91 Matching Annotations
  1. Last 7 days
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    Notch2 signaling governs activated B cells to form memory B cells
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    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114454

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    sciencedirect.com/science/article/pii/S2211124724007836
  3. Jun 2024
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    Opposing effects of pre-existing antibody and memory T cell help on the dynamics of recall germinal centers
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    1. scibot 05 Jun 2024
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      DOI: 10.1016/j.immuni.2024.05.009

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    sciencedirect.com/science/article/pii/S1074761324002632
  5. May 2024
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    Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation
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    1. scibot 21 May 2024
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    sciencedirect.com/science/article/pii/S1074761324002280
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    Innervation of nociceptor neurons in the spleen promotes germinal center responses and humoral immunity
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    1. scibot 21 May 2024
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    sciencedirect.com/science/article/pii/S0092867424004537
  8. Apr 2024
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    Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses
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    1. scibot 26 Apr 2024
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    sciencedirect.com/science/article/pii/S1074761324001432
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    Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection
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    1. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S1074761324001377
  11. Mar 2024
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    Protocol to assess bioenergetics and mitochondrial fuel usage in murine autoreactive immunocytes using the Seahorse Extracellular Flux Analyzer
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    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.xpro.2024.102971

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    sciencedirect.com/science/article/pii/S2666166724001369
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
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    1. scibot 08 Mar 2024
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    sciencedirect.com/science/article/pii/S1535610824000540
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    SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions
    2
    1. scibot 08 Mar 2024
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    2. scibot 08 Mar 2024
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    sciencedirect.com/science/article/pii/S1535610824000552
  15. Feb 2024
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    GLUT1-mediated glucose import in B cells is critical for anaplerotic balance and humoral immunity
    2
    1. scibot 13 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724000676
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    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
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    1. scibot 06 Feb 2024
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      DOI: 10.1158/2159-8290.CD-22-1401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
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    NGFR regulates stromal cell activation in germinal centers
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    1. scibot 02 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724000330
  19. Jan 2024
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    Ipsilateral immunization after a prior SARS-CoV-2 mRNA vaccination elicits superior B cell responses compared to contralateral immunization
    1
    1. scibot 09 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113665

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    sciencedirect.com/science/article/pii/S2211124723016765
  21. Nov 2023
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    Germinal centers output clonally diverse plasma cell populations expressing high- and low-affinity antibodies
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    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.cell.2023.10.022

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    sciencedirect.com/science/article/pii/S009286742301173X
  23. Aug 2023
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    Glucose Oxidation-Dependent Survival of Activated B Cells Provides a Putative Novel Therapeutic Target for Lupus Treatment
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    ncbi.nlm.nih.gov/pmc/articles/PMC10448027/
  25. May 2023
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    STAT3 signaling in B cells controls germinal center zone organization and recycling
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    1. scibot 18 May 2023
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      DOI: 10.1016/j.celrep.2023.112512

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    sciencedirect.com/science/article/pii/S2211124723005235
  27. Apr 2023
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    Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B cell fate decisions and yields T cell-depleted lymphomas
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    1. scibot 05 Apr 2023
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      DOI: 10.1101/2023.02.13.528351

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    52.53.155.43/f4b0048cc7a871a681c39b83d20e963f1e4d0c2b/2023.02.13.528351v1.full-html.html
  29. Mar 2023
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    B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection
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    1. scibot 11 Mar 2023
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    sciencedirect.com/science/article/pii/S1074761323000778
  31. Jan 2023
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    Continuous germinal center invasion contributes to the diversity of the immune response
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    1. scibot 28 Jan 2023
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      DOI: 10.1016/j.cell.2022.11.032

