48 Matching Annotations
  1. Apr 2024
  2. www.nature.com www.nature.com
    A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells
    1
    1. scibot 10 Apr 2024
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      DOI: 10.1038/s41418-024-01289-3

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    nature.com/articles/s41418-024-01289-3
  3. Jan 2024
  4. www.sciencedirect.com www.sciencedirect.com
    A mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass
    2
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.molcel.2023.11.038

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    2. scibot 11 Jan 2024
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      DOI: 10.1016/j.molcel.2023.11.038

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    sciencedirect.com/science/article/pii/S1097276523010146
  5. Dec 2023
  6. www.sciencedirect.com www.sciencedirect.com
    A mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass
    1
    1. scibot 29 Dec 2023
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      DOI: 10.1016/j.molcel.2023.11.038

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    sciencedirect.com/science/article/pii/S1097276523010146
  7. Oct 2023
  8. www.mdpi.com www.mdpi.com
    PolyQ-Expansion Causes Mitochondria Fragmentation Independent of Huntingtin and Is Distinct from Traumatic Brain Injury (TBI)/Mechanical Stress-Mediated Fragmentation Which Results from Cell Death
    1
    1. scibot 13 Oct 2023
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      DOI: 10.3390/cells12192406

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    mdpi.com/2073-4409/12/19/2406
  9. May 2023
  10. www.sciencedirect.com www.sciencedirect.com
    Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex
    1
    1. scibot 17 May 2023
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      DOI: 10.1016/j.devcel.2023.04.015

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    sciencedirect.com/science/article/pii/S1534580723001910
  11. Apr 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112434

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    sciencedirect.com/science/article/pii/S221112472300445X
  13. Jan 2023
  14. www.sciencedirect.com www.sciencedirect.com
    DGKB mediates radioresistance by regulating DGAT1-dependent lipotoxicity in glioblastoma
    1
    1. scibot 06 Jan 2023
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      DOI: 10.1016/j.xcrm.2022.100880

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    sciencedirect.com/science/article/pii/S266637912200444X
  15. Nov 2022
  16. www.sciencedirect.com www.sciencedirect.com
    Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells
    1
    1. scibot 03 Nov 2022
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      DOI: 10.1016/j.molcel.2022.10.005

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    sciencedirect.com/science/article/pii/S1097276522009625
  17. May 2022
  18. www.sciencedirect.com www.sciencedirect.com
    DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism
    1
    1. scibot 25 May 2022
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      DOI: 10.1016/j.devcel.2022.04.020

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    sciencedirect.com/science/article/pii/S1534580722003069
  19. Mar 2022
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Applying Sodium Carbonate Extraction Mass Spectrometry to Investigate Defects in the Mitochondrial Respiratory Chain
    1
    1. scibot 18 Mar 2022
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      DOI: 10.3389/fcell.2022.786268

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    ncbi.nlm.nih.gov/pmc/articles/PMC8921082/
  21. Feb 2022
  22. www.sciencedirect.com www.sciencedirect.com
    The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation
    1
    1. scibot 04 Feb 2022
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      DOI: 10.1016/j.molcel.2022.01.008

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    sciencedirect.com/science/article/pii/S1097276522000089
  23. Aug 2021
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis
    1
    1. scibot 16 Aug 2021
      RRID:AB_396417

      DOI: 10.1186/s13024-021-00470-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC8353748/
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    1. scibot 10 Aug 2021
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      DOI: 10.1111/jnc.14621

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14621
  26. www.jneurosci.org www.jneurosci.org
    Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis
    1
    1. scibot 06 Aug 2021
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      DOI: 10.1523/JNEUROSCI.2462-16.2016

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    jneurosci.org/content/37/6/1413
  27. Jul 2021
  28. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 31 Jul 2021
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      DOI: 10.1016/j.celrep.2019.03.040

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    sciencedirect.com/science/article/pii/S2211124719303560
  29. www.nature.com www.nature.com
    BAX mitochondrial integration is regulated allosterically by its α1−α2 loop
    1
    1. scibot 22 Jul 2021
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      DOI: 10.1038/s41418-021-00815-x

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    nature.com/articles/s41418-021-00815-x
  30. Jun 2021
  31. www.sciencedirect.com www.sciencedirect.com
    Oncogene-regulated release of extracellular vesicles
    1
    1. scibot 12 Jun 2021
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      DOI: 10.1016/j.devcel.2021.05.014

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    sciencedirect.com/science/article/pii/S1534580721004433
  32. May 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity
    1
    1. scibot 26 May 2021
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      DOI: 10.1016/j.celrep.2021.109180

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    sciencedirect.com/science/article/pii/S2211124721005258
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ethanol Enhances Hyperthermia-Induced Cell Death in Human Leukemia Cells
    1
    1. scibot 19 May 2021
      AB_396417

      DOI: 10.3390/ijms22094948

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    ncbi.nlm.nih.gov/pmc/articles/PMC8125413/
  35. www.sciencedirect.com www.sciencedirect.com
    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
    1
    1. scibot 05 May 2021
      RRID:AB_396417

