55 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
    1
    1. scibot 24 Nov 2024
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      DOI: 10.1016/j.immuni.2024.10.013

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    sciencedirect.com/science/article/pii/S107476132400493X
  3. Sep 2024
  4. www.biorxiv.org www.biorxiv.org
    Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of Type 1 Diabetes
    1
    1. scibot 28 Sep 2024
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      DOI: 10.1101/2024.09.18.613649

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    biorxiv.org/content/10.1101/2024.09.18.613649v1
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    Interleukin-34-orchestrated tumor-associated macrophage reprogramming is required for tumor immune escape driven by p53 inactivation
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.immuni.2024.08.015

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    sciencedirect.com/science/article/pii/S1074761324004151
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    Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy
    1
    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.029

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    sciencedirect.com/science/article/pii/S0092867424009565
  7. Aug 2024
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    Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
    1
    1. scibot 19 Aug 2024
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      DOI: 10.1016/j.immuni.2024.07.010

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    sciencedirect.com/science/article/pii/S1074761324003595
  9. Jul 2024
  10. www.cell.com www.cell.com
    Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.chom.2024.06.003

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    cell.com/cell-host-microbe/abstract/S1931-3128(24)00197-5
  11. Mar 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling
    1
    1. scibot 16 Mar 2024
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      DOI: 10.1084/jem.20221466

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    ncbi.nlm.nih.gov/pmc/articles/PMC10499045/
  13. www.sciencedirect.com www.sciencedirect.com
    Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response
    2
    1. scibot 08 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113929

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    sciencedirect.com/science/article/pii/S2211124724002572
  14. Feb 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
    2
    1. scibot 14 Feb 2024
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      DOI: 10.1016/j.immuni.2024.01.011

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    2. scibot 14 Feb 2024
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      DOI: 10.1016/j.immuni.2024.01.011

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    sciencedirect.com/science/article/pii/S1074761324000360
  16. Jan 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling
    2
    1. scibot 25 Jan 2024
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      DOI: 10.1126/sciadv.adi2012

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    2. scibot 23 Jan 2024
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      DOI: 10.1126/sciadv.adi2012

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    ncbi.nlm.nih.gov/pmc/articles/PMC10798567/
  18. Nov 2023
  19. www.biorxiv.org www.biorxiv.org
    FASlpr gene dosage tunes the extent of lymphoproliferation and T cell differentiation in lupus
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1101/2023.11.01.563607

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    biorxiv.org/content/10.1101/2023.11.01.563607v1
  20. Sep 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.cmet.2023.08.010

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    sciencedirect.com/science/article/pii/S1550413123003315
  22. Jun 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation
    1
    1. scibot 01 Jun 2023
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      DOI: 10.1016/j.immuni.2023.05.004

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    sciencedirect.com/science/article/pii/S1074761323002212
  24. May 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Transcriptional and metabolic programs promote the expansion of follicular helper T cells in lupus-prone mice
    1
    1. scibot 18 May 2023
      RRID:AB_394763

      DOI: 10.1016/j.isci.2023.106774

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    sciencedirect.com/science/article/pii/S2589004223008519
  26. Apr 2023
  27. www.cell.com www.cell.com
    Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment
    1
    1. scibot 07 Apr 2023
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      DOI: 10.1016/j.cell.2023.03.011

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    cell.com/cell/fulltext/S0092-8674(23)00271-4
  28. Mar 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity
    1
    1. scibot 10 Mar 2023
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      DOI: 10.1016/j.cmet.2023.02.013

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    sciencedirect.com/science/article/pii/S1550413123000499
  30. Feb 2023
  31. www.sciencedirect.com www.sciencedirect.com
    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
    1
    1. scibot 03 Feb 2023
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      DOI: 10.1016/j.ccell.2023.01.003

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    sciencedirect.com/science/article/pii/S153561082300003X
  32. Jan 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury
    1
    1. scibot 24 Jan 2023
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      DOI: 10.1016/j.celrep.2023.112035

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    sciencedirect.com/science/article/pii/S2211124723000463
  34. Oct 2022
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cbl-b Restrains Priming of Pathogenic Th17 Cells via the Inhibition of IL-6 Production by Macrophages
    1
    1. scibot 04 Oct 2022
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      DOI: 10.1016/j.isci.2022.105151

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    ncbi.nlm.nih.gov/pmc/articles/PMC9523381/
  36. Aug 2022
  37. www.sciencedirect.com www.sciencedirect.com
    A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity
    1
    1. scibot 02 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111142

