164 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11574021/
  3. Nov 2024
  4. 52.53.155.43 52.53.155.43
    can-24-0529-html.html
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  5. Sep 2024
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    CDK5RAP2 activates microtubule nucleator γTuRC by facilitating template formation and actin release
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    sciencedirect.com/science/article/pii/S153458072400529X
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    Lamin chromatin binding is modulated by interactions of different LAP2α domains with lamins and chromatin
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    sciencedirect.com/science/article/pii/S2589004224020947
  8. Aug 2024
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    An actomyosin network organizes niche morphology and responds to feedback from recruited stem cells
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    sciencedirect.com/science/article/pii/S0960982224009448
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    Spindle assembly checkpoint-dependent mitotic delay is required for cell division in absence of centrosomes
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      DOI: 10.7554/eLife.84875

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    ncbi.nlm.nih.gov/pmc/articles/PMC11296703/
  11. www.cell.com www.cell.com
    GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy
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    cell.com/action/showExperimentalProcedures
  12. Jul 2024
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    The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells
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    sciencedirect.com/science/article/pii/S1534580724003794
  14. www.cell.com www.cell.com
    Wg/Wnt-signaling-induced nuclear translocation of β-catenin is attenuated by a β-catenin peptide through its interference with the IFT-A complex
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    cell.com/cell-reports/abstract/S2211-1247(24)00690-9
  15. Jun 2024
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    TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons
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    sciencedirect.com/science/article/pii/S0092867424005750
  17. May 2024
  18. 52.53.155.43 52.53.155.43
    Centriolar satellites are sites of translation of centrosomal and ciliary proteins
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    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
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  20. elifesciences.org elifesciences.org
    Spindle assembly checkpoint-dependent mitotic delay is required for cell division in absence of centrosomes
    1
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  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of tumor suppressor TMEM127 drives RET-mediated transformation through disrupted membrane dynamics
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      DOI: 10.7554/eLife.89100

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    ncbi.nlm.nih.gov/pmc/articles/PMC11060712/
  22. Apr 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response
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    ncbi.nlm.nih.gov/pmc/articles/PMC11052917/
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    Necrosulfonamide causes oxidation of PCM1 and impairs ciliogenesis and autophagy
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    Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery
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    sciencedirect.com/science/article/pii/S0960982224003075
  26. Mar 2024
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dysregulated lysosomal exocytosis drives protease-mediated cartilage pathogenesis in multiple lysosomal disorders
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    pmc.ncbi.nlm.nih.gov/articles/PMC10940929/
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    In vivo CRISPR screening directly targeting testicular cells
    1
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    sciencedirect.com/science/article/pii/S2666979X24000375
  29. Feb 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of synaptopodin impairs mGluR5 and protein synthesis–dependent mGluR-LTD at CA3-CA1 synapses
    1
    1. scibot 28 Feb 2024
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      DOI: 10.1093/pnasnexus/pgae062

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879843/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic and chemical disruption of amyloid precursor protein processing impairs zebrafish sleep maintenance
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    Dual roles of CCDC102A in governing centrosome duplication and cohesion
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    sciencedirect.com/science/article/pii/S221112472400024X
  33. Jan 2024
  34. www.sciencedirect.com www.sciencedirect.com
    Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo
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      DOI: 10.1016/j.stem.2023.12.003

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    sciencedirect.com/science/article/pii/S1934590923004332
  35. Nov 2023
  36. www.nature.com www.nature.com
    Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization
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      DOI: 10.1038/s41467-023-43180-8

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    nature.com/articles/s41467-023-43180-8
  37. Oct 2023
  38. www.sciencedirect.com www.sciencedirect.com
    MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis
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    sciencedirect.com/science/article/pii/S1534580723005129
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    Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method
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    sciencedirect.com/science/article/pii/S1534580723004951
  40. Sep 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Centrins control chicken cone cell lipid droplet dynamics through lipid-droplet-localized SPDL1
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    sciencedirect.com/science/article/pii/S1534580723004082
  42. Aug 2023
  43. www.sciencedirect.com www.sciencedirect.com
    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
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    sciencedirect.com/science/article/pii/S221112472300997X
  44. www.biorxiv.org www.biorxiv.org
    Loss of synaptopodin impairs mGluR5 and protein synthesis dependent mGluR-LTD at CA3-CA1 synapses
    1
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      DOI: 10.1101/2023.08.02.551676

