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Systematic CRISPR screens decode regulators of primary human pathogenic Th17 cell differentiation and activation

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1. scibot 14 Nov 2026
  
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  DOI: 10.1016/j.isci.2026.118180
  
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sciencedirect.com/science/article/pii/S2589004226035637
Jul 2026
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Immunotherapy-based combination remodels the immunosuppressive microenvironment and enhances efficacy in advanced SMARCA4-deficient non-small cell lung cancer

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1. scibot 07 Jul 2026
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.canlet.2026.218702
  
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sciencedirect.com/science/article/pii/S0304383526004660
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Extracellular ATP-P2RY2 signaling drives intratumoral prostaglandin E2 accumulation and adaptive resistance to immunotherapy in solid tumors

2
1. scibot 06 Jul 2026
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.immuni.2026.06.006
  
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2. scibot 05 Jul 2026
  
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  RRID: AB_439750
  
  DOI: 10.1016/j.immuni.2026.06.006
  
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sciencedirect.com/science/article/pii/S1074761326002578
May 2026
aacrjournals.org aacrjournals.org

VSIG4 restricts hepatocellular carcinoma control by suppressing tumor-specific CD8+ T cell immunity in the tumor microenvironment

1
1. scibot 05 May 2026
  
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  RRID:AB_439750
  
  DOI: 10.1158/2326-6066.CIR-25-0836
  
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aacrjournals.org/cancerimmunolres/article/14/5/718/784454/VSIG4-Restricts-Hepatocellular-Carcinoma-Control
Apr 2026
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Engineered oncolytic virus armed with anti-PCSK9 scFv boosts long-term CD8+ T cell immunity via rewiring MHC-I antigen presentation

1
1. scibot 02 Apr 2026
  
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  DOI: 10.1016/j.xcrm.2026.102724
  
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sciencedirect.com/science/article/pii/S2666379126001412
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer

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1. scibot 20 Dec 2025
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.xcrm.2025.102519
  
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sciencedirect.com:5037/science/article/pii/S2666379125005920
Oct 2025
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Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomes

1
1. scibot 04 Oct 2025
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.immuni.2025.09.004
  
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sciencedirect.com/science/article/pii/S1074761325004157
May 2025
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Foxp3 confers long-term efficacy of chimeric antigen receptor-T cells via metabolic reprogramming

1
1. scibot 17 May 2025
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.cmet.2025.04.008
  
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sciencedirect.com/science/article/pii/S1550413125002189
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Albumin-targeted oxaliplatin(iv) prodrugs bearing STING agonists

1
1. scibot 08 Apr 2025
  
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  RRID:AB_439750
  
  DOI: 10.1039/d5qi00433k
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11969438/
pubs.rsc.org pubs.rsc.org

Albumin-targeted oxaliplatin( iv ) prodrugs bearing STING agonists

1
1. scibot 07 Apr 2025
  
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  RRID:AB_439750
  
  DOI: 10.1039/D5QI00433K
  
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pubs.rsc.org/en/content/articlehtml/2025/qi/d5qi00433k
Mar 2025
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Dual role of HO-1 in mediating antiviral immune responses and mitigating excessive inflammatory damage during influenza virus infection

1
1. scibot 14 Mar 2025
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.isci.2025.112116
  
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sciencedirect.com/science/article/pii/S2589004225003761
Jan 2025
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Gut bacterial L-lysine alters metabolism and histone methylation to drive dendritic cell tolerance

1
1. scibot 03 Jan 2025
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.celrep.2024.115125
  
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sciencedirect.com/science/article/pii/S2211124724014761
Sep 2024
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mRNA-delivery of IDO1 suppresses T cell-mediated autoimmunity

1
1. scibot 10 Sep 2024
  
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  AB_439750
  
  DOI: 10.1016/j.xcrm.2024.101717
  
  Resource: (BioLegend Cat# 320014, RRID:AB_439750)
  
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sciencedirect.com/science/article/pii/S2666379124004385
Jun 2024
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Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement

1
1. scibot 06 Jun 2024
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.xcrm.2024.101590
  
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sciencedirect.com/science/article/pii/S2666379124002829
Aug 2023
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IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function

1
1. scibot 23 Aug 2023
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.celrep.2023.112996
  
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sciencedirect.com/science/article/pii/S2211124723010070
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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

1
1. scibot 12 Aug 2023
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.immuni.2023.07.014
  
