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SLC6A8-mediated creatine uptake suppresses ERK2-FSP1 signaling and induces ferroptosis in colorectal cancer

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116139
  
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sciencedirect.com/science/article/pii/S2211124725009106
Aug 2025
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An age-related decrease in leptin contributes to CD8+ T cell aging in the tumor microenvironment

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102310
  
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sciencedirect.com/science/article/pii/S2666379125003830
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Succinate preserves CD8+ T cell fitness to augment antitumor immunity

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1. scibot 15 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.07.017
  
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sciencedirect.com/science/article/pii/S1074761325003267
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Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control

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1. scibot 06 Aug 2025
  
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  DOI: 10.1016/j.cmet.2025.07.006
  
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sciencedirect.com/science/article/pii/S155041312500333X
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CTG-Initiated Cryptic Peptide Translation Up- and Downstream of a Canonical ATG Start Codon Is Enhanced by TLR Stimulation and Induces Tumor Regression in Mice

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1. scibot 05 Aug 2025
  
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  DOI: 10.1158/2326-6066.CIR-24-0467
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12314520/
Jun 2025
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Bispecific targeting of 4-1BB and CCR8 boosts antitumor immunity via Ti-Treg depletion and CD8+ activation

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112829
  
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sciencedirect.com/science/article/pii/S2589004225010909
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1. scibot 13 Jun 2025
  
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  DOI: 10.1158/2326-6066.cir-24-0467
  
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52.53.155.43/222b3bee495041e065bdee761a6ce36008a4c9e7/PDF-html.html
May 2025
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Dietary lipid overload creates a suppressive environment that impedes the antiviral functions of NK cells

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112396
  
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sciencedirect.com/science/article/pii/S2589004225006571
Mar 2025
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Therapeutic activation of IL-22-producing innate lymphoid cells enhances host defenses to Clostridioides difficile infection

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115438
  
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sciencedirect.com/science/article/pii/S2211124725002098
Feb 2025
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Dendritic cell phagosomes recruit GRASP55 for export of antigen-loaded MHC molecules

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115333
  
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sciencedirect.com/science/article/pii/S2211124725001044
Nov 2024
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ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma

1
1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114962
  
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sciencedirect.com/science/article/pii/S2211124724013135
Aug 2024
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Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance

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1. scibot 25 Aug 2024
  
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  DOI: 10.1016/j.xcrm.2024.101686
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11384939/
Jun 2024
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Gαz-independent and -dependent Improvements With EPA Supplementation on the Early Type 1 Diabetes Phenotype of NOD Mice

1
1. scibot 05 Jun 2024
  
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  RRID:AB_469504
  
  DOI: 10.1210/jendso/bvae100
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11146416/
May 2024
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A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification

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1. scibot 02 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.007
  
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sciencedirect.com/science/article/pii/S1074761324002127
Apr 2024
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CRISPR-Cas9 screening identifies INTS3 as an anti-apoptotic RNA-binding protein and therapeutic target for colorectal cancer

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1. scibot 28 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109676
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11043890/
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The trogocytosis of neutrophils on initial transplanted tumor in mice

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1. scibot 24 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109661
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11033691/
Mar 2024
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Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides

2
1. scibot 29 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113984
  
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2. scibot 29 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113984
  
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sciencedirect.com/science/article/pii/S2211124724003127
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NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment

2
1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113898
  
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2. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113898
  
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sciencedirect.com/science/article/pii/S2211124724002262
Feb 2024
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Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells

2
1. scibot 29 Feb 2024
  
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  DOI: 10.1016/j.immuni.2024.01.019
  
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  DOI: 10.1016/j.immuni.2024.01.019
  
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sciencedirect.com/science/article/pii/S1074761324000451
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Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells

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1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.cmet.2024.01.008
  
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sciencedirect.com/science/article/pii/S1550413124000081
Jan 2024
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Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity

1
1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.cmet.2023.12.016
  
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sciencedirect.com/science/article/pii/S1550413123004679
Dec 2023
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De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function

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1. scibot 21 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113518
  
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sciencedirect.com/science/article/pii/S2211124723015309
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Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure

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1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.immuni.2023.11.005
  
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sciencedirect.com/science/article/pii/S1074761323004879
Oct 2023
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Dietary fructose-mediated adipocyte metabolism drives antitumor CD8+ T cell responses

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1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.cmet.2023.09.011
  
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sciencedirect.com/science/article/pii/S1550413123003674
Aug 2023
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SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine

2
1. scibot 17 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112940
  
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  DOI: 10.1016/j.celrep.2023.112940
  
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52.53.155.43/746dceaaaecd8ad8008d9df523b985f7a77f181a/PIIS2211124723009518-html.html
Jul 2023
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LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer

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1. scibot 13 Jul 2023
  
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  DOI: 10.1016/j.devcel.2023.06.006
  
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sciencedirect.com/science/article/pii/S1534580723003040
May 2023
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Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity

1
1. scibot 27 May 2023
  
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  DOI: 10.1016/j.ccell.2023.04.016
  
