504 Matching Annotations
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  2. 52.53.155.43 52.53.155.43
    Characterization of 35 novel NR5A1/SF-1 variants identified in individuals with atypical sexual development: The SF1next study
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    1. scibot 19 Apr 2024
      RRID:AB_476692

      DOI: 10.1210/clinem/dgae251

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  3. www.ahajournals.org www.ahajournals.org
    New Loss-of-Function Mutations in PCSK9 Reduce Plasma LDL Cholesterol
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    1. scibot 18 Apr 2024
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      DOI: 10.1161/ATVBAHA.122.318839

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    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
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    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114094

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      DOI: 10.1016/j.celrep.2024.114094

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    sciencedirect.com/science/article/pii/S2211124724004224
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    Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis
    1
    1. scibot 18 Apr 2024
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      DOI: 10.1038/s44318-023-00008-x

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  6. Apr 2024
  7. www.biorxiv.org www.biorxiv.org
    Age-dependent regulation of axoglial interactions and behavior by oligodendrocyte AnkyrinG
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    1. scibot 12 Apr 2024
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      DOI: 10.1101/2024.04.01.587609

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    biorxiv.org/content/10.1101/2024.04.01.587609v1
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    Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding
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      DOI: 10.1038/s41593-024-01615-5

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    nature.com/articles/s41593-024-01615-5
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    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
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    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.stem.2024.03.003

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    sciencedirect.com/science/article/pii/S1934590924000845
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    New Loss-of-Function Mutations in PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Reduce Plasma LDL (Low-Density Lipoprotein) Cholesterol
    1
    1. scibot 04 Apr 2024
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      DOI: 10.1161/ATVBAHA.122.318839

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    ahajournals.org/doi/abs/10.1161/ATVBAHA.122.318839
  11. Mar 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides
    2
    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113984

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      DOI: 10.1016/j.celrep.2024.113984

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    sciencedirect.com/science/article/pii/S2211124724003127
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating the role of an immediate early gene FOS as a potential regulator of autophagic response to hypoglycemia in embryonic hypothalamic neurons
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    1. scibot 19 Mar 2024
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      DOI: 10.1111/cts.13749

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    ncbi.nlm.nih.gov/pmc/articles/PMC10941580/
  14. www.embopress.org www.embopress.org
    Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis
    3
    1. scibot 15 Mar 2024
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      DOI: 10.1038/s44318-023-00008-x

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      DOI: 10.1038/s44318-023-00008-x

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      DOI: 10.1038/s44318-023-00008-x

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    embopress.org/doi/full/10.1038/s44318-023-00008-x
  15. www.embopress.org www.embopress.org
    Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis
    1
    1. scibot 15 Mar 2024
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      DOI: 10.1038/s44318-023-00008-x

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    embopress.org/doi/10.1038/s44318-023-00008-x
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pla2g12b drives expansion of triglyceride-rich lipoproteins
    1
    1. scibot 12 Mar 2024
      RRID:AB_476692

      DOI: 10.1038/s41467-024-46102-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920679/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXO1 stimulates tip cell-enriched gene expression in endothelial cells
    1
    1. scibot 07 Mar 2024
      RRID:AB_476692

      DOI: 10.1016/j.isci.2024.109161

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    ncbi.nlm.nih.gov/pmc/articles/PMC10914484/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Contactin-associated protein-like 2 (CNTNAP2) mutations impair the essential α-secretase cleavages, leading to autism-like phenotypes
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    1. scibot 06 Mar 2024
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      DOI: 10.1038/s41392-024-01768-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10904759/
  19. www.sciencedirect.com www.sciencedirect.com
    NRG1-ErbB4 signaling in the medial amygdala controls mating motivation in adult male mice
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      DOI: 10.1016/j.celrep.2024.113905

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      DOI: 10.1016/j.celrep.2024.113905