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    biorxiv.org/content/10.1101/2023.08.02.551676v1
  45. Jul 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation
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    sciencedirect.com/science/article/pii/S2211124723008616
  47. Jun 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Spd-2 gene duplication reveals cell-type-specific pericentriolar material regulation
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      DOI: 10.1016/j.cub.2023.06.020

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    sciencedirect.com/science/article/pii/S0960982223007716
  49. www.embopress.org www.embopress.org
    A phylogenetic profiling approach identifies novel ciliogenesis genes in Drosophila and C. elegans
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      DOI: 10.15252/embj.2023113616

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    embopress.org/doi/10.15252/embj.2023113616
  50. May 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Antagonistic interactions among structured domains in the multivalent Bicc1-ANKS3-ANKS6 protein network govern phase transitioning of target mRNAs
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      DOI: 10.1016/j.isci.2023.106855

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    sciencedirect.com/science/article/pii/S258900422300932X
  52. www.sciencedirect.com www.sciencedirect.com
    Activation of endoplasmic reticulum stress in premature aging via the inner nuclear membrane protein SUN2
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      DOI: 10.1016/j.celrep.2023.112534

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    sciencedirect.com/science/article/pii/S2211124723005454
  53. Apr 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars
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      DOI: 10.1016/j.xgen.2023.100293

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    sciencedirect.com/science/article/pii/S2666979X23000599
  55. Feb 2023
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates
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      DOI: 10.7554/eLife.34959

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    ncbi.nlm.nih.gov/pmc/articles/PMC5976437/
  57. www.sciencedirect.com www.sciencedirect.com
    Centrosomal microtubule nucleation regulates radial migration of projection neurons independently of polarization in the developing brain
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      DOI: 10.1016/j.neuron.2023.01.020

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    sciencedirect.com/science/article/pii/S0896627323000703
  58. Dec 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch-dependent Abl signaling regulates cell motility during ommatidial rotation in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC9887719/
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    IFT-A structure reveals carriages for membrane protein transport into cilia
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      DOI: 10.1016/j.cell.2022.11.010

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    CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors
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  63. Oct 2022
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    A function for Ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission
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    Increased microtubule growth triggered by microvesicle-mediated paracrine signaling is required for melanoma cancer cell invasion
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    Stabilization of Spine Synaptopodin by mGluR1 Is Required for mGluR-LTD
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  83. Feb 2022
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    SENP2 suppresses browning of white adipose tissues by de-conjugating SUMO from C/EBPβ
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    The SH2 domain and kinase activity of JAK2 target JAK2 to centrosome and regulate cell growth and centrosome amplification
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    chinmo-mutant spermatogonial stem cells cause mitotic drive by evicting non-mutant neighbors from the niche
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    The related coactivator complexes SAGA and ATAC control embryonic stem cell self-renewal through acetyltransferase-independent mechanisms
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    NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
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    Control of Intestinal Cell Fate by Dynamic Mitotic Spindle Repositioning Influences Epithelial Homeostasis and Longevity
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    Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity
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    GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy
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  122. Mar 2021
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  125. Feb 2021
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    Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth
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    Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling
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  128. Dec 2020
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    Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions
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    The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina
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    CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression
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    Dynamic Buffering of Extracellular Chemokine by a Dedicated Scavenger Pathway Enables Robust Adaptation during Directed Tissue Migration
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    Wnt3a Stimulation Promotes Primary Ciliogenesis through β-Catenin Phosphorylation-Induced Reorganization of Centriolar Satellites
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    Cep97 Is Required for Centriole Structural Integrity and Cilia Formation in Drosophila
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    The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress
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    Promiscuous Binding of Microprotein Mozart1 to γ-Tubulin Complex Mediates Specific Subcellular Targeting to Control Microtubule Array Formation
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    Microtubule Nucleation Properties of Single Human γTuRCs Explained by Their Cryo-EM Structure
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    NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesisNCAM regulates temporal NPC specification
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    C3G localizes to mother centriole dependent on cenexin, and regulates centrosome duplication and primary cilia length
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    RABL6A is an essential driver of MPNSTs that negatively regulates the RB1 pathway and sensitizes tumor cells to CDK4/6 inhibitors
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      gamma-tubulin

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  149. Aug 2020
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    Excess centrosomes disrupt vascular lumenization and endothelial cell adherens junctions
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      anti-γ-tubulin

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    MZT Proteins Form Multi-Faceted Structural Modules in the γ-Tubulin Ring Complex
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      Anti-γ-tubulin, mouse monoclonal, clone GTU-88

