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Pseudouridine synthase 1-targeted therapy activates antiviral immunity to boost cancer immunotherapy

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  DOI: 10.1016/j.celrep.2025.116233
  
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sciencedirect.com/science/article/pii/S2211124725010046
Aug 2025
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Sympathetic innervation maintains the murine quiescent skeletal muscle stem cell pool via perivascular-derived Angpt1

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  DOI: 10.1016/j.devcel.2025.07.006
  
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sciencedirect.com/science/article/pii/S1534580725004447
Jul 2025
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Deconstructing the intercellular interactome in vascular dementia with focal ischemia for therapeutic applications

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1. scibot 01 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.06.002
  
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cell.com/cell/fulltext/S0092-8674(25)00636-1
Jun 2025
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Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.jpet.2025.103634
  
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sciencedirect.com/science/article/pii/S0022356525398472
Apr 2025
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Somatic Miwi2 modulates mitochondrial function in airway multiciliated cells and exacerbates influenza pathogenesis

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1. scibot 09 Apr 2025
  
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  DOI: 10.1016/j.isci.2025.112291
  
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sciencedirect.com/science/article/pii/S2589004225005528
Jan 2025
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Protocol to detect neutral lipids with BODIPY staining in myeloid-derived suppressor cells in mouse mammary tumors

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1. scibot 07 Jan 2025
  
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  DOI: 10.1016/j.xpro.2024.103485
  
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sciencedirect.com/science/article/pii/S2666166724006506
Dec 2024
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Single-nucleus transcriptomics reveal the differentiation trajectories of periosteal skeletal/stem progenitor cells in bone regeneration

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1. scibot 11 Dec 2024
  
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  DOI: 10.7554/eLife.92519
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11623931/
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Fatty Acid Derivatization and Cyclization of the Immunomodulatory Peptide RP-182 Targeting CD206high Macrophages Improve Antitumor Activity

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1. scibot 11 Dec 2024
  
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  DOI: 10.1158/1535-7163.MCT-23-0790
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11612619/
Nov 2024
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Tumor stage-driven disruption of NK cell maturation in human and murine tumors

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1. scibot 26 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111233
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11585790/
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Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.008
  
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sciencedirect.com/science/article/pii/S1535610824003969
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Local adaptive immunity in atherosclerosis with T cell activation by aortic DCs accelerates pathogenesis

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1. scibot 08 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111144
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11536043/
Sep 2024
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Microglia Suppress Ascl1-Induced Retinal Regeneration in Mice

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.celrep.2020.108507
  
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sciencedirect.com/science/article/pii/S2211124720314960
Jul 2024
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Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors

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1. scibot 18 Jul 2024
  
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  AB_394489
  
  DOI: 10.1016/j.cell.2024.06.013
  
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sciencedirect.com/science/article/pii/S0092867424006536
Apr 2024
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Extracellular signal‐regulated kinase regulates microglial immune responses in Alzheimer’s disease

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1. scibot 05 Apr 2024
  
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  DOI: 10.1002/jnr.24829
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24829
Mar 2024
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ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer

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1. scibot 22 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109366
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10951988/
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Oncolytic bacteria VNP20009 expressing IFNβ inhibits melanoma progression by remodeling the tumor microenvironment

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1. scibot 22 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109372
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10951989/
Jan 2024
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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

2
1. scibot 04 Jan 2024
  
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  DOI: 10.1016/j.devcel.2023.07.025
  
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2. scibot 04 Jan 2024
  
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  RRID:AB_394489
  
  DOI: 10.1016/j.devcel.2023.07.025
  
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sciencedirect.com/science/article/pii/S1534580723003945
Nov 2023
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Airway epithelial cells and macrophages trigger IL-6-CD95/CD95L axis and mediate initial immunopathology of COVID-19

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1. scibot 29 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108366
  
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sciencedirect.com/science/article/pii/S2589004223024434
Oct 2023
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Adipocyte Subpopulations Mediate Growth Hormone-induced Lipolysis and Glucose Tolerance in Male Mice

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1. scibot 31 Oct 2023
  
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  DOI: 10.1210/endocr/bqad151
  
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academic.oup.com/endo/article-abstract/164/11/bqad151/7332055
Aug 2023
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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

1
1. scibot 25 Aug 2023
  
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  DOI: 10.1016/j.devcel.2023.07.025
  
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sciencedirect.com/science/article/pii/S1534580723003945
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Enhanced glycolysis-mediated energy production in alveolar stem cells is required for alveolar regeneration

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  DOI: 10.1016/j.stem.2023.07.007
  
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sciencedirect.com/science/article/pii/S1934590923002539
Jul 2023
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Differentiation latency and dormancy signatures define fetal liver HSCs at single cell resolution

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1. scibot 04 Jul 2023
  
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  DOI: 10.1101/2023.06.01.543314
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10274697/
Jun 2023
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Generation of liver mesenchyme and ductal cell organoid co-culture using cell self-aggregation and droplet microfluidics

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1. scibot 07 Jun 2023
  
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  DOI: 10.1016/j.xpro.2023.102333
  
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sciencedirect.com/science/article/pii/S2666166723003003
May 2023
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Tumor propagating side population cells are a dynamic subpopulation in undifferentiated pleomorphic sarcoma

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1. scibot 06 May 2023
  
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  DOI: 10.1172/jci.insight.148768
  
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insight.jci.org/articles/view/148768
Mar 2023
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HSC-independent definitive hematopoiesis persists into adult life

