309 Matching Annotations
  1. May 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells
    1
    1. scibot 06 May 2021
      RRID:AB_477629

      DOI: 10.1016/j.devcel.2021.02.020

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    sciencedirect.com/science/article/pii/S153458072100160X
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    Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis
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    1. scibot 05 May 2021
      RRID:AB_477629

      DOI: 10.1016/j.devcel.2020.09.011

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    sciencedirect.com/science/article/pii/S1534580720307139
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology
    1
    1. scibot 05 May 2021
      RRID:AB_477629

      DOI: 10.7554/eLife.66904

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    ncbi.nlm.nih.gov/pmc/articles/PMC8075583/
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    Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis
    1
    1. scibot 04 May 2021
      AB_477629

      DOI: 10.1016/j.devcel.2020.04.015

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    sciencedirect.com/science/article/pii/S1534580720303178
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    Tyrosine Phosphorylation of the Myosin Regulatory Light Chain Controls Non-muscle Myosin II Assembly and Function in Migrating Cells
    1
    1. scibot 01 May 2021
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      DOI: 10.1016/j.cub.2020.04.057

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    sciencedirect.com/science/article/pii/S096098222030573X
  7. Apr 2021
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    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
    1
    1. scibot 29 Apr 2021
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      DOI: 10.1016/j.cmet.2020.10.005

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    sciencedirect.com/science/article/pii/S1550413120305386
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    Coordinate regulation of the senescent state by selective autophagy
    1
    1. scibot 29 Apr 2021
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      DOI: 10.1016/j.devcel.2021.04.008

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    sciencedirect.com/science/article/pii/S1534580721003178
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    Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade
    1
    1. scibot 28 Apr 2021
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      DOI: 10.1016/j.molcel.2021.03.037

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    sciencedirect.com/science/article/pii/S109727652100232X
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    Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression
    1
    1. scibot 13 Apr 2021
      RRID:AB_477629

      DOI: 10.1016/j.molcel.2021.03.018

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    sciencedirect.com/science/article/pii/S1097276521002136
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    Functional interrogation of DNA damage response variants with base editing screens
    1
    1. scibot 12 Apr 2021
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      DOI: 10.1016/j.cell.2021.01.041

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    sciencedirect.com/science/article/pii/S0092867421000842
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    Reduced Thiamine Availability and Hyperglycemia Impair Thiamine Transport in Renal Glomerular Cells through Modulation of Thiamine Transporter 2
    1
    1. scibot 10 Apr 2021
      RRID:AB_477629

      DOI: 10.3390/biomedicines9040385

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    mdpi.com/2227-9059/9/4/385
  14. www.sciencedirect.com www.sciencedirect.com
    A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology
    1
    1. scibot 07 Apr 2021
      mouse anti‐vinculin

      DOI: 10.1016/j.ebiom.2021.103314

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    sciencedirect.com/science/article/pii/S2352396421001079
  15. www.nature.com www.nature.com
    Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling
    1
    1. scibot 06 Apr 2021
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      DOI: 10.1038/s41556-021-00654-5

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    nature.com/articles/s41556-021-00654-5
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    Protocol for analysis of integrin-mediated cell adhesion of lateral plate mesoderm cells isolated from zebrafish embryos
    1
    1. scibot 01 Apr 2021
      RRID:AB_477629

      DOI: 10.1016/j.xpro.2021.100428

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    sciencedirect.com/science/article/pii/S2666166721001350
  17. Mar 2021
  18. elifesciences.org elifesciences.org
    TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation
    1
    1. scibot 20 Mar 2021
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      DOI: 10.7554/eLife.62873

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    elifesciences.org/articles/62873
  19. www.sciencedirect.com www.sciencedirect.com
    MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage
    1
    1. scibot 01 Mar 2021
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      DOI: 10.1016/j.ccell.2020.12.010

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    sciencedirect.com/science/article/pii/S1535610820306589
  20. www.sciencedirect.com www.sciencedirect.com
    Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer
    1
    1. scibot 01 Mar 2021
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      DOI: 10.1016/j.cell.2020.12.031

