97 Matching Annotations
  1. May 2024
  2. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
    1
    1. scibot 24 May 2024
      RRID:AB_490890

      DOI: 10.1126/scisignal.adh4475

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    science.org/doi/10.1126/scisignal.adh4475
  3. Apr 2024
  4. dx.doi.org dx.doi.org
    β-cell insulin resistance plays a causal role in fat-induced β-cell dysfunction in vitro and in vivo
    1
    1. scibot 10 Apr 2024
      AB_490890

      DOI: 10.1210/endocr/bqae044

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    dx.doi.org/10.1210/endocr/bqae044
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Creatine and low-dose lithium supplementation separately alter energy expenditure, body mass and adipose metabolism for the promotion of thermogenesis
    2
    1. scibot 03 Apr 2024
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      DOI: 10.1016/j.isci.2024.109468

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    2. scibot 03 Apr 2024
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      DOI: 10.1016/j.isci.2024.109468

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    ncbi.nlm.nih.gov/pmc/articles/PMC10973579/
  6. Feb 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity
    1
    1. scibot 27 Feb 2024
      Cell Signaling Technology#9315

      DOI: 10.1016/j.isci.2024.109121

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    sciencedirect.com/science/article/pii/S2589004224003420
  8. Jul 2023
  9. www.sciencedirect.com www.sciencedirect.com
    mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching
    1
    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112868

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    sciencedirect.com/science/article/pii/S2211124723008793
  10. Jun 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.isci.2023.107047

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    sciencedirect.com/science/article/pii/S2589004223011240
  12. www.sciencedirect.com www.sciencedirect.com
    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
    1
    1. scibot 09 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112616

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    sciencedirect.com/science/article/pii/S2211124723006277
  13. academic.oup.com academic.oup.com
    Increased fibrosis in white adipose tissue of male and female bGH transgenic mice appears independent of TGF-β action
    1
    1. scibot 02 Jun 2023
      AB_490890

      DOI: 10.1210/endocr/bqad038

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    academic.oup.com/endo/article/164/5/bqad038/7069260
  14. May 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity
    1
    1. scibot 18 May 2023
      RRID:AB_490890

      DOI: 10.1210/jendso/bvad057

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    ncbi.nlm.nih.gov/pmc/articles/PMC10185814/
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
    1
    1. scibot 05 May 2023
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      DOI: 10.1002/cac2.12332

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    onlinelibrary.wiley.com/doi/10.1002/cac2.12332
  17. www.mdpi.com www.mdpi.com
    GM1 Oligosaccharide Efficacy in Parkinson’s Disease: Protection against MPTP
    1
    1. scibot 04 May 2023
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      DOI: 10.3390/biomedicines11051305

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    mdpi.com/2227-9059/11/5/1305
  18. Apr 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
    1
    1. scibot 09 Apr 2023
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      DOI: 10.7554/eLife.78629

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    ncbi.nlm.nih.gov/pmc/articles/PMC10069870/
  20. Mar 2023
  21. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 03 Mar 2023
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      DOI: 10.1111/bph.16046

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16046
  22. www.sciencedirect.com www.sciencedirect.com
    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
    1
    1. scibot 02 Mar 2023
      RRID:AB_490890

      DOI: 10.1016/j.celrep.2023.112188

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    sciencedirect.com/science/article/pii/S2211124723001997
  23. Feb 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Hexane fraction of Prunus japonica thunb. Seed extract enhances boar sperm motility via CatSper ion channel
    1
    1. scibot 10 Feb 2023
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      DOI: 10.1016/j.heliyon.2023.e13616

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    sciencedirect.com/science/article/pii/S240584402300823X
  25. Jan 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism
    1
    1. scibot 20 Jan 2023
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      DOI: 10.1016/j.isci.2022.105911

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    ncbi.nlm.nih.gov/pmc/articles/PMC9843443/
  27. www.sciencedirect.com www.sciencedirect.com
    SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2
    1
    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111984

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    sciencedirect.com/science/article/pii/S2211124722018885
  28. Dec 2022
  29. www.sciencedirect.com www.sciencedirect.com
    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
    1
    1. scibot 08 Dec 2022
      RRID:AB_490890

      DOI: 10.1016/j.celrep.2022.111759

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    sciencedirect.com/science/article/pii/S2211124722016424
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PERIOD 2 Regulates Low Dose Radioprotection via PER2/pGSK3β/β-Catenin/Per2 Loop
    1
    1. scibot 02 Dec 2022
      RRID:AB_490890

      DOI: 10.1016/j.isci.2022.105546

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    ncbi.nlm.nih.gov/pmc/articles/PMC9708791/
  31. Sep 2022
  32. www.sciencedirect.com www.sciencedirect.com
    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling
    1
    1. scibot 27 Sep 2022
      RRID:AB_490890

