115 Matching Annotations
  1. Nov 2024
  2. elifesciences.org elifesciences.org
    Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells
    1
    1. scibot 07 Nov 2024
      AB_397555

      DOI: 10.7554/eLife.89725

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    elifesciences.org/articles/89725
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Cyclophilin D, regulator of the mitochondrial permeability transition, impacts bone development and fracture repair
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.bone.2024.117258

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    sciencedirect.com/science/article/pii/S8756328224002473
  5. Aug 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Neuroepithelial bodies and terminal bronchioles are niches for distinctive club cells that repair the airways following acute notch inhibition
    1
    1. scibot 27 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114654

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    sciencedirect.com/science/article/pii/S2211124724010052
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ventricular-subventricular zone stem cell niche adaptations in a mouse model of post-infectious hydrocephalus
    1
    1. scibot 22 Aug 2024
      RRID:AB_397555

      DOI: 10.3389/fnins.2024.1429829

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    ncbi.nlm.nih.gov/pmc/articles/PMC11322059/
  8. elifesciences.org elifesciences.org
    Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
    1
    1. scibot 02 Aug 2024
      AB_397555

      DOI: 10.7554/eLife.17047

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    elifesciences.org/content/5/e17047
  9. Jul 2024
  10. www.cell.com www.cell.com
    Regulation of the DLC3 tumor suppressor by a novel phosphoswitch
    1
    1. scibot 18 Jul 2024
      RRID:AB_397555

      DOI: 10.1016/j.isci.2024.110203

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    cell.com/iscience/abstract/S2589-0042(24)01428-7
  11. Jun 2024
  12. www.sciencedirect.com www.sciencedirect.com
    PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer
    1
    1. scibot 21 Jun 2024
      RRID:AB_397555

      DOI: 10.1016/j.cmet.2024.05.015

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    sciencedirect.com/science/article/pii/S1550413124001918
  13. www.sciencedirect.com www.sciencedirect.com
    Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation
    1
    1. scibot 21 Jun 2024
      RRID:AB_397555

      DOI: 10.1016/j.isci.2024.110199

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    sciencedirect.com/science/article/pii/S258900422401424X
  14. May 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell competition drives bronchiolization and pulmonary fibrosis
    1
    1. scibot 23 May 2024
      RRID:AB_397555

      DOI: 10.21203/rs.3.rs-4177351/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11092845/
  16. 52.53.155.43 52.53.155.43
    SIRT1 mediates the antagonism of Wnt/β-catenin pathway by vitamin D in colon carcinoma cells
    1
    1. scibot 04 May 2024
      Β D   Cat# 610154

      DOI: 10.1101/2024.01.21.576539

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    52.53.155.43/696f49a3546de66e1af8cab87bfc89cda4bd0257/2024.01.21.576539v1.full-html.html
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of tumor-associated AXIN1 missense mutations identifies variants that activate β-catenin signaling
    1
    1. scibot 04 May 2024
      RRID:AB_397555

      DOI: 10.1158/0008-5472.CAN-23-2268

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    ncbi.nlm.nih.gov/pmc/articles/PMC11063763/
  18. Mar 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis
    1
    1. scibot 27 Mar 2024
      RRID:AB_397555

      DOI: 10.1016/j.isci.2024.109400

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959657/
  20. Jan 2024
  21. www.science.org www.science.org
    An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
    1
    1. scibot 18 Jan 2024
      RRID:AB_397555

      DOI: 10.1126/sciadv.adg4055

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    science.org/doi/10.1126/sciadv.adg4055
  22. Dec 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth
    1
    1. scibot 20 Dec 2023
      RRID:AB_397555

      DOI: 10.1016/j.chembiol.2023.11.006

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    sciencedirect.com/science/article/pii/S245194562300421X
  24. Nov 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Targeted perturbation of signaling-driven condensates
    1
    1. scibot 28 Nov 2023
      RRID:AB_397555

      DOI: 10.1016/j.molcel.2023.10.023

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    sciencedirect.com/science/article/pii/S1097276523008602
  26. Jul 2023
  27. www.sciencedirect.com www.sciencedirect.com
    An E-cadherin-actin clutch translates the mechanical force of cortical flow for cell-cell contact to inhibit epithelial cell locomotion
    1
    1. scibot 22 Jul 2023
      RRID:AB_397555

