144 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity
    1
    1. scibot 11 Nov 2024
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      DOI: 10.1016/j.stem.2024.10.007

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    sciencedirect.com/science/article/pii/S1934590924003692
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCRR regulate MYZAP-PKP2-Nav1.5 signaling pathway in atrial fibrillation following myocardial infarction
    1
    1. scibot 10 Nov 2024
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      DOI: 10.1016/j.isci.2024.111102

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    pmc.ncbi.nlm.nih.gov/articles/PMC11539591/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Virtual drug screen reveals context-dependent inhibition of cardiomyocyte hypertrophy
    1
    1. scibot 07 Nov 2024
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      DOI: 10.1111/bph.16163

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    pmc.ncbi.nlm.nih.gov/articles/PMC10592153/
  5. Oct 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cardiovascular Complications of Pregnancy: Effects of maternal hypothyroidism on postnatal cardiomyocyte proliferation and cardiac disease responses of the progeny
    1
    1. scibot 03 Oct 2024
      RRID:AB_476766

      DOI: 10.1152/ajpheart.00320.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10659327/
  7. Sep 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic remodeling of Septin structures fine-tunes myogenic differentiation
    1
    1. scibot 12 Sep 2024
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      DOI: 10.1016/j.isci.2024.110630

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    ncbi.nlm.nih.gov/pmc/articles/PMC11380178/
  9. www.sciencedirect.com www.sciencedirect.com
    Modeling the atrioventricular conduction axis using human pluripotent stem cell-derived cardiac assembloids
    1
    1. scibot 11 Sep 2024
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      DOI: 10.1016/j.stem.2024.08.008

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    sciencedirect.com/science/article/pii/S1934590924002947
  10. www.sciencedirect.com www.sciencedirect.com
    A broadly applicable method for quantifying cardiomyocyte cell division identifies proliferative events following myocardial infarction
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.crmeth.2024.100860

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    sciencedirect.com/science/article/pii/S2667237524002388
  11. Aug 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Generation of a heterozygous Calsequestrin 2 F189L iPSC line (UMGi158-B) by CRISPR/Cas9 genome editing to investigate the cardiac pathophysiology of Takotsubo Syndrome and Catecholaminergic Polymorphic ventricular Tachycardia
    1
    1. scibot 27 Aug 2024
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    sciencedirect.com/science/article/pii/S1873506124002368
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    A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.stem.2024.07.006

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    sciencedirect.com/science/article/pii/S193459092400256X
  14. Jul 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114448

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    sciencedirect.com/science/article/pii/S2211124724007770
  16. www.sciencedirect.com www.sciencedirect.com
    Dystrophin deficiency impairs cell junction formation during embryonic myogenesis from pluripotent stem cells
    1
    1. scibot 10 Jul 2024
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      DOI: 10.1016/j.isci.2024.110242

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    sciencedirect.com/science/article/pii/S2589004224014676
  17. Jun 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substrate mechanics unveil early structural and functional pathology in iPSC micro-tissue models of hypertrophic cardiomyopathy
    1
    1. scibot 08 Jun 2024
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      DOI: 10.1016/j.isci.2024.109954

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    ncbi.nlm.nih.gov/pmc/articles/PMC11141149/
  19. www.sciencedirect.com www.sciencedirect.com
    Macrophages enhance contractile force in iPSC-derived human engineered cardiac tissue
    1
    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114302

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    sciencedirect.com/science/article/pii/S2211124724006302
  20. Apr 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dystrophin deficiency impairs cell junction formation during embryonic myogenesis
    1
    1. scibot 28 Apr 2024
      RRID:AB_476766

      DOI: 10.1101/2023.12.05.569919

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    ncbi.nlm.nih.gov/pmc/articles/PMC10723310/
  22. www.sciencedirect.com www.sciencedirect.com
    Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development
    1
    1. scibot 12 Apr 2024
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      DOI: 10.1016/j.stem.2024.03.011

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    sciencedirect.com/science/article/pii/S1934590924000924
  23. Mar 2024
  24. www.cell.com www.cell.com
    Myoglobin modulates the Hippo pathway to promote cardiomyocyte differentiation.
    3
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109146

