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Aug 2025
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Tissue-specific I-Smad mechanisms revealed by structure-function analysis in Drosophila

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  DOI: 10.1101/2025.06.20.660739
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12262408/
Jul 2025
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Tissue-specific I-Smad mechanisms revealed by structure-function analysis in Drosophila

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  DOI: 10.1101/2025.06.20.660739
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12262408/
May 2025
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Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice

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1. scibot 30 May 2025
  
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  DOI: 10.7554/eLife.105018
  
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elifesciences.org/articles/105018
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Lineage-specific CDK activity dynamics characterize early mammalian development

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  DOI: 10.1016/j.celrep.2025.115558
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12070373/
Apr 2025
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Preventing and correcting polycystic ovary syndrome by targeting anti-Müllerian hormone signaling in minipuberty and adulthood in mice

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sciencedirect.com/science/article/pii/S1550413125001160
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Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice

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1. scibot 03 Apr 2025
  
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  DOI: 10.7554/eLife.105018.2
  
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elifesciences.org/reviewed-preprints/105018
Mar 2025
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BMP-dependent patterning of ectoderm tissue material properties modulates lateral mesendoderm cell migration during early zebrafish gastrulation

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115387
  
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sciencedirect.com/science/article/pii/S2211124725001585
Feb 2025
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Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway

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1. scibot 14 Feb 2025
  
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  DOI: 10.7554/eLife.97268
  
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elifesciences.org/articles/97268
Dec 2024
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1-s2.0-S2589004224028980-main-html.html

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1. scibot 24 Dec 2024
  
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52.53.155.43/ed615e5caccdde4f00468a53c221fcd3b0c1a15a/1-s2.0-S2589004224028980-main-html.html
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Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to early lethality in mice

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1. scibot 22 Dec 2024
  
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  DOI: 10.1101/2024.10.08.617306
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11482978/
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Self-organized pattern formation in the developing mouse neural tube by a temporal relay of BMP signaling

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.devcel.2024.10.024
  
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sciencedirect.com/science/article/pii/S1534580724006646
Nov 2024
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Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity

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1. scibot 26 Nov 2024
  
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  DOI: 10.7554/eLife.91988
  
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elifesciences.org/articles/91988
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ARF alters PAF1 complex integrity to selectively repress oncogenic transcription programs upon p53 loss

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1. scibot 17 Nov 2024
  
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  DOI: 10.1016/j.molcel.2024.10.020
  
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sciencedirect.com/science/article/pii/S1097276524008608
Jul 2024
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A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins

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1. scibot 27 Jul 2024
  
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  DOI: 10.1016/j.celrep.2023.112842
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10962759/
Mar 2024
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The TET-Sall4-BMP regulatory axis controls craniofacial cartilage development

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  DOI: 10.1016/j.celrep.2024.113873
  
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sciencedirect.com/science/article/pii/S2211124724002018
Feb 2024
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Diffusible fraction of niche BMP ligand safeguards stem-cell differentiation

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1. scibot 11 Feb 2024
  
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  DOI: 10.1038/s41467-024-45408-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10850516/
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Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis

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1. scibot 06 Feb 2024
  
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  DOI: 10.1101/2023.11.21.568157
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10690271/
Jan 2024
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FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophy

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1. scibot 12 Jan 2024
  
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  DOI: 10.1016/j.xcrm.2023.101306
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10772350/
Dec 2023
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ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors

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1. scibot 20 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113541
  
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sciencedirect.com/science/article/pii/S221112472301553X
Oct 2023
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Transgene directed induction of a stem cell-derived human embryo model

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1. scibot 13 Oct 2023
  
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  DOI: 10.1101/2023.06.15.545082
  
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52.53.155.43/5a401c55d861c2dcc062c9d148face33c192a62e/2023.06.15.545082v1.full-html.html
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Typhoid toxin hijacks Wnt5a to establish host senescence and Salmonella infection

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113181
  
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Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification

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1. scibot 06 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.107887
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10522999/
Sep 2023
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ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer

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1. scibot 29 Sep 2023
  
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  DOI: 10.3389/fcell.2023.1271178
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10520719/
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Fluid shear stress-modulated chromatin accessibility reveals the mechano-dependency of endothelial SMAD1/5-mediated gene transcription

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1. scibot 09 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107405
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10481294/
Jul 2023
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A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins

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1. scibot 22 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112842
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10962759/
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Cancer-associated mesothelial cells are regulated by the anti-Müllerian hormone axis

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1. scibot 15 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112730
  
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sciencedirect.com/science/article/pii/S2211124723007416
Jun 2023
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Loss of TJP1 disrupts gastrulation patterning and increases differentiation toward the germ cell lineage in human pluripotent stem cells

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  DOI: 10.1016/j.devcel.2023.05.019
  