      DOI: 10.1016/j.celrep.2021.109076

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    sciencedirect.com/science/article/pii/S2211124721004071
  36. Apr 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Structure of detergent-activated BAK dimers derived from the inert monomer
    1
    1. scibot 07 Apr 2021
      RRID:AB_396417

      DOI: 10.1016/j.molcel.2021.03.014

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    sciencedirect.com/science/article/pii/S1097276521001829
  38. Mar 2021
  39. www.sciencedirect.com www.sciencedirect.com
    The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism
    1
    1. scibot 17 Mar 2021
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      DOI: 10.1016/j.celrep.2021.108869

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    sciencedirect.com/science/article/pii/S2211124721001832
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease
    1
    1. scibot 11 Mar 2021
      RRID:AB_396417

      DOI: 10.1186/s13024-021-00435-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC7941983/
  41. Nov 2020
  42. www.sciencedirect.com www.sciencedirect.com
    Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum
    1
    1. scibot 13 Nov 2020
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      DOI: 10.1016/j.neuron.2020.10.005

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    sciencedirect.com/science/article/pii/S089662732030773X
  43. Sep 2020
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target
    1
    1. scibot 26 Sep 2020
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      DOI: 10.1038/s41419-020-2463-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC7181796/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation
    1
    1. scibot 23 Sep 2020
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      DOI: 10.7554/eLife.55896

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    ncbi.nlm.nih.gov/pmc/articles/PMC7498260/
  46. www.sciencedirect.com www.sciencedirect.com
    Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I
    1
    1. scibot 15 Sep 2020
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      DOI: 10.1016/j.celrep.2020.107541

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    sciencedirect.com/science/article/pii/S2211124720304411
  47. www.sciencedirect.com www.sciencedirect.com
    Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress
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    1. scibot 13 Sep 2020
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      DOI: 10.1016/j.cmet.2020.06.002

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    sciencedirect.com/science/article/pii/S155041312030303X
  48. journals.plos.org journals.plos.org
    JC Virus infected choroid plexus epithelial cells produce extracellular vesicles that infect glial cells independently of the virus attachment receptor
    1
    1. scibot 04 Sep 2020
      cytochrome c

      DOI: 10.1371/journal.ppat.1008371

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    journals.plos.org/plospathogens/article
  49. www.sciencedirect.com www.sciencedirect.com
    SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP
    1
    1. scibot 04 Sep 2020
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      DOI: 10.1016/j.celrep.2020.107640

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    sciencedirect.com/science/article/pii/S2211124720305933
  50. Jan 2020
  51. www.sciencedirect.com www.sciencedirect.com
    Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.molcel.2019.06.040

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    sciencedirect.com/science/article/pii/S1097276519304976
  52. link.springer.com link.springer.com
    Untitled document
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    1. scibot 13 Jan 2020
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      DOI: 10.1007/978-1-4939-8861-7_14

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    link.springer.com/protocol/10.1007/978-1-4939-8861-7_14
  53. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
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      DOI: 10.1016/j.celrep.2019.03.040

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    sciencedirect.com/science/article/pii/S2211124719303560
  54. www.sciencedirect.com www.sciencedirect.com
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      AB_396417

      DOI: 10.1016/j.celrep.2019.01.081

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    sciencedirect.com/science/article/pii/S221112471930110X
  55. Nov 2018
  56. www.sciencedirect.com www.sciencedirect.com
    Ensemble Properties of Bax Determine Its Function
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    sciencedirect.com/science/article/pii/S0969212618302521
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    Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S2211124718306193
  58. www.sciencedirect.com www.sciencedirect.com
    The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer
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    sciencedirect.com/science/article/pii/S1097276517308845
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    Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design
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    sciencedirect.com/science/article/pii/S1097276517308365
  60. Nov 2017
  61. www.sciencedirect.com www.sciencedirect.com
    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
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    1. scibot 08 Nov 2017
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610817303641
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    Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages
    1
    1. scibot 08 Nov 2017
      RRID:AB_396417

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1931312817303037
  63. www.sciencedirect.com www.sciencedirect.com
    Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex
    1
    1. scibot 08 Nov 2017
      AB_396417

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1097276517304410
  64. www.sciencedirect.com www.sciencedirect.com
    Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria
    1
    1. scibot 08 Nov 2017
      AB_396417

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1097276517304409
  65. www.sciencedirect.com www.sciencedirect.com
    PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise
    1
    1. scibot 08 Nov 2017
      AB_396417

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S155041311730236X
  66. www.jneurosci.org www.jneurosci.org
    Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis
    1
    1. scibot 08 Nov 2017
      AB_396417

      Curator: @chewbeccax

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    jneurosci.org/content/37/6/1413
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disordered clusters of Bak dimers rupture mitochondria during apoptosis
    1
    1. scibot 08 Nov 2017
      AB_396417

      Curator: @kaitlinsung

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    ncbi.nlm.nih.gov/pmc/articles/PMC5302884/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability
    1
    1. scibot 08 Nov 2017
      AB_396417

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC5016092/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer
    1
    1. scibot 08 Nov 2017
      AB_396417

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC5127641/