141 Matching Annotations
  1. Sep 2024
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    Positional information modulates transient regeneration-activated cell states during vertebrate appendage regeneration.
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    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.isci.2024.110737

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    sciencedirect.com/science/article/pii/S258900422401962X
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    Microbiota regulates neonatal disease tolerance to virus-evoked necrotizing enterocolitis by shaping the STAT1-NLRC5 axis in the intestinal epithelium
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    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.chom.2024.08.013

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    sciencedirect.com/science/article/pii/S1931312824003202
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    Metabolic Reprogramming Promotes Neural Crest Migration via Yap/Tead Signaling
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    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.devcel.2020.03.005

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    sciencedirect.com/science/article/pii/S1534580720301891
  5. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    1. scibot 13 Sep 2024
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      DOI: 10.1038/s41467-024-51831-7

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    nature.com/articles/s41467-024-51831-7
  6. Aug 2024
  7. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TMEM252 inhibits epithelial–mesenchymal transition and progression in papillary thyroid carcinoma by regulating Notch1 expression
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    1. scibot 25 Aug 2024
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      DOI: 10.1002/hed.27922

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    onlinelibrary.wiley.com/doi/10.1002/hed.27922
  8. Jun 2024
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    Efficient intracellular drug delivery by co-administration of two antibodies against cell adhesion molecule 1
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    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.jconrel.2024.05.035

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    sciencedirect.com/science/article/pii/S0168365924003195
  10. May 2024
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    PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer
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    1. scibot 01 May 2024
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      DOI: 10.1016/j.celrep.2024.114176

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    sciencedirect.com/science/article/pii/S2211124724005047
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    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
    2
    1. scibot 01 May 2024
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      DOI: 10.1016/j.stem.2024.04.002

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      DOI: 10.1016/j.stem.2024.04.002

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    sciencedirect.com/science/article/pii/S1934590924001292
  13. Apr 2024
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    Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer
    1
    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.xcrm.2024.101504

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    sciencedirect.com/science/article/pii/S2666379124001733
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    Basal delamination during mouse gastrulation primes pluripotent cells for differentiation
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    1. scibot 05 Apr 2024
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    sciencedirect.com/science/article/pii/S153458072400176X
  16. Mar 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INHBA is enriched in HPV-negative oropharyngeal squamous cell carcinoma and promotes cancer progression
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    1. scibot 02 Mar 2024
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      DOI: 10.1158/2767-9764.CRC-23-0258

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    ncbi.nlm.nih.gov/pmc/articles/PMC10901070/
  18. Feb 2024
  19. www.sciencedirect.com www.sciencedirect.com
    Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury
    2
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.stem.2024.01.013

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      DOI: 10.1016/j.stem.2024.01.013

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    sciencedirect.com/science/article/pii/S1934590924000432
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    Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity
    1
    1. scibot 07 Feb 2024
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      DOI: 10.1016/j.immuni.2024.01.002

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    sciencedirect.com/science/article/pii/S107476132400027X
  21. Jan 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis
    1
    1. scibot 26 Jan 2024
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      DOI: 10.1016/j.ebiom.2023.104587

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    ncbi.nlm.nih.gov/pmc/articles/PMC10192437/
  23. www.sciencedirect.com www.sciencedirect.com
    Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.stem.2023.12.003

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    sciencedirect.com/science/article/pii/S1934590923004332
  24. Dec 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Murine trophoblast organoids as a model for trophoblast development and CRISPR-Cas9 screening
    1
    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.devcel.2023.11.007

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    sciencedirect.com/science/article/pii/S1534580723005841
  26. Nov 2023
  27. www.sciencedirect.com www.sciencedirect.com
    p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113486

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    sciencedirect.com/science/article/pii/S2211124723014985
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    Incorporation of human iPSC-derived stromal cells creates a pancreatic cancer organoid with heterogeneous cancer-associated fibroblasts
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113420

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    sciencedirect.com/science/article/pii/S2211124723014328
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    A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.devcel.2023.10.010

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    sciencedirect.com/science/article/pii/S1534580723005518
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    p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.celrep.2023.112659

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    sciencedirect.com/science/article/pii/S2211124723006708
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    Functional screening of amplification outlier oncogenes in organoid models of early tumorigenesis
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      DOI: 10.1016/j.celrep.2023.113355

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    sciencedirect.com/science/article/pii/S2211124723013670
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    Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1016/j.stem.2023.10.002

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    sciencedirect.com/science/article/pii/S1934590923003648
  33. Oct 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.devcel.2023.10.003

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    sciencedirect.com/science/article/pii/S1534580723005233
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    Single-cell mapping identifies MSI+ cells as a common origin for diverse subtypes of pancreatic cancer
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.ccell.2023.09.008

