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Competition for microtubule lattice spacing between a microtubule expander and compactor

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1. scibot 30 Aug 2025
  
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  DOI: 10.1016/j.cub.2025.07.080
  
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sciencedirect.com/science/article/pii/S0960982225010255
Jul 2025
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Macrophage fatty acid metabolism under chronic hypoxia shapes γδ T cell recruitment via CCL22.

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113025
  
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sciencedirect.com/science/article/pii/S2589004225012866
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Modulation of glucocorticoid receptor function under iron overload

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1. scibot 04 Jul 2025
  
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  DOI: 10.3389/fimmu.2025.1605420
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12213461/
Apr 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225005346-main-html.html

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.isci.2025.112273
  
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52.53.155.43/ffc1abcd89845af00863627f973ae3032304893a/1-s2.0-S2589004225005346-main-html.html
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The Chlamydia effector Dre1 binds dynactin to reposition host organelles during infection

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115509
  
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sciencedirect.com/science/article/pii/S2211124725002803
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115401
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12035956/
Dec 2024
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Phosphorylation of Optineurin by protein kinase D regulates Parkin-dependent mitophagy

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1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111384
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11634986/
Aug 2024
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Optogenetic control of kinesin-1, -2, -3 and dynein reveals their specific roles in vesicular transport

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114649
  
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sciencedirect.com/science/article/pii/S2211124724010003
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Protective upregulation of activating transcription factor‐3 against glutamate neurotoxicity in neuronal cells under ischemia

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1. scibot 02 Aug 2024
  
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  DOI: 10.1002/jnr.23723
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.23723/full
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Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex

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1. scibot 02 Aug 2024
  
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  DOI: 10.1002/cne.23691
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23691/full
Jul 2024
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Innate immune memory after brain injury drives inflammatory cardiac dysfunction

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.06.028
  
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sciencedirect.com/science/article/pii/S0092867424007025
52.53.155.43 52.53.155.43

A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies

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1. scibot 23 Jul 2024
  
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  DOI: 10.1111/jnc.14295
  
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52.53.155.43/0bf5a35474616f8cd124d354ba59ef8784f885ac/A_dual_role_for_Integrin_64_in_modulat-html.html
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Spatiotemporal sphingosine-1-phosphate receptor 3 expression within the cerebral vasculature after ischemic stroke

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1. scibot 14 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110031
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11167442/
Apr 2024
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The chromatin remodeler CHD4 sustains Ewing Sarcoma cell survival by controlling global chromatin architecture

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1. scibot 19 Apr 2024
  
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  DOI: 10.1158/0008-5472.CAN-22-3950
  
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aacrjournals.org/cancerres/article/84/2/241/733111/The-Chromatin-Remodeler-CHD4-Sustains-Ewing
Mar 2024
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RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis

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1. scibot 27 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109400
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10959657/
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Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons

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1. scibot 23 Mar 2024
  
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  DOI: 10.7554/eLife.92342
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10957175/
www.biorxiv.org www.biorxiv.org

Prostaglandin D2 synthase controls Schwann cells metabolism

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1. scibot 21 Mar 2024
  
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  DOI: 10.1101/2024.02.29.582775
  
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biorxiv.org/content/10.1101/2024.02.29.582775v1
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A Highlights from MBoC Selection: Preexisting tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia

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1. scibot 02 Mar 2024
  
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  RRID:AB_477577
  
  DOI: 10.1091/mbc.E23-08-0337
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10881161/
Feb 2024
52.53.155.43 52.53.155.43

241-html.html

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1. scibot 23 Feb 2024
  
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  DOI: 10.1158/0008-5472.can-22-3950
  
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52.53.155.43/ef1c2343cba3a29438101d6931686796493196a8/241-html.html
Jan 2024
www.mdpi.com www.mdpi.com

BAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation

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1. scibot 07 Jan 2024
  
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  DOI: 10.3390/ijms25010453
  
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mdpi.com/1422-0067/25/1/453
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Akt activation ameliorates deficits in hippocampal-dependent memory and activity-dependent synaptic protein synthesis in an Alzheimer’s disease mouse model