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  152. Jan 2020
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    The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function
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    Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration
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    A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
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    The transcriptional repressor SNAI2 impairs neuroblastoma differentiation and inhibits response to retinoic acid therapy
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    Cul4 ubiquitin ligase cofactor DCAF12 promotes neurotransmitter release and homeostatic plasticity
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    Asymmetric Molecular Architecture of the Human γ-Tubulin Ring Complex
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    Replication Study: Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis
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    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
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    Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia
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    Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
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    Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication
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    Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity
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    Spindle-Length-Dependent HURP Localization Allows Centrosomes to Control Kinetochore-Fiber Plus-End Dynamics
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  169. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cordycepin improves behavioral‐LTP and dendritic structure in hippocampal CA1 area of rats
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    Control of Intestinal Cell Fate by Dynamic Mitotic Spindle Repositioning Influences Epithelial Homeostasis and Longevity
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    Chiral Cilia Orientation in the Left-Right Organizer
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    Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM
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      DOI: 10.1016/j.neuron.2019.02.009

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    CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1
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      DOI: 10.1016/j.celrep.2019.04.036

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  177. Nov 2018
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    WDR5 Stabilizes Actin Architecture to Promote Multiciliated Cell Formation
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    Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination
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  182. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Hypoxia negatively affects senescence in osteoclasts and delays osteoclastogenesis
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    Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown
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  184. elifesciences.org elifesciences.org
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    Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells
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    Atypical Cadherin Dachsous1b Interacts with Ttc28 and Aurora B to Control Microtubule Dynamics in Embryonic Cleavages
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    Mitochondria Restrict Growth of the Intracellular Parasite Toxoplasma gondii by Limiting Its Uptake of Fatty Acids
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atf3 links loss of epithelial polarity to defects in cell differentiation and cytoarchitecture
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      T6557

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    Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Method for the Acute and Rapid Degradation of Endogenous Proteins
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  192. europepmc.org europepmc.org
    Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells.
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  193. academic.oup.com academic.oup.com
    Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response
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  194. Nov 2017
  195. www.sciencedirect.com www.sciencedirect.com
    An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z β as an Essential Regulator of Spindle Orientation
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  196. www.sciencedirect.com www.sciencedirect.com
    Phospho-H1 Decorates the Inter-chromatid Axis and Is Evicted along with Shugoshin by SET during Mitosis
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    Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression
    1
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      Anti-gamma-tubulin, mouse monoclonalSigma-AldrichClone: T6557

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  198. link.springer.com link.springer.com
    IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents
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    Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy
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      AB_477584

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    Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding
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      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# T6557, RRID:AB_477584)

      SciCrunch record: RRID:AB_477584

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_477584 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627317300934
  201. www.sciencedirect.com www.sciencedirect.com
    NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres
    1
    1. scibot 08 Nov 2017
      AB_477584

      Curator: @Zeljana_Babic

      Resource used:

      (Sigma-Aldrich Cat# T6557, RRID:AB_477584)

      SciCrunch record: RRID:AB_477584

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_477584 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517300424
  202. www.sciencedirect.com www.sciencedirect.com
    Differential Routing of Mindbomb1 via Centriolar Satellites Regulates Asymmetric Divisions of Neural Progenitors
    1
    1. scibot 08 Nov 2017
      AB_477584

      Curator: @gabimpine

      Resource used:

      (Sigma-Aldrich Cat# T6557, RRID:AB_477584)

      SciCrunch record: RRID:AB_477584

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_477584 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627316310418
  203. www.sciencedirect.com www.sciencedirect.com
    Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision
    1
    1. scibot 08 Nov 2017
      AB_477584

      Curator: @gabimpine

      Resource used:

      (Sigma-Aldrich Cat# T6557, RRID:AB_477584)

      SciCrunch record: RRID:AB_477584

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_477584 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867416317482
  204. www.cell.com www.cell.com
    GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy
    1
    1. scibot 08 Nov 2017
      AB_477584

      Resource used:

      (Sigma-Aldrich Cat# T6557, RRID:AB_477584)

      SciCrunch record: RRID:AB_477584

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_477584
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    cell.com/action/showExperimentalProcedures
  205. elifesciences.org elifesciences.org
    Registered report: Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis
    1
    1. scibot 08 Nov 2017
      Mouse anti-γ-tubulin (clone GTU-88)

      Curator: @jcabotaj

      Resource used:

      (Sigma-Aldrich Cat# T6557, RRID:AB_477584)

      SciCrunch record: RRID:AB_477584

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_477584 RRIDCUR:Missing
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    elifesciences.org/content/4/e04796