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    sciencedirect.com/science/article/abs/pii/S1535610823003240
  36. 52.53.155.43 52.53.155.43
    Transgene directed induction of a stem cell-derived human embryo model
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1101/2023.06.15.545082

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    52.53.155.43/5a401c55d861c2dcc062c9d148face33c192a62e/2023.06.15.545082v1.full-html.html
  37. Aug 2023
  38. 52.53.155.43 52.53.155.43
    Estrogen receptor alpha (ESR1) regulates uterine epithelial lineage specification and homeostasis
    1
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.isci.2023.107568

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    52.53.155.43/84eeef9da15fe9a95b2ca3a2a2fb759f332e8c64/PIIS2589004223016450-html.html
  39. Jun 2023
  40. www.sciencedirect.com www.sciencedirect.com
    A single-cell level comparison of human inner ear organoids with the human cochlea and vestibular organs
    1
    1. scibot 08 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112623

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    sciencedirect.com/science/article/pii/S2211124723006344
  41. May 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The First Transcriptomic Atlas of the Adult Lacrimal Gland Reveals Epithelial Complexity and Identifies Novel Progenitor Cells in Mice
    1
    1. scibot 31 May 2023
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      DOI: 10.3390/cells12101435

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    ncbi.nlm.nih.gov/pmc/articles/PMC10216974/
  43. www.mdpi.com www.mdpi.com
    Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis
    1
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      DOI: 10.3390/ijms23095265

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    mdpi.com/1422-0067/23/9/5265/htm
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    Immune mechanisms shape the clonal landscape during early progression of prostate cancer
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    1. scibot 06 May 2023
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    sciencedirect.com/science/article/pii/S1534580723001806
  45. Apr 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Sp1-like protein KLF13 acts as a negative feedback regulator of TGF-β signaling and fibrosis
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      DOI: 10.1016/j.celrep.2023.112367

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    sciencedirect.com/science/article/pii/S2211124723003789
  47. Mar 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Multiplex imaging of breast cancer lymph node metastases identifies prognostic single-cell populations independent of clinical classifiers
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      DOI: 10.1016/j.xcrm.2023.100977

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    sciencedirect.com/science/article/pii/S2666379123000836
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids
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      DOI: 10.3389/fimmu.2023.1097383

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    ncbi.nlm.nih.gov/pmc/articles/PMC9995983/
  50. www.mdpi.com www.mdpi.com
    Lacrimal Gland Epithelial Cells Shape Immune Responses through the Modulation of Inflammasomes and Lipid Metabolism
    1
    1. scibot 09 Mar 2023
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      DOI: 10.3390/ijms24054309

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    mdpi.com/1422-0067/24/5/4309
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma
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      DOI: 10.1158/1541-7786.MCR-22-0090

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      DOI: 10.1158/1541-7786.MCR-22-0090

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    ncbi.nlm.nih.gov/pmc/articles/PMC9444924/
  52. Feb 2023
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of iNOS/NO Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer
    1
    1. scibot 09 Feb 2023
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      DOI: 10.1158/1541-7786.MCR-22-0509

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    ncbi.nlm.nih.gov/pmc/articles/PMC9890133/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KRAS Mutants Upregulate Integrin β4 to Promote Invasion and Metastasis in Colorectal Cancer
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    1. scibot 09 Feb 2023
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      DOI: 10.1158/1541-7786.MCR-21-0994

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    ncbi.nlm.nih.gov/pmc/articles/PMC9357101/
  55. Jan 2023
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARID1A loss in pancreas leads to islet developmental defect and metabolic disturbance
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      DOI: 10.1016/j.isci.2022.105881

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    Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice
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  130. Feb 2021
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  132. Dec 2020
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    Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors
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    A Comprehensive Structure-Function Study of Neurogenin3 Disease-Causing Alleles during Human Pancreas and Intestinal Organoid Development
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    Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer
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    Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells
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    A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle
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    A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas
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    Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network
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    Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids
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      DOI: 10.1016/j.cmet.2019.05.007

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  162. Nov 2018
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    Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation
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    Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification
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    Combinatorial Targeting by MicroRNAs Co-ordinates Post-transcriptional Control of EMT
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    Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery
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    Helicobacter pylori Employs a Unique Basolateral Type IV Secretion Mechanism for CagA Delivery
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    Paneth Cell Multipotency Induced by Notch Activation following Injury
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    Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis
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    PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transient external force induces phenotypic reversion of malignant epithelial structures via nitric oxide signaling
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    HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model
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    Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry
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    Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo
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    Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
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  176. Nov 2017
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    Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming
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  178. elifesciences.org elifesciences.org
    Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids
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    elifesciences.org/articles/26575
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    Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling
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    Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis
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