      DOI: 10.1016/j.jbc.2022.102532

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    sciencedirect.com/science/article/pii/S0021925822009759
  33. www.authorea.com www.authorea.com
    ISX9, a small molecule targeting Axin, activates Wnt/β-catenin signaling and promotes hair regrowth
    1
    1. scibot 22 Sep 2022
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      DOI: 10.22541/au.166126327.70529620/v1

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    authorea.com/users/503180/articles/582965-isx9-a-small-molecule-targeting-axin-activates-wnt-β-catenin-signaling-and-promotes-hair-regrowth
  34. Aug 2022
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK3β Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia
    1
    1. scibot 27 Aug 2022
      AB_490890

      DOI: 10.3390/ijms23169375

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    ncbi.nlm.nih.gov/pmc/articles/PMC9409400/
  36. Jul 2022
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Altered amyloid precursor protein, tau-regulatory proteins, neuronal numbers and behaviour, but no tau pathology, synaptic and inflammatory changes or memory deficits, at 1-month following repetitive mild traumatic brain injury
    1
    1. scibot 27 Jul 2022
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      DOI: 10.1111/ejn.15752

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    onlinelibrary.wiley.com/doi/10.1111/ejn.15752
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Potassium channel Kir4.1 regulates oligodendrocyte differentiation via intracellular pH regulation
    1
    1. scibot 02 Jul 2022
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      DOI: 10.1002/glia.24240

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    onlinelibrary.wiley.com/doi/10.1002/glia.24240
  39. Jun 2022
  40. journals.lww.com journals.lww.com
    Icariin ameliorates memory deficits through regulating... : Neural Regeneration Research
    1
    1. scibot 24 Jun 2022
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      DOI: 10.4103/1673-5374.344840

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    journals.lww.com/nrronline/Fulltext/2023/01000/Icariin_ameliorates_memory_deficits_through.39.aspx
  41. May 2022
  42. www.sciencedirect.com www.sciencedirect.com
    c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity
    1
    1. scibot 19 May 2022
      RRID:AB_490890

      DOI: 10.1016/j.isci.2022.104325

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    sciencedirect.com/science/article/pii/S258900422200596X
  43. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
    1
    1. scibot 05 May 2022
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      DOI: 10.1186/s13024-022-00526-y

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    link.springer.com/article/10.1186/s13024-022-00526-y
  44. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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    1. scibot 05 May 2022
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      DOI: 10.1016/j.cell.2022.04.014

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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  45. Apr 2022
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney
    1
    1. scibot 29 Apr 2022
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      DOI: 10.1038/s41467-022-29644-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC9038906/
  47. Feb 2022
  48. www.sciencedirect.com www.sciencedirect.com
    A mouse model of inherited choline kinase β-deficiency presents with specific cardiac abnormalities and a predisposition to arrhythmia
    1
    1. scibot 13 Feb 2022
      Cell signaling, Cat#9315

      DOI: 10.1016/j.jbc.2022.101716

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    sciencedirect.com/science/article/pii/S0021925822001569
  49. www.sciencedirect.com www.sciencedirect.com
    Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity
    1
    1. scibot 13 Feb 2022
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      DOI: 10.1016/j.isci.2022.103859

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    sciencedirect.com/science/article/pii/S2589004222001298
  50. Sep 2021
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Doxazosin and erlotinib have anticancer effects in the endometrial cancer cell and important roles in ERα and Wnt/β-catenin signaling pathways
    1
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      DOI: 10.1002/jbt.22905

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    onlinelibrary.wiley.com/doi/10.1002/jbt.22905
  52. Aug 2021
  53. www.sciencedirect.com www.sciencedirect.com
    The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway
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    1. scibot 17 Aug 2021
      9315

      DOI: 10.1016/j.apsb.2021.08.015

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    sciencedirect.com/science/article/pii/S2211383521003051
  54. www.physiology.org www.physiology.org
    Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner
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    1. scibot 14 Aug 2021
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      DOI: 10.1152/ajpendo.00496.2018

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    physiology.org/doi/abs/10.1152/ajpendo.00496.2018
  55. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1111/jnc.14081

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14081
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    1. scibot 09 Aug 2021
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      DOI: 10.1111/jnc.14537

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14537
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.celrep.2018.09.045

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    ncbi.nlm.nih.gov/pmc/articles/PMC6338448/
  58. Jul 2021
  59. academic.oup.com academic.oup.com
    Intrinsic High Aerobic Capacity in Male Rats Protects Against Diet-Induced Insulin Resistance
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      DOI: 10.1210/en.2019-00118

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    academic.oup.com/endo/article/160/5/1179/5434897
  60. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.ebiom.2019.03.021