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sciencedirect.com/science/article/pii/S1535610823001423
Apr 2023
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Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function

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1. scibot 19 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112419
  
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sciencedirect.com/science/article/pii/S2211124723004308
Mar 2023
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A monoclonal Trd chain supports the development of the complete set of functional γδ T cell lineages

1
1. scibot 16 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112253
  
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sciencedirect.com/science/article/pii/S2211124723002644
Feb 2023
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Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer

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1. scibot 24 Feb 2023
  
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  DOI: 10.1016/j.ccell.2023.01.004
  
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sciencedirect.com/science/article/pii/S1535610823000041
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OX40 agonism enhances PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum

1
1. scibot 16 Feb 2023
  
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  DOI: 10.1016/j.xcrm.2023.100939
  
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sciencedirect.com/science/article/pii/S2666379123000319
Dec 2022
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Alveolar macrophages instruct CD8+ T cell expansion by antigen cross-presentation in lung

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1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111828
  
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sciencedirect.com/science/article/pii/S221112472201720X
Oct 2022
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SYK coordinates neuroprotective microglial responses in neurodegenerative disease

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1. scibot 20 Oct 2022
  
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  DOI: 10.1016/j.cell.2022.09.030
  
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Cancer-specific T helper shared and neo-epitopes uncovered by expression of the MHC class II master regulator CIITA

1
1. scibot 12 Oct 2022
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2022.111485
  
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Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis

1
1. scibot 15 Sep 2022
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2022.111328
  
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Functional assessment of the cell-autonomous role of NADase CD38 in regulating CD8+ T cell exhaustion

1
1. scibot 21 May 2022
  
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  DOI: 10.1016/j.isci.2022.104347
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9117873/
Apr 2022
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Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity

1
1. scibot 13 Apr 2022
  
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  DOI: 10.1016/j.immuni.2022.03.013
  
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Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer

1
1. scibot 01 Apr 2022
  
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  DOI: 10.1016/j.immuni.2022.03.008
  
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sciencedirect.com/science/article/pii/S1074761322001315
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A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts

1
1. scibot 09 Mar 2022
  
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  DOI: 10.1016/j.immuni.2022.02.003
  
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Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2

1
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  RRID:AB_469504
  
  DOI: 10.1016/j.cell.2022.02.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8825346/
Nov 2021
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MicroRNA-29 specifies age-related differences in the CD8+ T cell immune response

1
1. scibot 10 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109969
  
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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

1
1. scibot 03 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109911
  
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Oct 2021
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The subunits of IL-12, originating from two distinct cells, can functionally synergize to protect against pathogen dissemination in vivo

1
1. scibot 13 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109816
  
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Aug 2021
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CXCL10+ peripheral activation niches couple preferred sites of Th1 entry with optimal APC encounter

1
1. scibot 15 Aug 2021
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2021.109523
  
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Untitled document

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  DOI: 10.1016/j.ebiom.2017.04.008
  
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ebiomedicine.com/article/S2352-3964(17)30151-2/abstract
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Loss of Zbtb32 in NOD mice does not significantly alter T cell responses.

2
1. scibot 08 Aug 2021
  
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  RRID:AB_469504
  
  DOI: 10.12688/f1000research.13864.2
  
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  RRID:AB_469504
  
  DOI: 10.12688/f1000research.13864.1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5909056/
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Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages

4
1. scibot 08 Aug 2021
  
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  AB_469504
  
  DOI: 10.1016/j.ebiom.2017.04.008
  
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  AB_469504
  
  DOI: 10.1016/j.ebiom.2017.04.008
  
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  AB_469504
  
  DOI: 10.1016/j.ebiom.2017.04.008
  
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  AB_469504
  
  DOI: 10.1016/j.ebiom.2017.04.008
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5405198/
Jul 2021
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Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages

1
1. scibot 30 Jul 2021
  
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  AB_469504
  
  DOI: 10.1016/j.ebiom.2017.04.008
  
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Loss of Zbtb32 in NOD mice does not significantly alter T cell responses.

2
1. scibot 29 Jul 2021
  
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  RRID:AB_469504
  
  DOI: 10.12688/f1000research.13864.2
  
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2. scibot 27 Jul 2021
  
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  RRID:AB_469504
  
  DOI: 10.12688/f1000research.13864.1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5909056/
May 2021
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Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology

1
1. scibot 28 May 2021
  
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  17-7311-82
  
  DOI: 10.1126/sciadv.abe4601
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8139596/
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Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease

1
1. scibot 14 May 2021
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.medj.2021.04.013
  
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sciencedirect.com/science/article/pii/S2666634021001628
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SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function

1
1. scibot 08 May 2021
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.molcel.2020.12.024
  
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sciencedirect.com/science/article/pii/S109727652030945X
Apr 2021
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The CD94/NKG2A inhibitory receptor educates uterine NK cells to optimize pregnancy outcomes in humans and mice

1
1. scibot 22 Apr 2021
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.immuni.2021.03.021
  
