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Engineering oral commensal nanovaccines to activate mucosal-systemic immune cascades against tumor

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1. scibot 26 Jul 2026
  
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  DOI: 10.1016/j.chom.2026.06.021
  
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sciencedirect.com/science/article/pii/S1931312826002817
Jul 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting the αvβ5 Integrin Modifies the TGF-β-Rich Tumor Microenvironment of Pancreatic Cancer

1
1. scibot 15 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-4223
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13353084/
Apr 2026
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An SPP1-SOCS1 pathway constrains interferon responses in tumor-associated macrophages and shapes an immunosuppressive tumor microenvironment

1
1. scibot 29 Apr 2026
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.immuni.2026.04.001
  
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sciencedirect.com/science/article/pii/S107476132600141X
Mar 2026
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 19 Mar 2026
  
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  RRID:AB_468921
  
  DOI: 10.1111/bph.70383
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70383
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In vivo CAR-Tfh cell reprogramming restores tolerance in a mouse model of autoimmune hepatitis

1
1. scibot 17 Mar 2026
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.stem.2026.02.006
  
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sciencedirect.com/science/article/pii/S1934590926000767
Feb 2026
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Functional nutrient-genetic profiling reveals biotin and FBXW7 are essential to bypass glutamine addiction

1
1. scibot 26 Feb 2026
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.molcel.2026.02.002
  
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sciencedirect.com/science/article/pii/S1097276526000973
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Preoperative exercise induces anti-tumor Kupffer cells to prevent surgical stress-promoted colorectal cancer liver metastasis

1
1. scibot 10 Feb 2026
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.xcrm.2026.102589
  
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sciencedirect.com/science/article/pii/S2666379126000066
Jan 2026
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Cannabidiol suppresses emergency MDSCs generation by disturbing EEF1B2-mediated C/EBPβ protein synthesis in colorectal adenomas

1
1. scibot 16 Jan 2026
  
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  RRID:AB_468921
  
  DOI: 10.1136/jitc-2025-013081
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12766802/
Dec 2025
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Glycolysis maintains effector function of lung Th17 TRM cells in precision cut lung slices

1
1. scibot 19 Dec 2025
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.isci.2025.114051
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12702243/
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Gut microbiota promotes immune tolerance at the maternal-fetal interface

1
1. scibot 18 Dec 2025
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.cell.2025.11.022
  
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sciencedirect.com:5037/science/article/pii/S0092867425013182
Nov 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225023120-main-html.html

1
1. scibot 15 Nov 2025
  
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  AB_468921
  
  DOI: 10.1016/j.isci.2025.114051
  
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54.241.53.176/1938cfb41871d36b856cc7869ae28b52c007495e/1-s2.0-S2589004225023120-main-html.html
Aug 2025
www.cell.com www.cell.com

DNASE1L3-expressing dendritic cells promote CD8+ T cell function and anti-PD-(L)1 therapy efficacy by degrading neutrophil extracellular traps

1
1. scibot 15 Aug 2025
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.ccell.2025.07.014
  
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cell.com/cancer-cell/abstract/S1535-6108(25)00320-4
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism

1
1. scibot 30 Jul 2025
  
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  RRID:AB_468921
  
  DOI: 10.7554/eLife.104423
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12303568/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting Intracellular Innate RNA-Sensing Systems Overcomes Resistance to CAR T-cell Therapy in Solid Tumors

1
1. scibot 17 Jul 2025
  
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  AB_468921
  
  DOI: 10.1158/0008-5472.CAN-24-3425
  
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  Curator: @sonofthor
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12260516/
May 2025
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Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment

1
1. scibot 29 May 2025
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.immuni.2025.04.030
  
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sciencedirect.com/science/article/pii/S1074761325001931
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PIM kinase control of CD8 T cell protein synthesis and cell trafficking

1
1. scibot 22 May 2025
  
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  RRID:AB_468921
  
  DOI: 10.7554/eLife.98622
  
  Resource: (Thermo Fisher Scientific Cat# 16-0281-82, RRID:AB_468921)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12074636/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms

1
1. scibot 22 May 2025
  
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  RRID:AB_468921
  
  DOI: 10.7554/eLife.96868
  
  Resource: (Thermo Fisher Scientific Cat# 16-0281-82, RRID:AB_468921)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12077877/
Apr 2025
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Microbiota-derived bile acids antagonize the host androgen receptor and drive anti-tumor immunity

1
1. scibot 17 Apr 2025
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.cell.2025.02.029
  
  Resource: (Thermo Fisher Scientific Cat# 16-0281-82, RRID:AB_468921)
  
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sciencedirect.com/science/article/pii/S0092867425002569
Mar 2025
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Anti-vascular endothelial growth factor treatment potentiates immune checkpoint blockade through a BAFF- and IL-12-dependent reprogramming of the TME

1
1. scibot 20 Mar 2025
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.immuni.2025.02.017
  
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sciencedirect.com/science/article/pii/S1074761325000846
Feb 2025
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A secondary metabolite of Limosilactobacillus reuteri R2lc drives strain-specific pathology in a spontaneous mouse model of multiple sclerosis

1
1. scibot 25 Feb 2025
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.celrep.2025.115321
  
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sciencedirect.com/science/article/pii/S2211124725000920
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Activation of IL-2/IL-2R pathway by Hedyotis diffusa polysaccharide improves immunotherapy in colorectal cancer

