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Granzyme K is a driver of age-related tissue remodeling and functional decline independently of age-associated immune dysfunction

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1. scibot 14 Nov 2026
  
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sciencedirect.com/science/article/pii/S1074761326004401
Oct 2026
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Punicalin targets RSV glycoprotein and fusion protein at non-overlapping sites to prevent viral escape

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1. scibot 01 Oct 2026
  
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sciencedirect.com/science/article/pii/S2666379126004957
Sep 2026
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A secreted protein from Hungatella hathewayi inhibits colorectal cancer by reprogramming intratumoral CD14b+ macrophages

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1. scibot 11 Sep 2026
  
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  DOI: 10.1016/j.celrep.2026.117988
  
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sciencedirect.com/science/article/pii/S2211124726010661
Jun 2026
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Remodeling of the immune-metabolic landscape triggered by long-term high-altitude exposure

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1. scibot 22 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117376
  
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sciencedirect.com/science/article/pii/S2211124726004547
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Regulation of antiviral immunity by PD-1 during respiratory syncitial virus infection and upon vaccination

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1. scibot 09 Jun 2026
  
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sciencedirect.com/science/article/pii/S2589004226015324
May 2026
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Loss of tumor suppressor NF2 mediates resistance to CAR T cell and anti-PD-1 therapy: Strategies to restore immunotherapy sensitivity

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1. scibot 29 May 2026
  
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sciencedirect.com/science/article/pii/S2666634026001522
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NK cell dysfunction and interferon gamma production underlie autoinflammation in mevalonate kinase deficiency

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1. scibot 01 May 2026
  
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sciencedirect.com/science/article/pii/S107476132600138X
Apr 2026
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Palmitic acid reprograms neutrophils to compromise vascular integrity and promote breast cancer lung metastasis

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1. scibot 25 Apr 2026
  
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sciencedirect.com/science/article/pii/S1074761326001378
Feb 2026
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MafB is a conserved transcriptional regulator of macrophage development and functional identity across tissues and species

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1. scibot 27 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.012
  
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sciencedirect.com/science/article/pii/S1074761326000336
Jan 2026
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A combined strategy of EGFR-MET bispecific antibody and HER3 ADC to overcome osimertinib resistance in NSCLC

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1. scibot 30 Jan 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12847129/
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e013832.full-html.html

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1. scibot 27 Jan 2026
  
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54.241.53.176/ca60c4c2a1e906c1762fed2c822dc77ccf0438f0/e013832.full-html.html
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Synergistic effects of Clostridium butyricum and Akkermansia muciniphila-derived postbiotics ameliorate DSS-induced colitis and associated tumorigenesis through immunomodulation and microbiota regulation in mice

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1. scibot 06 Jan 2026
  
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  DOI: 10.1128/msystems.00689-25
  
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journals.asm.org/doi/10.1128/msystems.00689-25
Nov 2025
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Monocyte-derived cells promote transient insult-induced brain injury by enhancing CD8+ T cell response

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1. scibot 18 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116528
  
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sciencedirect.com/science/article/pii/S2211124725012999
Aug 2025
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A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers

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1. scibot 08 Aug 2025
  
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A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression

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1. scibot 05 Aug 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-4774
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12317733/
Jul 2025
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Role of Macrophage PARP1 in the Regulation of Crosstalk between Adipose Immune Cells and Adipocytes during Diet-induced Obesity

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1. scibot 01 Jul 2025
  
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  DOI: 10.1101/2025.06.20.660762
  
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biorxiv.org/content/10.1101/2025.06.20.660762v1
Jun 2025
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Itaconate promotes inflammatory responses in tissue-resident alveolar macrophages and exacerbates acute lung injury

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1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.cmet.2025.05.012
  
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sciencedirect.com/science/article/pii/S1550413125002682
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Amitriptyline revitalizes ICB response via dually inhibiting Kynurenine/indole and serotonin pathways of tryptophan metabolism in ovarian cancer

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1. scibot 14 Jun 2025
  
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  DOI: 10.1016/j.isci.2024.111488
  
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sciencedirect.com/science/article/pii/S2589004224027159
May 2025
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Microbiota-derived urocanic acid triggered bytyrosine kinase inhibitors potentiates cancer immunotherapy efficacy

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.chom.2025.04.022
  
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sciencedirect.com/science/article/pii/S1931312825001556
Feb 2025
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The combination of Clostridium butyricum and Akkermansia muciniphila mitigates DSS-induced colitis and attenuates colitis-associated tumorigenesis by modulating gut microbiota and reducing CD8+ T cells in mice

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1. scibot 20 Feb 2025
  
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  DOI: 10.1128/msystems.01567-24
  
