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Jun 2025
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Targeting CDK7/12/13 functional synergism reverses myofibroblast activation and ameliorates lung fibrosis

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sciencedirect.com/science/article/pii/S2589004225010399
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Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma

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  DOI: 10.7554/eLife.105339.1
  
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elifesciences.org/reviewed-preprints/105339v1
May 2025
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Stm1 regulates Ifh1 activity revealing crosstalk between ribosome biogenesis and ribosome dormancy

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  DOI: 10.1016/j.molcel.2025.04.008
  
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sciencedirect.com/science/article/pii/S1097276525003119
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KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy

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  DOI: 10.1016/j.ccell.2025.04.002
  
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sciencedirect.com/science/article/pii/S1535610825001394
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma

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  DOI: 10.1126/sciadv.adq2519
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11980859/
Jan 2025
52.53.155.43 52.53.155.43

jkaf012-html.html

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  DOI: 10.1093/g3journal/jkaf012
  
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52.53.155.43/ad66d1769782719c2c3cb2ffd8f6b0a226401c33/jkaf012-html.html
Nov 2023
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Targeted perturbation of signaling-driven condensates

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Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition

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sciencedirect.com/science/article/pii/S1097276523008547
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A Proximal Sox2 Enhancer Cluster is Required for the Anterior Regional Identity of Neural Progenitors

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  DOI: 10.1101/2023.11.09.566464
  
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biorxiv.org/content/10.1101/2023.11.09.566464v1
Apr 2023
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Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting

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PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection

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  DOI: 10.1016/j.celrep.2023.112341
  
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sciencedirect.com/science/article/pii/S2211124723003522
Mar 2023
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Chromatin profiling identifies transcriptional readthrough as a conserved mechanism for piRNA biogenesis in mosquitoes

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  DOI: 10.1016/j.celrep.2023.112257
  
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europepmc.org/article/med/36930642
Jan 2023
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EKLF/Klf1 regulates erythroid transcription by its pioneering activity and selective control of RNA Pol II pause-release

1
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  DOI: 10.1016/j.celrep.2022.111830
  
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sciencedirect.com/science/article/pii/S2211124722017223
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MDC1 maintains active elongation complexes of RNA polymerase II

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1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111979
  
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Distinct patterns of RNA polymerase II and transcriptional elongation characterize mammalian genome activation

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  DOI: 10.1016/j.celrep.2022.111865
  
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sciencedirect.com/science/article/pii/S2211124722017612
Nov 2022
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Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci

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1. scibot 03 Nov 2022
  
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  DOI: 10.1016/j.molcel.2022.10.004
  
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sciencedirect.com/science/article/pii/S1097276522009613
Oct 2022
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p300/CBP sustains Polycomb silencing by non-enzymatic functions

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sciencedirect.com/science/article/pii/S1097276522008942
Sep 2022
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SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA

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1. scibot 24 Sep 2022
  
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  DOI: 10.1016/j.molcel.2022.08.031
  
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sciencedirect.com/science/article/pii/S1097276522008516
Mar 2022
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The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes

1
1. scibot 16 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110524
  
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MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape

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  DOI: 10.1016/j.molcel.2022.02.013
  
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sciencedirect.com/science/article/pii/S1097276522001186
Nov 2021
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A role for SMARCB1 in synovial sarcomagenesis reveals that SS18-SSX induces canonical BAF destruction

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1. scibot 09 Nov 2021
  
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  DOI: 10.1158/2159-8290.CD-20-1219
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8567602/
Aug 2021
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A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory

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  DOI: 10.7554/eLife.22467
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5293492/
Jul 2021
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Tracing MYC Expression for Small Molecule Discovery

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  DOI: 10.1016/j.chembiol.2019.02.007
  
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sciencedirect.com/science/article/pii/S245194561930042X
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A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory

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  DOI: 10.7554/eLife.22467
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5293492/
Jun 2021
elifesciences.org elifesciences.org

Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis

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  DOI: 10.7554/eLife.58342
  
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elifesciences.org/articles/58342
May 2021
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Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release

1
1. scibot 08 May 2021
  
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  DOI: 10.1016/j.molcel.2021.03.008
  
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sciencedirect.com/science/article/pii/S1097276521001763
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Dek Modulates Global Intron Retention during Muscle Stem Cells Quiescence Exit

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  DOI: 10.1016/j.devcel.2020.05.006
  
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The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability

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sciencedirect.com/science/article/pii/S1097276521003142
Apr 2021
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Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action

1
1. scibot 29 Apr 2021
  
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  DOI: 10.1016/j.cmet.2020.07.002
  
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sciencedirect.com/science/article/pii/S1550413120303600
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers

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  DOI: 10.1016/j.celrep.2020.107929
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7383238/
Sep 2020
academic.oup.com academic.oup.com

The Transcription Factor NR4A2 Plays an Essential Role in Driving Prolactin Expression in Female Pituitary Lactotropes

1
1. scibot 26 Sep 2020
  
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  DOI: 10.1210/endocr/bqaa046
  
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academic.oup.com/endo/article/161/5/bqaa046/5809733
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Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication

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  DOI: 10.1038/s41467-020-14299-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6972770/
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The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts

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  DOI: 10.1016/j.celrep.2020.107917
  
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sciencedirect.com/science/article/pii/S2211124720308986
Jan 2020
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Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization

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  DOI: 10.1016/j.ccell.2019.08.006
  
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sciencedirect.com/science/article/pii/S1535610819303745
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Stress-Induced Epigenetic Changes in Hippocampal Mkp-1 Promote Persistent Depressive Behaviors

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1. scibot 13 Jan 2020
  
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  DOI: 10.1007/s12035-019-01689-4
  
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link.springer.com/article/10.1007/s12035-019-01689-4
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Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.devcel.2019.05.037
  
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Regulation of SETD7 Methyltransferase by SENP3 Is Crucial for Sarcomere Organization and Cachexia

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Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting

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Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element

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A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response

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The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages

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CBP Regulates Recruitment and Release of Promoter-Proximal RNA Polymerase II

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Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots

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