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Genome-Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

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1. scibot 28 May 2026
  
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  DOI: 10.1002/advs.202515158
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515158
May 2026
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Expansion of NKG2A+CD8+ T cells with regulatory signatures distinguish individuals living with HIV-2 from those with HIV-1

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1. scibot 16 May 2026
  
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  DOI: 10.1016/j.medj.2026.101143
  
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sciencedirect.com/science/article/pii/S2666634026001467
Apr 2026
54.241.53.176 54.241.53.176

cd-25-1907-html.html

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/2159-8290.CD-25-1907
  
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54.241.53.176/c343cff9cf99b6aff211bdef582679d3b0f1da71/cd-25-1907-html.html
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Immunological effects of amivantamab in EGFR or MET-expressing non-small cell lung cancer

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1. scibot 27 Mar 2026
  
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  DOI: 10.1007/s00262-026-04369-0
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13013883/
Sep 2025
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Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens

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1. scibot 27 Sep 2025
  
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  DOI: 10.1016/j.cell.2025.09.001
  
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sciencedirect.com/science/article/pii/S0092867425010323
Aug 2025
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Lymphoma accelerates T cell and tissue aging

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.023
  
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sciencedirect.com/science/article/pii/S1535610825003290
Jul 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225014956-main-html.html

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1. scibot 31 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113234
  
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52.53.155.43/db4dc1752e05cc3cf4232a74539639afb8948991/1-s2.0-S2589004225014956-main-html.html
Jun 2025
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A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.ccell.2025.06.006
  
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sciencedirect.com/science/article/pii/S1535610825002569
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Genetic signatures in the highly virulent subtype B human immunodeficiency virus-1 conferring resistance to broadly neutralizing antibodies

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112847
  
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sciencedirect.com/science/article/pii/S2589004225011083
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Step-Wise Assembly of LAT Signaling Clusters Immediately After T Cell Receptor Triggering Contributes to Signal Propagation

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1. scibot 21 May 2025
  
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  DOI: 10.3390/ijms26094076
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12071625/
Apr 2025
aacrjournals.org aacrjournals.org

SEMA3G-NRP1 Signaling Functions as an Immune Checkpoint that Enables Tumor Immune Evasion by Impairing T Cell Cytotoxicity

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1. scibot 17 Apr 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2223
  
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aacrjournals.org/cancerres/article/85/5/912/751997/SEMA3G-NRP1-Signaling-Functions-as-an-Immune
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The costimulatory domain influences CD19 CAR-T cell resistance development in B-cell malignancies

1
1. scibot 23 Mar 2025
  
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  DOI: 10.1101/2025.02.28.640707
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11908201/
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Immediate early splicing controls translation in activated T-cells and is mediated by hnRNPC2 phosphorylation

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1. scibot 23 Mar 2025
  
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  DOI: 10.1038/s44318-025-00374-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11914300/
Feb 2025
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Glycolytic reprogramming shapes the histone acetylation profile of activated CD4+ T cells in juvenile idiopathic arthritis

1
1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115287
  
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sciencedirect.com/science/article/pii/S2211124725000580
52.53.155.43 52.53.155.43

can-24-2223-html.html

1
1. scibot 13 Feb 2025
  
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  RRID:AB_468926
  
  DOI: 10.1158/0008-5472.can-24-2223
  
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52.53.155.43/752d85b7b45cbe249ff1ba5f1b04c7c2ca434b68/can-24-2223-html.html
Jan 2025
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Amniotic epithelial Cell microvesicles uptake inhibits PBMCs and Jurkat cells activation by inducing mitochondria-dependent apoptosis

1
1. scibot 31 Jan 2025
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.isci.2025.111830
  
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sciencedirect.com/science/article/pii/S2589004225000902
Oct 2024
link.springer.com link.springer.com

Antitumor effects of intracranial injection of B7-H3-targeted Car-T and Car-Nk cells in a patient-derived glioblastoma xenograft model

1
1. scibot 08 Oct 2024
  
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  RRID:AB_468926
  
  DOI: 10.1007/s00262-024-03808-0
  
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link.springer.com/article/10.1007/s00262-024-03808-0
Sep 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Induction of immortal-like and functional CAR T cells by defined factors

1
1. scibot 27 Sep 2024
  
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  RRID:AB_468926
  
  DOI: 10.1084/jem.20232368
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10965394/
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The rebalancing of the immune system at the maternal-fetal interface ameliorates autism-like behavior in adult offspring

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114787
  
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sciencedirect.com/science/article/pii/S2211124724011380
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Statins inhibit paclitaxel-induced PD-L1 expression and increase CD8+ T cytotoxicity for better prognosis in breast cancer

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1. scibot 22 Aug 2024
  
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  RRID:AB_468926
  
  DOI: 10.1097/JS9.0000000000001582
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11325938/
Jul 2024
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Amphiregulin orchestrates the paracrine immune-suppressive function of amniotic-derived cells through its interplay with COX-2/PGE2/EP4 axis

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1. scibot 26 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110508
  
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sciencedirect.com/science/article/pii/S2589004224017334
May 2024
aacrjournals.org aacrjournals.org

Breast Cancer Stem Cells Secrete MIF to Mediate Tumor Metabolic Reprogramming that Drives Immune Evasion

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1. scibot 23 May 2024
  
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  RRID: AB468926
  
  DOI: 10.1158/0008-5472.CAN-23-2390
  
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aacrjournals.org/cancerres/article/84/8/1270/742984/Breast-Cancer-Stem-Cells-Secrete-MIF-to-Mediate
Feb 2024
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Single-cell analysis reveals insights into epithelial abnormalities in ovarian endometriosis

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1. scibot 29 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113716
  
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sciencedirect.com/science/article/pii/S2211124724000445
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Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113797
  