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    sciencedirect.com/science/article/pii/S221112472400233X
  20. Feb 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting ABCG1 and SREBP-2 mediated cholesterol homeostasis ameliorates Zika virus induced ocular pathology
    1
    1. scibot 28 Feb 2024
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      DOI: 10.1016/j.isci.2024.109088

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    ncbi.nlm.nih.gov/pmc/articles/PMC10884761/
  22. 52.53.155.43 52.53.155.43
    AURKA enhances the glycolysis and development of ovarian endometriosis through ERβ
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    1. scibot 28 Feb 2024
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      DOI: 10.1210/endocr/bqae018

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  23. 52.53.155.43 52.53.155.43
    meng-et-al-2023-new-loss-of-function-mutations-in-pcsk9-reduce-plasma-ldl-cholesterol-html.html
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    1. scibot 27 Feb 2024
      AB_476692

      DOI: 10.1161/atvbaha.122.318839

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    52.53.155.43/6dc7bb5c3defb3dc565dda6223aa90187b2786e1/meng-et-al-2023-new-loss-of-function-mutations-in-pcsk9-reduce-plasma-ldl-cholesterol-html.html
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative modelling and analysis of signalling crosstalk reveal molecular switches coordinating YAP transcriptional activities
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    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.isci.2024.109031

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    ncbi.nlm.nih.gov/pmc/articles/PMC10877689/
  25. 52.53.155.43 52.53.155.43
    Regulation of the intestinal Na+/H+ exchanger NHE3 by AMP-activated kinase is dependent on phosphorylation of NHE3 at S555 and S563
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    1. scibot 22 Feb 2024
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      DOI: 10.1152/ajpcell.00540.2023

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    52.53.155.43/f69a85cf28386bd1400aa251e3a5d55dee473eb1/han-et-al-2024-regulation-of-the-intestinal-na-h-exchanger-nhe3-by-amp-activated-kinase-is-dependent-on-phosphorylation-html.html
  26. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Increased levels of advanced oxidation protein products (AOPPs) were associated with nociceptive behavior and clinical scores in an experimental progressive autoimmune encephalomyelitis model (PMS-EAE)
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    1. scibot 22 Feb 2024
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      DOI: 10.1111/jnc.16081

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16081
  27. www.sciencedirect.com www.sciencedirect.com
    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
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    1. scibot 21 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.022

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    sciencedirect.com/science/article/pii/S1097276524000893
  28. www.sciencedirect.com www.sciencedirect.com
    ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion
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    1. scibot 16 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113794

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    sciencedirect.com/science/article/pii/S2211124724001220
  29. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Role of paraoxonase 3 in regulating ENaC-mediated Na+ transport in the distal nephron
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    1. scibot 15 Feb 2024
      AB_476

      DOI: 10.1113/JP285034

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  30. link.springer.com link.springer.com
    The human OPA1delTTAG mutation induces adult onset and progressive auditory neuropathy in mice
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    1. scibot 14 Feb 2024
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      DOI: 10.1007/s00018-024-05115-4

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    link.springer.com/article/10.1007/s00018-024-05115-4
  31. link.springer.com link.springer.com
    Mechanical activation and expression of HSP27 in epithelial ovarian cancer
    1
    1. scibot 07 Feb 2024
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      DOI: 10.1038/s41598-024-52992-7

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    link.springer.com/article/10.1038/s41598-024-52992-7
  32. www.mdpi.com www.mdpi.com
    Oxidative Stress Plays an Important Role in Glutamatergic Excitotoxicity-Induced Cochlear Synaptopathy: Implication for Therapeutic Molecules Screening
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      DOI: 10.3390/antiox13020149

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    mdpi.com/2076-3921/13/2/149
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 mediated Y-chromosome elimination affects human cells transcriptome
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    1. scibot 02 Feb 2024
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      DOI: 10.1186/s13578-024-01198-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10829266/
  34. Jan 2024
  35. www.sciencedirect.com www.sciencedirect.com
    Downregulation of the kidney glucagon receptor, essential for renal function and systemic homeostasis, contributes to chronic kidney disease
    1
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      DOI: 10.1016/j.cmet.2023.12.024

