53 Matching Annotations
  1. Jun 2025
  2. www.sciencedirect.com www.sciencedirect.com
    A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis
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    sciencedirect.com/science/article/pii/S1535610825002569
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    Genetic signatures in the highly virulent subtype B human immunodeficiency virus-1 conferring resistance to broadly neutralizing antibodies
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  4. Apr 2025
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    Microbiota-derived bile acids antagonize the host androgen receptor and drive anti-tumor immunity
    1
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  6. Mar 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The costimulatory domain influences CD19 CAR-T cell resistance development in B-cell malignancies
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    The NF1 tumor suppressor regulates PD-L1 and immune evasion in melanoma
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    sciencedirect.com/science/article/pii/S2211124725001366
  9. Feb 2025
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    Acidic pH can attenuate immune killing through inactivation of perforin
    1
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    Glycolytic reprogramming shapes the histone acetylation profile of activated CD4+ T cells in juvenile idiopathic arthritis
    1
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  12. Jan 2025
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    Amniotic epithelial Cell microvesicles uptake inhibits PBMCs and Jurkat cells activation by inducing mitochondria-dependent apoptosis
    1
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    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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    sciencedirect.com/science/article/pii/S1074761324005685
  15. Dec 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Leveraging Vγ9Vδ2 T cells against prostate cancer through a VHH-based PSMA-Vδ2 bispecific T cell engager
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  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer
    1
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  18. 52.53.155.43 52.53.155.43
    1-s2.0-S2472630324001146-main-html.html
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    Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma
    1
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    sciencedirect.com/science/article/pii/S2211124724013664
  20. Oct 2024
  21. link.springer.com link.springer.com
    Antitumor effects of intracranial injection of B7-H3-targeted Car-T and Car-Nk cells in a patient-derived glioblastoma xenograft model
    1
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      DOI: 10.1007/s00262-024-03808-0

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  22. Sep 2024
  23. www.sciencedirect.com www.sciencedirect.com
    The rebalancing of the immune system at the maternal-fetal interface ameliorates autism-like behavior in adult offspring
    1
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  24. Aug 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Statins inhibit paclitaxel-induced PD-L1 expression and increase CD8+ T cytotoxicity for better prognosis in breast cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11325938/
  26. www.cell.com www.cell.com
    KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations in humans
    1
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      DOI: 10.1016/j.celrep.2023.112236

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    cell.com/cell-reports/fulltext/S2211-1247(23)00247-4
  27. Jul 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Amphiregulin orchestrates the paracrine immune-suppressive function of amniotic-derived cells through its interplay with COX-2/PGE2/EP4 axis
    1
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    sciencedirect.com/science/article/pii/S2589004224017334
  29. May 2024
  30. aacrjournals.org aacrjournals.org
    Breast Cancer Stem Cells Secrete MIF to Mediate Tumor Metabolic Reprogramming that Drives Immune Evasion
    1
    1. scibot 23 May 2024
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      DOI: 10.1158/0008-5472.CAN-23-2390

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    aacrjournals.org/cancerres/article/84/8/1270/742984/Breast-Cancer-Stem-Cells-Secrete-MIF-to-Mediate
  31. Apr 2024
  32. www.sciencedirect.com www.sciencedirect.com
    ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
    1
    1. scibot 16 Apr 2024
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  33. Mar 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immuno-oncological effects of standard anticancer agents and commonly used concomitant drugs: an in vitro assessment
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    ncbi.nlm.nih.gov/pmc/articles/PMC10913607/
  35. www.sciencedirect.com www.sciencedirect.com
    Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8+ T cells
    2
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      DOI: 10.1016/j.celrep.2024.113853

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    sciencedirect.com/science/article/pii/S2211124724001815
  36. Feb 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment
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    sciencedirect.com/science/article/pii/S2211124724001256
  38. Jun 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation
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    1. scibot 03 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112583

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  40. Mar 2023
  41. www.cell.com www.cell.com
    KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations in humans
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      DOI: 10.1016/j.celrep.2023.112236

