186 Matching Annotations
  1. Last 7 days
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    Relationship between inner hair cell synaptopathy and outer hair cell loss in two mouse models of accelerated age-related hearing loss
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    sciencedirect.com/science/article/pii/S019745802500137X
  3. Aug 2025
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    Protocol for assessing auditory function, cochlear synaptopathy, and afferent terminal morphology in laboratory mice
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    sciencedirect.com/science/article/pii/S2666166725004460
  5. Jul 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Strengthening Medial Olivocochlear Feedback Reduces the Developmental Impact of Early Noise Exposure
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    pmc.ncbi.nlm.nih.gov/articles/PMC12236841/
  7. Jun 2025
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    A genome-wide in vivo CRISPR screen identifies neuroprotective strategies in the mouse and human retina
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148056/
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    Cochlear gene therapy restores hearing and auditory processing in an atypical DFNB9 mouse model
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    nature.com/articles/s43856-025-00926-3
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    Combinatorial transcriptional regulation establishes subtype-appropriate synaptic properties in auditory neurons
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    sciencedirect.com/science/article/pii/S2211124725005674
  11. May 2025
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    Single-nucleus profiling of mouse inner ear aging uncovers cell type heterogeneity and hair cell subtype-specific age-related signatures
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    sciencedirect.com/science/article/pii/S2211124725005522
  13. Apr 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular mechanism establishing the OFF pathway in vision
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    pmc.ncbi.nlm.nih.gov/articles/PMC12008213/
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  16. Mar 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Eye features and retinal photoreceptors of the nocturnal aardvark (Orycteropus afer, Tubulidentata)
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    pmc.ncbi.nlm.nih.gov/articles/PMC11932471/
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    1-s2.0-S2589004225004626-main-html.html
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  19. Feb 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ERG responses to high-frequency flickers require FAT3 signaling in mouse retinal bipolar cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11793021/
  21. Jan 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Resistance to age-related hearing loss in the echolocating big brown bat (Eptesicus fuscus)
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    pmc.ncbi.nlm.nih.gov/articles/PMC11708781/
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    1-s2.0-S2589004225000598-main-html.html
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    Placode and neural crest origins of congenital deafness in mouse models of Waardenburg-Shah syndrome
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    sciencedirect.com/science/article/pii/S2589004224029079
  25. Dec 2024
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11668525/
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    Repeated low-intensity noise exposure exacerbates age-related hearing loss via RAGE signaling pathway
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    sciencedirect.com/science/article/pii/S096999612400370X
  28. Nov 2024
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Local delivery of soluble fractalkine (CX3CL1) peptide restores ribbon synapses after noise-induced cochlear synaptopathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11557324/
  30. Sep 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11392653/
  32. Aug 2024
  33. www.sciencedirect.com www.sciencedirect.com
    Reorganization of H3K9me heterochromatin leads to neuronal impairment via the cascading destruction of the KDM3B-centered epigenomic network
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    sciencedirect.com/science/article/pii/S2589004224016055
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    Somatic and neuritic spines on tyrosine hydroxylase–immunopositive cells of rat retina
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    onlinelibrary.wiley.com/doi/10.1002/cne.24166/full
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    Expression and cellular localization of the voltage‐gated calcium channel α2δ3 in the rodent retina
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    onlinelibrary.wiley.com/doi/10.1002/cne.23751/full
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    Large basolateral processes on type II hair cells are novel processing units in mammalian vestibular organs
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    onlinelibrary.wiley.com/doi/10.1002/cne.23625/full
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    Melanopsin expressing human retinal ganglion cells: Subtypes, distribution, and intraretinal connectivity
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    onlinelibrary.wiley.com/doi/10.1002/cne.24181/full
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    Brn3a and Brn3b knockout mice display unvaried retinal fine structure despite major morphological and numerical alterations of ganglion cells
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    onlinelibrary.wiley.com/doi/10.1002/cne.24072/full
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    Morphology and connectivity of the small bistratified A8 amacrine cell in the mouse retina
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    onlinelibrary.wiley.com/doi/10.1002/cne.23752/full
  40. Jul 2024
  41. www.biorxiv.org www.biorxiv.org
    Resistance to age-related hearing loss in the echolocating big brown bat (Eptesicus fuscus)
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    biorxiv.org/content/10.1101/2024.07.15.603592v1
  42. www.science.org www.science.org