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      DOI: 10.1016/j.isci.2024.109146

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    3. scibot 02 Mar 2024
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      DOI: 10.1016/j.isci.2024.109146

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    cell.com/iscience/abstract/S2589-0042(24)00367-5
  25. Feb 2024
  26. www.sciencedirect.com www.sciencedirect.com
    The Mas agonist CGEN-856S prevents Ang II induced cardiomyocyte hypertrophy via nitric oxide production
    2
    1. scibot 29 Feb 2024
      RRID:AB_476766

      DOI: 10.1016/j.peptides.2024.171182

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      RRID:AB_476766

      DOI: 10.1016/j.peptides.2024.171182

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    sciencedirect.com/science/article/pii/S0196978124000354
  27. www.biorxiv.org www.biorxiv.org
    Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies
    1
    1. scibot 15 Feb 2024
      RRID:AB_476766

      DOI: 10.1101/2024.02.01.578471

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    biorxiv.org/content/10.1101/2024.02.01.578471v1
  28. www.sciencedirect.com www.sciencedirect.com
    Generation of CRISPR/Cas9 edited human induced pluripotent stem cell line carrying the heterozygous p.H695VfsX5 frameshift mutation in the exon 10 of the PKP2 gene
    1
    1. scibot 15 Feb 2024
      RRID:AB_476766

      DOI: 10.1016/j.scr.2024.103341

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    sciencedirect.com/science/article/pii/S1873506124000394
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human iPSC-derived closed-loop cardiac tissue for drug assessment
    1
    1. scibot 11 Feb 2024
      RRID:AB_476766

      DOI: 10.1016/j.isci.2024.108992

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    ncbi.nlm.nih.gov/pmc/articles/PMC10850789/
  30. Jan 2024
  31. www.cell.com www.cell.com
    Epigenetic regulator RNF20 underlies temporal hierarchy of gene expression to regulate postnatal cardiomyocyte polarization
    1
    1. scibot 25 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113416

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    cell.com/cell-reports/abstract/S2211-1247(23)01428-6
  32. Dec 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Generation of CRISPR-Cas9 edited human induced pluripotent stem cell line carrying BAG3 V468M mutation in its BAG domain
    1
    1. scibot 29 Dec 2023
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      DOI: 10.1016/j.scr.2023.103294

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    sciencedirect.com/science/article/pii/S1873506123002805
  34. www.sciencedirect.com www.sciencedirect.com
    Generation of a fluorescent oligodendrocyte reporter line in human induced pluripotent stem cells
    1
    1. scibot 29 Dec 2023
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      DOI: 10.1016/j.scr.2023.103295

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    sciencedirect.com/science/article/pii/S1873506123002817
  35. www.sciencedirect.com www.sciencedirect.com
    HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function
    2
    1. scibot 17 Dec 2023
      RRID: AB_476766

      DOI: 10.1016/j.devcel.2023.11.012

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    2. scibot 17 Dec 2023
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      DOI: 10.1016/j.devcel.2023.11.012

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    sciencedirect.com/science/article/pii/S153458072300610X
  36. www.sciencedirect.com www.sciencedirect.com
    Generation of Pelizaeus-Merzbacher disease (PMD) mutant (PLP1-C33Y) in induced pluripotent stem cell (iPSC) by CRISPR/Cas9 genome editing
    1
    1. scibot 14 Dec 2023
      RRID:AB_476766

      DOI: 10.1016/j.scr.2023.103276

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    sciencedirect.com/science/article/pii/S1873506123002623
  37. www.sciencedirect.com www.sciencedirect.com
    Multi-chamber cardioids unravel human heart development and cardiac defects
    1
    1. scibot 02 Dec 2023
      RRID:AB_476766

      DOI: 10.1016/j.cell.2023.10.030

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    sciencedirect.com/science/article/pii/S0092867423011819
  38. Nov 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Generation of heart and vascular system in rodents by blastocyst complementation
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.devcel.2023.10.008

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    sciencedirect.com/science/article/pii/S153458072300552X
  40. www.sciencedirect.com www.sciencedirect.com
    Generation of induced pluripotent stem cell line (TMOi001-A-11) carrying a homozygous deletion in the synemin gene using CRISPR/Cas9
    1
    1. scibot 28 Nov 2023
      RRID:AB_476766

