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  1. Last 7 days
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    One-carbon unit supplementation fuels purine synthesis in tumor-infiltrating T cells and augments checkpoint blockade
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    1. scibot 17 May 2024
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    An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis
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    sciencedirect.com/science/article/pii/S0092867424004136
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    The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory T cells
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    1. scibot 14 May 2024
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    sciencedirect.com/science/article/pii/S2211124724005503
  5. Mar 2024
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    Adipose stem cells control obesity-induced T cell infiltration into adipose tissue
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    sciencedirect.com/science/article/pii/S2211124724002912
  7. Jan 2024
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    Bispecific dendritic-T cell engager potentiates anti-tumor immunity
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    1. scibot 19 Jan 2024
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    sciencedirect.com/science/article/pii/S0092867423013430
  9. Oct 2023
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    Targeting VCP potentiates immune checkpoint therapy for colorectal cancer
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    sciencedirect.com/science/article/pii/S221112472301330X
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    CD4+ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling
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    1. scibot 20 Oct 2023
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      DOI: 10.1101/2023.09.01.555931

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    Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1
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    1. scibot 17 Oct 2023
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    Systematic investigation of mitochondrial transfer between cancer cells and T cells at single-cell resolution
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    1. scibot 13 Oct 2023
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    sciencedirect.com/science/article/pii/S1535610823003197
  14. Aug 2023
  15. 52.53.155.43 52.53.155.43
    A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis
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  16. 52.53.155.43 52.53.155.43
    CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells
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    1. scibot 17 Aug 2023
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    2. scibot 11 Aug 2023
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  17. 52.53.155.43 52.53.155.43
    Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues
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    1. scibot 12 Aug 2023
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  18. Jul 2023
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    The splicing isoform Foxp3Δ2 differentially regulates tTreg and pTreg homeostasis
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    1. scibot 27 Jul 2023
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    sciencedirect.com/science/article/pii/S2211124723008884
  20. Jun 2023
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    Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation
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    sciencedirect.com/science/article/pii/S1074761323002273
  22. Apr 2023
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    An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses
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    Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance
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    A neutrophil response linked to tumor control in immunotherapy
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    sciencedirect.com/science/article/pii/S0092867423002106
  26. Mar 2023
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    Arresting microbiome development limits immune system maturation and resistance to infection in mice
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    sciencedirect.com/science/article/pii/S1931312823001105
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    Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment
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    sciencedirect.com/science/article/pii/S1535610823000338
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    Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy
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  30. Feb 2023
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    Flow cytometry and immunohistochemistry of the mouse dural meninges for immunological and virological assessments
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    sciencedirect.com/science/article/pii/S2666166723000771
  32. Jan 2023
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    MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors
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    sciencedirect.com/science/article/pii/S1535610822005931
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    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
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    sciencedirect.com/science/article/pii/S107476132200646X
  35. Nov 2022
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T cell deficiency precipitates antibody evasion and emergence of neurovirulent polyomavirus
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    ncbi.nlm.nih.gov/pmc/articles/PMC9674346/
  37. Sep 2022
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    Vaccination-based immunotherapy to target profibrotic cells in liver and lung
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    sciencedirect.com/science/article/pii/S1934590922003769
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    ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
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  40. Jun 2022
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    Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity
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  42. May 2022
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    Intracellular infection and immune system cues rewire adipocytes to acquire immune function
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    sciencedirect.com/science/article/pii/S1550413122001358
  44. Apr 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8736284/
  46. Mar 2022
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    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
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  48. Jan 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malaria
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    ncbi.nlm.nih.gov/pmc/articles/PMC8747512/
  50. Sep 2021
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    CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection
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    sciencedirect.com/science/article/pii/S2211124721011438
  52. Aug 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection
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      DOI: 10.7554/eLife.69975

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    ncbi.nlm.nih.gov/pmc/articles/PMC8315795/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1016/j.immuni.2018.10.007

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    ncbi.nlm.nih.gov/pmc/articles/PMC6303219/
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    sciencedirect.com/science/article/pii/S2211124718318175
  56. Jul 2021
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    Untitled document
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    Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy
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      DOI: 10.1016/j.celrep.2019.05.041

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    pubmed.ncbi.nlm.nih.gov/31189114/
  59. Apr 2021
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    Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3
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    1. scibot 29 Apr 2021
      anti-CD8 (53-6.7)

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  61. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer
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    Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells
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      DOI: 10.1016/j.cmet.2020.07.008

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  63. www.sciencedirect.com www.sciencedirect.com
    Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome
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      DOI: 10.1016/j.chom.2021.03.015

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  64. www.sciencedirect.com www.sciencedirect.com
    Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity
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      DOI: 10.1016/j.ccell.2020.05.020

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  65. www.sciencedirect.com www.sciencedirect.com
    Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity
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      DOI: 10.1016/j.cmet.2021.03.002

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  66. Dec 2020
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses
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      DOI: 10.7554/eLife.57950

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  68. Sep 2020
  69. www.sciencedirect.com www.sciencedirect.com
    Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization
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      DOI: 10.1016/j.celrep.2020.107679

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  70. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Coordinated Viral Control by Cytotoxic Lymphocytes Ensures Optimal Adaptive NK Cell Responses
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    An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint
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      DOI: 10.1016/j.cell.2020.04.030

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    Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis
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      DOI: 10.1016/j.celrep.2020.01.099

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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bmal1 integrates mitochondrial metabolism and macrophage activation
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  74. Jan 2020
  75. www.sciencedirect.com www.sciencedirect.com
    Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency
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      RRID:AB_493703

      DOI: 10.1016/j.celrep.2019.10.044

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  76. www.cell.com www.cell.com
    PD-1 Imposes Qualitative Control of Cellular Transcriptomes in Response to T Cell Activation
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      RRID:AB_493703

      DOI: 10.1016/j.molcel.2019.12.012

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    Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
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      RRID:AB_493703

      DOI: 10.1016/j.molcel.2019.08.005

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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
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      RRID:AB_493703

      DOI: 10.1016/j.ccell.2019.08.003

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  79. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      RRID:AB_493703

      DOI: 10.1016/j.celrep.2019.03.083

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  80. Nov 2018
  81. www.sciencedirect.com www.sciencedirect.com
    Transcription Factor IRF8 Orchestrates the Adaptive Natural Killer Cell Response
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    sciencedirect.com/science/article/pii/S1074761318301870
  82. Nov 2017
  83. www.sciencedirect.com www.sciencedirect.com
    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
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      RRID:AB_493703

      Curator: @Jmenke

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