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Hypoxia rescues complex 1-associated disease caused by proteostatic defects

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  DOI: 10.1038/s42255-026-01566-0
  
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nature.com/articles/s42255-026-01566-0
Jul 2026
dx.doi.org dx.doi.org

Dysregulation of glycogen metabolism in cardiomyopathy caused by glycogenin-1 (GYG1) missense variants

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1. scibot 01 Jul 2026
  
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  DOI: 10.1210/clinem/dgag212
  
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dx.doi.org/10.1210/clinem/dgag212
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

THC and CBD Induce Heme Oxygenase-1-Dependent Cell Death and Trigger Mitochondrial Dysfunction in Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells

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1. scibot 01 Apr 2026
  
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  DOI: 10.3390/antiox15030286
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13024539/
Mar 2026
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Oxidative phosphorylation patterns in pituitary adenoma/neuroendocrine tumors

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1. scibot 18 Mar 2026
  
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  DOI: 10.1007/s11102-026-01658-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12979347/
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THC and CBD Induce Heme Oxygenase-1-Dependent Cell Death and Trigger Mitochondrial Dysfunction in Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells

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  DOI: 10.3390/antiox15030286
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13024539/
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Mitochondrial VHL rewires cell metabolism in hypoxia

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  DOI: 10.1016/j.cmet.2025.11.013
  
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sciencedirect.com:5037/science/article/pii/S1550413125005273
Oct 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225021558-main-html.html

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1. scibot 30 Oct 2025
  
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  DOI: 10.1016/j.isci.2025.113894
  
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54.241.53.176/b4b988273c9e3e430c613d89df0807cdec71eb14/1-s2.0-S2589004225021558-main-html.html
Sep 2025
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Disruption of mitochondria-associated membranes contributes to the dysregulation of insulin secretion in undernutrition, obesity, and double burden of malnutrition

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.metabol.2025.156393
  
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sciencedirect.com/science/article/pii/S0026049525002628
Jun 2025
52.53.155.43 52.53.155.43

Bisecting GlcNAc modification of angiotensin-related glycoproteins in mouse kidney

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1. scibot 17 Jun 2025
  
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  DOI: 10.1093/jb/mvaf033
  
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52.53.155.43/1080ea79e7e6428758136ca91070a9ecb8246835/PDF-html.html
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Mitochondrial fumarate inhibits Parkin-mediated mitophagy

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1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.molcel.2025.05.021
  
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sciencedirect.com/science/article/pii/S1097276525004605
Mar 2025
www.nature.com www.nature.com

Induction of MASH-like pathogenesis in the Nwd1−/− mouse liver

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1. scibot 13 Mar 2025
  
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  DOI: 10.1038/s42003-025-07717-5
  
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nature.com/articles/s42003-025-07717-5
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Engineering mtDNA deletions by reconstituting end joining in human mitochondria

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.cell.2025.02.009
  
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sciencedirect.com/science/article/pii/S0092867425001941
Feb 2025
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Urolithin A provides cardioprotection and mitochondrial quality enhancement preclinically and improves human cardiovascular health biomarkers

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1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.111814
  
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sciencedirect.com/science/article/pii/S2589004225000744
Oct 2024
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Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division

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1. scibot 02 Oct 2024
  
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  DOI: 10.1016/j.celrep.2024.114794
  
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sciencedirect.com/science/article/pii/S2211124724011458
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Spastin regulates ER-mitochondrial contact sites and mitochondrial homeostasis

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1. scibot 12 Sep 2024
  
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  DOI: 10.1016/j.isci.2024.110683
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11382127/
Jul 2024
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Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus

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1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.xcrm.2024.101647
  
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sciencedirect.com/science/article/pii/S2666379124003616
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

KRAP regulates mitochondrial Ca2+ uptake by licensing IP3 receptor activity and stabilizing ER–mitochondrial junctions

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1. scibot 14 Jul 2024
  
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  DOI: 10.1242/jcs.261728
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11234384/
Jun 2024
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MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.cell.2024.05.017
  
