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Jul 2025
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Oxidative stress and Kras mutation in Mist1+ cells act in a double-hit manner to drive gastric tumorigenesis

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  DOI: 10.1016/j.celrep.2025.116014
  
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Jun 2025
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Lysophosphatidic acid and sphingosine-1-phosphate are apical polarity cues in multiple organoid systems

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  DOI: 10.1016/j.celrep.2025.115842
  
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sciencedirect.com/science/article/pii/S2211124725006138
Apr 2025
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ARHGAP12 suppresses F-actin assembly to control epithelial tight junction mechanics and paracellular leak pathway permeability

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1-s2.0-S2589004225005346-main-html.html

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Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens

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  DOI: 10.1016/j.cell.2025.03.020
  
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Feb 2025
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Dual-acting gene therapy targeting HIF1A and HIF2A by RNA interference mitigates retinal degeneration in two mouse models of AMD

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  DOI: 10.1101/2024.11.29.626080
  
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52.53.155.43/7e17e3f83e73e58cfd7cd8e7a37f05adb3a75ce8/2024.11.29.626080.full-html.html
Jan 2025
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Kinesin-like motor protein KIF23 maintains neural stem and progenitor cell pools in the developing cortex

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1. scibot 25 Jan 2025
  
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  DOI: 10.1038/s44318-024-00327-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11729872/
Nov 2024
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PI3K/Akt inhibition promotes AR activity and prostate cancer cell proliferation through p35-CDK5 modulation

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  DOI: 10.1016/j.bbadis.2024.167568
  
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sciencedirect.com/science/article/pii/S0925443924005623
Aug 2024
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Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines

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  DOI: 10.1016/j.celrep.2024.114616
  
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Jul 2024
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The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells

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May 2024
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Ependymal cells undergo astrocyte-like reactivity in response to neuroinflammation

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1. scibot 09 May 2024
  
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  DOI: 10.1111/jnc.16120
  
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2024.01.01.573838.full-html.html

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52.53.155.43/d7265ccf2d93378f45840445f700070207b97c0d/2024.01.01.573838.full-html.html
Mar 2024
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Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model

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1. scibot 01 Mar 2024
  
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  DOI: 10.7554/eLife.89453
  
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  DOI: 10.7554/eLife.89453
  
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elifesciences.org/articles/89453
Feb 2024
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ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells

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  DOI: 10.1016/j.celrep.2024.113818
  
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Jan 2024
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Oligodendrocyte-derived LGI3 and its receptor ADAM23 organize juxtaparanodal Kv1 channel clustering for short-term synaptic plasticity

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  DOI: 10.1016/j.celrep.2023.113634
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10828548/
Oct 2023
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Cellular senescence promotes progenitor cell expansion during axolotl limb regeneration

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.devcel.2023.09.009
  
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Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.stem.2023.09.002
  
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sciencedirect.com/science/article/pii/S1934590923003235
Aug 2023
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8151.full-html.html

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  DOI: 10.1523/jneurosci.4415-13.2014
  
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52.53.155.43/a740bcbd960c842102701a97bf23fd457d1e5f46/8151.full-html.html
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S-acylation of the Wnt receptor Frizzled-5 by zDHHC5 controls its cellular localization and synaptogenic activity in the rodent hippocampus

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1. scibot 10 Aug 2023
  
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Jun 2023
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Targeting 14-3-3ζ by a small-molecule compound AI-34 maintains epithelial barrier integrity and alleviates colitis in mice via stabilizing β-catenin

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sciencedirect.com/science/article/pii/S1347861323000348
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Genetic recording of in vivo cell proliferation by ProTracer

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  DOI: 10.1038/s41596-023-00833-8
  
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nature.com/articles/s41596-023-00833-8
Apr 2023
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Multicellular rosettes link mesenchymal-epithelial transition to radial intercalation in the mouse axial mesoderm

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Feb 2023
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DDR2 coordinates EMT and metabolic reprogramming as a shared effector of FOXQ1 and SNAI1

