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  2. 52.53.155.43 52.53.155.43
    Host-pathogen Coadaptation by running with PAR protein
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    1. scibot 10 May 2024
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    52.53.155.43/ed26dad54fa8ad8f27865dcc79d9a69d83befd62/2024.01.31.578330v1.full-html.html
  3. May 2024
  4. 52.53.155.43 52.53.155.43
    SIRT1 mediates the antagonism of Wnt/β-catenin pathway by vitamin D in colon carcinoma cells
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    1. scibot 04 May 2024
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  5. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
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    1. scibot 04 May 2024
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    Rgf1 GEF activity toward Rho1 defines a new actin-dependent signal to determine growth sites independently of microtubules and Tea1
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    1. scibot 03 May 2024
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    biorxiv.org/content/10.1101/2024.01.10.574961v1
  7. 52.53.155.43 52.53.155.43
    Mitochondrial clearance and increased HSF-1 activity are coupled to promote longevity in fasted Caenorhabditis elegans
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    1. scibot 02 May 2024
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  8. Apr 2024
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    Lysosomal dysfunction by inactivation of V-ATPase drives innate immune response in C. elegans
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    1. scibot 30 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004662
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    BMP7 promotes cardiomyocyte regeneration in zebrafish and adult mice
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    sciencedirect.com/science/article/pii/S221112472400490X
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dystrophin deficiency impairs cell junction formation during embryonic myogenesis
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    1. scibot 28 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10723310/
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    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
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    1. scibot 26 Apr 2024
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    sciencedirect.com/science/article/pii/S0092867424003131
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    TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation
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    1. scibot 18 Apr 2024
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      DOI: 10.1084/jem.20231236

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    ncbi.nlm.nih.gov/pmc/articles/PMC11010340/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Balbiani body of basal insects is potentially involved in multiplication and selective elimination of mitochondria
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    1. scibot 13 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11004008/
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    Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1
    1
    1. scibot 10 Apr 2024
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      DOI: 10.7554/eLife.96891

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    ncbi.nlm.nih.gov/pmc/articles/PMC11001299/
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    Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates
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    1. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724003929
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    A receptor required for chitin perception facilitates arbuscular mycorrhizal associations and distinguishes root symbiosis from immunity
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    sciencedirect.com/science/article/pii/S0960982224003129
  18. Mar 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
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    1. scibot 19 Mar 2024
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      DOI: 10.7554/eLife.87386

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942603/
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    Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH
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    sciencedirect.com/science/article/pii/S1097276524001722
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    AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway
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      DOI: 10.1016/j.bbadis.2024.167116

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    sciencedirect.com/science/article/pii/S0925443924001054
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    Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
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    1. scibot 07 Mar 2024
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    sciencedirect.com/science/article/pii/S2589004224004401
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    MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
    2
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109188

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      DOI: 10.1016/j.isci.2024.109188

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    sciencedirect.com/science/article/pii/S2589004224004097
  24. Feb 2024
  25. www.sciencedirect.com www.sciencedirect.com
    The microglial innate immune protein PGLYRP1 mediates neuroinflammation and consequent behavioral changes
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    1. scibot 29 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001414
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PCID2 dysregulates transcription and viral RNA processing to promote HIV-1 latency
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    1. scibot 28 Feb 2024
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      DOI: 10.1016/j.isci.2024.109152

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879814/
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    PKCμ promotes keratinocyte cell migration through Cx43 phosphorylation-mediated suppression of intercellular communication
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    1. scibot 23 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875573/
  28. www.biorxiv.org www.biorxiv.org
    VPS13B is localized at the cis-trans Golgi complex interface and is a functional partner of FAM177A1
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    1. scibot 15 Feb 2024
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      DOI: 10.1101/2023.12.18.572081

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    biorxiv.org/content/10.1101/2023.12.18.572081v1
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling
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      DOI: 10.1016/j.isci.2024.108943

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    ncbi.nlm.nih.gov/pmc/articles/PMC10850750/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of ERBB receptors and downstream pathways reveals selectivity and hidden properties of ERBB4 antagonists
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      DOI: 10.1016/j.isci.2024.108839

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    ncbi.nlm.nih.gov/pmc/articles/PMC10831936/
  31. Jan 2024
  32. www.biorxiv.org www.biorxiv.org
    VPS13B is localized at the cis-trans Golgi complex interface and is a functional partner of FAM177A1
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    1. scibot 20 Jan 2024
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      DOI: 10.1101/2023.12.18.572081

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    biorxiv.org/content/10.1101/2023.12.18.572081v1
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    Live-cell imaging defines a threshold in CDK activity at the G2/M transition
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      DOI: 10.1016/j.devcel.2023.12.014

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    sciencedirect.com/science/article/pii/S1534580723006950
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    Live-cell imaging of endogenous CSB-mScarletI as a sensitive marker for DNA-damage-induced transcription stress
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      DOI: 10.1016/j.crmeth.2023.100674

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    sciencedirect.com/science/article/pii/S2667237523003533
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TDP-43 chronic deficiency leads to dysregulation of transposable elements and gene expression by affecting R-loop and 5hmC crosstalk
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      DOI: 10.1016/j.celrep.2023.113662