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sciencedirect.com/science/article/pii/S2211124724001256
Jan 2024
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Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.xcrm.2023.101374
  
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sciencedirect.com/science/article/pii/S2666379123006031
Nov 2023
www.biorxiv.org www.biorxiv.org

Induction of immortal-like and functional CAR-T cells by defined factors

1
1. scibot 17 Nov 2023
  
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  RRID:AB_468926
  
  DOI: 10.1101/2023.11.06.565785
  
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biorxiv.org/content/10.1101/2023.11.06.565785v1
Aug 2023
www.nature.com www.nature.com

TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation

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1. scibot 24 Aug 2023
  
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  RRID:AB_468926
  
  DOI: 10.1038/s41467-023-40755-3
  
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nature.com/articles/s41467-023-40755-3
Jun 2023
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Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation

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1. scibot 03 Jun 2023
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.celrep.2023.112583
  
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sciencedirect.com/science/article/pii/S2211124723005946
Apr 2023
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Phenotypic plasticity and reduced tissue retention of exhausted tumor-infiltrating T cells following neoadjuvant immunotherapy in head and neck cancer

1
1. scibot 14 Apr 2023
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.ccell.2023.03.014
  
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sciencedirect.com/science/article/pii/S1535610823000879
www.nature.com www.nature.com

Membrane phase separation drives responsive assembly of receptor signaling domains

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1. scibot 05 Apr 2023
  
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  RRID:AB_468926
  
  DOI: 10.1038/s41589-023-01268-8
  
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nature.com/articles/s41589-023-01268-8
Jan 2023
aacrjournals.org aacrjournals.org

Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance

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1. scibot 11 Jan 2023
  
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  DOI: 10.1158/2159-8290.CD-21-1463
  
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aacrjournals.org/cancerdiscovery/article/12/8/1942/707227/Enhancing-PD-L1-Degradation-by-ITCH-during-MAPK
Nov 2022
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Systematic single-cell pathway analysis to characterize early T cell activation

1
1. scibot 23 Nov 2022
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.celrep.2022.111697
  
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sciencedirect.com/science/article/pii/S2211124722015716
Sep 2022
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Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses

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1. scibot 30 Sep 2022
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.ccell.2022.09.007
  
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sciencedirect.com/science/article/pii/S1535610822004366
Jun 2022
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Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity

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1. scibot 15 Jun 2022
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.immuni.2022.05.012
  
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sciencedirect.com/science/article/pii/S1074761322002321
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Human CD4+CD25+CD226- Tregs Demonstrate Increased Purity, Lineage Stability, and Suppressive Capacity Versus CD4+CD25+CD127lo/- Tregs for Adoptive Cell Therapy

1
1. scibot 11 Jun 2022
  
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  RRID:AB_468926
  
  DOI: 10.3389/fimmu.2022.873560
  
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frontiersin.org/article/10.3389/fimmu.2022.873560/full
Mar 2022
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Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections

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1. scibot 06 Mar 2022
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.xcrm.2022.100557
  
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De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells

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1. scibot 05 Mar 2022
  
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  RRID:AB_468926
  
  DOI: 10.1186/s12943-022-01520-0
  
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link.springer.com/article/10.1186/s12943-022-01520-0
Dec 2021
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CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature

1
1. scibot 29 Dec 2021
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.ebiom.2021.103746
  
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Coenzyme A fuels T cell anti-tumor immunity

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1. scibot 08 Dec 2021
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.cmet.2021.11.010
  
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sciencedirect.com/science/article/pii/S1550413121005386
Jul 2021
elifesciences.org elifesciences.org

Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members

1
1. scibot 31 Jul 2021
  
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  RRID:AB_468926
  
  DOI: 10.7554/eLife.44360
  
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Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

1
1. scibot 29 Jul 2021
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.cell.2018.11.043
  
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cell.com/cell/fulltext/S0092-8674(18)31568-X
Feb 2021
elifesciences.org elifesciences.org

Stochastic asymmetric repartition of lytic machinery in dividing CD8+ T cells generates heterogeneous killing behavior

1
1. scibot 11 Feb 2021
  
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  RRID:AB_468926
  
  DOI: 10.7554/eLife.62691
  
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elifesciences.org/articles/62691
Sep 2020
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Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis

1
1. scibot 23 Sep 2020
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.celrep.2020.02.062
  
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Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration

1
1. scibot 17 Sep 2020
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.celrep.2019.12.083
  
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sciencedirect.com/science/article/pii/S2211124719317486
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Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation

1
1. scibot 13 Sep 2020
  
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  RRID:AB_468926
  
  DOI: 10.1016/j.cmet.2020.04.015
  
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Tumor organoid–T-cell coculture systems

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1. scibot 12 Sep 2020
  
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  RRID:AB_468926
  
  DOI: 10.1038/s41596-019-0232-9
  
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nature.com/articles/s41596-019-0232-9
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Clearance of apoptotic cells by mesenchymal stem cells contributes to immunosuppression via PGE2

1
1. scibot 03 Sep 2020
  
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  AB_468926
  
  DOI: 10.1016/j.ebiom.2019.06.016
  
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sciencedirect.com/science/article/pii/S2352396419303974
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_468926
  
  DOI: 10.7554/eLife.44360
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6456299/
Nov 2018
www-sciencedirect-com.ezp-prod1.hul.harvard.edu www-sciencedirect-com.ezp-prod1.hul.harvard.edu

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

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1. scibot 05 Nov 2018
  
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www-sciencedirect-com.ezp-prod1.hul.harvard.edu/science/article/pii/S0092867418309036
Nov 2017
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Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity

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1. scibot 08 Nov 2017
  
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  AB_468926
  
  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S1934590916304015