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  DOI: 10.1158/2767-9764.crc-22-0013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9881645/
Jan 2023
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Controlling human organoid symmetry breaking reveals signaling gradients drive segmentation clock waves

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  DOI: 10.1016/j.cell.2022.12.042
  
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Dec 2022
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YAP regulates the liver size during the fasting-refeeding transition in mice

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  DOI: 10.1016/j.apsb.2022.12.011
  
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Nov 2022
aacrjournals.org aacrjournals.org

DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1

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  DOI: 10.1158/2767-9764.CRC-22-0013
  
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aacrjournals.org/cancerrescommun/article/2/11/1388/710518/DDR2-Coordinates-EMT-and-Metabolic-Reprogramming
Oct 2022
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Expression analyses of polo-like kinase 4 (Plk4), a gene product responsible for autosomal recessive microcephaly and Seckel syndrome, during mouse brain development

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  DOI: 10.1159/000526914
  
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karger.com/Article/FullText/526914
Sep 2022
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Robust genome editing via modRNA-based Cas9 or base editor in human pluripotent stem cells

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  DOI: 10.1016/j.crmeth.2022.100290
  
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sciencedirect.com/science/article/pii/S2667237522001722
Jul 2022
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Multifocal organoids reveal clonal associations between synchronous intestinal tumors with pervasive heterogeneous drug responses

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  DOI: 10.1038/s41525-022-00313-0
  
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nature.com/articles/s41525-022-00313-0
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PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis

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  DOI: 10.1016/j.celrep.2022.111125
  
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sciencedirect.com/science/article/pii/S2211124722009317
Jun 2022
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NR2F1 is a barrier to dissemination of early stage breast cancer cells.

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  DOI: 10.1158/0008-5472.CAN-21-4145
  
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aacrjournals.org/cancerres/article/82/12/2313/699348/NR2F1-Is-a-Barrier-to-Dissemination-of-Early-Stage
Mar 2022
academic.oup.com academic.oup.com

Canonical thyroid hormone receptor β action stimulates hepatocyte proliferation in male mice

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1. scibot 08 Mar 2022
  
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  DOI: 10.1210/endocr/bqac003
  
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academic.oup.com/endo/article/163/3/bqac003/6509895
Feb 2022
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Matrix remodeling controls a nuclear lamin A/C-emerin network that directs Wnt-regulated stem cell fate

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1. scibot 13 Feb 2022
  
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  DOI: 10.1016/j.devcel.2022.01.015
  
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sciencedirect.com/science/article/pii/S1534580722000405
Dec 2021
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Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses

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1. scibot 21 Dec 2021
  
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  DOI: 10.1002/advs.202103360
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202103360
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14-3-3 proteins stabilize LGI1-ADAM22 levels to regulate seizure thresholds in mice

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1. scibot 15 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110107
  
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Stretching of the retinal pigment epithelium contributes to zebrafish optic cup morphogenesis

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Colocalization of Wnt/β-catenin and ACTH signaling pathways and paracrine regulation in aldosterone producing adenoma

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Quantitative live-cell imaging and computational modeling shed new light on endogenous WNT/CTNNB1 signaling dynamics

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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines

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ECM alterations in Fndc3a (Fibronectin Domain Containing Protein 3A) deficient zebrafish cause temporal fin development and regeneration defects

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RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes

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Identification and Characterization of GABAA Receptor Autoantibodies in Autoimmune Encephalitis

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Increased Synthesis of Chondroitin Sulfate Proteoglycan Promotes Adult Hippocampal Neurogenesis in Response to Enriched Environment

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Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation

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NHERF1 Is Required for Localization of PMCA2 and Suppression of Early Involution in the Female Lactating Mammary Gland

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Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation

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Lithium Chloride Increases COX-2 Expression and PGE2 Production in a Human Granulosa-Lutein SVOG Cell Line Via a GSK-3β/β-Catenin Signaling Pathway