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1. scibot 06 Jan 2024
  
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  DOI: 10.1016/j.jbc.2023.105619
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10839450/
Nov 2023
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MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice

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1. scibot 03 Nov 2023
  
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  DOI: 10.1186/s40478-023-01654-2
  
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link.springer.com/article/10.1186/s40478-023-01654-2
Oct 2023
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MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.devcel.2023.09.010
  
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sciencedirect.com/science/article/pii/S1534580723005129
Sep 2023
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Silc1 long noncoding RNA is an immediate-early gene promoting efficient memory formation

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113168
  
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sciencedirect.com/science/article/pii/S2211124723011804
Aug 2023
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Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia

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1. scibot 30 Aug 2023
  
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  DOI: 10.1016/j.devcel.2023.08.009
  
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sciencedirect.com/science/article/abs/pii/S1534580723004057
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Luteal Lipid Droplets: A Novel Platform for Steroid Synthesis

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1. scibot 24 Aug 2023
  
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  DOI: 10.1210/endocr/bqad124
  
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dx.doi.org/10.1210/endocr/bqad124
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cellular heterogeneity in the 16HBE14o − airway epithelial line impacts biological readouts

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1. scibot 07 Jun 2023
  
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  DOI: 10.14814/phy2.15700
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10238858/
www.jneurosci.org www.jneurosci.org

A unique role for Protocadherin γC3 in promoting dendrite arborization through an Axin1-dependent mechanism

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1. scibot 01 Jun 2023
  
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  DOI: 10.1523/JNEUROSCI.0729-22.2022
  
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jneurosci.org/content/43/6/918
May 2023
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EWSR1 maintains centromere identity

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1. scibot 27 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112568
  
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sciencedirect.com/science/article/pii/S221112472300579X
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Methylated histones on mitotic chromosomes promote Topoisomerase IIα function for high fidelity chromosome segregation.

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1. scibot 14 May 2023
  
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  DOI: 10.1016/j.isci.2023.106743
  
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sciencedirect.com/science/article/pii/S2589004223008209
Apr 2023
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Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex

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1. scibot 26 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106563
  
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sciencedirect.com/science/article/pii/S2589004223006405
www.nature.com www.nature.com

Sex difference in evolution of cognitive decline: studies on mouse model and the Dominantly Inherited Alzheimer Network cohort

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1. scibot 18 Apr 2023
  
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  DOI: 10.1038/s41398-023-02411-8
  
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nature.com/articles/s41398-023-02411-8
www.cell.com www.cell.com

Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation

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1. scibot 12 Apr 2023
  
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  DOI: 10.1016/j.ccell.2023.03.008
  
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cell.com/cancer-cell/abstract/S1535-6108(23)00081-8
Mar 2023
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Therapeutic potency of compound RMY-205 for pulmonary fibrosis induced by SARS-CoV-2 nucleocapsid protein

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1. scibot 11 Mar 2023
  
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  DOI: 10.1016/j.chembiol.2023.02.004
  
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sciencedirect.com/science/article/pii/S2451945623000533
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COP I and II dependent trafficking controls ER-associated degradation in mammalian cells

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1. scibot 03 Mar 2023
  
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  DOI: 10.1016/j.isci.2023.106232
  
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sciencedirect.com/science/article/pii/S2589004223003097
Feb 2023
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3D human induced pluripotent stem cell–derived bioengineered skeletal muscles for tissue, disease and therapy modeling

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F1000Research Article: Tumour cell suppression by spiroleucettadine through dual regulation of cell cycle and apoptosis.

