Hypothesis

10 Matching Annotations

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HUWE1 stimulates mTORC1 activity by enhancing Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis

1
1. scibot 11 Oct 2025
  
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  RRID:AB_490956
  
  DOI: 10.1016/j.celrep.2025.116382
  
  Resource: (Cell Signaling Technology Cat# 3617, RRID:AB_490956)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_490956
  
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  RRID:AB_490956
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RRID:AB_490956

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scibot

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sciencedirect.com/science/article/pii/S2211124725011532
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TNF‐α‐Driven Changes in Polarized EGF Receptor Trafficking Facilitate Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling From the Apical Surface of MDCK Epithelial Cells

1
1. scibot 20 May 2025
  
  in Public
  
  AB_490956
  
  DOI: 10.1111/tra.70005
  
  Resource: (Cell Signaling Technology Cat# 3617, RRID:AB_490956)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_490956
  
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  RRID:AB_490956
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12052438/
Jun 2024
www.sciencedirect.com www.sciencedirect.com

PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer

1
1. scibot 21 Jun 2024
  
  in Public
  
  RRID:AB_490956
  
  DOI: 10.1016/j.cmet.2024.05.015
  
  Resource: (Cell Signaling Technology Cat# 3617, RRID:AB_490956)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_490956
  
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  RRID:AB_490956
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RRID:AB_490956

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scibot

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sciencedirect.com/science/article/pii/S1550413124001918
May 2024
www.sciencedirect.com www.sciencedirect.com

Leucyl-tRNA synthetase contributes to muscle weakness through mTORC1 activation and autophagy suppression in a mouse model of Duchenne Muscular Dystrophy

1
1. scibot 17 May 2024
  
  in Public
  
  RRID: AB_490956
  
  DOI: 10.1016/j.ajpath.2024.04.006
  
  Resource: (Cell Signaling Technology Cat# 3617, RRID:AB_490956)
  
  Curator: @abever99
  
  SciCrunch record: RRID:AB_490956
  
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  RRID:AB_490956
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scibot

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sciencedirect.com/science/article/pii/S0002944024001743
Apr 2023
www.sciencedirect.com www.sciencedirect.com

Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration

1
1. scibot 27 Apr 2023
  
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  RRID:AB_490956
  
  DOI: 10.1016/j.neuron.2023.04.006
  
  Resource: (Cell Signaling Technology Cat# 3617, RRID:AB_490956)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_490956
  
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sciencedirect.com/science/article/pii/S0896627323002684
Sep 2021
www.sciencedirect.com www.sciencedirect.com

KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis

1
1. scibot 22 Sep 2021
  
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  RRID:AB_490956
  
  DOI: 10.1016/j.molcel.2021.09.001
  
  Resource: (Cell Signaling Technology Cat# 3617, RRID:AB_490956)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_490956
  
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sciencedirect.com/science/article/pii/S1097276521007358
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb

1
1. scibot 13 Jan 2020
  
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  RRID:AB_490956
  
  DOI: 10.1016/j.immuni.2019.10.001
  
  Resource: (Cell Signaling Technology Cat# 3617, RRID:AB_490956)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_490956
  
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  RRID:AB_490956 RRIDCUR:Validated
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RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S1074761319304182
www.sciencedirect.com www.sciencedirect.com

Lysosome Positioning Influences mTORC2 and AKT Signaling

1
1. scibot 12 Jan 2020
  
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  RRID:AB_490956
  
  DOI: 10.1016/j.molcel.2019.05.009
  
  Resource: (Cell Signaling Technology Cat# 3617, RRID:AB_490956)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_490956
  
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  RRID:AB_490956 RRIDCUR:Validated
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RRID:AB_490956

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1097276519303624
Nov 2018
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Systematic Functional Annotation of Somatic Mutations in Cancer

1
1. scibot 05 Nov 2018
  
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  RRID:AB_490956
  
  Resource used:
  
  (Cell Signaling Technology Cat# 3617S, RRID:AB_490956)
  
  SciCrunch record: RRID:AB_490956
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_490956
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RRID:AB_490956

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC5926201/
academic.oup.com academic.oup.com

Glucocorticoid Receptor Signaling Impairs Protein Turnover Regulation in Hypoxia-Induced Muscle Atrophy in Male Mice

1
1. scibot 05 Nov 2018
  
  in Public
  
  AB_490956
  
  Curator: @evieth
  
  Resource used:
  
  (Cell Signaling Technology Cat# 3617S, RRID:AB_490956)
  
  SciCrunch record: RRID:AB_490956
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_490956 RRIDCUR:Validated
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RRID:AB_490956

RRIDCUR:Validated

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scibot

URL

academic.oup.com/endo/article/159/1/519/4562294