      DOI: 10.1016/j.devcel.2023.06.011

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    sciencedirect.com/science/article/abs/pii/S153458072300326X
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
    1
    1. scibot 14 Jul 2023
      RRID:AB_397555

      DOI: 10.1126/sciadv.adg4055

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    ncbi.nlm.nih.gov/pmc/articles/PMC10337909/
  29. Jun 2023
  30. www.sciencedirect.com www.sciencedirect.com
    ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation
    1
    1. scibot 23 Jun 2023
      RRID:AB_397555

      DOI: 10.1016/j.chembiol.2023.05.010

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    sciencedirect.com/science/article/pii/S2451945623001538
  31. May 2023
  32. www.sciencedirect.com www.sciencedirect.com
    A Wnt-induced lncRNA-DGCR5 splicing switch drives tumor-promoting inflammation in esophageal squamous cell carcinoma
    1
    1. scibot 25 May 2023
      RRID:AB_397555

      DOI: 10.1016/j.celrep.2023.112542

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    sciencedirect.com/science/article/pii/S2211124723005533
  33. www.sciencedirect.com www.sciencedirect.com
    Efficient and scalable generation of primordial germ cells in 2D culture using basement membrane extract overlay
    1
    1. scibot 24 May 2023
      RRID:AB_397555

      DOI: 10.1016/j.crmeth.2023.100488

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    sciencedirect.com/science/article/pii/S266723752300111X
  34. www.sciencedirect.com www.sciencedirect.com
    Modeling human ectopic pregnancies with trophoblast and vascular organoids
    1
    1. scibot 24 May 2023
      RRID:AB_397555

      DOI: 10.1016/j.celrep.2023.112546

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    sciencedirect.com/science/article/pii/S2211124723005570
  35. www.sciencedirect.com www.sciencedirect.com
    Multimodal characterization of murine gastruloid development
    1
    1. scibot 20 May 2023
      RRID:AB_397555

      DOI: 10.1016/j.stem.2023.04.018

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    sciencedirect.com/science/article/pii/S1934590923001704
  36. Apr 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development
    1
    1. scibot 13 Apr 2023
      RRID:AB_397555

      DOI: 10.1016/j.devcel.2023.03.016

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    sciencedirect.com/science/article/pii/S1534580723001326
  38. Mar 2023
  39. www.sciencedirect.com www.sciencedirect.com
    A micropattern-based assay to study contact inhibition of locomotion and entosis of adherent human and canine cells in vitro
    1
    1. scibot 28 Mar 2023
      RRID:AB_397555

      DOI: 10.1016/j.xpro.2023.102186

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    sciencedirect.com/science/article/pii/S2666166723001442
  40. www.sciencedirect.com www.sciencedirect.com
    Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma
    1
    1. scibot 11 Mar 2023
      RRID:AB_397555

      DOI: 10.1016/j.celrep.2023.112212

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    sciencedirect.com/science/article/pii/S2211124723002231
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma
    1
    1. scibot 05 Mar 2023
      RRID:AB_397555

      DOI: 10.1158/1541-7786.MCR-22-0090

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    ncbi.nlm.nih.gov/pmc/articles/PMC9444924/
  42. Feb 2023
  43. www.mdpi.com www.mdpi.com
    CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2
    1
    1. scibot 15 Feb 2023
      RRID:AB_397555

      DOI: 10.3390/cells12040555

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    mdpi.com/2073-4409/12/4/555
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver
    1
    1. scibot 02 Feb 2023
      RRID:AB_397555

      DOI: 10.7554/eLife.82311

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    ncbi.nlm.nih.gov/pmc/articles/PMC9889086/
  45. Jan 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis
    1
    1. scibot 24 Jan 2023
      RRID:AB_397555

      DOI: 10.1016/j.devcel.2022.12.006

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    sciencedirect.com/science/article/pii/S1534580722008723
  47. www.sciencedirect.com www.sciencedirect.com
    Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin
    1
    1. scibot 11 Jan 2023
      AB_397555

      DOI: 10.1016/j.cell.2022.12.016

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    sciencedirect.com/science/article/pii/S009286742201529X
  48. Dec 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling
    1
    1. scibot 31 Dec 2022
      RRID:AB_397555

