157 Matching Annotations
  1. Apr 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
    1
    1. scibot 03 Apr 2024
      RRID:AB_443298

      DOI: 10.3390/ijms25063343

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    ncbi.nlm.nih.gov/pmc/articles/PMC10970352/
  3. Mar 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-random spatial organization of telomere varies during the cell cycle and requires LAP2 and BAF
    1
    1. scibot 22 Mar 2024
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      DOI: 10.1016/j.isci.2024.109343

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951912/
  5. www.sciencedirect.com www.sciencedirect.com
    The sirtuin-associated human senescence program converges on the activation of placenta-specific gene PAPPA
    2
    1. scibot 14 Mar 2024
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      DOI: 10.1016/j.devcel.2024.02.008

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    2. scibot 14 Mar 2024
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      DOI: 10.1016/j.devcel.2024.02.008

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    sciencedirect.com/science/article/pii/S1534580724001072
  6. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide
    1
    1. scibot 08 Mar 2024
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      DOI: 10.1016/j.molcel.2023.12.033

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    sciencedirect.com/science/article/pii/S1097276523010791
  7. www.sciencedirect.com www.sciencedirect.com
    AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway
    1
    1. scibot 08 Mar 2024
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      DOI: 10.1016/j.bbadis.2024.167116

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    sciencedirect.com/science/article/pii/S0925443924001054
  8. www.sciencedirect.com www.sciencedirect.com
    ApoE maintains neuronal integrity via miRNA and H3K27me3-mediated repression.
    2
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109231

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    2. scibot 06 Mar 2024
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      DOI: 10.1016/j.isci.2024.109231

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    sciencedirect.com/science/article/pii/S2589004224004528
  9. www.sciencedirect.com www.sciencedirect.com
    Cellular senescence is associated with the spatial evolution toward a higher metastatic phenotype in colorectal cancer
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113912

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    2. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113912

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    sciencedirect.com/science/article/pii/S2211124724002407
  10. Feb 2024
  11. www.jneurosci.org www.jneurosci.org
    Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice
    1
    1. scibot 16 Feb 2024
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      DOI: 10.1523/JNEUROSCI.1665-23.2023

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    jneurosci.org/content/44/7/e1665232023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cullin-RING E3 ubiquitin ligase 4 regulates neurite morphogenesis during neurodevelopment
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.isci.2024.108933

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    ncbi.nlm.nih.gov/pmc/articles/PMC10839267/
  13. Jan 2024
  14. 52.53.155.43 52.53.155.43
    JNEUROSCI.1665-23.2023.full-html.html
    2
    1. scibot 26 Jan 2024
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      DOI: 10.1523/jneurosci.1665-23.2023

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    2. scibot 23 Jan 2024
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      DOI: 10.1523/jneurosci.1665-23.2023

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    52.53.155.43/9add5f7e7c84e06696c302815bac67f6cb4d2d58/JNEUROSCI.1665-23.2023.full (1)-html.html
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres
    1
    1. scibot 14 Jan 2024
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      DOI: 10.1016/j.isci.2023.108655

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    ncbi.nlm.nih.gov/pmc/articles/PMC10783591/
  16. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.stem.2023.12.002

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    sciencedirect.com/science/article/pii/S1934590923004320
  17. link.springer.com link.springer.com
    Disparate macrophage responses are linked to infection outcome of Hantan virus in humans or rodents
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1038/s41467-024-44687-4

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    link.springer.com/article/10.1038/s41467-024-44687-4
  18. www.sciencedirect.com www.sciencedirect.com
    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
    1
    1. scibot 07 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113626

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    sciencedirect.com/science/article/pii/S2211124723016376
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1083/jcb.202304026

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    ncbi.nlm.nih.gov/pmc/articles/PMC10309186/
  20. Dec 2023
  21. www.sciencedirect.com www.sciencedirect.com
    A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
    1
    1. scibot 21 Dec 2023
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      DOI: 10.1016/j.isci.2023.108568

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    sciencedirect.com/science/article/pii/S2589004223026457
  22. www.sciencedirect.com www.sciencedirect.com
    TRPC4 deletion elicits behavioral defects in sociability by dysregulating expression of microRNA-138-2
    1
    1. scibot 21 Dec 2023
      RRID:AB_443298

      DOI: 10.1016/j.isci.2023.108617

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    sciencedirect.com/science/article/pii/S2589004223026949
  23. Nov 2023
  24. www.sciencedirect.com www.sciencedirect.com
    The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.molcel.2023.10.008

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    sciencedirect.com/science/article/pii/S1097276523008420
  25. www.sciencedirect.com www.sciencedirect.com
    Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.molcel.2023.10.017

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    sciencedirect.com/science/article/pii/S1097276523008547
  26. www.sciencedirect.com www.sciencedirect.com
    Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53
    1
    1. scibot 22 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113478

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    sciencedirect.com/science/article/pii/S2211124723014900
  27. www.biorxiv.org www.biorxiv.org
    Endonucleosis mediates internalization of cytoplasm into the nucleus in senescent cells
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1101/2023.11.12.566736

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    biorxiv.org/content/10.1101/2023.11.12.566736v1
  28. Oct 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.stem.2023.09.007

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    sciencedirect.com/science/article/pii/S1934590923003284
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep learning enables STORM-like superresolution image reconstruction from conventional microscopy
    1
    1. scibot 25 Oct 2023
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      DOI: 10.1016/j.isci.2023.108145