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1. scibot 16 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112239
  
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sciencedirect.com/science/article/pii/S2211124723002504
Feb 2023
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Infection induces tissue-resident memory NK cells that safeguard tissue health

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1. scibot 15 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.016
  
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sciencedirect.com/science/article/pii/S1074761323000262
Jan 2023
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Specialized functions and sexual dimorphism explain the functional diversity of the myeloid populations during glioma progression

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1. scibot 12 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111971
  
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sciencedirect.com/science/article/pii/S2211124722018757
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Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance

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  DOI: 10.1016/j.ccell.2022.12.003
  
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cell.com/cancer-cell/fulltext/S1535-6108(22)00589-X
Dec 2022
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Embryogenic stem cell-derived intestinal crypt fission directs de novo crypt genesis

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  DOI: 10.1016/j.celrep.2022.111796
  
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sciencedirect.com/science/article/pii/S2211124722016849
Nov 2022
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Uncovering the emergence of HSCs in the human fetal bone marrow by single-cell RNA-seq analysis

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1. scibot 04 Nov 2022
  
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  DOI: 10.1016/j.stem.2022.10.005
  
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sciencedirect.com/science/article/pii/S1934590922004234
Jan 2022
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Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions

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1. scibot 16 Jan 2022
  
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  DOI: 10.1016/j.crmeth.2021.100153
  
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sciencedirect.com/science/article/pii/S2667237521002307
Aug 2021
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Skeletal Muscle Stem Cells from PSC-Derived Teratomas Have Functional Regenerative Capacity

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1. scibot 06 Aug 2021
  
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  RRID:AB_394489
  
  DOI: 10.1016/j.stem.2018.06.010
  
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sciencedirect.com/science/article/pii/S1934590918302923
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Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation

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1. scibot 03 Aug 2021
  
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  DOI: 10.1016/j.stem.2021.07.002
  
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sciencedirect.com/science/article/pii/S1934590921002873
Jul 2021
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PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress

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1. scibot 31 Jul 2021
  
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  RRID:AB_394489
  
  DOI: 10.1016/j.stem.2019.03.019
  
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  Curator: @ethanbadger
  
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  RRID:AB_394489 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1934590919301183
Jun 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted murine heart

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1. scibot 26 Jun 2021
  
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  RRID:AB_394489
  
  DOI: 10.7554/eLife.65921
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8216715/
May 2021
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Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets

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1. scibot 09 May 2021
  
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  RRID:AB_394489
  
  DOI: 10.1016/j.stem.2021.01.011
  
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sciencedirect.com/science/article/pii/S1934590921000114
Apr 2021
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Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging

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1. scibot 13 Apr 2021
  
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  RRID:AB_394489
  
  DOI: 10.1016/j.stem.2021.03.017
  
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sciencedirect.com/science/article/pii/S1934590921001235
Mar 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Extracellular signal‐regulated kinase regulates microglial immune responses in Alzheimer’s disease

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1. scibot 24 Mar 2021
  
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  RRID:AB_394489
  
  DOI: 10.1002/jnr.24829
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24829
Dec 2020
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The Master Regulator Protein BAZ2B Can Reprogram Human Hematopoietic Lineage-Committed Progenitors into a Multipotent State

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1. scibot 13 Dec 2020
  
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  RRID:AB_394489
  
  DOI: 10.1016/j.celrep.2020.108474
  
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sciencedirect.com/science/article/pii/S2211124720314637
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction

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1. scibot 26 Sep 2020
  
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  RRID:AB_394489
  
  DOI: 10.15252/embj.2020104464
  
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Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells

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1. scibot 13 Sep 2020
  
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  RRID:AB_394489
  
  DOI: 10.1016/j.celrep.2020.107688
  
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Impaired phagocytic function in CX3CR1+ tissue‐resident skeletal muscle macrophages prevents muscle recovery after influenza A virus‐induced pneumonia in old mice

1
1. scibot 04 Sep 2020
  
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  CD45 clone 30‐F11 PE‐Cy7
  
  DOI: 10.1111/acel.13180
  
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Progesterone Receptor Serves the Ovary as a Trigger of Ovulation and a Terminator of Inflammation

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1. scibot 04 Sep 2020
  
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  RRID:AB_394489
  
  DOI: 10.1016/j.celrep.2020.03.060
  
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sciencedirect.com/science/article/pii/S2211124720303855
Jan 2020
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Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_394489
  
  DOI: 10.1016/j.stem.2019.08.007
  
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Estrogen Regulates the Satellite Cell Compartment in Females

1
1. scibot 13 Jan 2020
  
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  RRID:AB_394489
  
  DOI: 10.1016/j.celrep.2019.06.025
  
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The Release of Adipose Stromal Cells from Subcutaneous Adipose Tissue Regulates Ectopic Intramuscular Adipocyte Deposition

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1. scibot 13 Jan 2020
  
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  RRID:AB_394489
  
  DOI: 10.1016/j.celrep.2019.03.038
  
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PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress

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  RRID:AB_394489
  
  DOI: 10.1016/j.stem.2019.03.019
  
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sciencedirect.com/science/article/pii/S1934590919301183
Nov 2018
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TRPV4 Channel Signaling in Macrophages Promotes Gastrointestinal Motility via Direct Effects on Smooth Muscle Cells

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1074761318301900
Nov 2017
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Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia

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1. scibot 08 Nov 2017
  
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  AB_394489
  
  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S0896627317305184