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Sec61 translocon inhibitor flavitransin blocks selectively dengue virus polyprotein insertion in the ER with pan-orthoflavivirus antiviral potency

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1. scibot 13 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116642
  
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sciencedirect.com:5037/science/article/pii/S2211124725014147
Nov 2025
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Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks

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1. scibot 08 Nov 2025
  
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  DOI: 10.1016/j.molcel.2025.10.015
  
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sciencedirect.com/science/article/pii/S1097276525008561
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A subset of Orai1α and Orai1β subunits heteromerizes to form CRAC channels

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1. scibot 12 Jun 2025
  
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  DOI: 10.1186/s12964-025-02271-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12131441/
Apr 2024
www.ahajournals.org www.ahajournals.org

New Loss-of-Function Mutations in PCSK9 Reduce Plasma LDL Cholesterol

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1. scibot 18 Apr 2024
  
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  AB_397866
  
  DOI: 10.1161/ATVBAHA.122.318839
  
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New Loss-of-Function Mutations in PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Reduce Plasma LDL (Low-Density Lipoprotein) Cholesterol

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1. scibot 04 Apr 2024
  
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  DOI: 10.1161/ATVBAHA.122.318839
  
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ahajournals.org/doi/abs/10.1161/ATVBAHA.122.318839
Mar 2024
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A sterol analog inhibits hedgehog pathway by blocking cholesterylation of smoothened

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1. scibot 05 Mar 2024
  
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  DOI: 10.1016/j.chembiol.2024.02.002
  
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2. scibot 05 Mar 2024
  
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3. scibot 05 Mar 2024
  
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  DOI: 10.1016/j.chembiol.2024.02.002
  
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sciencedirect.com/science/article/pii/S245194562400076X
Feb 2024
52.53.155.43 52.53.155.43

meng-et-al-2023-new-loss-of-function-mutations-in-pcsk9-reduce-plasma-ldl-cholesterol-html.html

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1. scibot 27 Feb 2024
  
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52.53.155.43/6dc7bb5c3defb3dc565dda6223aa90187b2786e1/meng-et-al-2023-new-loss-of-function-mutations-in-pcsk9-reduce-plasma-ldl-cholesterol-html.html
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 31 Jul 2021
  
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  DOI: 10.1016/j.ccell.2018.08.015
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6179967/
Sep 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Exosomes derived from microglia exposed to elevated pressure amplify the neuroinflammatory response in retinal cells

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1. scibot 12 Sep 2020
  
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  DOI: 10.1002/glia.23880
  
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onlinelibrary.wiley.com/doi/10.1002/glia.23880
www.cell.com www.cell.com

The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation

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1. scibot 04 Sep 2020
  
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  DOI: 10.1016/j.ccell.2018.08.015
  
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cell.com/cancer-cell/fulltext/S1535-6108(18)30375-1
Nov 2018
www.ncbi.nlm.nih.govhttp: www.ncbi.nlm.nih.govhttp:

Untitled document

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6179967/
www.sciencedirect.com www.sciencedirect.com

Untitled document

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610818303751
Nov 2017
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Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S1097276517301302