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    sciencedirect.com/science/article/pii/S1550413123004758
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The intracellular C-terminus confers compartment-specific targeting of voltage-gated Ca2+ channels
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      DOI: 10.1101/2023.12.23.573183

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  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival
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      DOI: 10.1002/advs.202301476

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  38. www.sciencedirect.com www.sciencedirect.com
    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
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      DOI: 10.1016/j.celrep.2023.113626

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    sciencedirect.com/science/article/pii/S2211124723016376
  39. Dec 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes
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    1. scibot 22 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113603

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    sciencedirect.com/science/article/pii/S2211124723016157
  41. www.sciencedirect.com www.sciencedirect.com
    Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk
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    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113595

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    sciencedirect.com/science/article/pii/S2211124723016078
  42. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18
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    1. scibot 17 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113560

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    sciencedirect.com/science/article/pii/S2211124723015723
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mir324 knockout regulates the structure of dendritic spines and impairs hippocampal long-term potentiation
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      DOI: 10.1038/s41598-023-49134-w

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    Generation of iPSC lines with SLC16A2:G401R or SLC16A2 knock out
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    Purification and characterization of different proteasome species from mammalian cells
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  46. Nov 2023
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    Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity
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    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
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  49. Oct 2023
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    HDL inhibits pancreatic acinar cell NLRP3 inflammasome activation and protect against acinar cell pyroptosis in acute pancreatitis
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    Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WIP1 is a novel specific target for growth hormone action
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    The role of HIF-1α/HO-1 pathway in hippocampal neuronal ferroptosis in epilepsy
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells
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  55. Sep 2023
  56. link.springer.com link.springer.com
    Use of Native-PAGE for the Identification of Epichaperomes in Cell Lines
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of a human Tropomyosin 1 knockout iPSC line
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    Anillin forms linear structures and facilitates furrow ingression after septin and formin depletion
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    LncRNA THUMPD3-AS1 promotes invasion and EMT in gastric cancer by regulating the miR-1297/BCAT1 pathway
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  60. Aug 2023
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    Mouse embryonic stem cells embody organismal-level cold resistance
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  62. Jul 2023
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    A method to study human synaptic protein-protein interactions by using Flow Cytometry coupled to Proximity ligation assay (Syn-FlowPLA)
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  64. 52.53.155.43 52.53.155.43
    Generation of a human Tropomyosin 1 knockout iPSC line
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    DIRAS3 enhances RNF19B-mediated RAC1 ubiquitination and degradation in non-small-cell lung cancer cells
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    Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration
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    DHA Supplementation during Pregnancy in Women with Obesity Normalizes IGF2R Levels in the Placenta of Male Newborns
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    Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production
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    Metabolic regulation of CTCF expression and chromatin association dictates starvation response in mice and flies
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  70. Jun 2023
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    Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice
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    ECPAS/Ecm29-mediated 26S proteasome disassembly is an adaptive response to glucose starvation
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    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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  74. www.embopress.org www.embopress.org
    Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response
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    The Sar1 GTPase is dispensable for COPII-dependent cargo export from the ER
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    The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
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  77. May 2023
  78. www.science.org www.science.org
    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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    Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex
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    Salivary gland cancer organoids are valid for preclinical genotype-oriented medical precision trials
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
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    Vitamin K-dependent carboxylation regulates Ca2+ flux and adaptation to metabolic stress in β cells
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    Within the Ischemic Penumbra, Sub-Cellular Compartmentalization of Heat Shock Protein 70 Overlaps with Autophagy Proteins and Fails to Merge with Lysosomes
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    A disease-associated mutation in thyroid hormone receptor α1 causes hearing loss and sensory hair cell patterning defects in mice
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  85. Apr 2023
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    TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice
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    Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy
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    The ulcerative colitis-associated gene FUT8 regulates the quantity and quality of secreted mucins
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    Development of Adenovirus-Based Covid-19 Vaccine Candidate in Indonesia
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    Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures
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  91. www.nature.com www.nature.com
    The RNA-binding protein landscapes differ between mammalian organs and cultured cells
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    Identification of a comprehensive alternative splicing function during epithelial-mesenchymal transition
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    MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer
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    The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome
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      DOI: 10.1016/j.immuni.2023.03.003