1
1. scibot 20 Feb 2025
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.ijbiomac.2025.141013
  
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sciencedirect.com/science/article/pii/S0141813025015624
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Glycolytic reprogramming shapes the histone acetylation profile of activated CD4+ T cells in juvenile idiopathic arthritis

1
1. scibot 20 Feb 2025
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.celrep.2025.115287
  
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sciencedirect.com/science/article/pii/S2211124725000580
Dec 2024
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Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia

1
1. scibot 10 Dec 2024
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.celrep.2024.115056
  
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sciencedirect.com/science/article/pii/S2211124724014074
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Statins inhibit paclitaxel-induced PD-L1 expression and increase CD8+ T cytotoxicity for better prognosis in breast cancer

1
1. scibot 21 Aug 2024
  
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  RRID:AB_46892
  
  DOI: 10.1097/JS9.0000000000001582
  
  Resource: (Thermo Fisher Scientific Cat# 16-0281-82, RRID:AB_468921)
  
  Curator: @evieth
  
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  RRIDCUR:Unresolved RRID:AB_468921
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ncbi.nlm.nih.gov/pmc/articles/PMC11325938/
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Tumor-derived exosomal ICAM1 promotes bone metastasis of triple-negative breast cancer by inducing CD8+ T cell exhaustion

1
1. scibot 14 Aug 2024
  
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  16-0281-82
  
  DOI: 10.1016/j.biocel.2024.106637
  
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  Curator: @vtello
  
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sciencedirect.com/science/article/pii/S1357272524001298
May 2024
52.53.155.43 52.53.155.43

Ablation of Atp5if1 impairs metabolic reprogramming and proliferation of T lymphocytes and compromises mouse survival

1
1. scibot 09 May 2024
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.isci.2024.109863
  
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52.53.155.43/78682a2f6a3221e55b1ab1536c5aacb68d35b4d1/PIIS258900422401085X-html.html
Apr 2024
www.sciencedirect.com www.sciencedirect.com

CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment

1
1. scibot 30 Apr 2024
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.immuni.2024.04.003
  
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sciencedirect.com/science/article/pii/S1074761324002085
www.embopress.org www.embopress.org

The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor

1
1. scibot 25 Apr 2024
  
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  Thermo Scientific, 16-0281-82
  
  DOI: 10.1038/s44321-024-00051-z
  
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  Curator: @abever99
  
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embopress.org/doi/full/10.1038/s44321-024-00051-z
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ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion

1
1. scibot 16 Apr 2024
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.cell.2024.03.019
  
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sciencedirect.com/science/article/pii/S0092867424003106
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting abatacept-resistant T-helper-17 cells by aldehyde dehydrogenase inhibition

1
1. scibot 18 Jan 2024
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.isci.2023.108646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10788227/
Dec 2023
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Oral tolerance to systemic vaccination remains intact without RORγt expression in regulatory T cells

1
1. scibot 21 Dec 2023
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.isci.2023.108504
  
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sciencedirect.com/science/article/pii/S2589004223025816
Oct 2023
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Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury

1
1. scibot 14 Oct 2023
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.isci.2023.107947
  
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  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2589004223020242
Jul 2023
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LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer

1
1. scibot 13 Jul 2023
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.devcel.2023.06.006
  
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  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1534580723003040
Jun 2023
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Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation

1
1. scibot 03 Jun 2023
  
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  RRID:AB_468921
  
  DOI: 10.1016/j.celrep.2023.112583
  
  Resource: (Thermo Fisher Scientific Cat# 16-0281-82, RRID:AB_468921)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124723005946
Apr 2023
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The importance of the timing of microbial signals for perinatal immune system development

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  DOI: 10.20517/mrr.2023.03
  
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DNA architectural protein CTCF facilitates subset-specific chromatin interactions to limit the formation of memory CD8+ T cells

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Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance

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Bone marrow hematopoiesis drives multiple sclerosis progression

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Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity

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Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

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  DOI: 10.1016/j.molcel.2022.02.033
  
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Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses

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  DOI: 10.12688/wellcomeopenres.16834.1
  
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Jan 2022
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A purine metabolic checkpoint that prevents autoimmunity and autoinflammation

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  DOI: 10.1016/j.cmet.2021.12.009
  
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Macrophages are metabolically heterogeneous within the tumor microenvironment

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Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity

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Coenzyme A fuels T cell anti-tumor immunity

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Aug 2021
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Untitled document

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  DOI: 10.7554/eLife.44210
  
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Jul 2021
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Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation

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May 2021
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Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells

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  DOI: 10.1016/j.celrep.2021.109120
  
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Apr 2021
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In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

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  DOI: 10.1016/j.cell.2021.02.019
  
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Mar 2021
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Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging

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Feb 2021
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Integration of IL-2 and IL-4 signals coordinates divergent regulatory T cell responses and drives therapeutic efficacy

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  DOI: 10.7554/eLife.57417
  
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Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

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  DOI: 10.7554/eLife.53725
  
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PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

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  Anti-CD28 (37.51)
  
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Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency

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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

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Concomitant Infection of S. mansoni and H. pylori Promotes Promiscuity of Antigen-Experienced Cells and Primes the Liver for a Lower Fibrotic Response

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Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis

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Untitled document

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Untitled document

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  DOI: 10.1016/j.cell.2019.03.025
  
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Nov 2017
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The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression

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