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An epigenetic program dictates MYC amplification dynamics that promote transient, extrachromosomal, and inherited genomic events

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sciencedirect.com/science/article/pii/S1097276526006751
May 2026
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Therapeutic reactivation of hippocampal progenitors reverse cognition decline in mice with progressive brain demyelination

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sciencedirect.com/science/article/pii/S2213671126001074
Apr 2026
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MRE11 proximal polyadenylation site-mediated looping impacts transcription and genomic stability

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sciencedirect.com/science/article/pii/S109727652600208X
Mar 2026
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Microhomology-mediated end joining acts directly on replication forks to repair single-ended double-strand breaks

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sciencedirect.com/science/article/pii/S1097276526001309
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Lamin A/C safeguards replication initiation by orchestrating chromatin accessibility and PCNA recruitment

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sciencedirect.com/science/article/pii/S2211124726001531
Feb 2026
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p53 Drives Lung Cancer Regression through a TSC2/TFEB-dependent Senescence Program

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1. scibot 10 Feb 2026
  
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  DOI: 10.1158/2159-8290.CD-25-0525
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12877752/
Nov 2025
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1-s2.0-S258900422502509X-main-html.html

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1. scibot 29 Nov 2025
  
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54.241.53.176/7cc5e5effac0cd4b8778082ce64567b90bcc3f23/1-s2.0-S258900422502509X-main-html.html
Jul 2025
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Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis - ScienceDirect-html.html

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52.53.155.43/baf73dc4816d69ae4de3fa32641dfd7bd010d8a5/Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis - ScienceDirect-html.html
Jun 2025
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Starvation activates ECM-remodeling gene transcription and putative enhancers in fibroblasts despite inducing quiescence

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1. scibot 28 Jun 2025
  
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cell.com/cell-reports/abstract/S2211-1247(25)00667-9
Feb 2025
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Long-range enhancer-controlled genes are hypersensitive to regulatory factor perturbations

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.xgen.2025.100778
  
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sciencedirect.com/science/article/pii/S2666979X25000345
Jan 2025
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1-s2.0-S2589004225000926-main-html.html

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52.53.155.43/0c94331aae05d9204d741911840095cbd9bb9551/1-s2.0-S2589004225000926-main-html.html
Dec 2024
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Dynamic control of RNA-DNA hybrid formation orchestrates DNA2 activation at stalled forks by RNAPII and DDX39A

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sciencedirect.com/science/article/pii/S1097276524009894
Aug 2024
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Mrc1 regulates parental histone segregation and heterochromatin inheritance

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1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.molcel.2024.07.002
  
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Adult c‐Kit(+) progenitor cells are necessary for maintenance and regeneration of olfactory neurons

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  DOI: 10.1002/cne.23653
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23653/full
Apr 2024
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Functional sensory circuits built from neurons of two species

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  DOI: 10.1016/j.cell.2024.03.042
  
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sciencedirect.com/science/article/pii/S0092867424003581
Mar 2024
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C17orf80 binds the mitochondrial genome to promote its replication

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1. scibot 10 Mar 2024
  
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  DOI: 10.1083/jcb.202302037
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10484793/
Oct 2023
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Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer

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  DOI: 10.1016/j.celrep.2023.113144
  
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sciencedirect.com/science/article/pii/S2211124723011567
Jul 2023
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A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling

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1. scibot 21 Jul 2023
  
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sciencedirect.com/science/article/pii/S1097276523004719
Jun 2023
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Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

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1. scibot 23 Jun 2023
  
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sciencedirect.com/science/article/pii/S0092867423005913
Mar 2023
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The conserved histone chaperone Spt6 is strongly required for DNA replication and genome stability

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sciencedirect.com/science/article/pii/S2211124723002759
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Colchicine exerts anti-atherosclerotic and ‑plaque-stabilizing effects targeting foam cell formation

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  DOI: 10.1096/fj.202201469R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201469R
Jul 2022
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Efficient and strand-specific profiling of replicating chromatin with enrichment and sequencing of protein-associated nascent DNA in mammalian cells

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  DOI: 10.1038/s41596-021-00520-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9261918/
Jun 2022
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Invading viral DNA triggers dsRNA synthesis by RNA polymerase II to activate antiviral RNA interference in Drosophila

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sciencedirect.com/science/article/pii/S2211124722007628
Jan 2022
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Eukaryotic elongation factor 2 kinase regulates foam cell formation via translation of CD36

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  DOI: 10.1096/fj.202101034R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101034R
Sep 2021
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DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity

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sciencedirect.com/science/article/pii/S2211124721011712
Aug 2021
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Continuous-trait probabilistic model for comparing multi-species functional genomic data

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1. scibot 14 Aug 2021
  
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  DOI: 10.1016/j.cels.2018.05.022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6107375/
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Untitled document

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  DOI: 10.1523/JNEUROSCI.3392-17.2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5990977/
Jul 2021
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Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis

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  DOI: 10.1016/j.stem.2019.03.006
  
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sciencedirect.com/science/article/pii/S1934590919301055
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Acetylation of Cytidine in mRNA Promotes Translation Efficiency

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  DOI: 10.1016/j.cell.2018.10.030
  
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sciencedirect.com/science/article/pii/S0092867418313837
Jun 2021
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Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model

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sciencedirect.com/science/article/pii/S1534580721004779
May 2021
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Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication

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Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium

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  DOI: 10.1016/j.stem.2020.06.021
  
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sciencedirect.com/science/article/pii/S1934590920302885
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Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold

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1. scibot 08 May 2021
  
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  DOI: 10.1016/j.neuron.2020.06.035
  
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sciencedirect.com/science/article/pii/S089662732030489X
Apr 2021
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Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle

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1. scibot 29 Apr 2021
  
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  DOI: 10.1016/j.cmet.2020.08.011
  
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sciencedirect.com/science/article/pii/S1550413120304241
Sep 2020
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Mechanism of Virus Attenuation by Codon Pair Deoptimization

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  DOI: 10.1016/j.celrep.2020.107586
  
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sciencedirect.com/science/article/pii/S2211124720305350
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PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells

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  RRID:AB_395993
  
  DOI: 10.1016/j.ccell.2018.06.007
  
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Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria

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1. scibot 15 Sep 2020
  
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  DOI: 10.1016/j.devcel.2020.02.011
  
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Abnormal organization during neurodevelopment in a mouse model of Sandhoff disease

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.neures.2019.07.004
  
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The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.devcel.2019.05.015
  
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Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.stem.2019.03.006
  
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Ca2+-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.04.003
  
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The Mcm2-Ctf4-Polα Axis Facilitates Parental Histone H3-H4 Transfer to Lagging Strands

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1. scibot 05 Nov 2018
  
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Untitled document

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1. scibot 05 Nov 2018
  
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Continuous-Trait Probabilistic Model for Comparing Multi-species Functional Genomic Data

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The Dorsal Wave of Neocortical Oligodendrogenesis Begins Embryonically and Requires Multiple Sources of Sonic Hedgehog

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Checkpoint Kinase Rad53 Couples Leading- and Lagging-Strand DNA Synthesis under Replication Stress

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Nov 2017
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A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer

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1. scibot 08 Nov 2017
  
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Salvianolic Acids Enhance Cerebral Angiogenesis and Neurological Recovery by Activating JAK2/STAT3 Signaling Pathway after Ischemic Stroke in Mice

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Spatial Activation of TORC1 Is Regulated by Hedgehog and E2F1 Signaling in the Drosophila Eye

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1. scibot 08 Nov 2017
  
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Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation

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