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    cell.com/cell-reports/fulltext/S2211-1247(23)00247-4
  42. www.sciencedirect.com www.sciencedirect.com
    Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity
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      DOI: 10.1016/j.cmet.2023.02.013

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  43. Feb 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death
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      DOI: 10.1186/s12885-023-10645-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC9938546/
  45. Jan 2023
  46. aacrjournals.org aacrjournals.org
    Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
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      DOI: 10.1158/2159-8290.CD-21-1463

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    aacrjournals.org/cancerdiscovery/article/12/8/1942/707227/Enhancing-PD-L1-Degradation-by-ITCH-during-MAPK
  47. Sep 2022
  48. www.sciencedirect.com www.sciencedirect.com
    Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
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  49. Jun 2022
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    Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity
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      DOI: 10.1016/j.immuni.2022.05.012

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  51. Apr 2022
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    A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers
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  53. Feb 2022
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    Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments
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    sciencedirect.com/science/article/pii/S1535610822000034
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    PD-1 blockade therapy promotes infiltration of tumor-attacking exhausted T cell clonotypes
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    sciencedirect.com/science/article/pii/S221112472200047X
  56. Dec 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Coenzyme A fuels T cell anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1550413121005386
  58. Sep 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming
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      16-0037-81

      DOI: 10.1016/j.cmet.2021.09.002

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  60. Aug 2021
  61. www.cell.com www.cell.com
    Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma
    1
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      DOI: 10.1016/j.cell.2018.11.043

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    cell.com/cell/fulltext/S0092-8674(18)31568-X
  62. Jul 2021
  63. elifesciences.org elifesciences.org
    Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members
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      DOI: 10.7554/eLife.44360

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    elifesciences.org/articles/44360
  64. www.sciencedirect.com www.sciencedirect.com
    Morphological profiling of human T and NK lymphocytes by high-content cell imaging
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      DOI: 10.1016/j.celrep.2021.109318

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  65. May 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
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    1. scibot 06 May 2021
      RRID:AB_468854

      DOI: 10.1016/j.immuni.2020.09.006

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  67. www.sciencedirect.com www.sciencedirect.com
    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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    1. scibot 06 May 2021
      RRID:AB_468854

      DOI: 10.1016/j.immuni.2020.06.016

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    sciencedirect.com/science/article/pii/S1074761320302715
  68. Feb 2021
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells
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      RRID:AB_468854

      DOI: 10.7554/eLife.61841

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    ncbi.nlm.nih.gov/pmc/articles/PMC7872515/
  70. Nov 2020
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unbiased Screens Show CD8+ T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein
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    1. scibot 04 Nov 2020
      RRID:AB_468854

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  72. Oct 2020
  73. www.sciencedirect.com www.sciencedirect.com
    IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression
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    1. scibot 31 Oct 2020
      RRID:AB_468854

      DOI: 10.1016/j.cell.2020.07.038

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    sciencedirect.com/science/article/pii/S0092867420309466
  74. Sep 2020
  75. www.sciencedirect.com www.sciencedirect.com
    Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis
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      RRID:AB_468854

      DOI: 10.1016/j.celrep.2020.02.062

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  76. www.nature.com www.nature.com
    Engineering primary T cells with chimeric antigen receptors for rewired responses to soluble ligands
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      RRID:AB_468854

      DOI: 10.1038/s41596-020-0294-8

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  77. Jan 2020
  78. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.chembiol.2018.11.011

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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.7554/eLife.44360

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  80. Nov 2018
  81. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S221112471831533X
  82. www.sciencedirect.com www.sciencedirect.com
    Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
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    sciencedirect.com/science/article/pii/S1097276518305999
  83. www.sciencedirect.com www.sciencedirect.com
    Innate-like Cytotoxic Function of Bystander-Activated CD8+ T Cells Is Associated with Liver Injury in Acute Hepatitis A
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    sciencedirect.com/science/article/pii/S1074761317305265
  84. Nov 2017
  85. www.sciencedirect.com www.sciencedirect.com
    Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease
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    1. scibot 08 Nov 2017
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      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S1934590917300322
  86. www.sciencedirect.com www.sciencedirect.com
    Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity
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      Curator: @chewbeccax

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