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Controlled pyroptosis of engineered macrophages enables biphasic antitumor via the release of oncolytic bacteria and inflammatory signals

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1. scibot 30 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116918
  
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sciencedirect.com/science/article/pii/S2211124725016900
Dec 2025
54.241.53.176 54.241.53.176

A K27-linked Ubiquitin Checkpoint Controls NOTCH Homeostasis

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1. scibot 23 Dec 2025
  
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  DOI: 10.64898/2025.12.18.695023
  
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54.241.53.176/4017c0bf441a0c93b25bb7d3207bac083a93d59a/2025.12.18.695023v1.full-html.html
Nov 2025
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Fluorinated prodrug-engineered nano-remodeler relieves tumor hypoxia for dual-enhanced ferroptosis-immunotherapy

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1. scibot 13 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102427
  
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sciencedirect.com/science/article/pii/S2666379125005002
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Glucocorticoids unleash immune-dependent melanoma control through inhibition of the GARP/TGF-β axis

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1. scibot 25 Oct 2025
  
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  DOI: 10.1158/2159-8290.CD-24-1224
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618275/
May 2025
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The role of Tim-3+T cell subsets in the peripheral blood of patients with COVID-19 and diabetes

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112339
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12053769/
Jun 2024
www.cell.com www.cell.com

Moderate-intensity aerobic exercise training improves CD8+ tumor-infiltrating lymphocytes effector function by reducing mitochondrial loss.

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1. scibot 30 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110121
  
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cell.com/iscience/abstract/S2589-0042(24)01346-4
Mar 2024
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A tetravalent nanovaccine that inhibits growth of HPV-associated head and neck carcinoma via dendritic and T cell activation

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1. scibot 27 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109439
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10957412/
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ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer

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1. scibot 22 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109366
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10951988/
Jun 2023
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Virion glycosylation influences mycobacteriophage immune recognition

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.chom.2023.05.028
  
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sciencedirect.com/science/article/pii/S1931312823002214
Apr 2023
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Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup

1
1. scibot 07 Apr 2023
  
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  DOI: 10.1016/j.immuni.2023.03.008
  
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sciencedirect.com/science/article/pii/S1074761323001280
Mar 2023
europepmc.org europepmc.org

mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy

1
1. scibot 22 Mar 2023
  
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  DOI: 10.1016/j.xcrm.2023.100978
  
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europepmc.org/article/med/36933554
Feb 2023
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XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections

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1. scibot 16 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112123
  
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sciencedirect.com/science/article/pii/S2211124723001341
Jan 2023
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CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy

1
1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111874
  
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sciencedirect.com/science/article/pii/S2211124722017703
Sep 2022
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Protocol to isolate and enrich mouse splenic naive CD4+ T cells for in vitro CD4+CD8αα+ cell induction

1
1. scibot 28 Sep 2022
  
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  DOI: 10.1016/j.xpro.2022.101728
  
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sciencedirect.com/science/article/pii/S2666166722006086
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Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis

1
1. scibot 15 Sep 2022
  
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  DOI: 10.1016/j.celrep.2022.111328
  
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sciencedirect.com/science/article/pii/S2211124722011561
Aug 2022
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Protocol for isolation and characterization of lung tissue resident memory T cells and airway trained innate immunity after intranasal vaccination in mice

1
1. scibot 30 Aug 2022
  
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  DOI: 10.1016/j.xpro.2022.101652
  
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sciencedirect.com/science/article/pii/S2666166722005329
Jun 2022
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Intestinal inflammation alters the antigen-specific immune response to a skin commensal

1
1. scibot 03 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110891
  
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sciencedirect.com/science/article/pii/S2211124722006660
May 2022
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Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut

1
1. scibot 11 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110773
  
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sciencedirect.com/science/article/pii/S221112472200537X
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes

1
1. scibot 23 Mar 2022
  
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  DOI: 10.1016/j.isci.2022.104021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8933710/
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Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2

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1. scibot 04 Mar 2022
  
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  DOI: 10.1016/j.cell.2022.02.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8825346/
Dec 2021
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Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice

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1. scibot 28 Dec 2021
  
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  DOI: 10.1016/j.xcrm.2021.100455
  
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sciencedirect.com/science/article/pii/S2666379121003232
Nov 2021
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Isolation and enrichment of mouse splenic T cells for ex vivo and in vivo T cell receptor stimulation assays

