156 Matching Annotations
  1. Sep 2024
  2. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 28 Sep 2024
      RRID:AB_430833

      DOI: 10.1111/bph.17312

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17312
  3. elifesciences.org elifesciences.org
    Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axis
    1
    1. scibot 28 Sep 2024
      RRID:AB_430833

      DOI: 10.7554/eLife.97662

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    elifesciences.org/articles/97662
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clearing the JUNQ: the molecular machinery for sequestration, localization, and degradation of the JUNQ compartment
    1
    1. scibot 12 Sep 2024
      RRID:AB_430833

      DOI: 10.3389/fmolb.2024.1427542

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    ncbi.nlm.nih.gov/pmc/articles/PMC11372896/
  5. Aug 2024
  6. www.sciencedirect.com www.sciencedirect.com
    RNA interacts with topoisomerase I to adjust DNA topology
    1
    1. scibot 23 Aug 2024
      AB_430833

      DOI: 10.1016/j.molcel.2024.07.032

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    sciencedirect.com/science/article/pii/S1097276524006300
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks
    1
    1. scibot 21 Aug 2024
      RRID:AB_430833

      DOI: 10.1038/s41388-024-03094-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11315672/
  8. Jul 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain
    1
    1. scibot 19 Jul 2024
      RRID:AB_430833

      DOI: 10.1016/j.cell.2024.05.058

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    sciencedirect.com/science/article/pii/S0092867424006391
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin Potentiates JAK/STAT Signaling to Broadly Inhibit Flavivirus Replication in Insect Vectors
    1
    1. scibot 11 Jul 2024
      RRID:AB_430833

      DOI: 10.1016/j.celrep.2019.10.029

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    ncbi.nlm.nih.gov/pmc/articles/PMC6871768/
  11. Jun 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMAD4 promotes somatic-germline contact during murine oocyte growth
    1
    1. scibot 04 Jun 2024
      RRID:AB_430833

      DOI: 10.7554/eLife.91798

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    ncbi.nlm.nih.gov/pmc/articles/PMC11142639/
  13. Apr 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Exogenous non-coding dsDNA-dependent trans-activation of phagocytes augments anti-tumor immunity
    1
    1. scibot 30 Apr 2024
      RRID:AB_430833

      DOI: 10.1016/j.xcrm.2024.101528

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    sciencedirect.com/science/article/pii/S2666379124001976
  15. www.sciencedirect.com www.sciencedirect.com
    Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells
    1
    1. scibot 26 Apr 2024
      RRID:AB_430833

      DOI: 10.1016/j.xcrm.2024.101526

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    sciencedirect.com/science/article/pii/S2666379124001952
  16. www.sciencedirect.com www.sciencedirect.com
    S1PR3 agonism and S1P lyase inhibition rescue mice in the severe state of experimental sepsis
    1
    1. scibot 12 Apr 2024
      Promega, Walldorf, Germany, #W4011

      DOI: 10.1016/j.biopha.2024.116575

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    sciencedirect.com/science/article/pii/S0753332224004591
  17. Mar 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Doxorubicin‑induced cardiomyopathy is mitigated by empagliflozin via the modulation of endoplasmic reticulum stress pathways
    1
    1. scibot 27 Mar 2024
      RRID:AB_430833

      DOI: 10.3892/mmr.2024.13198

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    ncbi.nlm.nih.gov/pmc/articles/PMC10958136/
  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regional modulation of toll-like receptor signaling pathway genes in acute epididymitis in mice
    1
    1. scibot 26 Mar 2024
      RRID:AB_430833

      DOI: 10.1111/andr.13630

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    onlinelibrary.wiley.com/doi/10.1111/andr.13630
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depletion of SMN protein in mesenchymal progenitors impairs the development of bone and neuromuscular junction in spinal muscular atrophy
    1
    1. scibot 23 Mar 2024
      RRID:AB_430833

      DOI: 10.7554/eLife.92731

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    ncbi.nlm.nih.gov/pmc/articles/PMC10945524/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineered FSHD mutations results in D4Z4 heterochromatin disruption and feedforward DUX4 network activation
    1
    1. scibot 22 Mar 2024
      RRID:AB_430833