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sciencedirect.com/science/article/pii/S0092867424005269
May 2024
www.biorxiv.org www.biorxiv.org

Induction of NASH in the Nwd1−/− mouse liver via SERCA2-dependent endoplasmic reticulum stress

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1. scibot 10 May 2024
  
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  DOI: 10.1101/2024.01.26.577307
  
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biorxiv.org/content/10.1101/2024.01.26.577307v2
52.53.155.43 52.53.155.43

Eicosapentaenoic acid increases proportion of type1 muscle fibers through PPARδ and AMPK pathways in rats

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1. scibot 10 May 2024
  
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  DOI: 10.1016/j.isci.2024.109816
  
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52.53.155.43/ef2eb540c316e37b8125f79aafdc12a777c8d945/PIIS2589004224010381-html.html
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4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease

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  DOI: 10.1016/j.celrep.2024.114148
  
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sciencedirect.com/science/article/pii/S2211124724004765
Apr 2024
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Multi-omic profiling reveals the endogenous and neoplastic responses to immunotherapies in cutaneous T cell lymphoma

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1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101527
  
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  DOI: 10.1016/j.xcrm.2024.101527
  
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sciencedirect.com/science/article/pii/S2666379124001964
Mar 2024
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A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders

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1. scibot 29 Mar 2024
  
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  DOI: 10.1016/j.bbadis.2024.167131
  
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sciencedirect.com/science/article/pii/S0925443924001200
Feb 2024
52.53.155.43 52.53.155.43

A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders

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  DOI: 10.1101/2023.10.24.563545
  
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52.53.155.43/208912a7429960b4182882fc2fcf60d73a185bc4/delete-html.html
actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com

Stimulating VAPB-PTPIP51 ER-mitochondria tethering corrects FTD/ALS mutant TDP43 linked Ca2+ and synaptic defects

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1. scibot 27 Feb 2024
  
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  DOI: 10.1186/s40478-024-01742-x
  
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actaneurocomms.biomedcentral.com/articles/10.1186/s40478-024-01742-x
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Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling

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1. scibot 04 Feb 2024
  
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  DOI: 10.1186/s12915-021-00979-5
  
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link.springer.com/article/10.1186/s12915-021-00979-5
Jan 2024
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HECW1 restrains cervical cancer cell growth by promoting DVL1 ubiquitination and downregulating the activation of Wnt/β-catenin signaling

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  DOI: 10.1016/j.yexcr.2024.113949
  
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sciencedirect.com/science/article/pii/S0014482724000399
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CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise

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  DOI: 10.1016/j.celrep.2023.113626
  
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sciencedirect.com/science/article/pii/S2211124723016376
Dec 2023
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MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle

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1. scibot 01 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113465
  
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sciencedirect.com/science/article/pii/S2211124723014778
Oct 2023
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 20 Oct 2023
  
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  DOI: 10.1111/bph.16174
  
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  RRID:AB_443084
  
  DOI: 10.1111/bph.16174
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16174
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α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity

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1. scibot 17 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113244
  
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sciencedirect.com/science/article/pii/S2211124723012561
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Mitochondrial DNA breaks activate an integrated stress response to reestablish homeostasis

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.molcel.2023.09.026
  
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sciencedirect.com/science/article/abs/pii/S1097276523007530
Aug 2023
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Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes

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1. scibot 27 Aug 2023
  
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  RRID:AB_443084
  
  DOI: 10.1016/j.cmet.2023.07.015
  
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Parkinson’s disease neurons exhibit alterations in mitochondrial quality control proteins

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Mitofusin-2 in nucleus accumbens D2-MSNs regulates social dominance and neuronal function

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Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons

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Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice

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Mitochondrial Bcl-xL promotes brain synaptogenesis by controlling non-lethal caspase activation

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Interaction between PI3K and the VDAC2 channel tethers Ras-PI3K-positive endosomes to mitochondria and promotes endosome maturation