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  95. link.springer.com link.springer.com
    Development of myelin in fetal and postnatal neocortex of the pig, the European wild boar Sus scrofa
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      DOI: 10.1007/s00429-023-02633-y

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  96. Mar 2023
  97. www.sciencedirect.com www.sciencedirect.com
    Ketone bodies promote stroke recovery via GAT-1-dependent cortical network remodeling
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    SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective dysfunction of fast-spiking inhibitory interneurons and disruption of perineuronal nets in a tauopathy mouse model
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    m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis
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    Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma
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    Sustained oncogenic signaling in the cytostatic state enables targeting of non-proliferating persistent cancer cells
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  104. onlinelibrary.wiley.com onlinelibrary.wiley.com
    COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by upregulating Krox20
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurovascular development in Pten and Tsc2 mouse mutants
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  106. Feb 2023
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    Protein composition of axonal dopamine release sites in the striatum
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    Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity
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    PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle
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  110. Jan 2023
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    Neurexins in serotonergic neurons regulate neuronal survival, serotonin transmission, and complex mouse behaviors
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    Abl2 Kinase Differentially Regulates iGluRs Current Activity and Synaptic Localization
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CoQ Regulates Brown Adipose Tissue Respiration and Uncoupling Protein 1 Expression
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    CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis
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    CNTNAP2 Protein Is Degraded by the Ubiquitin–Proteasome System and the Macroautophagy-Lysosome Pathway
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      DOI: 10.1007/s12035-023-03227-9

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    Dietary Zinc Differentially Regulates the Effects of the GPR39 Receptor Agonist, TC-G 1008, in the Maximal Electroshock Seizure Test and Pentylenetetrazole-Kindling Model of Epilepsy
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    TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer
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    Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer
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    Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy
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  120. Dec 2022
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    Progesterone receptor mediated regulation of cellular glucose and 18F-fluorodeoxyglucose uptake in breast cancer
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      DOI: 10.1210/jendso/bvac186

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    Chromosomal instability-associated MAT1 lncRNA insulates MLL1-guided histone methylation and accelerates tumorigenesis
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    Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer
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    Establishment of a human embryonic stem cell line, WAe009-A-99, with constitutive expression of the dCas9-p300 fusion protein
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  125. Nov 2022
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    Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis
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    Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2
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    Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis
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  129. www.nature.com www.nature.com
    R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations
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  130. elifesciences.org elifesciences.org
    Contrasting effects of Ksr2, an obesity gene, on trabecular bone volume and bone marrow adiposity
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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell intrinsic TIM-3 induces glioblastoma progression
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  132. Oct 2022
  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Iron regulatory protein (IRP)–mediated iron homeostasis is critical for neutrophil development and differentiation in the bone marrow
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    Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation
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    Opposing roles of ZEB1 in the cytoplasm and nucleus control cytoskeletal assembly and YAP1 activity
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    Two independent respiratory chains adapt OXPHOS performance to glycolytic switch
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  137. Sep 2022
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    Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells
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    FOXA1 regulates alternative splicing in prostate cancer
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    SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA
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    Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis
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      DOI: 10.1080/15548627.2022.2100105

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    Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diagnostic and prognostic potential of the novel biomarker nuclear cap binding protein subunit 2 (NCBP2) in colon adenocarcinoma
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A
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  145. Aug 2022
  146. 52.53.155.43 52.53.155.43
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      DOI: 10.1158/0008-5472.CAN-21-2908