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sciencedirect.com/science/article/pii/S1074761323003278
Apr 2023
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Intrauterine desensitization enables long term survival of human oligodendrocyte progenitor cells without immunosuppression

1
1. scibot 27 Apr 2023
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.isci.2023.106647
  
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sciencedirect.com/science/article/pii/S2589004223007241
Mar 2023
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Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity

1
1. scibot 02 Mar 2023
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.celrep.2023.112205
  
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sciencedirect.com/science/article/pii/S2211124723002164
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The altering cellular components and function in tumor microenvironment during remissive and relapsed stages of anti-CD19 CAR T-cell treated lymphoma mice

1
1. scibot 10 Feb 2023
  
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  AB_439750
  
  DOI: 10.3389/fimmu.2023.1101769
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9905118/
Dec 2022
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IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer

1
1. scibot 17 Dec 2022
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.ccell.2022.11.014
  
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sciencedirect.com/science/article/pii/S153561082200561X
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Maternal fiber deprivation alters microbiota in offspring, resulting in low-grade inflammation and predisposition to obesity

1
1. scibot 11 Dec 2022
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.chom.2022.10.014
  
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sciencedirect.com/science/article/pii/S1931312822005273
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Intratumoral Treatment with 5-Androstene-3β, 17α-Diol Reduces Tumor Size and Lung Metastasis in a Triple-Negative Experimental Model of Breast Cancer

1
1. scibot 26 Oct 2022
  
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  RRID:AB_439750
  
  DOI: 10.3390/ijms231911944
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9570136/
Aug 2022
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Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance

1
1. scibot 31 Aug 2022
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.celrep.2022.111308
  
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sciencedirect.com/science/article/pii/S2211124722011329
Jun 2022
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Optimal target saturation of ligand-blocking anti-GITR antibody IBI37G5 dictates FcγR-independent GITR agonism and antitumor activity

1
1. scibot 22 Jun 2022
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.xcrm.2022.100660
  
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sciencedirect.com/science/article/pii/S2666379122001926
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Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion

1
1. scibot 09 Jun 2022
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.immuni.2022.04.017
  
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sciencedirect.com/science/article/pii/S1074761322001881
Jul 2021
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Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity

1
1. scibot 31 Jul 2021
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.immuni.2018.12.011
  
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sciencedirect.com/science/article/pii/S1074761318305594
May 2021
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Dynamic changes to tissue-resident immunity after MHC-matched and MHC-mismatched solid organ transplantation

1
1. scibot 19 May 2021
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.celrep.2021.109141
  
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sciencedirect.com/science/article/pii/S2211124721004800
Apr 2021
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Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity

1
1. scibot 29 Apr 2021
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.cmet.2020.07.001
  
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sciencedirect.com/science/article/pii/S1550413120303594
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Double-Edged Sword: Interleukin-2 Promotes T Regulatory Cell Differentiation but Also Expands Interleukin-13- and Interferon-γ-Producing CD8+ T Cells via STAT6-GATA-3 Axis in Systemic Lupus Erythematosus

1
1. scibot 24 Mar 2021
  
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  AB_439750
  
  DOI: 10.3389/fimmu.2021.635531
  
  Resource: (BioLegend Cat# 320014, RRID:AB_439750)
  
  Curator: @evieth
  
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  RRIDCUR:Validated RRID:AB_439750
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ncbi.nlm.nih.gov/pmc/articles/PMC7982885/
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells

1
1. scibot 12 Feb 2021
  
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  RRID:AB_439750
  
  DOI: 10.7554/eLife.61841
  
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  RRID:AB_439750 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7872515/
Dec 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

1
1. scibot 10 Dec 2020
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.cell.2020.11.007
  
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  RRID:AB_439750 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7654323/
Sep 2020
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Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity

1
1. scibot 14 Sep 2020
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.cell.2020.02.015
  
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  RRID:AB_439750 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867420301598
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Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy

1
1. scibot 03 Sep 2020
  
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  RRID:AB_439750
  
  DOI: 10.1016/j.celrep.2019.12.013
  
  Resource: (BioLegend Cat# 320014, RRID:AB_439750)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_439750
  
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  RRID:AB_439750 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719316626
Nov 2018
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CTLA-4+PD-1− Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

1
1. scibot 05 Nov 2018
  
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  320014
  
  Curator: @Jmenke
  
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  (BioLegend Cat# 320014, RRID:AB_439750)
  
  SciCrunch record: RRID:AB_439750
  
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  RRID:AB_439750 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1074761317304296