      DOI: 10.1016/j.scr.2023.103254

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    sciencedirect.com/science/article/pii/S1873506123002404
  41. Oct 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Creation of an iPSC-Based Skeletal Muscle Model of McArdle Disease Harbouring the Mutation c.2392T>C (p.Trp798Arg) in the PYGM Gene
    1
    1. scibot 06 Oct 2023
      RRID:AB_476766

      DOI: 10.3390/biomedicines11092434

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    ncbi.nlm.nih.gov/pmc/articles/PMC10525199/
  43. Aug 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Generation of a homozygous CRYAB p.Arg120Gly mutant (UKEi001-A-1) from a human iPSC line
    1
    1. scibot 27 Aug 2023
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      DOI: 10.1016/j.scr.2023.103188

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    sciencedirect.com/science/article/pii/S1873506123001745
  45. Jul 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Generation of vascularized human cardiac organoids for 3D in vitro modeling
    1
    1. scibot 05 Jul 2023
      RRID:AB_476766

      DOI: 10.1016/j.xpro.2023.102371

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    sciencedirect.com/science/article/pii/S2666166723003386
  47. Jun 2023
  48. www.sciencedirect.com www.sciencedirect.com
    High-throughput longitudinal electrophysiology screening of mature chamber-specific hiPSC-CMs using optical mapping
    1
    1. scibot 29 Jun 2023
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      DOI: 10.1016/j.isci.2023.107142

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    sciencedirect.com/science/article/pii/S2589004223012191
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Restored autophagy is protective against PAK3-induced cardiac dysfunction
    1
    1. scibot 17 Jun 2023
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      DOI: 10.1016/j.isci.2023.106970

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    ncbi.nlm.nih.gov/pmc/articles/PMC10265534/
  50. May 2023
  51. www.nature.com www.nature.com
    Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs
    1
    1. scibot 28 May 2023
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      DOI: 10.1038/s41536-023-00302-6

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    nature.com/articles/s41536-023-00302-6
  52. www.biorxiv.org www.biorxiv.org
    FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis
    1
    1. scibot 25 May 2023
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      DOI: 10.1101/2023.05.20.541585

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    biorxiv.org/content/10.1101/2023.05.20.541585v1
  53. www.sciencedirect.com www.sciencedirect.com
    Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V
    1
    1. scibot 03 May 2023
      RRID:AB_476766

      DOI: 10.1016/j.scr.2023.103108

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    sciencedirect.com/science/article/pii/S1873506123000946
  54. Apr 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Vascular cells improve functionality of human cardiac organoids
    1
    1. scibot 27 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112322

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    sciencedirect.com/science/article/pii/S2211124723003339
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    Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells
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    Multimodal charting of molecular and functional cell states via in situ electro-sequencing
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    Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
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  59. Mar 2023
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    Activation of β-catenin in mesenchymal progenitors leads to muscle mass loss
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  61. Nov 2022
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    Generation of human induced pluripotent stem cell line encoding for a genetically encoded voltage indicator Arclight A242
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    SENP7 deSUMOylase-governed transcriptional program coordinates sarcomere assembly and is targeted in muscle atrophy
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    Single cell sequencing maps skeletal muscle cellular diversity as disease severity increases in dystrophic mouse models
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    Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2
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  67. Oct 2022
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    Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities
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  69. Sep 2022
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    STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells
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  71. Aug 2022
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    Generation of self-assembling cardiac organoids using hiPSC-derived cardiomyocytes
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  73. 52.53.155.43 52.53.155.43
    Endogenous slow and fast myosin dynamics in myofibers isolated from mice expressing GFP-Myh7 and Kusabira Orange-Myh1
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      DOI: 10.1152/ajpcell.00415.2021

