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Coordinated changes in stromal and hematopoietic cells that define the perinatal to juvenile transition in the mouse thymus

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  DOI: 10.1016/j.celrep.2025.116677
  
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sciencedirect.com:5037/science/article/pii/S2211124725014494
Nov 2025
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GM-CSF and specific type 2 cytokines induce CD103+ and CD301b+ cell states in cDC1s and cDC2s

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Obesity promotes urinary tract infection by disrupting bladder focal adhesion kinase signaling

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1. scibot 15 Nov 2025
  
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  DOI: 10.1016/j.isci.2025.113862
  
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sciencedirect.com/science/article/pii/S2589004225021236
Oct 2025
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Molnupiravir inhibits Bourbon virus infection and disease-associated pathology in mice

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1. scibot 25 Oct 2025
  
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  DOI: 10.1128/jvi.00740-25
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12548437/
Sep 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225017997-main-html.html

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52.53.155.43/e30a4682b87b0f107ed8cb8348c0b6cde5bc2c00/1-s2.0-S2589004225017997-main-html.html
Aug 2025
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Anchored screening identifies transcription factor blueprints underlying dendritic cell diversity and subset-specific anti-tumor immunity

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  DOI: 10.1016/j.immuni.2025.08.001
  
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Protocol to develop a 3D mouse autologous lung tumor-immune spheroid co-culture model to advance radiotherapy-based treatments

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  DOI: 10.1016/j.xpro.2025.104021
  
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sciencedirect.com/science/article/pii/S2666166725004277
Jul 2025
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BRD9 inhibition overcomes oncolytic virus therapy resistance in glioblastoma

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1. scibot 31 Jul 2025
  
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Intracrine VEGF Signaling Is Required for Adult Hippocampal Neural Stem Cell Maintenance and Vascular Proximity

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1. scibot 30 Jul 2025
  
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  DOI: 10.1007/s12035-025-04861-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12289830/
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Glucose restriction shapes pre-metastatic innate immune landscapes in the lung through exosomal TRAIL

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  DOI: 10.1016/j.cell.2025.06.027
  
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The immune response against cancer is modulated by stromal cell fibronectin

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  DOI: 10.1016/j.neo.2025.101196
  
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sciencedirect.com/science/article/pii/S1476558625000764
Jun 2025
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Lymph node fibroblast phenotypes and immune crosstalk regulated by podoplanin activity

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  DOI: 10.1016/j.celrep.2025.115908
  
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52.53.155.43 52.53.155.43

pdf-html.html

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1. scibot 12 Jun 2025
  
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  DOI: 10.1158/2326-6066.cir-24-0797
  
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52.53.155.43/714962b4df611138463d94a4796d134a4c0f1b27/pdf-html.html
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Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis

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1. scibot 11 Jun 2025
  
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  DOI: 10.1084/jem.20240109
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12139521/
May 2025
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MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer

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  DOI: 10.1016/j.celrep.2025.115722
  
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Ribonuclease activity undermines immune sensing of naked extracellular RNA

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1. scibot 19 May 2025
  
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  DOI: 10.1016/j.xgen.2025.100874
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12143340/
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Selective requirement of glycosphingolipid synthesis for natural killer and cytotoxic T cells

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.007
  
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sciencedirect.com/science/article/pii/S009286742500409X
Apr 2025
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Targeting the dendritic cell-secreted immunoregulatory cytokine CCL22 alleviates radioresistance

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1. scibot 02 Apr 2025
  
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  DOI: 10.1158/1078-0432.CCR-23-3616
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11444901/
Mar 2025
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 14 Mar 2025
  
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  DOI: 10.1101/2025.03.05.639198
  
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52.53.155.43/6a1077851a93128037200ab8bc35f1d4060f0db6/PDF-html.html
Feb 2025
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Macrophage-derived CTSS drives the age-dependent disruption of the blood-CSF barrier

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  DOI: 10.1016/j.neuron.2025.01.023
  
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sciencedirect.com/science/article/pii/S0896627325000492
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Rev-erb-α antagonism in alveolar macrophages protects against pneumococcal infection in elderly mice

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  DOI: 10.1016/j.celrep.2025.115273
  
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Dec 2024
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Fibroblast-Mediated Macrophage Recruitment Supports Acute Wound Healing

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  DOI: 10.1016/j.jid.2024.10.609
  
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sciencedirect.com/science/article/pii/S0022202X24029567
Nov 2024
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Pericancerous cross-presentation to cytotoxic T lymphocytes impairs immunotherapeutic efficacy in hepatocellular carcinoma

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1. scibot 21 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.012
  
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Sep 2024
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Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity

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  DOI: 10.1016/j.cell.2024.08.007
  
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Jul 2024
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Tumor necrosis factor regulates leukocyte recruitment but not bacterial persistence during Staphylococcus aureus craniotomy infection

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1. scibot 26 Jul 2024
  
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  DOI: 10.1186/s12974-024-03174-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11264501/
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Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in colorectal cancer

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  DOI: 10.1016/j.ccell.2024.06.009
  
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sciencedirect.com/science/article/pii/S1535610824002344
Jun 2024
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The alarmin IL-33 exacerbates pulmonary inflammation and immune dysfunction in SARS-CoV-2 infection

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1. scibot 30 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110117
  