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    sciencedirect.com/science/article/pii/S0092867420317530
  21. Feb 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Mesoscale Modeling and Single-Nucleosome Tracking Reveal Remodeling of Clutch Folding and Dynamics in Stem Cell Differentiation
    1
    1. scibot 28 Feb 2021
      RRID:AB_477629

      DOI: 10.1016/j.celrep.2020.108614

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    sciencedirect.com/science/article/pii/S221112472031603X
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation in amino-acid-poor environments is limited by tRNAGln charging
    1
    1. scibot 27 Feb 2021
      RRID:AB_477629

      DOI: 10.7554/eLife.62307

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    ncbi.nlm.nih.gov/pmc/articles/PMC7744096/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of the Extracellular Matrix Molecule Tenascin-C Leads to Absence of Reactive Gliosis and Promotes Anti-inflammatory Cytokine Expression in an Autoimmune Glaucoma Mouse Model
    1
    1. scibot 27 Feb 2021
      RRID:AB_477629

      DOI: 10.3389/fimmu.2020.566279

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    ncbi.nlm.nih.gov/pmc/articles/PMC7581917/
  25. www.nature.com www.nature.com
    Efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins
    1
    1. scibot 24 Feb 2021
      RRID:_AB:477629

      DOI: 10.1038/s41598-020-71550-5

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    nature.com/articles/s41598-020-71550-5
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of stress fibers through myosin-driven reorganization of the actin cortex
    1
    1. scibot 24 Feb 2021
      RRID:AB_477629

      DOI: 10.7554/eLife.60710

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    ncbi.nlm.nih.gov/pmc/articles/PMC7877910/
  27. www.sciencedirect.com www.sciencedirect.com
    Ctdnep1 and Eps8L2 regulate dorsal actin cables for nuclear positioning during cell migration
    1
    1. scibot 11 Feb 2021
      RRID:AB_477629

      DOI: 10.1016/j.cub.2021.01.007

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    sciencedirect.com/science/article/pii/S0960982221000403
  28. Jan 2021
  29. www.sciencedirect.com www.sciencedirect.com
    The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway
    1
    1. scibot 20 Jan 2021
      RRID:AB_477629

      DOI: 10.1016/j.celrep.2020.108659

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    sciencedirect.com/science/article/pii/S221112472031648X
  30. www.sciencedirect.com www.sciencedirect.com
    Increased demand for NAD+ relative to ATP drives aerobic glycolysis
    1
    1. scibot 05 Jan 2021
      RRID:AB_477629

      DOI: 10.1016/j.molcel.2020.12.012

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    sciencedirect.com/science/article/pii/S1097276520309047
  31. Dec 2020
  32. www.sciencedirect.com www.sciencedirect.com
    The ubiquitin ligase RFWD3 is required for translesion DNA synthesis
    1
    1. scibot 16 Dec 2020
      RRID:AB_477629

      DOI: 10.1016/j.molcel.2020.11.029

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    sciencedirect.com/science/article/pii/S1097276520308297
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism
    1
    1. scibot 12 Dec 2020
      RRID:AB_477629

      DOI: 10.7554/eLife.59258

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    ncbi.nlm.nih.gov/pmc/articles/PMC7723411/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MASTL promotes cell contractility and motility through kinase-independent signaling
    1
    1. scibot 07 Dec 2020
      RRID:AB_477629

      DOI: 10.1083/jcb.201906204

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    ncbi.nlm.nih.gov/pmc/articles/PMC7265322/
  35. www.sciencedirect.com www.sciencedirect.com
    BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis
    1
    1. scibot 07 Dec 2020
      RRID:AB_477629

      DOI: 10.1016/j.molcel.2020.10.040

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    sciencedirect.com/science/article/pii/S1097276520307747
  36. Nov 2020
  37. elifesciences.org elifesciences.org
    GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis
    1
    1. scibot 21 Nov 2020
      RRID:AB_477629

      DOI: 10.7554/eLife.62731

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    elifesciences.org/articles/62731
  38. Oct 2020
  39. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Coxsackievirus B Type 4 Infection in β Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via Pdx1 Silencing
    1
    1. scibot 27 Oct 2020
      RRID:AB_477629

