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FLT3L-based drug conjugate effectively targets chemoresistant leukemia stem cells in acute myeloid leukemia

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1. scibot 23 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102365
  
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sciencedirect.com/science/article/pii/S2666379125004380
Jul 2025
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TAF1 is required for fetal but not adult hematopoiesis in mice

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1. scibot 17 Jul 2025
  
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  DOI: 10.1016/j.devcel.2025.06.027
  
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sciencedirect.com/science/article/pii/S1534580725004058
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NDR2 Kinase Regulate Microglial Metabolic Adaptation and Inflammatory Response: Critical Role in Glucose-Dependent Functional Plasticity

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1. scibot 12 Jul 2025
  
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  DOI: 10.1101/2025.06.12.659313
  
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biorxiv.org/content/10.1101/2025.06.12.659313v1
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PARP1-NFATc1-PD1 pathway of maturation and stability of CD8+T cells is beneficial against chronic Trypanosoma cruzi infection

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.112926
  
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sciencedirect.com/science/article/pii/S2589004225011873
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Deconstructing the intercellular interactome in vascular dementia with focal ischemia for therapeutic applications

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1. scibot 01 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.06.002
  
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cell.com/cell/fulltext/S0092-8674(25)00636-1
Apr 2025
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LAMP2A-mediated neuronal hyperexcitability by enhancing NKAβ1 degradation underlies depression-induced allodynia

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1. scibot 03 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115489
  
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sciencedirect.com/science/article/pii/S2211124725002608
Feb 2025
jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com

Inflammatory monocytes and microglia play independent roles in inflammatory ictogenesis

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1. scibot 20 Feb 2025
  
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jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-022-02394-1
Jan 2025
alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com

Roles of blood monocytes carrying TREM2R47H mutation in pathogenesis of Alzheimer's disease and its therapeutic potential in APP/PS1 mice

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1. scibot 05 Jan 2025
  
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  DOI: 10.1002/alz.14402
  
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alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.14402
May 2024
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PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages

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1. scibot 01 May 2024
  
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  DOI: 10.1016/j.celrep.2024.113942
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11022165/
Mar 2024
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Oncolytic bacteria VNP20009 expressing IFNβ inhibits melanoma progression by remodeling the tumor microenvironment

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1. scibot 22 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109372
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10951989/
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PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages

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1. scibot 15 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113942
  
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2. scibot 15 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113942
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11022165/
Nov 2023
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Investigating the role of platelets and platelet-derived transforming growth factor-β in idiopathic pulmonary fibrosis

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1. scibot 15 Nov 2023
  
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  DOI: 10.1152/ajplung.00227.2022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10639018/
Aug 2023
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CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation

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1. scibot 26 Aug 2023
  
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  DOI: 10.7554/eLife.84752
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10431918/
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Down Syndrome is Associated with Altered Frequency and Functioning of Tracheal Multiciliated Cells, and Response to Influenza Virus Infection

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1. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107361
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10405068/
Jan 2023
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METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

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1. scibot 06 Jan 2023
  
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  DOI: 10.1016/j.stem.2022.12.006
  
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sciencedirect.com/science/article/pii/S1934590922004908
Sep 2022
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Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation

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1. scibot 30 Sep 2022
  
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  DOI: 10.3389/fimmu.2022.931087
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9513153/
Aug 2022
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A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity

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1. scibot 02 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111142
  
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sciencedirect.com/science/article/pii/S2211124722009512
Jun 2022
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Mycobacterium tuberculosis infection drives a type I IFN signature in lung lymphocytes

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1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110983
  
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sciencedirect.com/science/article/pii/S2211124722007690
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Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells

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1. scibot 01 Jun 2022
  
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  DOI: 10.1016/j.cell.2022.04.039
  
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sciencedirect.com/science/article/pii/S0092867422005372
Apr 2022
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Therapeutic advantages of combined gene/cell therapy strategies in a murine model of GM2 gangliosidosis

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  DOI: 10.1016/j.omtm.2022.03.011
  
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sciencedirect.com/science/article/pii/S2329050122000419
Mar 2022
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A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis

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1. scibot 27 Mar 2022
  
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  DOI: 10.1016/j.chembiol.2022.03.006
  
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sciencedirect.com/science/article/pii/S2451945622000940
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Tumor-derived Jagged1 promotes cancer progression through immune evasion

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1. scibot 09 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110492
  
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sciencedirect.com/science/article/pii/S221112472200225X
Aug 2021
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Mds1CreERT2, an inducible Cre allele specific to adult-repopulating hematopoietic stem cells

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1. scibot 18 Aug 2021
  
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  DOI: 10.1016/j.celrep.2021.109562
  
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sciencedirect.com/science/article/pii/S2211124721009967
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Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells

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1. scibot 14 Aug 2021
  
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  DOI: 10.1016/j.ccell.2019.01.002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6645919/
May 2021
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Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.10.001
  
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sciencedirect.com/science/article/pii/S1074761320304131
Jan 2021
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Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models

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  DOI: 10.1016/j.chom.2020.12.010
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7738935/
Sep 2020
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Tumor-Derived Lactic Acid Contributes to the Paucity of Intratumoral ILC2s

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.01.103
  
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Cyto-Immuno-Therapy for Cancer: A Pathway Elicited by Tumor-Targeted, Cytotoxic Drug-Packaged Bacterially Derived Nanocells

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1. scibot 07 Sep 2020
  
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  DOI: 10.1016/j.ccell.2020.02.001
  
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sciencedirect.com/science/article/pii/S1535610820300908
Jan 2020
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Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis

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  DOI: 10.1016/j.cmet.2019.08.001
  
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sciencedirect.com/science/article/pii/S1550413119304309
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Untitled document

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  DOI: 10.1016/j.ccell.2019.01.002
  
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sciencedirect.com/science/article/pii/S1535610819300029
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Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.04.091
  
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cell.com/cell-reports/fulltext/S2211-1247(19)30571-6
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Untitled document

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  DOI: 10.1016/j.cell.2019.01.040
  
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sciencedirect.com/science/article/pii/S0092867419301035
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c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.04.090
  
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Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation

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1. scibot 12 Jan 2020
  
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  DOI: 10.1016/j.ccell.2019.04.003
  
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In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche

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Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells

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Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner

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Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors

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Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

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Untitled document

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Nov 2017
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Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6

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Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer

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Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia

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Hematopoietic Stem cell transplantation and lentiviral vector‐based gene therapy for Krabbe's disease: Present convictions and future prospects

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