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cell.com/iscience/abstract/S2589-0042(24)01342-7
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Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss

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  DOI: 10.1016/j.cell.2024.05.003
  
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May 2024
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G-protein-coupled receptor 84 regulates acute inflammation in normal and diabetic skin wounds

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1. scibot 30 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114288
  
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  DOI: 10.1016/j.celrep.2024.114288
  
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An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis

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  DOI: 10.1016/j.cell.2024.04.018
  
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Tuft cell-derived acetylcholine promotes epithelial chloride secretion and intestinal helminth clearance

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  DOI: 10.1016/j.immuni.2024.03.023
  
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The Gut Microbiome Controls Liver Tumors via the Vagus Nerve

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1. scibot 09 May 2024
  
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  BioLegend catalogue #101222
  
  DOI: 10.1101/2024.01.23.576951
  
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biorxiv.org/content/10.1101/2024.01.23.576951v1
Apr 2024
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Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy

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1. scibot 24 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114141
  
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CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer

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1. scibot 12 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101479
  
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Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection

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Feb 2024
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Inflammatory dendritic cells restrain CD11b+CD4+ CTLs via CD200R in human NSCLC

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Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

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FLT3L-dependent dendritic cells control tumor immunity by modulating Treg and NK cell homeostasis

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Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin

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Voluntary exercise does not always suppress lung cancer progression

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Epigenetic Regulation of Leukocyte Inflammatory Mediator Production Dictates Staphylococcus aureus Craniotomy Infection Outcome

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CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance

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Jun 2023
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Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation

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Bone marrow Adipoq-lineage progenitors are a major cellular source of M-CSF that dominates bone marrow macrophage development, osteoclastogenesis, and bone mass

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Jan 2023
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Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma

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CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy

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Tissue-specific transcriptional profiles and heterogeneity of natural killer cells and group 1 innate lymphoid cells

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A neutrophil–B-cell axis impacts tissue damage control in a mouse model of intraabdominal bacterial infection via Cxcr4

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Sep 2022
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Yin and Yang of Cannabinoid CB1 receptor: CB1 Deletion in Immune Cells Causes Exacerbation While CB1 Deletion in Non-immune Cells Attenuates Obesity

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Aug 2022
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https://medrxiv.org/cgi/content/10.1101/2021.05.11.21256877

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Jul 2022
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IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage

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Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice

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Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacy

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Mycobacterium tuberculosis impedes CD40-dependent notch signaling to restrict Th17 polarization during infection

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Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity

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Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response

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A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

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Jan 2022
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ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

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Nov 2021
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CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection

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ILC3s control airway inflammation by limiting T cell responses to allergens and microbes

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A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia

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Cold exposure protects from neuroinflammation through immunologic reprogramming

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tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche

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IL-33 causes thermogenic failure in aging by expanding dysfunctional adipose ILC2

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Untitled document

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CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment

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Untitled document

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Production of the Cytokine VEGF-A by CD4+ T and Myeloid Cells Disrupts the Corneal Nerve Landscape and Promotes Herpes Stromal Keratitis

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IgE Effector Mechanisms, in Concert with Mast Cells, Contribute to Acquired Host Defense against Staphylococcus aureus

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Feb 2021
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Microfilariae Trigger Eosinophil Extracellular DNA Traps in a Dectin-1-Dependent Manner

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1. scibot 28 Feb 2021
  
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  DOI: 10.1016/j.celrep.2020.108621
  
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sciencedirect.com/science/article/pii/S2211124720316107
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Selective inhibition of anti‐MAG IgM autoantibody binding to myelin by an antigen specific glycopolymer

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1. scibot 25 Feb 2021
  
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  DOI: 10.1111/jnc.15021
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15021
Jan 2021
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Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma

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1. scibot 21 Jan 2021
  
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  DOI: 10.1016/j.celrep.2020.108620
  
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Distinct developmental pathways from blood monocytes generate human lung macrophage diversity

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  DOI: 10.1016/j.immuni.2020.12.003
  
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sciencedirect.com/science/article/pii/S1074761320305318
Oct 2020
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BPS Publications

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1. scibot 30 Oct 2020
  
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  DOI: 10.1111/bph.15226
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15226
Sep 2020
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Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.02.005
  
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sciencedirect.com/science/article/pii/S1074761320300765
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Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance

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1. scibot 15 Sep 2020
  
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  DOI: 10.1371/journal.ppat.1008354
  
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journals.plos.org/plospathogens/article
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Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants

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1. scibot 06 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.03.011
  
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sciencedirect.com/science/article/pii/S1074761320301242
Jan 2020
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Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.11.065
  
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sciencedirect.com/science/article/pii/S2211124719315566
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Class-Switch Recombination Occurs Infrequently in Germinal Centers

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.07.001
  
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cell.com/immunity/abstract/S1074-7613(19)30317-6
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A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cell.2019.04.040
  
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Staphylococcus aureus Leukocidins Target Endothelial DARC to Cause Lethality in Mice

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  DOI: 10.1016/j.chom.2019.01.015
  
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sciencedirect.com/science/article/pii/S1931312819300538
Nov 2018
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Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6365216/
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Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells

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Nov 2017
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia

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pmc.ncbi.nlm.nih.gov/articles/PMC7360335/

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