

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Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal

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PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity

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B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema

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Tetraspanin CD82 restrains phagocyte migration but supports macrophage activation

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Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche

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Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections

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Galectin-9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin-dependent manner

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Tumor-derived extracellular vesicles regulate tumor-infiltrating regulatory T cells via the inhibitory immunoreceptor CD300a

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TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis

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Oct 2021
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Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity

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Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-derived tumor organoids

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Untitled document

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Expansion of CD10neg neutrophils and CD14+HLA-DRneg/low monocytes driving proinflammatory responses in patients with acute myocardial infarction

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Expression of Bioactive Chemerin by Keratinocytes Inhibits Late Stages of Tumor Development in a Chemical Model of Skin Carcinogenesis

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Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche

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A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves

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Cytomegalovirus subverts macrophage identity

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Differential usage of transcriptional repressor Zeb2 enhancers distinguishes adult and embryonic hematopoiesis

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Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver

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Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment

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Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3+ Regulatory T Cells via a miR-342-Dependent Mechanism

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Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP

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Functional characterization of the dural sinuses as a neuroimmune interface

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Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain

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Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity

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ncbi.nlm.nih.gov/pmc/articles/PMC6382412/
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Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism

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Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans

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Tumor-Promoting Ly-6G+ SiglecFhigh Cells Are Mature and Long-Lived Neutrophils

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Multicolor two-photon imaging of in vivo cellular pathophysiology upon influenza virus infection using the two-photon IMPRESS

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Targeting Interleukin-1β Protects from Aortic Aneurysms Induced by Disrupted Transforming Growth Factor β Signaling

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cell.com/immunity/abstract/S1074-7613(17)30471-5
Jan 2020
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Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

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Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response

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Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge

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Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation

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Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species

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c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells

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Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC

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LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance

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The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages

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Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy

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Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis

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Gut Microbes Egested during Bites of Infected Sand Flies Augment Severity of Leishmaniasis via Inflammasome-Derived IL-1β

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Staphylococcus aureus Epicutaneous Exposure Drives Skin Inflammation via IL-36-Mediated T Cell Responses

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Targeting Interleukin-1β Protects from Aortic Aneurysms Induced by Disrupted Transforming Growth Factor β Signaling

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Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction

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