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CRISPR-based functional genomics for dissecting therapeutic dependency in primary acute myeloid leukemia samples

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1. scibot 27 Feb 2026
  
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  DOI: 10.1016/j.molcel.2026.02.003
  
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sciencedirect.com/science/article/pii/S1097276526000985
Feb 2026
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Platelets as immune sensors: monitoring immune dynamics and diagnosing disease states across multiple disorders

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.ebiom.2026.106174
  
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sciencedirect.com/science/article/pii/S2352396426000551
Jan 2026
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Tunable differentiation of human CD4+ and CD8+ T cells from pluripotent stem cells

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.stem.2025.12.010
  
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cell.com/cell-stem-cell/fulltext/S1934-5909(25)00444-8
Oct 2025
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CXCL10-induced chemotaxis of ex vivo-expanded natural killer cells combined with NKTR-255 enhances anti-tumor efficacy in osteosarcoma

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1. scibot 01 Oct 2025
  
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  DOI: 10.1016/j.omton.2025.201051
  
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sciencedirect.com/science/article/pii/S2950329925001201
Sep 2025
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Characterization of human CD34+ HSPC-derived neutrophils with limited myeloid-derived immunosuppressive cell activity

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1. scibot 25 Sep 2025
  
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  DOI: 10.1016/j.isci.2025.113404
  
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sciencedirect.com/science/article/pii/S2589004225016657
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Genetic Screen in a Pre-Clinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities

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1. scibot 16 May 2025
  
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  DOI: 10.1158/1078-0432.CCR-24-1238
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11530313/
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Proteogenomic reprogramming to a functional human blastomere-like stem cell state via a PARP-DUX4 regulatory axis

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115671
  
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sciencedirect.com/science/article/pii/S2211124725004425
Feb 2025
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C/EBPa confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia

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1. scibot 14 Feb 2025
  
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aacrjournals.org/cancerdiscovery/article/13/7/1720/727640/C-EBP-Confers-Dependence-to-Fatty-Acid-Anabolic
Jan 2025
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Contrasting cytotoxic and regulatory T cell responses underlying distinct clinical outcomes to anti-PD-1 plus lenvatinib therapy in cancer

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1. scibot 31 Jan 2025
  
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  DOI: 10.1016/j.ccell.2025.01.001
  
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sciencedirect.com/science/article/pii/S1535610825000194
Dec 2024
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B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies

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sciencedirect.com/science/article/pii/S235239642400495X
Jul 2024
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Disruption of TGF-β signaling pathway is required to mediate effective killing of hepatocellular carcinoma by human iPSC-derived NK cells

2
1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.stem.2024.06.009
  
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2. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.stem.2024.06.009
  
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cell.com/cell-stem-cell/abstract/S1934-5909(24)00217-0
Apr 2024
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Pyroptotic T cell-derived active IL-16 has a driving function in ovarian endometriosis development

1
1. scibot 03 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101476
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10983113/
Dec 2023
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AA2P-mediated DNA demethylation synergizes with stem cell agonists to promote expansion of hematopoietic stem cells

3
1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.crmeth.2023.100663
  
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2. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.crmeth.2023.100663
  
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sciencedirect.com/science/article/pii/S2667237523003405
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Identification of druggable regulators of cell secretion via a kinome-wide screen and high-throughput immunomagnetic cell sorting

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1. scibot 02 Dec 2023
  
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  DOI: 10.1038/s41551-023-01135-w
  
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link.springer.com/article/10.1038/s41551-023-01135-w
Jul 2023
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Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response

4
1. scibot 29 Jul 2023
  
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  DOI: 10.7554/eLife.85875
  
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2. scibot 29 Jul 2023
  
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  DOI: 10.7554/eLife.85875
  
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3. scibot 29 Jul 2023
  
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  DOI: 10.7554/eLife.85875
  
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4. scibot 29 Jul 2023
  
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  DOI: 10.7554/eLife.85875
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10371228/
52.53.155.43 52.53.155.43

cd-22-0411-html.html

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  DOI: 10.1158/2159-8290.CD-22-0411
  