1
1. scibot 17 Nov 2021
  
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  DOI: 10.1016/j.xpro.2021.100961
  
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sciencedirect.com/science/article/pii/S2666166721006675
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Original research: CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell

1
1. scibot 18 Sep 2021
  
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  DOI: 10.1136/jitc-2021-003100
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8407215/
Jul 2021
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Untitled document

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1. scibot 31 Jul 2021
  
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  DOI: 10.1016/j.immuni.2019.01.006
  
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sciencedirect.com/science/article/pii/S1074761319300299
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JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells

2
1. scibot 27 Jul 2021
  
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  DOI: 10.1016/j.ccell.2018.10.008
  
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2. scibot 27 Jul 2021
  
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  552877
  
  DOI: 10.1016/j.ccell.2018.10.008
  
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sciencedirect.com/science/article/pii/S1535610818304744
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MYC deficiency impairs the development of effector/memory T lymphocytes

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1. scibot 07 Jul 2021
  
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  DOI: 10.1016/j.isci.2021.102761
  
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sciencedirect.com/science/article/pii/S258900422100729X
Jun 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses

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1. scibot 18 Jun 2021
  
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  DOI: 10.1016/j.isci.2021.102548
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8184506/
May 2021
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High Amount of Transcription Factor IRF8 Engages AP1-IRF Composite Elements in Enhancers to Direct Type 1 Conventional Dendritic Cell Identity

1
1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.07.018
  
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sciencedirect.com/science/article/pii/S1074761320303253
Apr 2021
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Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP

1
1. scibot 01 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.108919
  
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sciencedirect.com/science/article/pii/S2211124721002333
Sep 2020
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Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma

1
1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.ccell.2020.03.016
  
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sciencedirect.com/science/article/pii/S1535610820301562
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Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity

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1. scibot 14 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107905
  
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sciencedirect.com/science/article/pii/S221112472030886X
www.cell.com www.cell.com

Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade

1
1. scibot 03 Sep 2020
  
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  DOI: 10.1016/j.immuni.2019.01.006
  
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cell.com/immunity/abstract/S1074-7613(19)30029-9
Jan 2020
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Hematopoietic Stem Cell Transplantation Restores Naïve T-Cell Populations in Atm-Deficient Mice and in Preemptively Treated Patients With Ataxia-Telangiectasia

1
1. scibot 13 Jan 2020
  
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  DOI: 10.3389/fimmu.2019.02785
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6892974/
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Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria

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1. scibot 13 Jan 2020
  
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  RRID:AB_394506
  
  DOI: 10.1016/j.chom.2019.10.007
  
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sciencedirect.com/science/article/pii/S1931312819305311
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1. scibot 13 Jan 2020
  
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  RRID:AB_394506
  
  DOI: 10.1016/j.stem.2018.12.003
  
  Resource: (BD Biosciences Cat# 552877, RRID:AB_394506)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1934590918305939
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1. scibot 13 Jan 2020
  
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  RRID:AB_394506
  
  DOI: 10.1016/j.immuni.2019.01.006
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1074761319300299
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1. scibot 13 Jan 2020
  
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  RRID:AB_394506
  
  DOI: 10.1016/j.celrep.2018.11.083
  
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  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S2211124718318746
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Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation

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1. scibot 13 Jan 2020
  
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  AB_394506
  
  DOI: 10.1016/j.ccell.2019.04.003
  
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sciencedirect.com/science/article/pii/S1535610819301989
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c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells

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  RRID:AB_394506
  
  DOI: 10.1016/j.celrep.2019.04.090
  
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sciencedirect.com/science/article/pii/S2211124719305704
Nov 2018
europepmc.org europepmc.org

Is Receptor-Interacting Protein Kinase 3 a Viable Therapeutic Target for Mycobacterium tuberculosis Infection?

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1. scibot 05 Nov 2018
  
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  RRID:AB_394506
  
  Curator: @evieth
  
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europepmc.org/articles/PMC5985376/
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1. scibot 05 Nov 2018
  
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frontiersin.org/article/10.3389/fimmu.2018.01178/full
Nov 2017
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Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments

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1. scibot 08 Nov 2017
  
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  PE-Cy7 Rat Anti-Mouse CD8a
  
  Curator: @kaitlinsung
  
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sciencedirect.com/science/article/pii/S1550413116306519