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    sciencedirect.com/science/article/pii/S0092867422015070
  33. Dec 2022
  34. 52.53.155.43 52.53.155.43
    cd-22-0561-html.html
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  35. Nov 2022
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    STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation
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    1. scibot 29 Nov 2022
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    sciencedirect.com/science/article/pii/S107476132200591X
  37. Sep 2022
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    Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice
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    sciencedirect.com/science/article/pii/S1074761322004976
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    cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells
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    sciencedirect.com/science/article/pii/S2211124722012050
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    A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut
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    sciencedirect.com/science/article/pii/S1074761322004125
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    Lineage tracing reveals B cell antibody class switching is stochastic, cell-autonomous, and tuneable
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    1. scibot 16 Sep 2022
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    sciencedirect.com/science/article/pii/S1074761322003971
  42. Aug 2022
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    Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus
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    sciencedirect.com/science/article/pii/S1074761322003399
  44. Jun 2022
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    BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen
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    sciencedirect.com/science/article/pii/S1074761322002230
  46. May 2022
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    YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation
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    sciencedirect.com/science/article/pii/S2211124722005423
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    Germinal center expansion but not plasmablast differentiation is proportional to peptide-MHCII density via CD40-CD40L signaling strength
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    sciencedirect.com/science/article/pii/S2211124722005277
  49. Mar 2022
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    RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants
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    sciencedirect.com/science/article/pii/S2589004222003133
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    Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa
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    sciencedirect.com/science/article/pii/S2211124722002972
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    Follicular T Cells Optimize the Germinal Center Response to SARS-CoV-2 Protein Vaccination in Mice
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      DOI: 10.1016/j.celrep.2022.110399

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    sciencedirect.com/science/article/pii/S2211124722001206
  53. Feb 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Bacterial infection disrupts established germinal center reactions through monocyte recruitment and impaired metabolic adaptation
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    sciencedirect.com/science/article/pii/S1074761322000425
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    Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers
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      DOI: 10.1016/j.immuni.2022.01.002

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    sciencedirect.com/science/article/pii/S1074761322000310
  56. Jan 2022
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    Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint
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    1. scibot 19 Jan 2022
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      DOI: 10.1016/j.celrep.2021.110259

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    sciencedirect.com/science/article/pii/S221112472101771X
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    Fine-tuning of MEK signaling is pivotal for limiting B and T cell activation
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    1. scibot 12 Jan 2022
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      DOI: 10.1016/j.celrep.2021.110223

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    sciencedirect.com/science/article/pii/S2211124721017277
  59. Dec 2021
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability
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    1. scibot 04 Dec 2021
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      DOI: 10.1016/j.immuni.2021.10.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC8554075/
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    Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses
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    Vectored antibody gene delivery restores host B and T cell control of persistent viral infection
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  63. Nov 2021
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    Temporal dynamics of persistent germinal centers and memory B cell differentiation following respiratory virus infection
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    Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition
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  66. Sep 2021
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    Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation
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    Negative feedback by NUR77/Nr4a1 restrains B cell clonal dominance during early T-dependent immune responses
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  69. Aug 2021
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    Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity
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    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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  74. Jul 2021
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    Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche
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      Armenian hamster anti-Mouse CD95 (JO2)

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    The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis
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    Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus
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  78. May 2021
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    Bach2 attenuates IL-2R signaling to control Treg homeostasis and Tfr development
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    A Hyper-IgM Syndrome Mutation in Activation-Induced Cytidine Deaminase Disrupts G-Quadruplex Binding and Genome-wide Chromatin Localization
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  81. Apr 2021
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    Follicular regulatory T cells produce neuritin to regulate B cells
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    TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate
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    Positive selection of IgG+ over IgM+ B cells in the germinal center reaction
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  85. Mar 2021
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    Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies
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    Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells
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      Anti-mouse CD95-PE-Cy7 (Jo2) 1/200

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    Quick and easy purification of murine untouched naive B cells or germinal center B cells by MACS
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  89. Dec 2020
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    The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses
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    Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates
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    miR-29 Sustains B Cell Survival and Controls Terminal Differentiation via Regulation of PI3K Signaling
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  93. Nov 2020
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    Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection
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    Cyclin D3 Governs Clonal Expansion of Dark Zone Germinal Center B Cells
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  96. Oct 2020
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    Continued Bcl6 Expression Prevents the Transdifferentiation of Established Tfh Cells into Th1 Cells during Acute Viral Infection
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  98. Sep 2020
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    Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses
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    Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation
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    Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response
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    B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer’s Patches
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    Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells
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  104. Jan 2020
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    Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
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    Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection
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    Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria
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    IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression
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    Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting
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    PD-1 Signaling Promotes Control of Chronic Viral Infection by Restricting Type-I-Interferon-Mediated Tissue Damage
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    Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis
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    Protein Amounts of the MYC Transcription Factor Determine Germinal Center B Cell Division Capacity
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      DOI: 10.1016/j.immuni.2019.06.013

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    Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells
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      DOI: 10.1016/j.celrep.2018.11.096

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  115. Nov 2018
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    MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis
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    LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells
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    Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity
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    B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells
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    Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells
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  123. Nov 2017
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    Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
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