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  147. www.sciencedirect.com www.sciencedirect.com
    Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation
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    Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway
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    The endoplasmic reticulum membrane complex promotes proteostasis of GABAA receptors
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    sciencedirect.com/science/article/pii/S2589004222010264
  150. Jul 2022
  151. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TREM2-induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology
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      DOI: 10.1111/bpa.13108

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  152. www.sciencedirect.com www.sciencedirect.com
    Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy
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    Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover
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    sciencedirect.com/science/article/pii/S1534580722004518
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    Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
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  155. Jun 2022
  156. 52.53.155.43 52.53.155.43
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  157. www.sciencedirect.com www.sciencedirect.com
    Granger-causal inference of the lamellipodial actin regulator hierarchy by live cell imaging without perturbation
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    sciencedirect.com/science/article/pii/S2405471222002241
  158. May 2022
  159. www.sciencedirect.com www.sciencedirect.com
    Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells
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    Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia
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    Chromatin remodeling is restricted by transient GATA6 binding during iPSC differentiation to definitive endoderm
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    sciencedirect.com/science/article/pii/S2589004222005703
  162. www.sciencedirect.com www.sciencedirect.com
    HIV Tat and cocaine interactively alter genome-wide DNA methylation and gene expression and exacerbate learning and memory impairments
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    sciencedirect.com/science/article/pii/S2211124722005290
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    Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy
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    sciencedirect.com/science/article/pii/S2211124722005630
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    SETD4-mediated KU70 methylation suppresses apoptosis
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    The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62
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    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
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    ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene body methylation of the lymphocyte-specific gene CARD11 results in its overexpression and regulates cancer mTOR signaling
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      DOI: 10.1158/1541-7786.MCR-20-0753

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  169. Apr 2022
  170. www.sciencedirect.com www.sciencedirect.com
    Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells
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    Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity
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    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Nicotinamide Phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immune competence and spleen size scale with colony status in the naked mole-rat
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    The GADD45G/p38 MAPK/CDC25B signaling pathway enhances neurite outgrowth by promoting microtubule polymerization
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    Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis
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  177. Mar 2022
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport
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      DOI: 10.1091/mbc.E21-06-0286

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    Notch-mediated lactate metabolism regulates MDSC development through the Hes1/MCT2/c-Jun axis
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  180. aacrjournals.org aacrjournals.org
    MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
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    aacrjournals.org/cancerrescommun/article/2/2/110/681605/MYC-Inhibition-Halts-Metastatic-Breast-Cancer
  181. academic.oup.com academic.oup.com
    Fibroblast growth factor 13 is involved in the pathogenesis of temporal lobe epilepsy
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  182. Feb 2022
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rebuilding essential active zone functions within a synapse
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      DOI: 10.1016/j.neuron.2022.01.026

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  184. www.sciencedirect.com www.sciencedirect.com
    Ligand-mediated PAI-1 inhibition in a mouse model of peritoneal carcinomatosis
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    Aberrant cyclin C nuclear release induces mitochondrial fragmentation and dysfunction in MED13L syndrome fibroblasts
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  186. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
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      DOI: 10.1016/j.immuni.2022.01.003

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  187. www.sciencedirect.com www.sciencedirect.com
    A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis
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      DOI: 10.1016/j.cmet.2022.01.004

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    sciencedirect.com/science/article/pii/S1550413122000043
  188. Jan 2022
  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alzheimer’s genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner
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    1. scibot 28 Jan 2022
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      DOI: 10.1038/s41380-020-00926-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC8758496/
  190. www.molbiolcell.org www.molbiolcell.org
    Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport
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    1. scibot 28 Jan 2022
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      DOI: 10.1091/mbc.E21-06-0286

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  191. www.sciencedirect.com www.sciencedirect.com
    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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      DOI: 10.1016/j.ccell.2021.12.009

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    sciencedirect.com/science/article/pii/S1535610821006620
  192. www.sciencedirect.com www.sciencedirect.com
    Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors
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      DOI: 10.1016/j.celrep.2021.110278