      DOI: 10.1016/j.isci.2024.109357

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951985/
  22. 52.53.155.43 52.53.155.43
    TORC1 is an essential regulator of nutrient-controlled proliferation and differentiation in Leishmania
    3
    1. scibot 21 Mar 2024
      RRID:AB_430833

      DOI: 10.1038/s44319-024-00084-y

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    2. scibot 21 Mar 2024
      RRID:AB_430833

      DOI: 10.1038/s44319-024-00084-y

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    3. scibot 16 Mar 2024
      RRID:AB_430833

      DOI: 10.1038/s44319-024-00084-y

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    52.53.155.43/7141871f0013a4bcb963eeace4dd2a37f4c5d4d5/myburgh-et-al-2024-torc1-is-an-essential-regulator-of-nutrient-controlled-proliferation-and-differentiation-in-html.html
  23. www.sciencedirect.com www.sciencedirect.com
    PABPC1 mediates degradation of C9orf72-FTLD/ALS GGGGCC repeat RNA
    1
    1. scibot 08 Mar 2024
      PromegaCat# W401B

      DOI: 10.1016/j.isci.2024.109303

      Resource: (Promega Cat# W4011, RRID:AB_430833)

      Curator: @abever99

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    sciencedirect.com/science/article/pii/S2589004224005248
  24. www.sciencedirect.com www.sciencedirect.com
    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
    3
    1. scibot 01 Mar 2024
      RRID:AB_430833

      DOI: 10.1016/j.ccell.2024.02.004

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    2. scibot 01 Mar 2024
      RRID:AB_430833

      DOI: 10.1016/j.ccell.2024.02.004

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    3. scibot 01 Mar 2024
      RRID:AB_430833

      DOI: 10.1016/j.ccell.2024.02.004

      Resource: (Promega Cat# W4011, RRID:AB_430833)

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    sciencedirect.com/science/article/pii/S1535610824000485
  25. Feb 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1
    1
    1. scibot 27 Feb 2024
      PromegaW401B

      DOI: 10.1016/j.celrep.2024.113837

      Resource: (Promega Cat# W4011, RRID:AB_430833)

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    sciencedirect.com/science/article/pii/S2211124724001657
  27. Jan 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Parallel control of cold-triggered adipocyte thermogenesis by UCP1 and CKB
    1
    1. scibot 25 Jan 2024
      RRID:AB_430833

      DOI: 10.1016/j.cmet.2024.01.001

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    sciencedirect.com/science/article/pii/S1550413124000019
  29. www.sciencedirect.com www.sciencedirect.com
    Recruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B
    1
    1. scibot 11 Jan 2024
      RRID: 430833

      DOI: 10.1016/j.molcel.2023.12.011

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    sciencedirect.com/science/article/pii/S1097276523010304
  30. www.sciencedirect.com www.sciencedirect.com
    Rapamycin-sensitive mechanisms confine the growth of fission yeast below the temperatures detrimental to cell physiology
    1
    1. scibot 11 Jan 2024
      RRID:AB_430833

      DOI: 10.1016/j.isci.2023.108777

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    sciencedirect.com/science/article/pii/S2589004223028547
  31. Oct 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion
    1
    1. scibot 28 Oct 2023
      RRID:AB_430833

      DOI: 10.1016/j.celrep.2023.113275

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    sciencedirect.com/science/article/pii/S2211124723012871
  33. Sep 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Identification of genes required for Plasmodium gametocyte-to-sporozoite development in the mosquito vector
    1
    1. scibot 16 Sep 2023
      RRID:AB_430833

      DOI: 10.1016/j.chom.2023.08.010

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    sciencedirect.com/science/article/pii/S1931312823003359
  35. Aug 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A stepwise and digital pattern of RSK phosphorylation determines the outcome of thymic selection
    1
    1. scibot 31 Aug 2023
      RRID:AB_430833

      DOI: 10.1016/j.isci.2023.107552

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    ncbi.nlm.nih.gov/pmc/articles/PMC10460994/
  37. www.biorxiv.org www.biorxiv.org
    Acylation of MLKL impacts its function in necroptosis
    1
    1. scibot 28 Aug 2023
      RRID:AB_430833