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Bullatine A Has an Antidepressant Effect in Chronic Social Defeat Stress Mice; Implication of Microglial Inflammasome

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Hypoxic postconditioning restores mitophagy against transient global cerebral ischemia via Parkin-induced posttranslational modification of TBK1

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The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria

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Cyclophilin D-induced mitochondrial impairment confers... : Neural Regeneration Research

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Mechanisms and significance of tissue-specific MICU regulation of the mitochondrial calcium uniporter complex

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The human mitochondrial genome contains a second light strand promoter

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Role of Constitutive STAR in Mitochondrial Structure and Function in MA-10 Leydig Cells

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Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization

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DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease

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BPS Publications

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Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease

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Mosaic dysfunction of mitophagy in mitochondrial muscle disease

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PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes

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Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival

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An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens

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Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation

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Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

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  Mouse monoclonal Anti -VDAC
  
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<Emphasis Type="Italic">MSTO1</Emphasis> mutations cause mtDNA depletion, manifesting as muscular dystrophy with cerebellar involvement

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Biallelic Mutations in LIPT2 Cause a Mitochondrial Lipoylation Defect Associated with Severe Neonatal Encephalopathy

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Imaging mass cytometry reveals generalised deficiency in OXPHOS complexes in Parkinson’s disease

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Paradoxical Mitophagy Regulation by PINK1 and TUFm

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A Membrane-Bound Diacylglycerol Species Induces PKCϵ-Mediated Hepatic Insulin Resistance

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Comparative analysis of CI- and CIV-containing respiratory supercomplexes at single-cell resolution

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Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling

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Feb 2021
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Fatal Perinatal Mitochondrial Cardiac Failure Caused by Recurrent De Novo Duplications in the ATAD3 Locus

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Adenosine A2A receptor (A2AR) stimulation enhances mitochondrial metabolism and mitigates reactive oxygen species‐mediated mitochondrial injury

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Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly

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BPS Publications

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Oxygen-enhanced optoacoustic tomography reveals the effectiveness of targeting heme and oxidative phosphorylation at normalizing tumor vascular oxygenation

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Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer’s disease

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Dynamic Regulation of Mitochondrial Import by the Ubiquitin System

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Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits

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Genetic loss of AMPK-glycogen binding destabilizes AMPK and disrupts metabolism

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CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival

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MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition

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Differential effect of glucose on ER-mitochondria Ca2+ exchange participates to insulin secretion and to glucotoxicity-mediated dysfunction of β cells.

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PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin

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Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila

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UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses

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Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

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Miro1 Marks Parkinson’s Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson’s Models

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The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

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Mitochondrial Protein Synthesis and mtDNA Levels Coordinated through an Aminoacyl-tRNA Synthetase Subunit

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Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3‐dependent mechanism in male mice

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Untitled document

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Mitochondrial DNA Variation Dictates Expressivity and Progression of Nuclear DNA Mutations Causing Cardiomyopathy

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Mitohormesis in Mice via Sustained Basal Activation of Mitochondrial and Antioxidant Signaling

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Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles

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Systematic Functional Annotation of Somatic Mutations in Cancer

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TOM70 Sustains Cell Bioenergetics by Promoting IP3R3-Mediated ER to Mitochondria Ca2+ Transfer

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Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism

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α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton

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Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA

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Nov 2017
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Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages

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sciencedirect.com/science/article/pii/S0092867417309996
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Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses

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elifesciences.org/articles/24425
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Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions

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sciencedirect.com/science/article/pii/S0896627317302970
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IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact

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ncbi.nlm.nih.gov/pmc/articles/PMC5173324/
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Untitled document

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ncbi.nlm.nih.gov/pmc/articles/PMC5065686/
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MECR Mutations Cause Childhood-Onset Dystonia and Optic Atrophy, a Mitochondrial Fatty Acid Synthesis Disorder

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1. scibot 08 Nov 2017
  
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  Curator: @gabimpine
  
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Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number

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1. scibot 08 Nov 2017
  
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