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sciencedirect.com/science/article/pii/S1534580723002654
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ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer

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  DOI: 10.1101/2023.06.13.544797
  
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biorxiv.org/content/10.1101/2023.06.13.544797v1
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Acetate controls endothelial-to-mesenchymal transition

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.cmet.2023.05.010
  
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5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling

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  DOI: 10.1016/j.celrep.2023.112560
  
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sciencedirect.com/science/article/pii/S2211124723005715
May 2023
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BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage

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1. scibot 19 May 2023
  
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  DOI: 10.1242/dev.201450
  
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52.53.155.43/dd2974174e67d65ed3a779c744ae7b3f60cd7f18/RRID11-html.html
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Cross-activation of FGF, NODAL, and WNT pathways constrains BMP-signaling-mediated induction of the totipotent state in mouse embryonic stem cells

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1. scibot 03 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112438
  
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sciencedirect.com/science/article/pii/S2211124723004497
Apr 2023
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High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells

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1. scibot 25 Apr 2023
  
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  DOI: 10.1038/s41598-023-33352-3
  
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link.springer.com/article/10.1038/s41598-023-33352-3
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Smooth muscle contributes to the development and function of a layered intestinal stem cell niche

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1. scibot 20 Apr 2023
  
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  DOI: 10.1016/j.devcel.2023.02.012
  
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sciencedirect.com/science/article/pii/S1534580723000709
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Heterodimerization-dependent secretion of bone morphogenetic proteins in Drosophila

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1. scibot 13 Apr 2023
  
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  DOI: 10.1016/j.devcel.2023.03.008
  
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sciencedirect.com/science/article/pii/S1534580723001041
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Graded BMP signaling within intestinal crypt architecture directs self-organization of the Wnt-secreting stem cell niche

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1. scibot 07 Apr 2023
  
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FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells

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Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition

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Neuroinflammatory disease disrupts the blood-CNS barrier via crosstalk between proinflammatory and endothelial-to-mesenchymal-transition signaling

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Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer

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Sox2 in the dermal papilla regulates hair follicle pigmentation

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BMP-gated cell-cycle progression drives anoikis during mesenchymal collective migration

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Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer’s model

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Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development

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Escargot controls somatic stem cell maintenance through the attenuation of the insulin receptor pathway in Drosophila

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Mechanical feedback defines organizing centers to drive digit emergence

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The NDNF-like factor Nord is a Hedgehog-induced extracellular BMP modulator that regulates Drosophila wing patterning and growth

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Targeted search for scaling genes reveals matrix metalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos

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Tumor-derived MMPs regulate cachexia in a Drosophila cancer model

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RSPO2 inhibits BMP signaling to promote self-renewal in acute myeloid leukemia

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Hormonally regulated myogenic miR-486 influences sex-specific differences in cancer-induced skeletal muscle defects

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Untitled document

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Pinhead antagonizes Admp to promote notochord formation

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Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport

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MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling

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The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

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O-GlcNAcylation Dampens Dpp/BMP Signaling to Ensure Proper Drosophila Embryonic Development

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Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury

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Capturing human trophoblast development with naive pluripotent stem cells in vitro

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Identification of FoxP circuits involved in locomotion and object fixation in Drosophila

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High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures

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GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth

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Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors

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Phosphorylation‐dependent osterix degradation negatively regulates osteoblast differentiation

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  anti‐p‐Smad
  
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Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis

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Smooth Muscle Differentiation Is Essential for Airway Size, Tracheal Cartilage Segmentation, but Dispensable for Epithelial Branching

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Spatiotemporal Decline of BMP Signaling Activity in Neural Progenitors Mediates Fate Transition and Safeguards Neurogenesis

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Zebrafish embryonic explants undergo genetically encoded self-assembly

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Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates

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GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells

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Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation

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  DOI: 10.7554/eLife.55596
  
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Inhibition of the catalytic subunit of DNA‐dependent protein kinase (DNA‐PKcs) stimulates osteoblastogenesis by potentiating bone morphogenetic protein 2 (BMP2) responses

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Dkk1 Controls Cell-Cell Interaction through Regulation of Non-nuclear β-Catenin Pools

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Recruitment of Adult Precursor Cells Underlies Limited Repair of the Infected Larval Midgut in Drosophila

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Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2

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Enteroid Monolayers Reveal an Autonomous WNT and BMP Circuit Controlling Intestinal Epithelial Growth and Organization

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Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage

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A novel role for Ets4 in axis specification and cell migration in the spider Parasteatoda tepidariorum

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Basement Membrane Manipulation in Drosophila Wing Discs Affects Dpp Retention but Not Growth Mechanoregulation

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Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers

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A novel and robust conditioning lesion induced by ethidium bromide

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