      DOI: 10.1101/2023.08.19.553906

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    biorxiv.org/content/10.1101/2023.08.19.553906v1
  38. Jul 2023
  39. 52.53.155.43 52.53.155.43
    Paracingulin recruits CAMSAP3 to tight junctions and regulates microtubule and polarized epithelial organization
    1
    1. scibot 02 Jul 2023
      RRID:AB_430833

      DOI: 10.1242/jcs.260745

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    52.53.155.43/84cf2b7dc60eecb18bb52883e6904f2535d498be/jcs260745supp-html.html
  40. Jun 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts
    1
    1. scibot 29 Jun 2023
      RRID:AB_430833

      DOI: 10.1016/j.isci.2023.107113

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    sciencedirect.com/science/article/pii/S2589004223011902
  42. www.sciencedirect.com www.sciencedirect.com
    An EZH2-NF-κB Regulatory Axis Drives Expression of Pro-Oncogenic Gene Signatures in Triple Negative Breast Cancer
    1
    1. scibot 27 Jun 2023
      RRID:AB_430833

      DOI: 10.1016/j.isci.2023.107115

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    sciencedirect.com/science/article/pii/S2589004223011926
  43. www.embopress.org www.embopress.org
    PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems
    1
    1. scibot 23 Jun 2023
      RRID:AB_430833

      DOI: 10.15252/embr.202256399

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    embopress.org/doi/full/10.15252/embr.202256399
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TL-532, a novel specific Toll-like receptor 3 agonist rationally designed for targeting cancers: discovery process and biological characterization
    1
    1. scibot 07 Jun 2023
      RRID:AB_430833

      DOI: 10.15698/mic2023.06.797

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    ncbi.nlm.nih.gov/pmc/articles/PMC10236204/
  45. www.sciencedirect.com www.sciencedirect.com
    Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α
    1
    1. scibot 02 Jun 2023
      RRID:AB_430833

      DOI: 10.1016/j.molcel.2023.05.008

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    sciencedirect.com/science/article/pii/S1097276523003325
  46. May 2023
  47. www.sciencedirect.com www.sciencedirect.com
    FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation
    1
    1. scibot 20 May 2023
      RRID:AB_430833

      DOI: 10.1016/j.celrep.2023.112530

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    sciencedirect.com/science/article/pii/S2211124723005417
  48. www.sciencedirect.com www.sciencedirect.com
    16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice
    1
    1. scibot 11 May 2023
      RRID:AB_430833

      DOI: 10.1016/j.celrep.2023.112485

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    sciencedirect.com/science/article/pii/S2211124723004965
  49. www.sciencedirect.com www.sciencedirect.com
    HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways
    1
    1. scibot 11 May 2023
      RRID:AB_430833

      DOI: 10.1016/j.celrep.2023.112496

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    sciencedirect.com/science/article/pii/S2211124723005077
  50. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Group IVE cytosolic phospholipase A2 limits psoriatic inflammation by mobilizing the anti-inflammatory lipid N-acylethanolamine
    1
    1. scibot 05 May 2023
      RRID:AB_430833

      DOI: 10.1096/fj.202101958R

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      Curator: @a5munoz

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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202101958R
  51. Apr 2023
  52. academic.oup.com academic.oup.com
    Neuronal blockade of thyroid hormone signaling increases sensitivity to diet-induced obesity in adult male mice
    1
    1. scibot 21 Apr 2023
      RRID:AB_430833