    In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss
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    science.org/doi/10.1126/sciadv.adk2299
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dye coupling of horizontal cells in the primate retina
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    ncbi.nlm.nih.gov/pmc/articles/PMC11182241/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for in vivo elimination of avian auditory hair cells, multiplexed mRNA detection, immunohistochemistry, and S-phase labeling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11217775/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    From hidden hearing loss to supranormal auditory processing by neurotrophin 3-mediated modulation of inner hair cell synapse density
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    ncbi.nlm.nih.gov/pmc/articles/PMC11210788/
  46. Jun 2024
  47. www.science.org www.science.org
    In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss
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    science.org/doi/10.1126/sciadv.adk2299
  48. May 2024
  49. 52.53.155.43 52.53.155.43
    Lateral olivocochlear neurons modulate cochlear responses to noise exposure
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    52.53.155.43/32f802f3a736a5052551785d31c727d7afc3a089/2024.03.04.583418v1.full-html.html
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    Age-related deficits in binaural hearing: Contribution of peripheral and central effects
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    jneurosci.org/content/44/16/e0963222024
  51. Apr 2024
  52. www.sciencedirect.com www.sciencedirect.com
    Necl-1/CADM3 regulates cone synapse formation in the mouse retina
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    sciencedirect.com/science/article/pii/S2589004224007995
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    BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing
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    sciencedirect.com/science/article/pii/S221112472400353X
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    Extrasynaptic distribution of NMDA receptors in cochlear inner hair cell afferent signaling complex
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    sciencedirect.com/science/article/pii/S0891061824000309
  55. Mar 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The deubiquitinase Otud7b suppresses cone photoreceptor degeneration in mouse models of retinal degenerative diseases
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    ncbi.nlm.nih.gov/pmc/articles/PMC10951987/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cochlear Ribbon Synapses in Aged Gerbils
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    ncbi.nlm.nih.gov/pmc/articles/PMC10931817/
  58. Feb 2024
  59. www.biorxiv.org www.biorxiv.org
    Female mice lacking GluA3 show early onset of hearing loss, synaptopathy, and afferent swellings in ambient sound levels
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    biorxiv.org/content/10.1101/2024.02.21.581467v1
  60. www.biorxiv.org www.biorxiv.org
    Local Delivery of Soluble Fractalkine (CX3CL1) Peptide Restore Ribbon Synapses After Noise-Induced Cochlear Synaptopathy
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    biorxiv.org/content/10.1101/2024.02.20.581182v1
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    JNEUROSCI.0963-22.2024.full-html.html
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    Hair cell regeneration, reinnervation, and restoration of hearing thresholds in the avian hearing organ
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    sciencedirect.com/science/article/pii/S2211124724001505
  63. iovs.arvojournals.org iovs.arvojournals.org
    Targeted Expression of Anoctamin Calcium-Activated Chloride Channels in Rod Photoreceptor Terminals of the Rodent Retina
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    iovs.arvojournals.org/article.aspx
  64. www.mdpi.com www.mdpi.com
    Oxidative Stress Plays an Important Role in Glutamatergic Excitotoxicity-Induced Cochlear Synaptopathy: Implication for Therapeutic Molecules Screening
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    mdpi.com/2076-3921/13/2/149
  65. Jan 2024
  66. www.jneurosci.org www.jneurosci.org
    βII-Spectrin Is Required for Synaptic Positioning during Retinal Development
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    jneurosci.org/content/43/29/5277
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  68. Dec 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nfia is Critical for AII Amacrine Cell Production: Selective Bipolar Cell Dependencies and Diminished ERG
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    ncbi.nlm.nih.gov/pmc/articles/PMC10711738/
  71. Oct 2023
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Absence of Embigin accelerates hearing loss and causes sub-viability, brain and cardiac defects in C57BL/6N mice due to interaction with Cdh23ahl
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    pmc.ncbi.nlm.nih.gov/articles/PMC10579432/
  73. www.biorxiv.org www.biorxiv.org
    Auditory Hair Cells and Spiral Ganglion Neurons Regenerate Synapses with Refined Release Properties In Vitro
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    biorxiv.org/content/10.1101/2023.10.05.561095v1
  74. Sep 2023
  75. www.mdpi.com www.mdpi.com
    Functional, Morphological and Molecular Changes Reveal the Mechanisms Associated with Age-Related Vestibular Loss
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mTORC2 regulates auditory hair cell structure and function
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    Loss of synaptic ribbons is an early cause in ROS-induced acquired sensorineural hearing loss
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  78. Aug 2023
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large-scale survey of excitatory synapses reveals sublamina-specific and asymmetric synapse patterns in a neurodegenerative circuit
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    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
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  81. Jun 2023
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    Accelerated evolution analysis uncovers PKNOX2 as a key transcription factor in the mammalian cochlea