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  74. journals.physiology.org journals.physiology.org
    Endogenous slow and fast myosin dynamics in myofibers isolated from mice expressing GFP-Myh7 and Kusabira Orange-Myh1
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Septin7 is indispensable for proper skeletal muscle architecture and function
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  76. Jun 2022
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    The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load
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  78. May 2022
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    Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15
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  80. Apr 2022
  81. www.sciencedirect.com www.sciencedirect.com
    RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development
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    Generation of heterozygous (MRli003-A-5) and homozygous (MRli003-A-6) voltage-sensing knock-in human iPSC lines by CRISPR/Cas9 editing of the AAVS1 locus
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    Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons
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  84. Mar 2022
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    Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy
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    Engineering of thick human functional myocardium via static stretching and electrical stimulation
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    Generation of heterozygous (MRli003-A-3) and homozygous (MRli003-A-4) TRPM4 knockout human iPSC lines
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  88. Feb 2022
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    MBNL1 drives dynamic transitions between fibroblasts and myofibroblasts in cardiac wound healing
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    Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability
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    Generation of human induced pluripotent stem cell lines encoding for genetically encoded calcium indicators RCaMP1h and GCaMP6f
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  92. Jan 2022
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    Generation of SCN5A heterozygous knock-out human induced pluripotent stem cell line by CRISPR/Cas9-mediated genome editing
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  94. Dec 2021
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    Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome
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    Generation of a human induced pluripotent stem cell line YCMi004-A from a patient with dilated cardiomyopathy carrying a protein-truncating mutation of the Titin gene and its differentiation towards cardiomyocytes
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  97. Nov 2021
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    Generation of heterozygous (MRli003-A-1) and homozygous (MRli003-A-2) MYH10 knockout human iPSC lines
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    Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual
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    Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction
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    Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload
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  102. Oct 2021
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MACF1 controls skeletal muscle function through the microtubule-dependent localization of extra-synaptic myonuclei and mitochondria biogenesis
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  104. Sep 2021
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    Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species
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    RARG variant predictive of doxorubicin-induced cardiotoxicity identifies a cardioprotective therapy
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  107. Aug 2021
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    Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2
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    Generation of the human induced pluripotent stem cell (hiPSC) line PSMi006-A from a patient affected by an autosomal recessive form of Long QT Syndrome type 1
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  110. Jul 2021
  111. www.sciencedirect.com www.sciencedirect.com
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  112. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      mouse anti‐α‐actinin

      DOI: 10.1111/bph.14795

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14795
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
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      DOI: 10.1016/j.stem.2019.01.013

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  114. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation
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      DOI: 10.1016/j.stem.2018.09.009

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  115. www.sciencedirect.com www.sciencedirect.com
    Generation of a NKX2.1 – p63 double transgenic knock-in reporter cell line from human induced pluripotent stem cells (MHHi006-A-4)
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      DOI: 10.1016/j.scr.2019.101659

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  116. May 2021
  117. www.sciencedirect.com www.sciencedirect.com
    Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes
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      DOI: 10.1016/j.celrep.2021.109100

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    sciencedirect.com/science/article/pii/S2211124721004344
  118. www.sciencedirect.com www.sciencedirect.com
    Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes
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      DOI: 10.1016/j.stem.2020.06.001

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  119. www.sciencedirect.com www.sciencedirect.com
    Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome
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      DOI: 10.1016/j.stem.2020.07.015

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    Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion
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      DOI: 10.1016/j.devcel.2021.01.016

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  121. www.sciencedirect.com www.sciencedirect.com
    Prestin amplifies cardiac motor functions
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      DOI: 10.1016/j.celrep.2021.109097

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  122. www.sciencedirect.com www.sciencedirect.com
    Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment
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      DOI: 10.1016/j.celrep.2021.109088

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  123. Apr 2021
  124. www.nature.com www.nature.com
    A well plate–based multiplexed platform for incorporation of organoids into an organ-on-a-chip system with a perfusable vasculature
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      DOI: 10.1038/s41596-020-00490-1

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  125. Mar 2021
  126. www.nature.com www.nature.com
    Generation, functional analysis and applications of isogenic three-dimensional self-aggregating cardiac microtissues from human pluripotent stem cells
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      DOI: 10.1038/s41596-021-00497-2

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  127. link.springer.com link.springer.com
    Isolated downregulation of HCN2 in ventricles of rats with streptozotocin-induced diabetic cardiomyopathy
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      DOI: 10.1186/s12872-021-01929-3

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  128. Feb 2021
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human iPSC-Derived Cardiomyocytes , are Susceptible to SARS-CoV-2 Infection
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      RRID:AB_476766

