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Jan 2026
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High-content screening of organoids reveals the mechanisms of human pancreas acinar specification

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  DOI: 10.1016/j.stem.2025.12.023
  
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sciencedirect.com/science/article/pii/S1934590925004576
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Establishing synthetic ribbon-type active zones in a heterologous expression system

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  DOI: 10.7554/eLife.98254
  
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Dynamic S-acylation controls CMG2 maturation, extracellular matrix regulation, and anthrax toxin entry

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  DOI: 10.64898/2026.01.06.697925
  
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biorxiv.org/content/10.64898/2026.01.06.697925v1
Dec 2025
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PCSK5M452I is a recessive hypomorph exclusive to MCF10DCIS.com cells

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  DOI: 10.1158/1541-7786.MCR-25-0211
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12671455/
Sep 2025
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Protocol for isolating and characterizing extracellular vesicles by ultracentrifugation from bone marrow-derived macrophages

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  DOI: 10.1016/j.xpro.2025.104098
  
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sciencedirect.com/science/article/pii/S2666166725005040
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Seipin Governs caveolin-1 trafficking through modulating sphingolipid-glycerolipid balance

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  DOI: 10.1016/j.celrep.2025.116320
  
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The axonal ER couples translation and secretion machineries for local delivery of axonal transmembrane proteins to promote axonal development

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  DOI: 10.1101/2025.09.09.674816
  
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biorxiv.org/content/10.1101/2025.09.09.674816v1
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KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia

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  DOI: 10.1016/j.cub.2025.08.022
  
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sciencedirect.com/science/article/pii/S0960982225010887
Aug 2025
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Multiple golgins are required to support extracellular matrix secretion, modification, and assembly

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1. scibot 21 Aug 2025
  
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  DOI: 10.1083/jcb.202411167
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12360289/
Jun 2025
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ATG9A and ARFIP2 cooperate to control PI4P levels for lysosomal repair

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  DOI: 10.1016/j.devcel.2025.05.007
  
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sciencedirect.com/science/article/pii/S1534580725003181
May 2025
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ER stress disrupts insulin release in murine models of type 2 diabetes by impairing retromer action and constitutive secretion

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  DOI: 10.1016/j.celrep.2025.115691
  
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Apr 2025
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A competition network connects Rab5 and Rab11 GTPases at the surface of endocytic structures

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1. scibot 18 Apr 2025
  
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  DOI: 10.1016/j.isci.2025.112170
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11978354/
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The Chlamydia effector Dre1 binds dynactin to reposition host organelles during infection

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  DOI: 10.1016/j.celrep.2025.115509
  
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sciencedirect.com/science/article/pii/S2211124725002803
Mar 2025
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1-s2.0-S2589004225004316-main (1)-html.html

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1. scibot 13 Mar 2025
  
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  DOI: 10.24433/co.3851388.v1
  
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52.53.155.43/82b0d7e7b1f585d357ff23816b0095a55e83413f/1-s2.0-S2589004225004316-main (1)-html.html
Dec 2024
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Cell-autonomous action of Slit2 in radial migration of cortical projection neurons

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1. scibot 22 Dec 2024
  
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  DOI: 10.3389/fnmol.2024.1505434
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11646887/
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Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening

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  DOI: 10.1016/j.cels.2024.11.004
  
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sciencedirect.com/science/article/pii/S2405471224003375
Sep 2024
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S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi

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1. scibot 18 Sep 2024
  
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  DOI: 10.7554/eLife.94302
  
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elifesciences.org/articles/94302
Aug 2024
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Small GTPase ActIvitY ANalyzing (SAIYAN) system: A method to detect GTPase activation in living cells

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1. scibot 20 Aug 2024
  
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  DOI: 10.1083/jcb.202403179
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11303508/
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SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase

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1. scibot 02 Aug 2024
  
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  DOI: 10.1038/s41467-023-43027-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10640587/
Apr 2024
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NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks

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  DOI: 10.1016/j.cell.2024.03.008
  
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sciencedirect.com/science/article/pii/S0092867424003003
Mar 2024
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The IgCAM BT-IgSF (IgSF11) Is Essential for Connexin43-Mediated Astrocyte–Astrocyte Coupling in Mice

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  DOI: 10.1523/ENEURO.0283-23.2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10957231/
Jan 2024
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SARS-CoV-2 Antigen-Carrying Extracellular Vesicles Activate T Cell Responses in a Human Immunogenicity Model

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  DOI: 10.1016/j.isci.2023.108708
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10788222/
Nov 2023
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Blood flow patterns switch VEGFR2 activity through differential S-nitrosylation and S-oxidation

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  DOI: 10.1016/j.celrep.2023.113361
  
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sciencedirect.com/science/article/pii/S2211124723013736
Oct 2023
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Reduced female fertility due to sequestration of RNA Pol II by pervasive transcription in exosome RNase-depleted oocytes

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1. scibot 28 Oct 2023
  
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sciencedirect.com/science/article/pii/S2211124723012597
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The senescent secretome drives PLVAP expression in cultured human hepatic endothelial cells to promote monocyte transmigration