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    52.53.155.43/aa0ce732db85edd35d07cb9d4ff03b663dcc6ac3/msad128-html.html
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    Macrophages Promote Repair of Inner Hair Cell Ribbon Synapses Following Noise-Induced Cochlear Synaptopathy
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    jneurosci.org/content/43/12/2075
  84. May 2023
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Round-window delivery of lithium chloride regenerates cochlear synapses damaged by noise-induced excitotoxic trauma via inhibition of the NMDA receptor in the rat
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    ncbi.nlm.nih.gov/pmc/articles/PMC10202264/
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    The vestibular calyceal junction is dismantled following subchronic streptomycin in rats and sensory epithelium stress in humans
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    link.springer.com/article/10.1007/s00204-023-03518-z
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mouse all-cone retina models of Cav1.4 synaptopathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10174292/
  88. www.sciencedirect.com www.sciencedirect.com
    Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development
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    sciencedirect.com/science/article/pii/S2211124723005156
  89. www.science.org www.science.org
    A disease-associated mutation in thyroid hormone receptor α1 causes hearing loss and sensory hair cell patterning defects in mice
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    science.org/doi/10.1126/scisignal.abj4583
  90. www.biorxiv.org www.biorxiv.org
    Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis
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    biorxiv.org/content/10.1101/2023.04.26.538373v1
  91. Apr 2023
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa
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    ncbi.nlm.nih.gov/pmc/articles/PMC10104154/
  93. Feb 2023
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative trait loci on chromosomes 9 and 19 modulate AII amacrine cell number in the mouse retina
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    ncbi.nlm.nih.gov/pmc/articles/PMC9932814/
  95. www.sciencedirect.com www.sciencedirect.com
    Runx1 controls auditory sensory neuron diversity in mice
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    sciencedirect.com/science/article/pii/S1534580723000394
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses
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    ncbi.nlm.nih.gov/pmc/articles/PMC9908081/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GluA3 subunits are required for appropriate assembly of AMPAR GluA2 and GluA4 subunits on cochlear afferent synapses and for presynaptic ribbon modiolar–pillar morphology
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    ncbi.nlm.nih.gov/pmc/articles/PMC9891727/
  98. Jan 2023
  99. journals.lww.com journals.lww.com
    PTEN inhibitor bisperoxovanadium protects against... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/07000/PTEN_inhibitor_bisperoxovanadium_protects_against.36.aspx
  100. Dec 2022
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses
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    ncbi.nlm.nih.gov/pmc/articles/PMC9722480/
  102. elifesciences.org elifesciences.org
    Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals
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    elifesciences.org/articles/79712
  103. Oct 2022
  104. www.sciencedirect.com www.sciencedirect.com
    Synaptotagmins 1 and 7 in vesicle release from rods of mouse retina
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    sciencedirect.com/science/article/pii/S0014483522003608
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Noise-induced hearing loss vulnerability in type III intermediate filament peripherin gene knockout mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9549866/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental errors in the common marmoset retina
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    ncbi.nlm.nih.gov/pmc/articles/PMC9531312/
  107. Sep 2022
  108. www.sciencedirect.com www.sciencedirect.com
    Post-developmental plasticity of the primary rod pathway allows restoration of visually guided behaviors
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    sciencedirect.com/science/article/pii/S0960982222014609
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    No evidence for age-related alterations in the marmoset retina
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    ncbi.nlm.nih.gov/pmc/articles/PMC9479465/
  110. Aug 2022
  111. www.sciencedirect.com www.sciencedirect.com
    Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3
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    sciencedirect.com/science/article/pii/S2589004222010756
  112. Jul 2022
  113. www.researchsquare.com www.researchsquare.com
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    Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism
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    sciencedirect.com/science/article/pii/S2589004222008975
  115. Jun 2022
  116. 52.53.155.43 52.53.155.43
    A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation.
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    52.53.155.43/e4d43df84a4c01101d4a56f054b21f9c50836051/1-s2.0-S2589004222008525-main-html.html
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of noise exposure and aging on behavioral tone detection in quiet and noise by mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9191765/
  118. Mar 2022
  119. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell numbers, cell ratios, and developmental plasticity in the rod pathway of the mouse retina
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    Morphology and connectivity of the small bistratified A8 amacrine cell in the mouse retina
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    onlinelibrary.wiley.com/doi/10.1002/cne.23752/full
  228. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Postnatal Expression of Neurotrophic Factors Accessible to Spiral Ganglion Neurons in the Auditory System of Adult Hearing and Deafened Rats
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    ncbi.nlm.nih.gov/pmc/articles/PMC4172804/