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    ncbi.nlm.nih.gov/pmc/articles/PMC10587619/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiangiogenic Action of JZL184 on Endothelial Cells via Inhibition of VEGF Expression in Hypoxic Lung Cancer Cells
    1
    1. scibot 18 Oct 2023
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      DOI: 10.3390/cells12192332

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    ncbi.nlm.nih.gov/pmc/articles/PMC10572003/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells
    1
    1. scibot 18 Oct 2023
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      DOI: 10.3390/cells12192389

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    ncbi.nlm.nih.gov/pmc/articles/PMC10571842/
  33. link.springer.com link.springer.com
    Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1186/s12967-023-04542-4

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    link.springer.com/article/10.1186/s12967-023-04542-4
  34. www.sciencedirect.com www.sciencedirect.com
    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.molcel.2023.09.023

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    sciencedirect.com/science/article/pii/S1097276523007505
  35. Sep 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Perturbations in 3D genome organization can promote acquired drug resistance
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113124

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    sciencedirect.com/science/article/pii/S2211124723011361
  37. www.sciencedirect.com www.sciencedirect.com
    Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.cell.2023.08.038

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    sciencedirect.com/science/article/pii/S0092867423009728
  38. Aug 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis
    1
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      DOI: 10.1016/j.cmet.2023.07.011

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    sciencedirect.com/science/article/pii/S155041312300270X
  40. www.sciencedirect.com www.sciencedirect.com
    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
    1
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      DOI: 10.1016/j.celrep.2023.112927

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    sciencedirect.com/science/article/pii/S2211124723009385
  41. Jul 2023
  42. www.sciencedirect.com www.sciencedirect.com
    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
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      DOI: 10.1016/j.celrep.2023.112848

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    sciencedirect.com/science/article/pii/S2211124723008598
  43. www.sciencedirect.com www.sciencedirect.com
    Generation of mouse hippocampal brain organoids from primary embryonic neural stem cells
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      DOI: 10.1016/j.xpro.2023.102413

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    sciencedirect.com/science/article/pii/S2666166723003805
  44. www.sciencedirect.com www.sciencedirect.com
    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
    1
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      DOI: 10.1016/j.ccell.2023.06.007

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    sciencedirect.com/science/article/pii/S1535610823002179
  45. Jun 2023
  46. www.nature.com www.nature.com
    Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice
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    1. scibot 22 Jun 2023
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      DOI: 10.1038/s41596-023-00831-w

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    nature.com/articles/s41596-023-00831-w
  47. www.sciencedirect.com www.sciencedirect.com
    Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation
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    1. scibot 03 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112578

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    sciencedirect.com/science/article/pii/S2211124723005892
  48. www.sciencedirect.com www.sciencedirect.com
    5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling
    1
    1. scibot 02 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112560

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    sciencedirect.com/science/article/pii/S2211124723005715
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    Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging
    1
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    Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
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    Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
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    Connections between sister and non-sister telomeres of segregating chromatids maintain euploidy
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    Cystatin B deficiency results in sustained histone H3 tail cleavage in postnatal mouse brain mediated by increased chromatin-associated cathepsin L activity
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    Processing and Subcellular Localization of the Hepatitis E Virus Replicase: Identification of Candidate Viral Factories
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    Localization of a TORC1-eIF4F translation complex during CD8+ T cell activation drives divergent cell fate
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    Processing and Subcellular Localization of the Hepatitis E Virus Replicase: Identification of Candidate Viral Factories
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    Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration
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    Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males
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  122. Jul 2021
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  130. May 2021
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    In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration
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  134. Apr 2021
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    Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan
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    Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration
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    Loss of Dystroglycan Drives Cellular Senescence via Defective Mitosis-Mediated Genomic Instability
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  160. Jan 2020
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    Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation
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      DOI: 10.1016/j.devcel.2019.05.032

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    HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70
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      DOI: 10.1016/j.celrep.2019.09.023

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    The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair
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      DOI: 10.1016/j.immuni.2019.06.005

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    Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors
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    Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
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    Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
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    Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks
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      DOI: 10.1016/j.celrep.2019.08.041

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    The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis
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      DOI: 10.1016/j.cub.2019.11.064

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  169. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Proteostasis network alteration in lysosomal storage disorders: Insights from the mouse model of Krabbe disease
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      DOI: 10.1002/jnr.24558

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    MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis
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      DOI: 10.1016/j.molcel.2018.09.031

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      DOI: 10.1016/j.celrep.2018.12.085

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      DOI: 10.1016/j.neuron.2019.01.048

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      DOI: 10.1016/j.devcel.2018.11.012

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  175. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1111/jnc.14538

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      DOI: 10.1016/j.devcel.2019.04.020

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      DOI: 10.1016/j.celrep.2019.01.105

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      DOI: 10.1016/j.stem.2018.12.002

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  179. Nov 2018
  180. www.sciencedirect.com www.sciencedirect.com
    Engaging pain fibers after a spinal cord injury fosters hemorrhage and expands the area of secondary injury
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    NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
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    Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness
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    Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown
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    Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer
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    Stress Granule Assembly Disrupts Nucleocytoplasmic Transport
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    A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response
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    HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types
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    Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport
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    Switch of Mitochondrial Superoxide Dismutase into a Prooxidant Peroxidase in Manganese-Deficient Cells and Mice
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    Mitophagy Controls the Activities of Tumor Suppressor p53 to Regulate Hepatic Cancer Stem Cells
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  191. Nov 2017
  192. elifesciences.org elifesciences.org
    Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology
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    The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines
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    Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation
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  195. elifesciences.org elifesciences.org
    KChIP2 is a core transcriptional regulator of cardiac excitability
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation
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