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    ncbi.nlm.nih.gov/pmc/articles/PMC10857847/
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    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
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    sciencedirect.com/science/article/pii/S2211124723016376
  37. Dec 2023
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
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      DOI: 10.3389/fnmol.2023.1323431

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    ncbi.nlm.nih.gov/pmc/articles/PMC10749327/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery
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      DOI: 10.1038/s41467-023-43614-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10730884/
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    Cell stretching activates an ATM mechano-transduction pathway that remodels cytoskeleton and chromatin
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    sciencedirect.com/science/article/pii/S221112472301567X
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer
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      DOI: 10.1371/journal.pgen.1011043

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    ncbi.nlm.nih.gov/pmc/articles/PMC10715669/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Highlights from MBoC Selection: Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins
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      DOI: 10.1091/mbc.E23-06-0233

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    ncbi.nlm.nih.gov/pmc/articles/PMC10559312/
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    Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms
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      DOI: 10.1016/j.xcrm.2023.101245

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    sciencedirect.com/science/article/pii/S2666379123004226
  44. Nov 2023
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis
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      DOI: 10.1038/s41467-023-43175-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10673935/
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    The hypoxia-inducible factor EPAS1 is required for spermatogonial stem cell function in regenerative conditions
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    SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing
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    The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A
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    Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases
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    CdGAP is a talin-binding protein and a target of TGF-β signaling that promotes HER2-positive breast cancer growth and metastasis
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    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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    An increased demand of FAD synthesis in Differentiated and Stem Pancreatic Cancer Cells is accomplished by modulating FLAD1 gene expression
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    DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer
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    Alternative splicing of GSDMB modulates killer lymphocyte–triggered pyroptosis
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    Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
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    The circadian clock CRY1 regulates pluripotent stem cell identity and somatic cell reprogramming
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    The integrated LIM-peptidase domain of the CSA1-CHS3/DAR4 paired immune receptor detects changes in DA1 peptidase inhibitors in Arabidopsis
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    Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
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    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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    Site-1 protease inhibits mitochondrial respiration by controlling the TGF-β target gene Mss51
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    Non-Oncogene Addiction of KRAS-Mutant Cancers to IL-1β via Versican and Mononuclear IKKβ
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    Loss of the Volume-regulated Anion Channel Components LRRC8A and LRRC8D Limits Platinum Drug Efficacy
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    Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans
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    Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles
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    Cav1.3 L-type Ca2+ channel-activated CaMKII/ERK2 pathway in the ventral tegmental area is required for cocaine conditioned place preference
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    V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans
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    Unbiased proteomic and forward genetic screens reveal that mechanosensitive ion channel MSL10 functions at ER-plasma membrane contact sites in Arabidopsis thaliana
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    Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy
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    The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth
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    Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo
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    In vitro experiments and kinetic models of Arabidopsis pollen hydration mechanics show that MSL8 is not a simple tension-gated osmoregulator
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    The epilepsy-associated protein PCDH19 undergoes NMDA receptor-dependent proteolytic cleavage and regulates the expression of immediate-early genes
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    Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock
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    Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals
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    FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer
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  186. Mar 2022
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    Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking
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    Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases
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    Self-incompatibility requires GPI anchor remodeling by the poppy PGAP1 ortholog HLD1
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    Loss of circadian rhythmicity in bdnf knockout zebrafish larvae
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    Cdc48 influence on separase levels is independent of mitosis and suggests translational sensitivity of separase
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    EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion
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    F-box protein FBXO41 plays vital role in arsenic trioxide-mediated autophagic death of cancer cells
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    The anti-diabetic drug metformin regulates voltage-gated sodium channel NaV1.7 via the ubiquitin-ligase NEDD4-2
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    Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma
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    An Inducible CRISPR/Cas9 Screen Identifies DTX2 as a Transcriptional Regulator of Human Telomerase
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    Pigment Epithelium Derived Factor Is Involved in the Late Phase of Osteosarcoma Metastasis by Increasing Extravasation and Cell-Cell Adhesion
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    ROPGAP-dependent interaction between brassinosteroid and ROP2-GTPase signaling controls pavement cell shape in Arabidopsis
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    SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage
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  206. Jan 2022
  207. diabetesjournals.org diabetesjournals.org
    Syntaxin 4 enrichment in β-cells prevents conversion to autoimmune diabetes in non-obese diabetic (NOD) mice
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    Purification of functional Plasmodium falciparum tubulin allows for the identification of parasite-specific microtubule inhibitors
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    Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
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  214. Dec 2021
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    Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
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    Circular RNA ZNF609/CKAP5 mRNA interaction regulates microtubule dynamics and tumorigenicity
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    Mitochondrial complex I inhibitors suppress tumor growth through concomitant acidification of the intra- and extracellular environment
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    Regulation of Na/K-ATPase expression by cholesterol: isoform specificity and the molecular mechanism
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  220. Nov 2021
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    Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation
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    Interplay between protein acetylation and ubiquitination controls MCL1 protein stability
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    A role for SMARCB1 in synovial sarcomagenesis reveals that SS18-SSX induces canonical BAF destruction
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    Stress-dependent inhibition of polarized cell growth through unbalancing the GEF/GAP regulation of Cdc42
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  226. Oct 2021
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    Faim knockout leads to gliosis and late-onset neurodegeneration of photoreceptors in the mouse retina
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      DOI: 10.1002/jnr.24978

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