      DOI: 10.1016/j.xcrm.2020.100052

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  130. www.sciencedirect.com www.sciencedirect.com
    Generation and cardiac differentiation of an induced pluripotent stem cell line from a patient with arrhythmia-induced cardiomyopathy
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      RRID:AB_476766

      DOI: 10.1016/j.scr.2021.102263

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  131. www.sciencedirect.com www.sciencedirect.com
    Generation of the human induced pluripotent stem cell (hiPSC) line PSMi006-A from a patient affected by an autosomal recessive form of Long QT Syndrome type 1
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      RRID:AB_476

      DOI: 10.1016/j.scr.2019.101658

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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Protein Kinase C Modulators Reveal a Pro-hypertrophic Role for Novel Protein Kinase C Isoforms in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
    1
    1. scibot 12 Feb 2021
      RRID:AB_476766

      DOI: 10.3389/fphar.2020.553852

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  133. www.sciencedirect.com www.sciencedirect.com
    Establishment of MHHi001-A-5, a GCaMP6f and RedStar dual reporter human iPSC line for in vitro and in vivo characterization and in situ-tracing of iPSC-derivatives
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    1. scibot 03 Feb 2021
      RRID:AB_476766

      DOI: 10.1016/j.scr.2021.102206

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  134. Jan 2021
  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Graded titin cleavage progressively reduces tension and uncovers the source of A-band stability in contracting muscle
    1
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      RRID:AB_476766

      DOI: 10.7554/eLife.64107

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    ncbi.nlm.nih.gov/pmc/articles/PMC7781594/
  136. Dec 2020
  137. www.sciencedirect.com www.sciencedirect.com
    Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing
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      RRID:AB_476766

      DOI: 10.1016/j.scr.2020.102135

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    sciencedirect.com/science/article/pii/S1873506120304360
  138. www.sciencedirect.com www.sciencedirect.com
    Generation of a Human iPSC Line GIBHi002-A-2 with Dual-Reporter for NKX2-5 Using TALENs
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      RRID:AB_476766

      DOI: 10.1016/j.scr.2020.102120

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    sciencedirect.com/science/article/pii/S1873506120304219
  139. Sep 2020
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Variable expression and silencing of CRISPR-Cas9 targeted transgenes identifies the AAVS1 locus as not an entirely safe harbour
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      RRID:AB_476766

      DOI: 10.12688/f1000research.19894.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC7401084/
  141. www.sciencedirect.com www.sciencedirect.com
    Myosin-18B Regulates Higher-Order Organization of the Cardiac Sarcomere through Thin Filament Cross-Linking and Thick Filament Dynamics
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      RRID:AB_476766

      DOI: 10.1016/j.celrep.2020.108090

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    sciencedirect.com/science/article/pii/S2211124720310792
  142. www.sciencedirect.com www.sciencedirect.com
    Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration
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      RRID:AB_476766

      DOI: 10.1016/j.devcel.2020.01.030

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  143. www.sciencedirect.com www.sciencedirect.com
    Direct Comparison of Mononucleated and Binucleated Cardiomyocytes Reveals Molecular Mechanisms Underlying Distinct Proliferative Competencies
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      DOI: 10.1016/j.celrep.2020.02.034

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  144. www.sciencedirect.com www.sciencedirect.com
    Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease
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      DOI: 10.1016/j.stem.2020.05.004

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    sciencedirect.com/science/article/pii/S1934590920302022
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    Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes
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      DOI: 10.1016/j.celrep.2020.107925

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    Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress
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      DOI: 10.1016/j.celrep.2020.108087

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  147. www.sciencedirect.com www.sciencedirect.com
    Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes
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      DOI: 10.1016/j.xpro.2020.100026

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    sciencedirect.com/science/article/pii/S2666166720300137
  148. www.sciencedirect.com www.sciencedirect.com
    Human STAT1 gain-of-function iPSC line from a patient suffering from chronic mucocutaneous candidiasis
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  149. www.sciencedirect.com www.sciencedirect.com
    Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation
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      DOI: 10.1016/j.scr.2020.101944