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sciencedirect.com/science/article/pii/S1074761321001333
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Low immunogenicity of malaria pre‐erythrocytic stages can be overcome by vaccination

1
1. scibot 17 Apr 2021
  
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  RRID:AB_469504
  
  DOI: 10.15252/emmm.202013390
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8033512/
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A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance

1
1. scibot 10 Apr 2021
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.immuni.2021.03.020
  
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sciencedirect.com/science/article/pii/S1074761321001321
Mar 2021
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Functional characterization of the dural sinuses as a neuroimmune interface

1
1. scibot 08 Mar 2021
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.cell.2020.12.040
  
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sciencedirect.com/science/article/pii/S0092867420317621
Feb 2021
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A Genome-wide CRISPR Screen Reveals a Role for the Non-Canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function

1
1. scibot 25 Feb 2021
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.immuni.2020.06.011
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7341821/
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Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity

1
1. scibot 24 Feb 2021
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.immuni.2018.12.020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6382412/
Dec 2020
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SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity

1
1. scibot 07 Dec 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2020.108468
  
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sciencedirect.com/science/article/pii/S2211124720314571
Sep 2020
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The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

1
1. scibot 23 Sep 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.immuni.2020.03.004
  
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sciencedirect.com/science/article/pii/S1074761320301175
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MicroRNA-9 Fine-Tunes Dendritic Cell Function by Suppressing Negative Regulators in a Cell-Type-Specific Manner

1
1. scibot 23 Sep 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2020.107585
  
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sciencedirect.com/science/article/pii/S2211124720305349
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Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

1
1. scibot 15 Sep 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.immuni.2020.04.014
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8360766/
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Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells

1
1. scibot 11 Sep 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.cmet.2020.03.003
  
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sciencedirect.com/science/article/pii/S1550413120301182
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Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection

1
1. scibot 04 Sep 2020
  
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  Anti- IFNγ
  
  DOI: 10.1016/j.celrep.2020.03.058
  
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sciencedirect.com/science/article/pii/S2211124720303831
Jan 2020
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The Sympathetic Nervous System Mitigates CNS Autoimmunity via β2-Adrenergic Receptor Signaling in Immune Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2019.08.042
  
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sciencedirect.com/science/article/pii/S2211124719310903
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Programming of Distinct Chemokine-Dependent and -Independent Search Strategies for Th1 and Th2 Cells Optimizes Function at Inflamed Sites

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  RRID:AB_469504
  
  DOI: 10.1016/j.immuni.2019.06.026
  
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sciencedirect.com/science/article/pii/S1074761319302961
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H3K4me1 Supports Memory-like NK Cells Induced by Systemic Inflammation

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1. scibot 13 Jan 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2019.11.043
  
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sciencedirect.com/science/article/pii/S2211124719315256
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Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products

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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2019.10.042
  
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sciencedirect.com/science/article/pii/S2211124719313567
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Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells

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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2019.10.018
  
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sciencedirect.com/science/article/pii/S221112471931318X
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Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.cmet.2019.05.016
  
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cell.com/cell-metabolism/fulltext/S1550-4131(19)30256-6
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Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function

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1. scibot 13 Jan 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2019.06.024
  
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sciencedirect.com/science/article/pii/S2211124719307909
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Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens

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1. scibot 13 Jan 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2019.08.038
  
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sciencedirect.com/science/article/pii/S2211124719310782
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IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties

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1. scibot 13 Jan 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.cmet.2019.01.006
  
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sciencedirect.com/science/article/pii/S1550413119300063
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.immuni.2018.12.020
  
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sciencedirect.com/science/article/pii/S1074761318305685
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Untitled document

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  RRID:AB_469504
  
  DOI: 10.1016/j.cmet.2019.01.019
  
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sciencedirect.com/science/article/pii/S1550413119300191
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Untitled document

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  RRID:AB_469504
  
  DOI: 10.1016/j.immuni.2019.01.003
  
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sciencedirect.com/science/article/pii/S1074761319300032
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Interstitial Migration of CD8αβ T Cells in the Small Intestine Is Dynamic and Is Dictated by Environmental Cues

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1. scibot 13 Jan 2020
  
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  RRID:AB_469504
  
  DOI: 10.1016/j.celrep.2019.02.034
  
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sciencedirect.com/science/article/pii/S2211124719302050
Nov 2018
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Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy

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sciencedirect.com/science/article/pii/S1074761317304235
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Developmental Origin Governs CD8+ T Cell Fate Decisions during Infection

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sciencedirect.com/science/article/pii/S009286741830641X
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Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S155041311830319X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation

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1. scibot 05 Nov 2018
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5911925/
Nov 2017
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Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages

1
1. scibot 08 Nov 2017
  
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  AB_469504
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5405198/
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Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages

1
1. scibot 08 Nov 2017
  
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  AB_469504
  
  Curator: @kaitlinsung
  
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sciencedirect.com/science/article/pii/S2352396417301512
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Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells

1
1. scibot 08 Nov 2017
  
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  AB_469504
  
  Curator: @jcabotaj
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4479795/

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