      DOI: 10.1016/j.xcrm.2020.100125

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    pubmed.ncbi.nlm.nih.gov/33205075/
  40. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Gene therapy with secreted acid alpha-glucosidase rescues Pompe disease in a novel mouse model with early-onset spinal cord and respiratory defects
    1
    1. scibot 13 Oct 2020
      RRID:AB_477629

      DOI: 10.1016/j.ebiom.2020.103052

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    pubmed.ncbi.nlm.nih.gov/33039711/
  41. Sep 2020
  42. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Divergent Roles of PI3K Isoforms in PTEN-Deficient Glioblastomas
    1
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      RRID:AB_477629

      DOI: 10.1016/j.celrep.2020.108196

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    pubmed.ncbi.nlm.nih.gov/32997991/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Telophase correction refines division orientation in stratified epithelia
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      RRID:AB_477629

      DOI: 10.7554/eLife.49249

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    ncbi.nlm.nih.gov/pmc/articles/PMC6959978/
  44. www.sciencedirect.com www.sciencedirect.com
    Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness
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      RRID:AB_477629

      DOI: 10.1016/j.celrep.2020.107731

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    sciencedirect.com/science/article/pii/S2211124720307117
  45. www.sciencedirect.com www.sciencedirect.com
    Imprinted Maternally Expressed microRNAs Antagonize Paternally Driven Gene Programs in Neurons
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      RRID:AB_477629

      DOI: 10.1016/j.molcel.2020.01.020

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    sciencedirect.com/science/article/pii/S1097276520300411
  46. www.sciencedirect.com www.sciencedirect.com
    Evidence That STK19 Is Not an NRAS-dependent Melanoma Driver
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    1. scibot 23 Sep 2020
      RRID:AB_477629

      DOI: 10.1016/j.cell.2020.04.014

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    sciencedirect.com/science/article/pii/S0092867420304761
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
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      RRID:AB_477629

      DOI: 10.1038/s41467-019-14085-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC6965108/
  48. www.sciencedirect.com www.sciencedirect.com
    Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
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    1. scibot 17 Sep 2020
      RRID:AB_477629

      DOI: 10.1016/j.celrep.2020.107764

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    sciencedirect.com/science/article/pii/S2211124720307440
  49. www.cell.com www.cell.com
    PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin
    2
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      RRID:AB_477629

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    Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity
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    Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
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    Next‐generation sequencing reveals a novel role of lysine‐specific demethylase 1 in adhesion of rhabdomyosarcoma cells
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    Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming
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    The SUMO Isopeptidase SENP6 Functions as a Rheostat of Chromatin Residency in Genome Maintenance and Chromosome Dynamics
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    Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation
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    Neurexophilin4 is a selectively expressed α-neurexin ligand that modulates specific cerebellar synapses and motor functions
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    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
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    Circulating blood cellular glucose transporters – Surrogate biomarkers for neonatal hypoxic ischemic encephalopathy assessed by novel scoring systems
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    Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability
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    Shortening the Half-Life of Cas9 Maintains Its Gene Editing Ability and Reduces Neuronal Toxicity
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    MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody
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  93. www.sciencedirect.com www.sciencedirect.com
    Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma
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  94. www.sciencedirect.com www.sciencedirect.com
    Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  96. journals.plos.org journals.plos.org
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  97. www.sciencedirect.com www.sciencedirect.com
    A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation
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  98. www.sciencedirect.com www.sciencedirect.com
    An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns
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    c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism
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  103. www.nature.com www.nature.com
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    Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions
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    mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis
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    As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid
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    Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
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  110. europepmc.org europepmc.org
    Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth.
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  111. Nov 2017
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    Carbon Black Nanoparticles Inhibit Aromatase Expression and Estradiol Secretion in Human Granulosa Cells Through the ERK1/2 Pathway
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    Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition
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  114. www.jneurosci.org www.jneurosci.org
    Calpain-Mediated Proteolysis of Talin and FAK Regulates Adhesion Dynamics Necessary for Axon Guidance
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    The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling
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    Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules
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    Crosstalk between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis
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    Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores
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    Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model
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