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  1. Nov 2024
  2. journals.plos.org journals.plos.org
    Rho1 and Rgf1 establish a new actin-dependent signal to determine growth poles in yeast independently of microtubules and the Tea1–Tea4 complex
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    1. scibot 14 Nov 2024
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      DOI: 10.1371/journal.pbio.3002491

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    journals.plos.org/plosbiology/article
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-cell-autonomous regulation of germline proteostasis by insulin/IGF-1 signaling-induced dietary peptide uptake via PEPT-1
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    1. scibot 08 Nov 2024
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      DOI: 10.1038/s44318-024-00234-x

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    pmc.ncbi.nlm.nih.gov/articles/PMC11535032/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV2 Nsp3 protein triggers cell death and exacerbates amyloid β42-mediated neurodegeneration
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    1. scibot 07 Nov 2024
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      DOI: 10.4103/1673-5374.382989

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    ncbi.nlm.nih.gov/pmc/articles/PMC11467943/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The 419th Aspartic Acid of Neural Membrane Protein Enolase 2 Is a Key Residue Involved in the Axonal Growth of Motor Neurons Mediated by Interaction between Enolase 2 Receptor and Extracellular Pgk1 Ligand
    1
    1. scibot 07 Nov 2024
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      DOI: 10.3390/ijms251910753

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    pmc.ncbi.nlm.nih.gov/articles/PMC11477227/
  6. Oct 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peptidoglycan-Chi3l1 interaction shapes gut microbiota in intestinal mucus layer
    1
    1. scibot 09 Oct 2024
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      DOI: 10.7554/eLife.92994

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    ncbi.nlm.nih.gov/pmc/articles/PMC11458176/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1
    1
    1. scibot 08 Oct 2024
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      DOI: 10.1083/jcb.202311189

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    ncbi.nlm.nih.gov/pmc/articles/PMC11451052/
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    Arf1-dependent LRBA recruitment to Rab4 endosomes is required for endolysosome homeostasis
    1
    1. scibot 05 Oct 2024
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      DOI: 10.1083/jcb.202401167

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    ncbi.nlm.nih.gov/pmc/articles/PMC11449124/
  10. www.sciencedirect.com www.sciencedirect.com
    Midkine as a driver of age-related changes and increase in mammary tumorigenesis
    1
    1. scibot 04 Oct 2024
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    sciencedirect.com/science/article/pii/S1535610824003507
  11. Sep 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Geranylgeranylated SCFFBXO10 regulates selective outer mitochondrial membrane proteostasis and function
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114783

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    sciencedirect.com/science/article/pii/S2211124724011343
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    Lysosome-related organelle integrity suppresses TIR-1 aggregation to restrain toxic propagation of p38 innate immunity
    1
    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724010258
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    Intestinal immunity in C. elegans is activated by pathogen effector-triggered aggregation of the guard protein TIR-1 on lysosome-related organelles
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.immuni.2024.08.013

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    sciencedirect.com/science/article/pii/S1074761324004126
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes
    1
    1. scibot 05 Sep 2024
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      DOI: 10.1038/s41467-024-51676-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11362472/
  16. Aug 2024
  17. www.sciencedirect.com www.sciencedirect.com
    MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation
    1
    1. scibot 29 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114682

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    sciencedirect.com/science/article/pii/S2211124724010337
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    The cell cycle controls spindle architecture in Arabidopsis by activating the augmin pathway
    1
    1. scibot 27 Aug 2024
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      DOI: 10.1016/j.devcel.2024.08.001

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    sciencedirect.com/science/article/pii/S1534580724004842
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical function of ADAM10 in presynaptic plasticity
    1
    1. scibot 23 Aug 2024
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      DOI: 10.1007/s00018-024-05327-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC11335265/
  20. www.sciencedirect.com www.sciencedirect.com
    The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
    1
    1. scibot 19 Aug 2024
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    sciencedirect.com/science/article/pii/S2589004224017243
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    Fission yeast Bgs1 glucan synthase participates in the control of growth polarity and membrane traffic
    1
    1. scibot 14 Aug 2024
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      DOI: 10.1016/j.isci.2024.110477