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sciencedirect.com/org/science/article/pii/S2379507725000066
Jan 2025
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A functional cardiac patch promotes cardiac repair by modulating the CCR2− cardiac-resident macrophage niche and their cell crosstalk

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1. scibot 30 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2025.101932
  
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sciencedirect.com/science/article/pii/S2666379125000059
Nov 2024
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Dachengqi decoction ameliorated liver injury in liver fibrosis mice by maintaining gut vascular barrier integrity

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1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.phymed.2024.156272
  
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sciencedirect.com/science/article/pii/S0944711324009280
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Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.008
  
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sciencedirect.com/science/article/pii/S1535610824003969
Jul 2024
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Innate immune memory after brain injury drives inflammatory cardiac dysfunction

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.06.028
  
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sciencedirect.com/science/article/pii/S0092867424007025
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Intestinal microbiota imbalance resulted by anti-Toxoplasma gondii immune responses aggravate gut and brain injury

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1. scibot 07 Jul 2024
  
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  DOI: 10.1186/s13071-024-06349-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11221008/
Jun 2024
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Protocol for building an in vitro model of M2-like tumor-associated macrophages with lactic acid or conditioned medium from Lewis cells

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1. scibot 27 Jun 2024
  
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  DOI: 10.1016/j.xpro.2024.103120
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11193043/
Mar 2024
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Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers

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1. scibot 15 Mar 2024
  
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S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function

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1. scibot 12 Mar 2024
  
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  DOI: 10.1186/s13046-024-02985-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10921725/
Feb 2024
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CYP7B1-mediated 25-hydroxycholesterol degradation maintains quiescence-activation balance and improves therapeutic potential of mesenchymal stem cells

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1. scibot 28 Feb 2024
  
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  DOI: 10.1016/j.chembiol.2024.01.009
  
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sciencedirect.com/science/article/pii/S245194562400045X
Jan 2024
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MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension

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  DOI: 10.1126/sciadv.adk6524
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10798563/
Oct 2023
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Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response

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1. scibot 26 Oct 2023
  
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  DOI: 10.1016/j.xcrm.2023.101234
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10591062/
May 2023
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Vascular traffic control of neutrophil recruitment to the liver by microbiota-endothelium crosstalk

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1. scibot 17 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112507
  
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sciencedirect.com/science/article/pii/S2211124723005181
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Mechanisms Regulating the loss of Tregs in HUPO mice that Develop Spontaneous Inflammatory Arthritis

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1. scibot 14 May 2023
  
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  DOI: 10.1016/j.isci.2023.106734
  
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sciencedirect.com/science/article/pii/S2589004223008118
Jan 2023
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Specialized functions and sexual dimorphism explain the functional diversity of the myeloid populations during glioma progression

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1. scibot 12 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111971
  
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sciencedirect.com/science/article/pii/S2211124722018757
Nov 2022
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STAT3 promotes differentiation of monocytes to MDSCs via CD39/CD73-adenosine signal pathway in oral squamous cell carcinoma

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1. scibot 29 Nov 2022
  
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  DOI: 10.1007/s00262-022-03336-9
  
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link.springer.com/article/10.1007/s00262-022-03336-9
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STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation

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Inhibition of SRC-mediated integrin signaling in bone marrow niche enhances hematopoietic stem cell function

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Differential regulation of transcription factor T-bet induction during NK cell development and T helper-1 cell differentiation

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Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint

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Fine-tuning of MEK signaling is pivotal for limiting B and T cell activation

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Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections

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Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity

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Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection

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RSPO2 inhibits BMP signaling to promote self-renewal in acute myeloid leukemia

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Neuroprotective response and efficacy of intravenous administration of mesenchymal stem cells in traumatic brain injury mice

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Untitled document

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Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC

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SMRT Regulates Metabolic Homeostasis and Adipose Tissue Macrophage Phenotypes in Tandem

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  DOI: 10.1210/endocr/bqaa132
  
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Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP

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Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism

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  DOI: 10.7554/eLife.59258
  
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Sep 2020
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B1 AND B2 KININ RECEPTOR BLOCKADE IMPROVES PSORIASIS‐LIKE DISEASE

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  DOI: 10.1111/bph.15077
  
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Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis

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Sarm1 knockout protects against early but not late axonal degeneration in experimental allergic encephalomyelitis

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  DOI: 10.1371/journal.pone.0235110
  
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Lymphocyte-Specific Function of the DNA Polymerase Epsilon Subunit Pole3 Revealed by Neomorphic Alleles

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Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation

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LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis

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Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells

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Suppression of Microglial Activation Is Neuroprotective in a Mouse Model of Human Retinitis Pigmentosa

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