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α-Ketoglutarate links p53 to cell fate during tumour suppression

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Regulation of the endosomal SNX27-retromer by OTULIN

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Transcriptional profiling of human neural precursors post alcohol exposure reveals impaired neurogenesis via dysregulation of ERK signaling and miR‐145

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Lithium Chloride Increases COX-2 Expression and PGE2 Production in a Human Granulosa-Lutein SVOG Cell Line Via a GSK-3β/β-Catenin Signaling Pathway

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A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis

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Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism

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Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein

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Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population

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Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation

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HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis

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The Mammalian Crumbs Complex Defines a Distinct Polarity Domain Apical of Epithelial Tight Junctions

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Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging

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Proteolytic Restriction of Chordin Range Underlies BMP Gradient Formation

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Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells

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Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling

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Constitutive androstane receptor induced-hepatomegaly is partially via yes-associated protein activation

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Shigella flexneri Disruption of Cellular Tension Promotes Intercellular Spread

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Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure

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Proteolytic Restriction of Chordin Range Underlies BMP Gradient Formation

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Defining the Adult Neural Stem Cell Niche Proteome Identifies Key Regulators of Adult Neurogenesis

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HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer

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Centrosome anchoring regulates progenitor properties and cortical formation

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Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia‐like phenotypes in mice

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Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis

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Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription

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Apical Restriction of the Planar Cell Polarity Component VANGL in Pancreatic Ducts Is Required to Maintain Epithelial Integrity

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Endonuclease VIII-like 1 deficiency impairs survival of newly generated hippocampal neurons and memory performance in young-adult male mice

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Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation

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An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells

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Full length RTEL1 is required for the elongation of the single-stranded telomeric overhang by telomerase

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CRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast Sensitivity

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Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier

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Microglia mediate HIV-1 gp120-induced synaptic degeneration in spinal pain neural circuits

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Patient-Derived Organoids Predict Chemoradiation Responses of Locally Advanced Rectal Cancer

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Canonical Wnt5b Signaling Directs Outlying Nkx2.5+ Mesoderm into Pacemaker Cardiomyocytes

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Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy

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The miR-216a-Dot1l Regulatory Axis Is Necessary and Sufficient for Müller Glia Reprogramming during Retina Regeneration

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Increased Cholesterol Biosynthesis Is a Key Characteristic of Breast Cancer Stem Cells Influencing Patient Outcome

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Early dorsomedial tissue interactions regulate gyrification of distal neocortex

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HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis

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Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus

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Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin

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Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration

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Untitled document

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APC2 controls dendrite development by promoting microtubule dynamics

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Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential

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Adult Neurogenesis Is Sustained by Symmetric Self-Renewal and Differentiation

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Epithelial Sodium Channel Regulates Adult Neural Stem Cell Proliferation in a Flow-Dependent Manner

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A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3α and GSK3β in Regulating Embryonic Stem Cell Fate.

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mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis

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Establishment and characterization of induced pluripotent stem cells from placental mesenchymal stromal cells

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A role for endothelial nitric oxide synthase in intestinal stem cell proliferation and mesenchymal colorectal cancer

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Sonic Hedgehog and WNT Signaling Promote Adrenal Gland Regeneration in Male Mice

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YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme

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Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins

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Differential Wnt signaling activity limits epithelial gland development to the anti-mesometrial side of the mouse uterus - ScienceDirect

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A Requirement for Mena, an Actin Regulator, in Local mRNA Translation in Developing Neurons

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Mitosis can drive cell cannibalism through entosis

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Type XVII collagen coordinates proliferation in the interfollicular epidermis

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Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells

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A Gradient of Glycolytic Activity Coordinates FGF and Wnt Signaling during Elongation of the Body Axis in Amniote Embryos

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Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding

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Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread

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Multi-organ Mapping of Cancer Risk

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Identification and Characterization of GABAA Receptor Autoantibodies in Autoimmune Encephalitis

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