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    sciencedirect.com/science/article/pii/S2589004224017024
  22. www.mdpi.com www.mdpi.com
    Histone Methyltransferase G9a-Promoted Progression of Hepatocellular Carcinoma Is Targeted by Liver-Specific Hsa-miR-122
    1
    1. scibot 02 Aug 2024
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      DOI: 10.3390/cancers13102376

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    mdpi.com/2072-6694/13/10/2376/htm
  23. Jul 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of the main barriers to Ku accumulation in chromatin
    1
    1. scibot 30 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11411529/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TP53INP2-dependent activation of muscle autophagy ameliorates sarcopenia and promotes healthy aging
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1080/15548627.2024.2333717

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    ncbi.nlm.nih.gov/pmc/articles/PMC11262205/
  26. www.sciencedirect.com www.sciencedirect.com
    TERT activation targets DNA methylation and multiple aging hallmarks
    1
    1. scibot 24 Jul 2024
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      DOI: 10.1016/j.cell.2024.05.048

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    sciencedirect.com/science/article/pii/S0092867424005920
  27. www.cell.com www.cell.com
    Reproductive regulation of the mitochondrial stress response in Caenorhabditis elegans
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114336

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    cell.com/cell-reports/abstract/S2211-1247(24)00664-8
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.celrep.2020.107695

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    ncbi.nlm.nih.gov/pmc/articles/PMC7262597/
  29. www.cell.com www.cell.com
    A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence
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    1. scibot 11 Jul 2024
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      DOI: 10.1016/j.cell.2024.06.019

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    cell.com/cell/fulltext/S0092-8674(24)00693-7
  30. www.sciencedirect.com www.sciencedirect.com
    Incense-burning smoke ingredient Auramine enhances lincRNA-p21 expression for chemosensitization in p53-mutated non-small cell lung cancer
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      DOI: 10.1016/j.jhazmat.2024.135105

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    sciencedirect.com/science/article/pii/S0304389424016844
  31. www.sciencedirect.com www.sciencedirect.com
    Dystrophin deficiency impairs cell junction formation during embryonic myogenesis from pluripotent stem cells
    1
    1. scibot 10 Jul 2024
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      DOI: 10.1016/j.isci.2024.110242

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    sciencedirect.com/science/article/pii/S2589004224014676
  32. www.sciencedirect.com www.sciencedirect.com
    Supernumerary proteins of the human mitochondrial ribosomal small subunit are integral for assembly and translation
    1
    1. scibot 10 Jul 2024
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      DOI: 10.1016/j.isci.2024.110185

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    sciencedirect.com/science/article/pii/S258900422401410X
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stochastic RNA editing of the Complexin C-terminus within single neurons regulates neurotransmitter release
    1
    1. scibot 08 Jul 2024
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      DOI: 10.1016/j.celrep.2023.113152

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    ncbi.nlm.nih.gov/pmc/articles/PMC10591831/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phosphorylation-controlled switch confers cell cycle-dependent protein relocalization
    1
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      DOI: 10.1101/2024.06.05.597552

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    ncbi.nlm.nih.gov/pmc/articles/PMC11185714/
  35. Jun 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetyl-NPKY of Integrin-beta 1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
    1
    1. scibot 30 Jun 2024
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      DOI: 10.1016/j.isci.2024.110129

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    ncbi.nlm.nih.gov/pmc/articles/PMC11187247/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiretroviral treatment reveals a novel role for lysosomes in oligodendrocyte maturation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10724866/
  38. May 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Upregulation of neuronal ER-phagy improves organismal fitness and alleviates APP toxicity
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    sciencedirect.com/science/article/pii/S2211124724005837
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    TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks
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    sciencedirect.com/science/article/pii/S2211124724005424
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    Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin
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    sciencedirect.com/science/article/pii/S0092867424004094
  42. 52.53.155.43 52.53.155.43
    Host-pathogen Coadaptation by running with PAR protein
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    52.53.155.43/ed26dad54fa8ad8f27865dcc79d9a69d83befd62/2024.01.31.578330v1.full-html.html
  43. 52.53.155.43 52.53.155.43
    SIRT1 mediates the antagonism of Wnt/β-catenin pathway by vitamin D in colon carcinoma cells
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  44. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
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    52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
  45. www.biorxiv.org www.biorxiv.org
    Rgf1 GEF activity toward Rho1 defines a new actin-dependent signal to determine growth sites independently of microtubules and Tea1
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      DOI: 10.1101/2024.01.10.574961