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  DOI: 10.1016/j.isci.2023.107966
  
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sciencedirect.com/science/article/pii/S2589004223020436
Jul 2023
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Organelle mapping in dendrites of human iPSC-derived neurons reveals dynamic functional dendritic Golgi structures

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  DOI: 10.1016/j.celrep.2023.112709
  
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sciencedirect.com/science/article/pii/S2211124723007209
May 2023
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Common Markers and Small Molecule Inhibitors in Golgi Studies

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  DOI: 10.1007/978-1-0716-2639-9_27
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10178357/
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Neurobeachin controls the asymmetric subcellular distribution of electrical synapse proteins

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  DOI: 10.1016/j.cub.2023.04.049
  
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Apr 2023
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In-depth molecular profiling of an intronic GNAO1 mutant as the basis for personalized high-throughput drug screening

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  DOI: 10.1016/j.medj.2023.03.001
  
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sciencedirect.com/science/article/pii/S2666634023000971
Mar 2023
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Secretion of VGF relies on the interplay between LRRK2 and post-Golgi v-SNAREs

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  DOI: 10.1016/j.celrep.2023.112221
  
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sciencedirect.com/science/article/pii/S2211124723002322
Feb 2023
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Synaptic vesicle proteins are selectively delivered to axons in mammalian neurons

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  DOI: 10.7554/eLife.82568
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9894587/
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CAMSAP2 localizes to the Golgi in islet β-cells and facilitates Golgi-ER trafficking

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  DOI: 10.1016/j.isci.2023.105938
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9883185/
Dec 2022
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The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities

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  DOI: 10.1007/s12035-022-03153-2
  
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link.springer.com/article/10.1007/s12035-022-03153-2
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Pyramidal neuron morphogenesis requires a septin network that stabilizes filopodia and suppresses lamellipodia during neurite initiation

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  DOI: 10.1016/j.cub.2022.11.043
  
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R17C Mutation in Photoreceptor Disc-Specific Protein, PRCD, Results in Additional Lipidation Altering Protein Stability and Subcellular Localization

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1. scibot 06 Dec 2022
  
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  DOI: 10.3390/ijms231810802
  
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52.53.155.43/80acc487fd025450db10f23a12357f3c613cec01/ijms-23-10802-v2-html.html
Nov 2022
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CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors

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1. scibot 05 Nov 2022
  
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  DOI: 10.1016/j.neuron.2022.10.018
  
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cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease

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ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains

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Self-assembly of pericentriolar material in interphase cells lacking centrioles

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Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of multiple cellular organelles during HSV-1 infection

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Extracellular vesicles from thyroid cancer harbor a functional machinery involved in extracellular matrix remodeling

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Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors

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CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development

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BARS Influences Neuronal Development by Regulation of Post-Golgi Trafficking

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Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons

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Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes

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Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates

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A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function

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Interrogating RNA and protein spatial subcellular distribution in smFISH data with DypFISH

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A Brucella effector modulates the Arf6-Rab8a GTPase cascade to promote intravacuolar replication

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High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis

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Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron Viability

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Quantification of phosphoinositides reveals strong enrichment of PIP 2 in HIV-1 compared to producer cell membranes

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Radial somatic F‐actin organization affects growth cone dynamics during early neuronal development

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Activity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network

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Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140

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RAB6 and microtubules restrict protein secretion to focal adhesions

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A Brucella Type IV Effector Targets the COG Tethering Complex to Remodel Host Secretory Traffic and Promote Intracellular Replication

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Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization

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Giantin is required for intracellular N-terminal processing of type I procollagen

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Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes

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Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers

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AKAP6 orchestrates the nuclear envelope microtubule-organizing center by linking golgi and nucleus via AKAP9

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GATA-4, a potential novel therapeutic target for high-grade meningioma, regulates miR-497, a potential novel circulating biomarker for high-grade meningioma

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Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling

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The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice

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Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo

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Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells

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  DOI: 10.1016/j.cub.2019.06.032
  
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Visualization of Protein Sorting at the Trans-Golgi Network and Endosomes Through Super-Resolution Imaging

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  DOI: 10.3389/fcell.2019.00181
  
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N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration

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A mechanism for differential sorting of the planar cell polarity proteins Frizzled6 and Vangl2 at the trans-Golgi network

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Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury

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  DOI: 10.1016/j.chom.2019.01.006
  
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Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

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The UPR Activator ATF6 Responds to Proteotoxic and Lipotoxic Stress by Distinct Mechanisms

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APC2 controls dendrite development by promoting microtubule dynamics

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GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion

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Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules

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Clptm1 Limits Forward Trafficking of GABAA Receptors to Scale Inhibitory Synaptic Strength

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Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes

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Decoding a Salmonella Typhi Regulatory Network that Controls Typhoid Toxin Expression within Human Cells

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Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer

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Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration

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Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells

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Golgi-Resident Gαo Promotes Protrusive Membrane Dynamics

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