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    sciencedirect.com/science/article/pii/S2211124722009512
  38. Jul 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
    1
    1. scibot 27 Jul 2022
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      DOI: 10.1016/j.ccell.2022.06.011

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    sciencedirect.com/science/article/pii/S1535610822002756
  40. Jun 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes
    1
    1. scibot 30 Jun 2022
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      DOI: 10.1016/j.celrep.2022.111011

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    sciencedirect.com/science/article/pii/S2211124722008002
  42. www.sciencedirect.com www.sciencedirect.com
    Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling
    1
    1. scibot 22 Jun 2022
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      DOI: 10.1016/j.chembiol.2022.05.012

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    sciencedirect.com/science/article/pii/S2451945622002045
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis
    1
    1. scibot 03 Jun 2022
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      DOI: 10.1016/j.chom.2022.05.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC9841318/
  44. May 2022
  45. www.sciencedirect.com www.sciencedirect.com
    STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program
    1
    1. scibot 26 May 2022
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      DOI: 10.1016/j.celrep.2022.110838

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    sciencedirect.com/science/article/pii/S2211124722006118
  46. www.sciencedirect.com www.sciencedirect.com
    Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria
    1
    1. scibot 18 May 2022
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      DOI: 10.1016/j.chom.2022.04.013

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    sciencedirect.com/science/article/pii/S1931312822002190
  47. Apr 2022
  48. www.sciencedirect.com www.sciencedirect.com
    Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse
    1
    1. scibot 27 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110747

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    sciencedirect.com/science/article/pii/S2211124722005113
  49. Mar 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer
    1
    1. scibot 31 Mar 2022
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      DOI: 10.1016/j.cell.2022.02.021

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    sciencedirect.com/science/article/pii/S009286742200201X
  51. Oct 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) drives the resolution of allergic asthma
    1
    1. scibot 08 Oct 2021
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      DOI: 10.1016/j.isci.2021.103163

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    sciencedirect.com/science/article/pii/S2589004221011317
  53. Aug 2021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1016/j.cmet.2017.08.008

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    ncbi.nlm.nih.gov/pmc/articles/PMC5627977/
  55. Apr 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells
    1
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      DOI: 10.1016/j.immuni.2021.04.005

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    sciencedirect.com/science/article/pii/S1074761321001679
  57. Feb 2021
  58. insight.jci.org insight.jci.org
    Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation
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      DOI: 10.1172/jci.insight.133393

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    insight.jci.org/articles/view/133393
  59. www.cell.com www.cell.com
    Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade
    1
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      DOI: 10.1016/j.ccell.2020.11.005

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    cell.com/cancer-cell/abstract/S1535-6108(20)30597-3
  60. Jan 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Increased demand for NAD+ relative to ATP drives aerobic glycolysis
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      DOI: 10.1016/j.molcel.2020.12.012

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    sciencedirect.com/science/article/pii/S1097276520309047
  62. Nov 2020
  63. www.frontiersin.org www.frontiersin.org
    Therapeutic Role of Inducible Nitric Oxide Synthase Expressing Myeloid-Derived Suppressor Cells in Acetaminophen-Induced Murine Liver Failure
    1
    1. scibot 14 Nov 2020
      RRID:AB_394763

      DOI: 10.3389/fimmu.2020.574839

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    frontiersin.org/article/10.3389/fimmu.2020.574839/full
  64. Sep 2020
  65. www.sciencedirect.com www.sciencedirect.com
    The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling
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      DOI: 10.1016/j.immuni.2020.03.004

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    sciencedirect.com/science/article/pii/S1074761320301175
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    PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation
    1
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      DOI: 10.1016/j.celrep.2020.02.035

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  67. www.cell.com www.cell.com
    A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function
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  68. Jan 2020
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    NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells
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    Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
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    Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation of Genes Important for Immune Responses
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      DOI: 10.1016/j.immuni.2019.05.006

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    Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor
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      DOI: 10.1016/j.celrep.2019.10.012

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    The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells
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    The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction
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    Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment
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      DOI: 10.1016/j.immuni.2018.12.024

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  77. www.cell.com www.cell.com
    Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies
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      DOI: 10.1016/j.celrep.2019.04.091

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  78. Nov 2018
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    Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse
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  80. Nov 2017
  81. www.sciencedirect.com www.sciencedirect.com
    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
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    A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function
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    Genome Organization Drives Chromosome Fragility
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    Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments
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