      DOI: 10.3390/pharmaceutics14122774

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    ncbi.nlm.nih.gov/pmc/articles/PMC9781674/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wnt antagonism without TGFβ induces rapid MSC chondrogenesis via increasing AJ interactions and restricting lineage commitment
    1
    1. scibot 30 Dec 2022
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      DOI: 10.1016/j.isci.2022.105713

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    ncbi.nlm.nih.gov/pmc/articles/PMC9792887/
  51. www.sciencedirect.com www.sciencedirect.com
    Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development
    1
    1. scibot 06 Dec 2022
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      DOI: 10.1016/j.immuni.2022.11.003

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    sciencedirect.com/science/article/pii/S1074761322005933
  52. Nov 2022
  53. www.nature.com www.nature.com
    mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity
    1
    1. scibot 29 Nov 2022
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      DOI: 10.1038/s41467-022-34763-y

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    nature.com/articles/s41467-022-34763-y
  54. Oct 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfments
    1
    1. scibot 01 Oct 2022
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      DOI: 10.1016/j.isci.2022.105144

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    ncbi.nlm.nih.gov/pmc/articles/PMC9519618/
  56. Aug 2022
  57. journals.plos.org journals.plos.org
    Wnt5a–Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions
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    1. scibot 31 Aug 2022
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      DOI: 10.1371/journal.pbio.3001759

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    journals.plos.org/plosbiology/article
  58. www.sciencedirect.com www.sciencedirect.com
    Vitamin D receptor activation is a feasible therapeutic target to impair adrenocortical tumorigenesis
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    1. scibot 30 Aug 2022
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      DOI: 10.1016/j.mce.2022.111757

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    sciencedirect.com/science/article/pii/S0303720722002052
  59. www.sciencedirect.com www.sciencedirect.com
    SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells
    1
    1. scibot 26 Aug 2022
      RRID:AB_397555

      DOI: 10.1016/j.celrep.2022.111247

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    sciencedirect.com/science/article/pii/S2211124722010658
  60. Jul 2022
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
    1
    1. scibot 06 Jul 2022
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      DOI: 10.1158/0008-5472.CAN-20-4218

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    ncbi.nlm.nih.gov/pmc/articles/PMC9056178/
  62. May 2022
  63. www.sciencedirect.com www.sciencedirect.com
    An injury-responsive Rac-to-Rho GTPase switch drives activation of muscle stem cells through rapid cytoskeletal remodeling
    1
    1. scibot 25 May 2022
      RRID:AB_397555

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      DOI: 10.15252/embj.2019104319

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    2. scibot 03 Sep 2020
      mouse monoclonal antibody to β‐catenin

      DOI: 10.15252/embj.2019104319

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  116. www.sciencedirect.com www.sciencedirect.com
    E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration
    1
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      RRID:AB_397555

      DOI: 10.1016/j.devcel.2019.12.016

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  117. Jan 2020
  118. www.sciencedirect.com www.sciencedirect.com
    Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells
    1
    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.celrep.2019.10.079

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    sciencedirect.com/science/article/pii/S2211124719314019
  119. www.sciencedirect.com www.sciencedirect.com
    Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1
    1
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      RRID:AB_397555

      DOI: 10.1016/j.celrep.2019.11.035

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  120. www.sciencedirect.com www.sciencedirect.com
    Maintenance of Primary Hepatocyte Functions In Vitro by Inhibiting Mechanical Tension-Induced YAP Activation
    1
    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.celrep.2019.10.128

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  121. www.sciencedirect.com www.sciencedirect.com
    Truncated BRPF1 Cooperates with Smoothened to Promote Adult Shh Medulloblastoma
    1
    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.celrep.2019.11.046

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    sciencedirect.com/science/article/pii/S2211124719315281
  122. mcr.aacrjournals.org mcr.aacrjournals.org
    Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin–Independent Targets by Proteomics
    1
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      RRID:AB_397555

      DOI: 10.1158/1541-7786.MCR-18-1154

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  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice
    1
    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.7554/eLife.45961

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    ncbi.nlm.nih.gov/pmc/articles/PMC6544437/
  124. www.sciencedirect.com www.sciencedirect.com
    Endometrial Axin2+ Cells Drive Epithelial Homeostasis, Regeneration, and Cancer following Oncogenic Transformation
    1
    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.stem.2019.11.012

