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Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype

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1. scibot 07 Sep 2025
  
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  DOI: 10.1158/2159-8290.CD-24-1208
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12409281/
Jun 2025
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A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rβ deficiency

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115902
  
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sciencedirect.com/science/article/pii/S2211124725006734
Nov 2024
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Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.010
  
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sciencedirect.com/science/article/pii/S1535610824003982
Jul 2024
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Single-cell chromatin accessibility and transposable element landscapes reveal shared features of tissue-residing immune cells

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1. scibot 24 Jul 2024
  
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  DOI: 10.1016/j.immuni.2024.06.015
  
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sciencedirect.com/science/article/pii/S1074761324003212
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Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.06.012
  
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sciencedirect.com/science/article/pii/S0092867424006524
Apr 2024
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Enhancing comparative T cell receptor repertoire analysis in small biological samples through pooling homologous cell samples from multiple mice

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1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.crmeth.2024.100753
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11045977/
Feb 2024
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Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs

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1. scibot 13 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113751
  
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sciencedirect.com/science/article/pii/S2211124724000792
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Immunomodulatory effects and improved outcomes with cisplatin- versus carboplatin-based chemotherapy plus atezolizumab in urothelial cancer

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1. scibot 02 Feb 2024
  
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  DOI: 10.1016/j.xcrm.2024.101393
  
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sciencedirect.com/science/article/pii/S2666379124000028
Jan 2024
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Benzosceptrin C induces lysosomal degradation of PD-L1 and promotes antitumor immunity by targeting DHHC3

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.xcrm.2023.101357
  
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sciencedirect.com/science/article/pii/S2666379123005748
Nov 2023
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An obesogenic diet increases atherosclerosis through promoting microbiota dysbiosis-induced gut lymphocyte trafficking into the periphery

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1. scibot 02 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113350
  
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sciencedirect.com/science/article/pii/S2211124723013621
Oct 2023
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Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine

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1. scibot 14 Oct 2023
  
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  RRID:AB_396959
  
  DOI: 10.1016/j.xcrm.2023.101229
  
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sciencedirect.com/science/article/pii/S2666379123004068
May 2023
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CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer

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1. scibot 18 May 2023
  
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  DOI: 10.1016/j.medj.2023.04.008
  
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sciencedirect.com/science/article/pii/S266663402300140X
Jan 2023
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Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy

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1. scibot 19 Jan 2023
  
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  RRID:AB_396959
  
  DOI: 10.1016/j.ccell.2022.12.008
  
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sciencedirect.com/science/article/pii/S1535610822005943
Mar 2022
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The oxygen sensor prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells

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1. scibot 09 Mar 2022
  
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  DOI: 10.7554/eLife.70555
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8896828/
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CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4

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1. scibot 02 Mar 2022
  
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  DOI: 10.1016/j.ccell.2022.02.003
  
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sciencedirect.com/science/article/pii/S1535610822000368
Sep 2021
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Baseline iron status and presence of anaemia determine the course of systemic Salmonella infection following oral iron supplementation in mice

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1. scibot 08 Sep 2021
  
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  DOI: 10.1016/j.ebiom.2021.103568
  
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sciencedirect.com/science/article/pii/S2352396421003613
May 2021
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The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.07.012
  
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sciencedirect.com/science/article/pii/S1074761320303198
Apr 2021
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Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance

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1. scibot 22 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.12.023
  
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  RRID:AB_396959 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820306711
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A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance

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1. scibot 10 Apr 2021
  
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  DOI: 10.1016/j.immuni.2021.03.020
  
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sciencedirect.com/science/article/pii/S1074761321001321
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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

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1. scibot 01 Apr 2021
  
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  DOI: 10.1016/j.immuni.2021.03.007
  
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sciencedirect.com/science/article/pii/S1074761321001199
Mar 2021
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Functional characterization of the dural sinuses as a neuroimmune interface

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1. scibot 08 Mar 2021
  
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  DOI: 10.1016/j.cell.2020.12.040
  
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sciencedirect.com/science/article/pii/S0092867420317621
Feb 2021
diabetes.diabetesjournals.org diabetes.diabetesjournals.org

Peptides Derived From Insulin Granule Proteins are Targeted by CD8+ T Cells Across MHC Class I Restrictions in Humans and NOD Mice.

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1. scibot 28 Feb 2021
  
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  DOI: 10.2337/db20-0013
  
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diabetes.diabetesjournals.org/content/69/12/2678
Nov 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity

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1. scibot 03 Nov 2020
  
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  DOI: 10.1016/j.cell.2020.09.062
  
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pubmed.ncbi.nlm.nih.gov/33125891/
Sep 2020
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GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab

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1. scibot 17 Sep 2020
  
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  RRID:AB_396959
  
  DOI: 10.7554/eLife.49392
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7108862/
Jan 2020
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c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells

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1. scibot 13 Jan 2020
  
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  RRID:AB_396959
  
  DOI: 10.1016/j.celrep.2019.04.090
  
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sciencedirect.com/science/article/pii/S2211124719305704