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    biorxiv.org/content/10.1101/2024.01.10.574961v1
  46. 52.53.155.43 52.53.155.43
    Mitochondrial clearance and increased HSF-1 activity are coupled to promote longevity in fasted Caenorhabditis elegans
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    52.53.155.43/c3b2b2336037431417a6d40cca0ac9967aeadc36/PIIS2589004224010563-html.html
  47. Apr 2024
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    Lysosomal dysfunction by inactivation of V-ATPase drives innate immune response in C. elegans
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    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
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    Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1
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    Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates
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    A receptor required for chitin perception facilitates arbuscular mycorrhizal associations and distinguishes root symbiosis from immunity
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    AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway
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    MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
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    The microglial innate immune protein PGLYRP1 mediates neuroinflammation and consequent behavioral changes
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    VPS13B is localized at the cis-trans Golgi complex interface and is a functional partner of FAM177A1
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    VPS13B is localized at the cis-trans Golgi complex interface and is a functional partner of FAM177A1
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    Blood flow patterns switch VEGFR2 activity through differential S-nitrosylation and S-oxidation
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    SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing
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    The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A
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    Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases
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    Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons
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    Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms
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    CdGAP is a talin-binding protein and a target of TGF-β signaling that promotes HER2-positive breast cancer growth and metastasis
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    DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer
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    Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
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    The circadian clock CRY1 regulates pluripotent stem cell identity and somatic cell reprogramming
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  134. May 2023
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    The integrated LIM-peptidase domain of the CSA1-CHS3/DAR4 paired immune receptor detects changes in DA1 peptidase inhibitors in Arabidopsis
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    A proinsulin-dependent interaction between ENPL-1 and ASNA-1 in neurons is required to maintain insulin secretion in C. elegans
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    Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases
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    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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    Site-1 protease inhibits mitochondrial respiration by controlling the TGF-β target gene Mss51
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  150. Mar 2023
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    Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy
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  156. Feb 2023
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    Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans
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  159. Jan 2023
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    Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles
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    Cav1.3 L-type Ca2+ channel-activated CaMKII/ERK2 pathway in the ventral tegmental area is required for cocaine conditioned place preference
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    Loss of MTCH-1 suppresses age-related proteostasis collapse through the inhibition of programmed cell death factors
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    Size-Based Effects of Anthropogenic Ultrafine Particles on Lysosomal TRPML1 Channel and Autophagy in Motoneuron-like Cells
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    V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans
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    Unbiased proteomic and forward genetic screens reveal that mechanosensitive ion channel MSL10 functions at ER-plasma membrane contact sites in Arabidopsis thaliana
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    Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress
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    The autophagy inducer SMER28 attenuates microtubule dynamics mediating neuroprotection
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    A Short Promoter Region Containing Conserved Regulatory Motifs Is Required for Steroidogenic Acute Regulatory Protein (Star) Gene Expression in the Mouse Testis
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    Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy
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    The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth
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    PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis
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    Ubiquitin profiling of lysophagy identifies actin stabilizer CNN2 as a target of VCP/p97 and uncovers a link to HSPB1
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    Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo
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    Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
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    A function for Ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission
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    Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis
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    Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy
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    In vitro experiments and kinetic models of Arabidopsis pollen hydration mechanics show that MSL8 is not a simple tension-gated osmoregulator
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    The epilepsy-associated protein PCDH19 undergoes NMDA receptor-dependent proteolytic cleavage and regulates the expression of immediate-early genes
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    Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock
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