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  150. www.sciencedirect.com www.sciencedirect.com
    An Optimized Protocol for Human Direct Cardiac Reprogramming
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  151. f1000research.com f1000research.com
    F1000Research Article: Variable expression and silencing of CRISPR-Cas9 targeted transgenes identifies the <i>AAVS1</i> locus as not an entirely safe harbour.
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      RRID:AB_476766

      DOI: 10.12688/f1000research.19894.2

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  152. www.sciencedirect.com www.sciencedirect.com
    Generation of pluripotent stem cell lines and CRISPR/Cas9 modified isogenic controls from a patient with dilated cardiomyopathy harboring a RBM20 p.R634W mutation
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      RRID:AB_476766

      DOI: 10.1016/j.scr.2020.101901

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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors
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      DOI: 10.7554/eLife.46981

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  154. Jan 2020
  155. www.sciencedirect.com www.sciencedirect.com
    Rational Reprogramming of Cellular States by Combinatorial Perturbation
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      DOI: 10.1016/j.celrep.2019.05.079

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  156. www.sciencedirect.com www.sciencedirect.com
    Conversion of Astrocytes and Fibroblasts into Functional Noradrenergic Neurons
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      DOI: 10.1016/j.celrep.2019.06.042

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  157. www.sciencedirect.com www.sciencedirect.com
    Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells
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      DOI: 10.1016/j.celrep.2019.11.047

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    sciencedirect.com/science/article/pii/S2211124719315293
  158. www.sciencedirect.com www.sciencedirect.com
    Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNFS621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming
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    1. scibot 13 Jan 2020
      RRID:AB_476766

      DOI: 10.1016/j.scr.2019.101530

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    Mechanical Forces Regulate Cardiomyocyte Myofilament Maturation via the VCL-SSH1-CFL Axis
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      DOI: 10.1016/j.devcel.2019.08.006

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    Generation of the human induced pluripotent stem cell (hiPSC) line PSMi006-A from a patient affected by an autosomal recessive form of Long QT Syndrome type 1
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      RRID:AB_476766

      DOI: 10.1016/j.scr.2019.101658

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  161. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.scr.2019.101416

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      DOI: 10.1016/j.scr.2019.101437

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  163. www.sciencedirect.com www.sciencedirect.com
    In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors
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      RRID:AB_476766

      DOI: 10.1016/j.celrep.2019.02.083

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    Regulation of SETD7 Methyltransferase by SENP3 Is Crucial for Sarcomere Organization and Cachexia
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      DOI: 10.1016/j.celrep.2019.04.107

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    Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway
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      DOI: 10.1016/j.stem.2019.03.009

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      DOI: 10.1016/j.celrep.2019.01.060

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    Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming
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      DOI: 10.1016/j.celrep.2019.04.077

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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.7554/eLife.40532

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      DOI: 10.1016/j.scr.2019.101431

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      DOI: 10.1016/j.stem.2019.01.013

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  172. Nov 2018
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  174. elifesciences.org elifesciences.org
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    Tbx6 Induces Nascent Mesoderm from Pluripotent Stem Cells and Temporally Controls Cardiac versus Somite Lineage Diversification
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    Generation of the human induced pluripotent stem cell (hiPSC) line PSMi003-A from a patient affected by an autosomal recessive form of Long QT Syndrome type 1
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      RRID:AB_476766

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  177. www.sciencedirect.com www.sciencedirect.com
    Generation of the human induced pluripotent stem cell (hiPSC) line PSMi002-A from a patient affected by the Jervell and Lange-Nielsen syndrome and carrier of two compound heterozygous mutations on the KCNQ1 gene
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions
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    Direct In Vivo Reprogramming with Sendai Virus Vectors Improves Cardiac Function after Myocardial Infarction
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  181. Nov 2017
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    Quaking RNA-Binding Proteins Control Early Myofibril Formation by Modulating Tropomyosin
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      RRID:AB_476766

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    sciencedirect.com/science/article/pii/S1534580717306329
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      AB_476766

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    Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription downstream of endothelin type A receptors
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      AB_476766

      Curator: @gabimpine

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    Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization
    1
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      α-actinin2 (Sigma clone A7811, 1:100)

      Curator: @chewbeccax

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