      DOI: 10.1210/endocr/bqad034

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    Preclinical Evidence of Progesterone as a New Pharmacological Strategy in Human Adrenocortical Carcinoma Cell Lines
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  55. Mar 2023
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    Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer
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    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
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    CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis
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    Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues
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    Combined control of the fibroblast contractile program by YAP and TAZ
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    Exclusion of m6A from splice-site proximal regions by the exon junction complex dictates m6A topologies and mRNA stability
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    Preclinical evidence of progesterone as a new pharmacological strategy in human adrenocortical carcinoma cell lines
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    Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence
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    Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis
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  71. Oct 2022
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    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
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    FBXL6 depletion restrains clear cell renal cell carcinoma progression
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    Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages
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  76. Aug 2022
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    Protocol for the generation of HIV-1 genomic RNA with altered levels of N6-methyladenosine
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    Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism
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    Amino acid catabolism regulates hematopoietic stem cell proteostasis via a GCN2-eIF2α axis
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    The granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin
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    ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer
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    Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements
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    VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites
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  96. Jan 2022
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  103. Oct 2021
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    Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy
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  106. Sep 2021
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    Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition
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    Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition
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    A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to Promote α-Toxin Cytotoxicity
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    IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and Mitochondrial Homeostasis
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  118. Jul 2021
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    Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas
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    PKA phosphorylation underlies functional recruitment of sarcolemmal SK2 channels in ventricular myocytes from hypertrophic hearts
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    A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to Promote α-Toxin Cytotoxicity
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    CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity
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  124. Jun 2021
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    Surface AMP deaminase 2 as a novel regulator modifying extracellular adenine nucleotide metabolism
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    Ultracentrifugal separation, characterization, and functional study of extracellular vesicles derived from serum-free cell culture
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    Targeting ribosomal G-quadruplexes with naphthalene-diimides as RNA polymerase I inhibitors for colorectal cancer treatment
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  128. May 2021
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    Prenatal treatment with rapamycin restores enhanced hippocampal mGluR-LTD and mushroom spine size in a Down’s syndrome mouse model
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  130. journals.plos.org journals.plos.org
    The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism
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    Disease-causing mutated ATLASTIN 3 is excluded from distal axons and reduces axonal autophagy
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    Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells
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    The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis
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    Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells
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    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
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    NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate
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    Low expression of the PPARγ-regulated gene thioredoxin-interacting protein accompanies human melanoma progression and promotes experimental lung metastases
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    The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming
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    Protein acylation by saturated very long chain fatty acids and endocytosis are involved in necroptosis
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  144. Mar 2021
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  146. Feb 2021
  147. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Tissue‐specific deletion of mouse basolateral uniporter LAT4 (Slc43a2) reveals its crucial role in small intestine and kidney amino acid transport
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    Amelioration of elastase‐induced lung emphysema and reversal of pulmonary hypertension by pharmacological iNOS inhibition in mice
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    Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase
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    The autism-related protein CHD8 contributes to the stemness and differentiation of mouse hematopoietic stem cells
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  152. Jan 2021
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    Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders
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  154. Dec 2020
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    Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene
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  156. Nov 2020
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    PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage
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  158. Sep 2020
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    Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing
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    Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway
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    A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging
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    Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction
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      DOI: 10.1523/JNEUROSCI.0893-19.2020

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    Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling
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    Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription
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  165. journals.plos.org journals.plos.org
    Phosphorylation of mouse intestinal basolateral amino acid uniporter LAT4 is controlled by food-entrained diurnal rhythm and dietary proteins
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    A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells
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    Liquidity Is a Critical Determinant for Selective Autophagy of Protein Condensates
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  168. Jan 2020
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    The Translational Landscape of the Human Heart
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  170. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Prothymosin alpha and its mimetic hexapeptide improve delayed tPA‐induced brain damage following cerebral ischemia
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    Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb
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    Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin Potentiates JAK/STAT Signaling to Broadly Inhibit Flavivirus Replication in Insect Vectors
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    YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression
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  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    tRNA ligase structure reveals kinetic competition between non-conventional mRNA splicing and mRNA decay
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    MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes
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  177. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2018.12.017

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  179. Nov 2018
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  181. f1000research.com f1000research.com
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    Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function
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    Atypical Cadherin Dachsous1b Interacts with Ttc28 and Aurora B to Control Microtubule Dynamics in Embryonic Cleavages
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    Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells
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    APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway
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    Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics
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    Very Long Chain Fatty Acids Are Functionally Involved in Necroptosis
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  191. Nov 2017
  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors
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    Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles
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    ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation
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  195. elifesciences.org elifesciences.org
    The novel SH3 domain protein Dlish/CG10933 mediates fat signaling in Drosophila by binding and regulating Dachs
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Granulin Knock Out Zebrafish Lack Frontotemporal Lobar Degeneration and Neuronal Ceroid Lipofuscinosis Pathology
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