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  193. www.sciencedirect.com www.sciencedirect.com
    Innate immune sensing of influenza A viral RNA through IFI16 promotes pyroptotic cell death
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      DOI: 10.1016/j.isci.2021.103714

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  194. 52.53.155.43 52.53.155.43
    en.2019-00132-html.html
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      DOI: 10.1210/en.2019-00132

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  195. link.springer.com link.springer.com
    The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects
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      DOI: 10.1186/s40478-021-01285-5

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  196. Dec 2021
  197. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Behavioural and neurochemical effects after repeated administration of N-ethylpentylone (ephylone) in mice
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      DOI: 10.1111/jnc.15542

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15542
  198. www.nature.com www.nature.com
    KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma
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      DOI: 10.1038/s41467-021-27502-2

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  199. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel localizations of TRPC5 channels suggest novel and unexplored roles: A study in the chick embryo brain
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      DOI: 10.1002/dneu.22857

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  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of ATM induces hypersensitivity to proton irradiation by upregulating toxic end joining
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      DOI: 10.1158/0008-5472.CAN-20-2960

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  201. www.sciencedirect.com www.sciencedirect.com
    Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage
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      DOI: 10.1016/j.celrep.2021.110068

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    Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation
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  203. www.nature.com www.nature.com
    Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
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      DOI: 10.1038/s42003-021-02842-3

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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arl4c promotes the growth and drug resistance of pancreatic cancer by regulating tumor-stromal interactions
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      DOI: 10.1016/j.isci.2021.103400

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  205. Nov 2021
  206. www.sciencedirect.com www.sciencedirect.com
    Continued Androgen Signalling Inhibition improves Cabazitaxel Efficacy in Prostate Cancer
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      RRID:AB_476692

      DOI: 10.1016/j.ebiom.2021.103681

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    sciencedirect.com/science/article/pii/S2352396421004758
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    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
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      DOI: 10.1016/j.celrep.2021.109979

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    Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling
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      DOI: 10.1016/j.celrep.2021.109989

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    sciencedirect.com/science/article/pii/S2211124721014686
  209. Oct 2021
  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers
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      DOI: 10.1158/0008-5472.CAN-21-1545

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  211. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
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      DOI: 10.1371/journal.ppat.1009412

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    SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling
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      DOI: 10.1016/j.cub.2021.09.022

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  213. Sep 2021
  214. www.sciencedirect.com www.sciencedirect.com
    PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis
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      DOI: 10.1016/j.molcel.2021.08.039

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    Myosin-X and talin modulate integrin activity at filopodia tips
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      DOI: 10.1016/j.celrep.2021.109716

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  216. www.sciencedirect.com www.sciencedirect.com
    Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter
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      DOI: 10.1016/j.chembiol.2021.07.016

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    KDM6B epigenetically regulated-interleukin-6 expression in the dorsal root ganglia and spinal dorsal horn contributes to the development and maintenance of neuropathic pain following peripheral nerve injury in male rats
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    Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease
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      DOI: 10.1016/j.celrep.2021.109636

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  219. Aug 2021
  220. www.sciencedirect.com www.sciencedirect.com
    Generation and characterization of an endogenously tagged SPG11- human iPSC line by CRISPR/Cas9 mediated knock-in
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    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
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      DOI: 10.1016/j.ccell.2021.07.006

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    sciencedirect.com/science/article/pii/S1535610821003834
  222. www.nature.com www.nature.com
    Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system
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      DOI: 10.1038/s41467-021-24821-2

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  223. www.biorxiv.org www.biorxiv.org
    STXBP5/tomosyn regulates both the small Rho GTPase and the surface expression of AMPA receptors to control the dendritic stability of neurons
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      DOI: 10.1101/617845

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  224. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1523/JNEUROSCI.3045-16.2017

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  225. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.cell.2019.01.017

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  226. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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