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Targeting TMED4 enhances CD8+ T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis

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  DOI: 10.1126/sciadv.aee0517
  
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science.org/doi/10.1126/sciadv.aee0517
Feb 2026
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Sensory neuron production of substance P and TAFA4 promotes disease tolerance during viral infection

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.022
  
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sciencedirect.com/science/article/pii/S1074761326000439
Nov 2025
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Trilaciclib triggers a neutrophil-related immune response and sensitizes non-small cell lung cancer to anti-PD-1 therapy

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  DOI: 10.1016/j.xcrm.2025.102434
  
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sciencedirect.com/science/article/pii/S2666379125005075
Oct 2025
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Glucocorticoids unleash immune-dependent melanoma control through inhibition of the GARP/TGF-β axis

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1. scibot 25 Oct 2025
  
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  DOI: 10.1158/2159-8290.CD-24-1224
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618275/
Sep 2025
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Differentiation latency and dormancy signatures define fetal liver hematopoietic stem cells at single-cell resolution

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  DOI: 10.1016/j.celrep.2025.116289
  
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1-s2.0-S2589004225017638-main-html.html

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pmc.ncbi.nlm.nih.gov/articles/PMC12483594/
May 2025
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Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.96868
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12077877/
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Macrophages direct location-dependent recall of B cell memory to vaccination

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.005
  
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sciencedirect.com/science/article/pii/S0092867425004076
Apr 2025
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1-s2.0-S258900422500625X-main-html.html

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1. scibot 17 Apr 2025
  
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52.53.155.43/910d735d2d974315eeec93884560c504f16aaecd/1-s2.0-S258900422500625X-main-html.html
Feb 2025
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PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1

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  DOI: 10.1016/j.stem.2025.01.010
  
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sciencedirect.com/science/article/pii/S1934590925000104
Nov 2024
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ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

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1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.cmet.2024.10.015
  
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sciencedirect.com/science/article/pii/S155041312400411X
Sep 2024
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Immune isolation-enabled nanoencapsulation of donor T cells: a promising strategy for mitigating GVHD and treating AML in preclinical models

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1. scibot 12 Sep 2024
  
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  DOI: 10.1136/jitc-2023-008663
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11381671/
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Acyl-coenzyme a binding protein (ACBP) - a risk factor for cancer diagnosis and an inhibitor of immunosurveillance

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1. scibot 12 Sep 2024
  
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  DOI: 10.1186/s12943-024-02098-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11378439/
Aug 2024
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Baf155 controls hematopoietic differentiation and regeneration through chromatin priming

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1. scibot 01 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114558
  
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sciencedirect.com/science/article/pii/S2211124724008878
Jul 2024
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Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.chom.2024.06.003
  
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cell.com/cell-host-microbe/abstract/S1931-3128(24)00197-5
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SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration

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1. scibot 12 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114458
  
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  DOI: 10.1016/j.celrep.2024.114458
  
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sciencedirect.com/science/article/pii/S2211124724007873
May 2024
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Impaired autophagy in myeloid cells aggravates psoriasis-like skin inflammation through the IL-1β/CXCL2/neutrophil axis

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1. scibot 09 May 2024
  
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  DOI: 10.1186/s13578-024-01238-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11069248/
Apr 2024
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The trogocytosis of neutrophils on initial transplanted tumor in mice

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1. scibot 24 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109661
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11033691/
Mar 2024
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Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers

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1. scibot 15 Mar 2024
  
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  DOI: 10.1016/j.ccell.2024.02.013
  
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sciencedirect.com/science/article/pii/S1535610824000576
Feb 2024
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VEGF-C-expressing TAMs rewire the metastatic fate of breast cancer cells

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  DOI: 10.1016/j.celrep.2023.113507
  
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sciencedirect.com/science/article/pii/S221112472301519X
Dec 2023
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The Tumor Immune Microenvironment Architecture Correlates with Risk of Recurrence in Head and Neck Squamous Cell Carcinoma

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  DOI: 10.1158/0008-5472.CAN-23-0379
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10690086/
Jul 2023
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Differentiation latency and dormancy signatures define fetal liver HSCs at single cell resolution

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1. scibot 04 Jul 2023
  
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  DOI: 10.1101/2023.06.01.543314
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10274697/
Jun 2023
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Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner

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  DOI: 10.1016/j.molcel.2023.05.035
  
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sciencedirect.com/science/article/pii/S1097276523004197
May 2023
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Cytotoxic CNS-associated T cells drive axon degeneration by targeting perturbed oligodendrocytes in PLP1 mutant mice

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  DOI: 10.1016/j.isci.2023.106698
  
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Dec 2022
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Clostridium butyricum-induced ω-3 fatty acid 18-HEPE elicits anti-influenza virus pneumonia effects through interferon-λ upregulation

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1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111755
  
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Sep 2022
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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

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  DOI: 10.1016/j.ccell.2022.08.016
  
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Jun 2022
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Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses

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  DOI: 10.1016/j.celrep.2022.110901
  
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Mar 2022
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Mucus sialylation determines intestinal host-commensal homeostasis

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  DOI: 10.1016/j.cell.2022.02.013
  
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sciencedirect.com/science/article/pii/S0092867422001933
Nov 2021
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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

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  DOI: 10.1016/j.celrep.2021.109911
  
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sciencedirect.com/science/article/pii/S221112472101384X
Sep 2021
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Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo

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  DOI: 10.1016/j.celrep.2021.109675
  
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sciencedirect.com/science/article/pii/S2211124721011190
Aug 2021
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Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

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  DOI: 10.1016/j.cell.2021.07.020
  
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sciencedirect.com/science/article/pii/S0092867421008795
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Regulatory T cells play an important role in the prevention of murine melanocytic nevi and melanomas

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1. scibot 04 Aug 2021
  
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  DOI: 10.1158/1940-6207.CAPR-20-0360
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8093326/
Jul 2021
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MYC deficiency impairs the development of effector/memory T lymphocytes

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1. scibot 07 Jul 2021
  
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  DOI: 10.1016/j.isci.2021.102761
  
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sciencedirect.com/science/article/pii/S258900422100729X
May 2021
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Adoptive T Cell Therapy Targeting Different Gene Products Reveals Diverse and Context-Dependent Immune Evasion in Melanoma

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.07.007
  
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sciencedirect.com/science/article/pii/S1074761320303149
Feb 2021
www.cell.com www.cell.com

Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells

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1. scibot 24 Feb 2021
  
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  RRID:AB_394571
  
  DOI: 10.1016/j.celrep.2020.01.008
  
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cell.com/cell-reports/abstract/S2211-1247(20)30017-6
Jan 2021
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Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma

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1. scibot 21 Jan 2021
  
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  DOI: 10.1016/j.celrep.2020.108620
  
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Nov 2020
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Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans

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1. scibot 07 Nov 2020
  
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  DOI: 10.1016/j.molcel.2020.10.012
  
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Sep 2020
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The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.03.004
  
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Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells

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1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.01.008
  
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Nov 2018
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Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation

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1. scibot 05 Nov 2018
  
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Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response

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1. scibot 05 Nov 2018
  
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Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy

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1. scibot 05 Nov 2018
  
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CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties

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1. scibot 05 Nov 2018
  
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Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress

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1. scibot 05 Nov 2018
  
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Nov 2017
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Protein tyrosine phosphatase σ regulates autoimmune encephalomyelitis development

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1. scibot 08 Nov 2017
  
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The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S1074761317301875