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52.53.155.43/453457acda6208aed297e8061921a5c2d2ddddf2/cd-22-0411-html.html
Dec 2022
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Chemically defined generation of human definitive hematopoietic stem and progenitor cells

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1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.xpro.2022.101953
  
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sciencedirect.com/science/article/pii/S2666166722008334
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Integrative RNA-omics discovers GNAS alternative splicing as a phenotypic driver of splicing factor-mutant neoplasms

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  DOI: 10.1158/2159-8290.CD-21-0508
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8904276/
Jul 2022
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Engineering chimeric antigen receptor neutrophils from human pluripotent stem cells for targeted cancer immunotherapy

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111128
  
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sciencedirect.com/science/article/pii/S2211124722009342
Apr 2022
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Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells

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1. scibot 27 Apr 2022
  
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  DOI: 10.1016/j.celrep.2022.110752
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9099058/
Mar 2022
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Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function

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  DOI: 10.1016/j.stem.2022.02.010
  
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sciencedirect.com/science/article/pii/S1934590922000613
Jan 2022
diabetesjournals.org diabetesjournals.org

Diabetes With Multiple Autoimmune and Inflammatory Conditions Linked to an Activating SKAP2 Mutation

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1. scibot 28 Jan 2022
  
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  DOI: 10.2337/dc20-2317
  
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diabetesjournals.org/care/article/44/8/1816/138875/Diabetes-With-Multiple-Autoimmune-and-Inflammatory
May 2021
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Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets

1
1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2021.01.011
  
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sciencedirect.com/science/article/pii/S1934590921000114
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Lack of mucosal cholinergic innervation is associated with increased risk of enterocolitis in Hirschsprung’s disease

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  DOI: 10.1016/j.jcmgh.2021.03.004
  
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cmghjournal.org/article/S2352-345X(21)00056-4/abstract
Apr 2021
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Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia

1
1. scibot 17 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.05.014
  
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sciencedirect.com/science/article/pii/S1535610820302646
Feb 2021
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Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma

1
1. scibot 27 Feb 2021
  
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  DOI: 10.1016/j.cell.2020.11.041
  
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sciencedirect.com/science/article/pii/S0092867420316135
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The effects of moderate and high intensity exercise on circulating markers of endothelial integrity and activation in young, healthy men

1
1. scibot 24 Feb 2021
  
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  DOI: 10.1152/japplphysiol.00477.2019
  
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physiology.org/doi/abs/10.1152/japplphysiol.00477.2019
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hESC-derived immune suppressive dendritic cells induce immune tolerance of parental hESC-derived allografts

1
1. scibot 24 Feb 2021
  
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  RRID:AB_398
  
  DOI: 10.1016/j.ebiom.2020.103120
  
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sciencedirect.com/science/article/pii/S2352396420304965
Jan 2021
www.nature.com www.nature.com

Stem-cell-derived human microglia transplanted into mouse brain to study human disease

1
1. scibot 20 Jan 2021
  
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  DOI: 10.1038/s41596-020-00447-4
  
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nature.com/articles/s41596-020-00447-4
Nov 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The effects of moderate and high-intensity exercise on circulating markers of endothelial integrity and activation in young, healthy men

1
1. scibot 05 Nov 2020
  
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  DOI: 10.1152/japplphysiol.00477.2019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6879831/
Oct 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma

1
1. scibot 13 Oct 2020
  
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  anti-CD45 APC
  
  DOI: 10.1016/j.ebiom.2020.103031
  
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pubmed.ncbi.nlm.nih.gov/33045471/
Sep 2020
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Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells

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1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107688
  
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LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation

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1. scibot 14 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107600
  
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Nov 2018
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Photobiomodulation of mesenchymal stem cells encapsulated in an injectable rhBMP4‐loaded hydrogel directs hard tissue bioengineering

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1. scibot 05 Nov 2018
  
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onlinelibrary.wiley.com/doi/10.1002/jcp.26309/full
Nov 2017
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Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia

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1. scibot 08 Nov 2017
  
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