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A machine learning-based megakaryocyte identification system uncovers resident organs, markers, and functional diversity

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1. scibot 12 May 2026
  
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  DOI: 10.1016/j.devcel.2026.04.005
  
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sciencedirect.com/science/article/pii/S1534580726001528
Jan 2026
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Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116875
  
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sciencedirect.com/science/article/pii/S221112472501647X
Mar 2025
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PDF-html.html

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1. scibot 24 Mar 2025
  
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  DOI: 10.1101/2025.03.19.25323813
  
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52.53.155.43/c0adcb48d0c7767bb4cae1f3b62e518d05bfbccf/PDF-html.html
Sep 2024
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IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.cmet.2024.08.012
  
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sciencedirect.com/science/article/pii/S1550413124003644
Aug 2024
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Ing4-deficiency promotes a quiescent yet transcriptionally poised state in hematopoietic stem cells

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1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.isci.2024.110521
  
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sciencedirect.com/science/article/pii/S2589004224017462
Jun 2024
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Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti

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1. scibot 05 Jun 2024
  
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  DOI: 10.1016/j.cmet.2024.04.020
  
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sciencedirect.com/science/article/pii/S1550413124001761
Mar 2024
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Differentiation route determines the functional outputs of adult megakaryopoiesis

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1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.immuni.2024.02.006
  
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sciencedirect.com/science/article/pii/S1074761324000827
Nov 2023
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Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.ccell.2023.11.001
  
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sciencedirect.com/science/article/pii/S1535610823003665
Aug 2023
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Hematopoietic stem and progenitor cells confer cross-protective trained immunity in mouse models

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107596
  
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52.53.155.43/d7b070e8e28224284f601b7e5624dab532af26cc/PIIS2589004223016735-html.html
May 2023
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Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.stem.2022.06.012
  
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sciencedirect.com/science/article/pii/S1934590922002612
Feb 2023
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BATF2 promotes HSC myeloid differentiation by amplifying IFN response mediators during chronic infection

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1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.isci.2023.106059
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9942003/
Jan 2023
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Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.stem.2022.12.003
  
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sciencedirect.com/science/article/pii/S1934590922004878
Sep 2022
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Metronomic cyclophosphamide is more effective than a single dose in resistant tumours Cyclophosphamide depletes tumour infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma

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1. scibot 15 Sep 2022
  
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  DOI: 10.1016/j.isci.2022.104995
  
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sciencedirect.com/science/article/pii/S2589004222012676
Jul 2022
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Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling

1
1. scibot 14 Jul 2022
  
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  DOI: 10.1016/j.immuni.2022.06.007
  
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sciencedirect.com/science/article/pii/S1074761322002801
Jun 2022
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Very-low-density lipoprotein receptor-enhanced lipid metabolism in pancreatic stellate cells promotes pancreatic fibrosis

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1. scibot 24 Jun 2022
  
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  DOI: 10.1016/j.immuni.2022.06.001
  
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sciencedirect.com/science/article/pii/S1074761322002394
Apr 2022
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Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation

1
1. scibot 21 Apr 2022
  
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  RRID:AB_469663
  
  DOI: 10.1016/j.cell.2016.07.026
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5555589/
Jan 2022
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External signals regulate continuous transcriptional states in hematopoietic stem cells

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1. scibot 07 Jan 2022
  
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  RRID:AB_469663
  
  DOI: 10.7554/eLife.66512
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8700284/
Sep 2021
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Mesenchymal stem cells attenuate liver fibrosis by targeting Ly6Chi/lo macrophages through activating the cytokine-paracrine and apoptotic pathways

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1. scibot 28 Sep 2021
  
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  RRID:AB_469663
  
  DOI: 10.1038/s41420-021-00584-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8437974/
Aug 2021
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Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA

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1. scibot 25 Aug 2021
  
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  DOI: 10.1016/j.celrep.2021.109537
  
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sciencedirect.com/science/article/pii/S2211124721009712
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Untitled document

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1. scibot 02 Aug 2021
  
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  RRID:AB_469663
  
  DOI: 10.1016/j.stem.2018.10.004
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6224657/
May 2021
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Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells

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1. scibot 29 May 2021
  
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  DOI: 10.1016/j.immuni.2021.05.008
  
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sciencedirect.com/science/article/pii/S1074761321002144
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Chronic infection drives Dnmt3a-loss-of-function clonal hematopoiesis via IFNγ signaling

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1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2021.03.002
  
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sciencedirect.com/science/article/pii/S1934590921001089
Dec 2020
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Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2

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1. scibot 23 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108530
  
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sciencedirect.com/science/article/pii/S2211124720315199
Sep 2020
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Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia

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1. scibot 30 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.108200
  
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sciencedirect.com/science/article/pii/S221112472031189X
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Differential Alternative Polyadenylation Landscapes Mediate Hematopoietic Stem Cell Activation and Regulate Glutamine Metabolism

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1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.stem.2020.03.003
  
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sciencedirect.com/science/article/pii/S1934590920300953
Jan 2020
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Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.stem.2019.06.003
  
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sciencedirect.com/science/article/pii/S193459091930267X
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2018.12.012
  
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sciencedirect.com/science/article/pii/S1074761318305600
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Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.05.002
  
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sciencedirect.com/science/article/pii/S1074761319302018
Nov 2018
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Untitled document

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sciencedirect.com/science/article/pii/S1934590918304855
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Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations

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sciencedirect.com/science/article/pii/S1535610818303088
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LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1931312818303780
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Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1934590918301644
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Commensal Microbes Induce Serum IgA Responses that Protect against Polymicrobial Sepsis

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1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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  RRID:AB_469663 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1931312818300404
Nov 2017
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Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation

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1. scibot 08 Nov 2017
  
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  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S0092867416309722