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    sciencedirect.com/science/article/pii/S1934590919304679
  125. www.sciencedirect.com www.sciencedirect.com
    The Making of a Flight Feather: Bio-architectural Principles and Adaptation
    1
    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.cell.2019.11.008

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    sciencedirect.com/science/article/pii/S0092867419312292
  126. www.sciencedirect.com www.sciencedirect.com
    Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells
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      RRID:AB_397555

      DOI: 10.1016/j.cell.2019.10.015

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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
    1
    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.ccell.2019.08.003

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  128. www.sciencedirect.com www.sciencedirect.com
    Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human
    1
    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.celrep.2019.11.104

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    sciencedirect.com/science/article/pii/S2211124719316043
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.ebiom.2019.06.046

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  130. www.sciencedirect.com www.sciencedirect.com
    GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis
    1
    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.celrep.2019.05.016

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    sciencedirect.com/science/article/pii/S2211124719306278
  131. www.sciencedirect.com www.sciencedirect.com
    WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis
    1
    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.devcel.2017.10.007

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    sciencedirect.com/science/article/pii/S1534580717308201
  132. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.cmet.2019.01.002

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    sciencedirect.com/science/article/pii/S1550413119300026
  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_397555

      DOI: 10.7554/eLife.40556

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    ncbi.nlm.nih.gov/pmc/articles/PMC6301792/
  134. www.sciencedirect.com www.sciencedirect.com
    Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells
    1
    1. scibot 12 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.cell.2019.03.013

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    sciencedirect.com/science/article/pii/S0092867419302752
  135. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:AB_397555

      DOI: 10.1016/j.celrep.2019.01.009

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    sciencedirect.com/science/article/pii/S2211124719300178
  136. Nov 2018
  137. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 05 Nov 2018
      RRID:AB_397555

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    sciencedirect.com/science/article/pii/S2211124718314943
  138. www.sciencedirect.com www.sciencedirect.com
    Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling
    1
    1. scibot 05 Nov 2018
      RRID:AB_397555

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    sciencedirect.com/science/article/pii/S2211124718312038
  139. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2451945618301879
  140. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Growth hormone‐releasing hormone receptor antagonists modify molecular machinery in the progression of prostate cancer
    1
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      RRID:AB_397555

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    onlinelibrary.wiley.com/doi/full/10.1002/pros.23648
  141. www.sciencedirect.com www.sciencedirect.com
    The Polyploid State Plays a Tumor-Suppressive Role in the Liver
    1
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      RRID:AB_397555

      Curator: @Jmenke

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  142. Nov 2017
  143. www.sciencedirect.com www.sciencedirect.com
    Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover
    1
    1. scibot 08 Nov 2017
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1534580717307347
  144. www.sciencedirect.com www.sciencedirect.com
    Diurnal Oscillations in Liver Mass and Cell Size Accompany Ribosome Assembly Cycles
    1
    1. scibot 08 Nov 2017
      Β-cateninBD BiosciencesCat#610154

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867417304282
  145. academic.oup.com academic.oup.com
    Clinical Identification of Oncogenic Drivers and Copy-Number Alterations in Pituitary Tumors
    1
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      AB_397555

      Curator: @chewbeccax

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    academic.oup.com/endo/article/158/7/2284/3805374/Clinical-Identification-of-Oncogenic-Drivers-and
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    Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells
    1
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      AB_397555

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0896627317305998
  147. www.sciencedirect.com www.sciencedirect.com
    Sam68 Allows Selective Targeting of Human Cancer Stem Cells
    1
    1. scibot 08 Nov 2017
      Purified Mouse anti-beta-catenin

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S2451945617301897
  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CaMKII Signaling Stimulates Mef2c Activity In Vitro but Only Minimally Affects Murine Long Bone Development in vivo
    1
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      AB_397555

      Curator: @Zeljana_Babic

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    ncbi.nlm.nih.gov/pmc/articles/PMC5352711/
  149. elifesciences.org elifesciences.org
    Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
    2
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      AB_397555

      Curator: @gabimpine

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  150. www.sciencedirect.com www.sciencedirect.com
    Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
    1
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      AB_397555

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