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    Exogenous C-type natriuretic peptide therapy for impaired skeletal growth in a murine model of glucocorticoid treatment
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy
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  65. May 2021
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    Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors
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    DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1
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    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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  71. Mar 2021
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  73. Feb 2021
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    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
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    Deletion of hippocampal Glucocorticoid receptors unveils sex-biased microRNA expression and neuronal morphology alterations in mice
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  76. Jan 2021
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  78. Dec 2020
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    Intranasal deferoxamine can improve memory in healthy C57 mice, suggesting a partially non‐disease‐specific pathway of functional neurologic improvement
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  80. Nov 2020
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    Effect of Hyperbaric Oxygen Therapy on Acute Liver Injury and Survival in a Rat Cecal Slurry Peritonitis Model
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  82. Oct 2020
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    Tideglusib attenuates growth of neuroblastoma cancer stem/progenitor cells in vitro and in vivo by specifically targeting GSK-3β
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  85. Sep 2020
  86. dev.biologists.org dev.biologists.org
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    A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation
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  89. www.mdpi.com www.mdpi.com
    Melatonin Induces Melanogenesis in Human SK-MEL-1 Melanoma Cells Involving Glycogen Synthase Kinase-3 and Reactive Oxygen Species
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    TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation
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    Effect of angiotensin II and angiotensin‐(1–7) on proliferation of stem cells from human dental apical papilla
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  95. Jan 2020
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    Usp9X Controls Ankyrin-Repeat Domain Protein Homeostasis during Dendritic Spine Development
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    Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling
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    N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor
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    Activation of GSK3β induced by recall of cocaine reward memories is dependent on GluN2A/B NMDA receptor signaling
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    Pum2 Shapes the Transcriptome in Developing Axons through Retention of Target mRNAs in the Cell Body
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    SFRPs Are Biphasic Modulators of Wnt-Signaling-Elicited Cancer Stem Cell Properties beyond Extracellular Control
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    Role of hepatic glucocorticoid receptor in metabolism in models of 5αR1 Deficiency in Male Mice
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    Hepatic gluconeogenic response to single and long-term SGLT2 inhibition in lean/obese male hepatic G6pc-reporter mice
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    Intrinsic High Aerobic Capacity in Male Rats Protects Against Diet-Induced Insulin Resistance
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    Light Entrains Diurnal Changes in Insulin Sensitivity of Skeletal Muscle via Ventromedial Hypothalamic Neurons
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  107. Nov 2018
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    Ouabain increases neuronal branching in hippocampus and improves spatial memory
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    sciencedirect.com/science/article/pii/S0028390818304799
  110. link.springer.com link.springer.com
    Early-Ethanol Exposure Induced Region-Specific Changes in Metabolic Proteins in the Rat Brain: A Proteomics Study
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      Curator: @evieth

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    link.springer.com/article/10.1007/s12031-018-1097-z
  111. www.sciencedirect.com www.sciencedirect.com
    Maternal separation stress reduced prenatal-ethanol-induced increase in exploratory behaviour and extracellular signal-regulated kinase activity
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    sciencedirect.com/science/article/pii/S0166432818300573
  112. www.sciencedirect.com www.sciencedirect.com
    Juvenile treatment with mGluR2/3 agonist prevents schizophrenia-like phenotypes in adult by acting through GSK3β
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  113. academic.oup.com academic.oup.com
    FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2
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  114. europepmc.org europepmc.org
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lithium Inhibits GSK3β and Augments GluN2A Receptor Expression in the Prefrontal Cortex
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  116. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Maternal exercise modifies body composition and energy substrates handling in high‐fat/high‐sucrose diet fed male offspring
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    onlinelibrary.wiley.com/doi/10.1113/JP274739/full
  117. Nov 2017
  118. www.sciencedirect.com www.sciencedirect.com
    Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes
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  119. www.nature.com www.nature.com
    ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury
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    nature.com/articles/s41598-017-11654-7
  120. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Heparan sulfate alterations in extracellular matrix structures and fibroblast growth factor‐2 signaling impairment in the aged neurogenic niche
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14081/full
  121. academic.oup.com academic.oup.com
    Effects of the Activation of Three Major Hepatic Akt Substrates on Glucose Metabolism in Male Mice
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  122. www.sciencedirect.com www.sciencedirect.com
    Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells
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  123. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brief isoflurane anesthesia regulates striatal AKT‐GSK3β signaling and ameliorates motor deficits in a rat model of early‐stage Parkinson′s disease
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  124. www.sciencedirect.com www.sciencedirect.com
    Angiotensin-II-induced Muscle Wasting is Mediated by 25-Hydroxycholesterol via GSK3β Signaling Pathway
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  125. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Early ethanol exposure and vinpocetine treatment alter learning‐ and memory‐related proteins in the rat hippocampus and prefrontal cortex
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23894/full
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
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  127. www.tandfonline.com www.tandfonline.com
    Mice lacking circadian clock components display different mood-related behaviors and do not respond uniformly to chronic lithium treatment: Chronobiology International: Vol 32, No 8
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    tandfonline.com/doi/full/10.3109/07420528.2015.1062024