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The FDA-approved drug Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-κB signaling

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A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation

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XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation

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Septin 9 and phosphoinositides regulate lysosome localization and their association with lipid droplets

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MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

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Molecular mechanisms of synaptic vesicle priming by Munc13 and Munc18

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Glutamine-dependent signaling controls pluripotent stem cell fate

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Molecular and functional architecture of striatal dopamine release sites

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SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase

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Role of EphrinA3 in HIV-1 Neuropathogenesis

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Neuroblastoma differentiation in vivo excludes cranial tumors

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Distinct classes of lagging chromosome underpin age-related oocyte aneuploidy in mouse

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Separase cleaves the kinetochore protein Meikin at the meiosis I/II transition

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Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer

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Novel Function of a Transcription Factor WT1 in Regulating Decidualization in Human Endometrial Stromal Cells and Its Molecular Mechanism

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Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer

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Combined inhibition of the PI3K/mTOR/MEK pathway induces Bim/Mcl-1-regulated apoptosis in pancreatic cancer cells

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Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling

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Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis

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Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis

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Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition

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R7 photoreceptor axon targeting depends on the relative levels of lost and found expression in R7 and its synaptic partners

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Decoding Human Megakaryocyte Development

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Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment

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Caveolae Control Contractile Tension for Epithelia to Eliminate Tumor Cells

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PTEN dephosphorylates Abi1 to promote epithelial morphogenesis

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Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51

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Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion

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Diverse viral proteases activate the NLRP1 inflammasome

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Correlating STED and synchrotron XRF nano-imaging unveils cosegregation of metals and cytoskeleton proteins in dendrites

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An AMPK-dependent, non-canonical p53 pathway plays a key role in adipocyte metabolic reprogramming

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De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment

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An integrated genomic approach identifies HOXC8 as an upstream regulator in ovarian endometrioma

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Phosphorylation of eIF2α promotes Schwann cell differentiation and myelination in CMT1B mice with activated UPR

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Dopamine promotes the neurodegenerative potential of β‐synuclein

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Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice

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Intramembrane proteolysis of an extracellular serine protease, epithin/PRSS14, enables its intracellular nuclear function

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NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation

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Tropomyosin Receptor Kinase B Expressed in Oligodendrocyte Lineage Cells Functions to Promote Myelin Following a Demyelinating Lesion - Yangyang Huang, Yeri J. Song, Maria Isaac, Shir Miretzky, Ashish Patel, W. Geoffrey McAuliffe, Cheryl F. Dreyfus, 2020

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PDGF-B Is Required for Development of the Glymphatic System

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A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers

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Early Neurotoxic Effects of Inorganic Arsenic Modulate Cortical GSH Levels Associated With the Activation of the Nrf2 and NFκB Pathways, Expression of Amino Acid Transporters and NMDA Receptors and the Production of Hydrogen Sulfide

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OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis

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DIX Domain Polymerization Drives Assembly of Plant Cell Polarity Complexes

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Gallic acid attenuates blood-spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury

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Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans

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PTEN suppresses epithelial–mesenchymal transition and cancer stem cell activity by downregulating Abi1

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The LMTK1—TBC1D9B—Rab11A cascade regulates dendritic spine formation via endosome trafficking

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Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR Inhibition

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The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells

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Direct Gαq Gating Is the Sole Mechanism for TRPM8 Inhibition Caused by Bradykinin Receptor Activation

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Neuronal Trans-differentiation by Transcription Factors Ascl1 and Nurr1: Induction of a Dopaminergic Neurotransmitter Phenotype in Cortical GABAergic Neurons

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The transcriptional repressor SNAI2 impairs neuroblastoma differentiation and inhibits response to retinoic acid therapy

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Induced pluripotent stem cells (iPSCs) derived from a Renpenning Syndrome Patient with c.459_462delAGAG Mutation in PQBP1 (PEIi001-A)

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Untitled document

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Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain

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Combined inhibition of the PI3K/mTOR/MEK pathway induces Bim/Mcl-2-regulated apoptosis in pancreatic cancer cells

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Sustained Expression of Negative Regulators of Myelination Protects Schwann Cells from Dysmyelination in a Charcot–Marie–Tooth 1B Mouse Model

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Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown

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Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53

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Importin-β Directly Regulates the Motor Activity and Turnover of a Kinesin-4

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Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma

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A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

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Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation

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A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies

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The cystine‐glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain

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Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18

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Food Intake Affects Sperm-Egg Fusion Through the GIP/PSG17 Axis in Mice

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Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5

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Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma

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Protective upregulation of activating transcription factor‐3 against glutamate neurotoxicity in neuronal cells under ischemia

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Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons

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Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex

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Cell adhesion molecule contactin‐associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages

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